公开(公告)号：US07993361B2

公开(公告)日：2011-08-09

申请号：US11093451

申请日：2005-03-30

Applicant: Michael Maschke

Inventor： Michael Maschke

IPC: A61M29/00

CPC classification number: A61B17/3207 ,  A61B90/37

Abstract: Device for removing a total vascular occlusion with the aid of a CTO catheter with expansion tongs arranged at the front end and OCT monitoring, the CTO catheter being combined with an OCT catheter to form an integrated unit.

Abstract translation: 借助于具有布置在前端的扩张钳的CTO导管和OCT监测来去除总血管闭塞的装置，CTO导管与OCT导管组合以形成一体的单元。

公开(公告)号：US20100332254A1

公开(公告)日：2010-12-30

申请号：US12492329

申请日：2009-06-26

Applicant: Michael Maschke ,  Sebastian Schmidt ,  Gudrun Zahlmann

Inventor： Michael Maschke ,  Sebastian Schmidt ,  Gudrun Zahlmann

IPC: G06Q50/00 ,  A61B5/00 ,  G06N5/02 ,  A61B6/00

CPC classification number: A61B6/481 ,  A61B5/201 ,  A61B5/411 ,  A61B5/7275 ,  G06Q50/24

Abstract: A system and method of diagnosing kidney syndromes using an intravenous pyelogram (IVP) is described. The system includes an X-ray imaging device and an in-vitro diagnostic (IVD) device. The IVD device is used to identify risk factors such as sensitivity to contrast agents, or to indicate or rule out other syndromes which may have symptoms similar to kidney malfunction. The level of blood components such as creatinine may be used, in conjunction with other medical data and IVD tests, to determine a risk score for the patient. The risk score may be used to recommend modifications to a baseline procedure such as change in the volume or type of contrast agent, the number of X-rays, or the performance of post-procedure dialysis.

Abstract translation: 描述了使用静脉肾盂造影（IVP）诊断肾综合征的系统和方法。 该系统包括X射线成像装置和体外诊断（IVD）装置。 IVD装置用于识别对造影剂的敏感性等危险因素，或指示或排除可能具有类似于肾功能障碍的症状的其他综合征。 可以结合其他医疗数据和IVD测试来使用血液成分如肌酐的水平来确定患者的风险评分。 风险评分可用于推荐对基线程序的修改，例如造影剂的体积或类型的变化，X射线的数量或手术后透析的表现。

公开(公告)号：US20100241147A1

公开(公告)日：2010-09-23

申请号：US12719880

申请日：2010-03-09

Applicant: Michael Maschke

Inventor： Michael Maschke

IPC: A61B17/22

CPC classification number: A61B17/320016 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/02007 ,  A61B5/411 ,  A61B5/6852 ,  A61B5/7207 ,  A61B8/06 ,  A61B8/12 ,  A61B17/3207 ,  A61B17/320783 ,  A61M25/0147 ,  A61M25/0158 ,  A61M2025/0166 ,  G01R33/285

Abstract: A catheter for removing plaque in a blood vessel and a medical apparatus comprising a catheter of this kind are proposed. The catheter has a catheter sheath, a cutter for removing plaque disposed in the region of the distal end of the catheter sheath, a catheter tip disposed in the region of the distal end of the catheter sheath and bendable relative to the catheter sheath, and at least one imaging sensor arranged in the region of the distal end of the catheter sheath or in the bendable catheter tip. The image signals recorded by means of the catheter are transmitted for display purposes to an image processing and playback device. A method for assisting a minimally invasive intervention to remove plaque in a blood vessel by the catheter is also provided.

Abstract translation: 提出了用于去除血管中斑块的导管和包括这种导管的医疗装置。 导管具有导管护套，用于去除设置在导管护套的远端的区域中的斑块的切割器，设置在导管护套的远端的区域中并相对于导管护套弯曲的导管末端，并且在 至少一个成像传感器布置在导管护套的远端或可弯曲的导管尖端的区域中。 通过导管记录的图像信号被传输以用于显示目的到图像处理和回放装置。 还提供了一种用于辅助微创干预以通过导管去除血管中的斑块的方法。

公开(公告)号：US20100228101A1

公开(公告)日：2010-09-09

申请号：US12397856

申请日：2009-03-04

Applicant: Michael Maschke ,  Sebastian Schmidt

Inventor： Michael Maschke ,  Sebastian Schmidt

IPC: A61B5/00 ,  A61M37/00

CPC classification number: A61B6/504 ,  A61B5/0022 ,  A61B5/031 ,  A61B5/055 ,  A61B6/03 ,  G06F19/321 ,  G06F19/3418 ,  G06F19/3481 ,  G16H10/40

Abstract: A method and apparatus for diagnosing and treating stroke is described. A preliminary diagnosis of a stroke and the type of stroke is made based on a patient anamnesis and an in-vitro diagnostic device (IVD), configured to analyze biomarkers in a patient blood sample. In one example, the diagnosis is confirmed using a C-arm X-ray device and, if a hemorrhagic stroke is confirmed, interventional therapy may be performed using the C-arm X-ray device to guide a catheter or other interventional device. Where an ischemic stroke is confirmed, the appropriate thrombolytic therapy may be administered. The IVD device may be located in an emergency vehicle, and the test may be results transmitted to the medical facility while the patient is in transit.

Abstract translation: 描述了用于诊断和治疗中风的方法和装置。 基于患者体检和体外诊断装置（IVD）进行中风的初步诊断和中风类型，其被配置为分析患者血液样品中的生物标志物。 在一个示例中，使用C臂X射线装置确认诊断，并且如果确认出血性中风，则可以使用C臂X射线装置进行介入治疗以引导导管或其他介入装置。 在确认缺血性中风的情况下，可以施用适当的溶栓治疗。 IVD装置可以位于紧急车辆中，并且该测试可以在患者在运送期间将结果传送到医疗设施。

公开(公告)号：US20100174555A1

公开(公告)日：2010-07-08

申请号：US12318648

申请日：2009-01-05

Applicant: Klaus Abraham-Fuchs ,  Karsten Hiltawsky ,  Michael Maschke ,  Sebastian Schmidt ,  Gudrun Zahlmann

Inventor： Klaus Abraham-Fuchs ,  Karsten Hiltawsky ,  Michael Maschke ,  Sebastian Schmidt ,  Gudrun Zahlmann

IPC: G06Q50/00 ,  G06N5/02 ,  G06F17/30

CPC classification number: G06Q50/22 ,  G06F19/328 ,  G06F19/3481 ,  G06Q10/04 ,  G06Q10/10 ,  G06Q50/24 ,  G16H50/20

Abstract: At least one embodiment of the present invention refers to a method, a system, a computer readable medium and/or a computer program product for optimizing a clinical pathway. The clinical pathway includes a sequence of actions. In at least one embodiment, he method aims at finding the best suitable and optimal following action for a respective action. There is provided a set of rules, patient information data and optimization criteria. After having received a symptom or an action there is deduced a set of possible following actions. After having deduced all possible following actions, these possible following actions are evaluated by the optimization criteria. After evaluation the optimal following action is suggested as a result.

Abstract translation: 本发明的至少一个实施例涉及用于优化临床途径的方法，系统，计算机可读介质和/或计算机程序产品。 临床路径包括一系列动作。 在至少一个实施例中，他的方法旨在找到针对相应动作的最佳适合和最优跟随动作。 提供了一组规则，患者信息数据和优化标准。 在收到症状或行动后，推断出一组可能的以下行动。 在推导了所有可能的以下操作之后，这些可能的以下操作将通过优化标准进行评估。 评估结果后，建议采用最佳的追踪措施。

公开(公告)号：US07748900B2

公开(公告)日：2010-07-06

申请号：US11827015

申请日：2007-07-10

Applicant: Michael Maschke

Inventor： Michael Maschke

IPC: H05G1/02

CPC classification number: B25J11/00 ,  A61B6/102 ,  A61B6/4405 ,  A61B6/4441 ,  A61B6/4458 ,  A61B6/547 ,  A61B6/548 ,  B25J5/00 ,  G05B2219/37569 ,  G05B2219/40252 ,  G05B2219/45169

Abstract: There is described an x-ray system with an x-ray source, an x-ray detector and at least one industrial robot having at least three, in particular six, axes of rotation, in which the x-ray source and/or the x-ray detector are/is arranged, directly or by means of a bearer, on the industrial robot, and where the industrial robot is constructed to be mobile, in particular is arranged on a device trolley.

Abstract translation: 描述了具有x射线源，x射线检测器和至少一个具有至少三个，特别是六个旋转轴线的工业机器人的x射线系统，其中x射线源和/或 X射线检测器直接地或者通过承载件被布置在工业机器人上，并且工业机器人被构造为可移动的，特别地布置在设备手推车上。

公开(公告)号：US20100143919A1

公开(公告)日：2010-06-10

申请号：US12591915

申请日：2009-12-04

Applicant: Klaus Abraham-Fuchs ,  Karsten Hiltawsky ,  Michael Maschke ,  Sebastian Schmidt

Inventor： Klaus Abraham-Fuchs ,  Karsten Hiltawsky ,  Michael Maschke ,  Sebastian Schmidt

IPC: C12Q1/68 ,  G01N33/68

CPC classification number: C12Q1/6883 ,  C12Q2600/106 ,  G01N33/6893 ,  G01N2800/042

Abstract: An in vitro assay is disclosed for early diagnosis of insulin-dependent diabetes mellitus type 1. In at least one embodiment, the assay includes i) determining susceptibility markers for diabetes mellitus type 1 in a biological sample from a symptom-free individual; ii) determining inflammatory markers in the same or in a further biological sample from the individual; iii) determining the presence or the risk of developing insulin-dependent diabetes mellitus type 1 on the basis of the values obtained in i) and ii); and, possibly, iv) performing step ii) after a defined time interval or v) performing an imaging method for the pancreas. At least one embodiment is further directed to the use of this assay for monitoring the progression of a diabetes mellitus type 1 disease.

Abstract translation: 公开了用于胰岛素依赖性糖尿病1型的早期诊断的体外测定。在至少一个实施方案中，测定包括i）确定来自无症状个体的生物样品中1型糖尿病的易感性标志物; ii）确定来自个体的相同或其它生物样品中的炎症标记; iii）基于i）和ii）中获得的值确定1型胰岛素依赖性糖尿病的存在或风险; 并且可能地，iv）在限定的时间间隔之后执行步骤ii）或v）执行胰腺的成像方法。 至少一个实施方案进一步涉及该测定用于监测1型糖尿病疾病进展的用途。

公开(公告)号：US20090234220A1

公开(公告)日：2009-09-17

申请号：US12380788

申请日：2009-03-03

Applicant: Michael Maschke

Inventor： Michael Maschke

IPC: A61M25/06 ,  A61B6/00 ,  A61B5/055 ,  A61B8/12

CPC classification number: A61B8/12 ,  A61B1/05 ,  A61B5/055 ,  A61B5/411 ,  A61B5/721 ,  A61B34/20 ,  A61B90/361 ,  A61B90/98 ,  A61B2562/17 ,  A61M2025/0089

Abstract: A catheter for treatment of the heart with a flexible catheter sheath surrounding a catheter lumen and with an apparatus for implanting cell material, which comprises an injection apparatus arranged in an area of the catheter tip, is to be created such that the risk of such an intervention is reduced in relation to previously known and practiced concepts. To this end there is inventive provision for at least one imaging sensor to be arranged in the area of the catheter tip.

Abstract translation: 用于用围绕导管内腔的柔性导管鞘和用于植入细胞材料的装置来治疗心脏的导管，其包括布置在导管尖端的区域中的注射装置，使得这样的 相对于以前已知和实践的概念，干预减少了。 为此，本发明提供了至少一个成像传感器布置在导管尖端的区域中。

公开(公告)号：US20090213997A1

公开(公告)日：2009-08-27

申请号：US12378802

申请日：2009-02-19

Applicant: Michael Maschke

Inventor： Michael Maschke

IPC: H05G1/00

CPC classification number: A61B6/04 ,  A61B6/4423 ,  A61B34/20 ,  A61B90/39 ,  A61B2034/2051 ,  A61B2034/2072 ,  A61B2090/3983 ,  A61B2090/3995 ,  A61G13/12 ,  A61G2210/50

Abstract: A medical cushion is provided. The medical cushion has at least one x-ray positive and at least one electromagnetic marker and a soft filler material that yields to the force exerted by the weight of a patient and molds itself at least to some extent to the surface of the body of the patient is provided. The soft filler material is arranged in the cushion in such a manner that it lies between the surface of the body of the patient and at least one x-ray positive and at least one electromagnetic marker when the cushion is in use.

Abstract translation: 提供医用垫。 医用衬垫具有至少一个x射线正面和至少一个电磁标记物和软填充材料，其产生由患者的重量施加的力，并至少在一定程度上模制自身的身体的表面 提供病人 柔软的填充材料以这样一种方式被布置在衬垫中，使得当衬垫使用时，其位于患者身体的表面和至少一个x射线正面和至少一个电磁标记之间。

公开(公告)号：US20080312519A1

公开(公告)日：2008-12-18

申请号：US12157352

申请日：2008-06-10

Applicant: Michael Maschke

Inventor： Michael Maschke

IPC: A61B5/05 ,  C12Q1/68

CPC classification number: A61B5/0205 ,  A61B5/021 ,  A61B5/02438 ,  A61B5/029 ,  A61B5/0402 ,  A61B5/0816 ,  A61B5/145 ,  A61B5/4076 ,  A61B8/00 ,  A61B8/4472 ,  A61B8/56 ,  A61B8/565 ,  A61M16/021 ,  A61M2230/04 ,  A61M2230/202 ,  A61M2230/205 ,  A61M2230/30 ,  A61M2230/42 ,  G06F19/3481 ,  G16H40/63

Abstract: An examination unit, which can be used especially in the area of acute and intensive diagnostics in hospitals (e.g. in emergency rooms, intensive care units, operating theaters etc.) or in ambulances is provided. The examination unit which at least has an ultrasonic device, patient monitor, ECG, ventilator and/or resuscitation device for monitoring the vital functions and/or for the immediate medical treatment of emergency patients with symptoms of acute cardiovascular disease, myocardial infarction, angina, apoplectic stroke, etc. The device furthermore according to the invention includes an integrated mini-laboratory analysis unit for the biochemical and/or cell-biology investigation of blood samples or tissue biopsies.

Abstract translation: 提供了可用于医院急诊和强化诊断领域（例如在急诊室，重症监护室，手术室等）或救护车中的检查单元。 所述检查单元至少具有用于监测急性心血管疾病，心肌梗塞，心绞痛，心绞痛，急性心肌梗塞， 中风中风等。根据本发明的装置还包括用于血液样品或组织活组织检查的生物化学和/或细胞生物学调查的集成微型实验室分析单元。