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11.发明申请公开(公告)号：US20050079224A1
公开(公告)日：2005-04-14
申请号：US10956092
申请日：2004-10-04
Applicant: Michael Rickey , J. Ramstack , Rajesh Kumar
Inventor： Michael Rickey , J. Ramstack , Rajesh Kumar
IPC: B65D5/462 , A61K9/16 , A61K31/519 , A61K38/00 , A61K38/04 , A61K47/32 , A61K47/34 , B01J8/02 , B01J13/08 , B01J13/12 , B01J13/20 , B01J14/00 , B01J19/12 , B01J19/24 , B65D5/46 , B65D5/465 , B65D71/00 , B65D71/36 , A61K38/09 , A61K9/50 , B01J13/02 , B01J13/04
CPC classification number: A61K38/09 , A61K9/1641 , A61K9/1647 , A61K9/1682 , A61K9/1694 , A61K9/5089 , A61K31/519 , B01J8/025 , B01J13/08 , B01J13/12 , B01J13/206 , B01J14/00 , B01J19/121 , B01J19/122 , B01J19/2415 , B01J2219/0877
Abstract: Methods for preparing microparticles having reduced residual solvent levels. Microparticles are contacted with a non-aqueous washing system to reduce the level of residual solvent in the microparticles. Preferred non-aqueous washing systems include 100% ethanol and a blend of ethanol and heptane. A solvent blend of a hardening solvent and a washing solvent can be used to harden and wash microparticles in a single step, thereby eliminating the need for a post-hardening wash step.
Abstract translation: 制备具有降低的残留溶剂水平的微粒的方法。 微粒与非水洗涤体系接触以降低微粒中残留溶剂的含量。 优选的非水洗涤系统包括100％乙醇和乙醇与庚烷的混合物。 可以使用硬化溶剂和洗涤溶剂的溶剂共混物在一个步骤中硬化和洗涤微粒，从而不需要后硬化洗涤步骤。
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12.发明申请公开(公告)号：US20080050447A1
公开(公告)日：2008-02-28
申请号：US11826383
申请日：2007-07-13
Applicant: Michael Rickey , J. Ramstack , Rajesh Kumar
Inventor： Michael Rickey , J. Ramstack , Rajesh Kumar
CPC classification number: A61K38/09 , A61K9/1641 , A61K9/1647 , A61K9/1682 , A61K9/1694 , A61K9/5089 , A61K31/519 , B01J8/025 , B01J13/08 , B01J13/12 , B01J13/206 , B01J14/00 , B01J19/121 , B01J19/122 , B01J19/2415 , B01J2219/0877
Abstract: Methods for preparing microparticles having reduced residual solvent levels. Microparticles are contacted with a non-aqueous washing system to reduce the level of residual solvent in the microparticles. Preferred non-aqueous washing systems include 100% ethanol and a blend of ethanol and heptane. A solvent blend of a hardening solvent and a washing solvent can be used to harden and wash microparticles in a single step, thereby eliminating the need for a post-hardening wash step.
Abstract translation: 制备具有降低的残留溶剂水平的微粒的方法。 微粒与非水洗涤体系接触以降低微粒中残留溶剂的含量。 优选的非水洗涤系统包括100％乙醇和乙醇与庚烷的混合物。 可以使用硬化溶剂和洗涤溶剂的溶剂共混物在一个步骤中硬化和洗涤微粒，从而不需要后硬化洗涤步骤。
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公开(公告)号：US20080051561A1
公开(公告)日：2008-02-28
申请号：US11826382
申请日：2007-07-13
Applicant: Michael Rickey , J. Ramstack , Rajesh Kumar
Inventor： Michael Rickey , J. Ramstack , Rajesh Kumar
IPC: C07K14/00
CPC classification number: A61K38/09 , A61K9/1641 , A61K9/1647 , A61K9/1682 , A61K9/1694 , A61K9/5089 , A61K31/519 , B01J8/025 , B01J13/08 , B01J13/12 , B01J13/206 , B01J14/00 , B01J19/121 , B01J19/122 , B01J19/2415 , B01J2219/0877
Abstract: Methods for preparing microparticles having reduced residual solvent levels. Microparticles are contacted with a non-aqueous washing system to reduce the level of residual solvent in the microparticles. Preferred non-aqueous washing systems include 100% ethanol and a blend of ethanol and heptane. A solvent blend of a hardening solvent and a washing solvent can be used to harden and wash microparticles in a single step, thereby eliminating the need for a post-hardening wash step.
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公开(公告)号：US20070196499A1
公开(公告)日：2007-08-23
申请号：US11785638
申请日：2007-04-19
Applicant: Michael Rickey , J. Ramstack , Rajesh Kumar
Inventor： Michael Rickey , J. Ramstack , Rajesh Kumar
CPC classification number: A61K38/09 , A61K9/1641 , A61K9/1647 , A61K9/1682 , A61K9/1694 , A61K9/5089 , A61K31/519 , B01J8/025 , B01J13/08 , B01J13/12 , B01J13/206 , B01J14/00 , B01J19/121 , B01J19/122 , B01J19/2415 , B01J2219/0877
Abstract: Methods for preparing microparticles having reduced residual solvent levels. Microparticles are contacted with a non-aqueous washing system to reduce the level of residual solvent in the microparticles. Preferred non-aqueous washing systems include 100% ethanol and a blend of ethanol and heptane. A solvent blend of a hardening solvent and a washing solvent can be used to harden and wash microparticles in a single step, thereby eliminating the need for a post-hardening wash step.
Abstract translation: 制备具有降低的残留溶剂水平的微粒的方法。 微粒与非水洗涤体系接触以降低微粒中残留溶剂的含量。 优选的非水洗涤系统包括100％乙醇和乙醇与庚烷的混合物。 可以使用硬化溶剂和洗涤溶剂的溶剂共混物在一个步骤中硬化和洗涤微粒，从而不需要后硬化洗涤步骤。
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公开(公告)号：US20070166352A1
公开(公告)日：2007-07-19
申请号：US11521091
申请日：2006-09-14
Applicant: Steven Wright , Troy Christenson , Thean Yeoh , Michael Rickey , Joyce Hotz , Rajesh Kumar , Mark Fineman , Christine Smith , John Ong , David Lokensgard , Henry Costantino
Inventor： Steven Wright , Troy Christenson , Thean Yeoh , Michael Rickey , Joyce Hotz , Rajesh Kumar , Mark Fineman , Christine Smith , John Ong , David Lokensgard , Henry Costantino
IPC: A61K39/395 , A61K38/28 , A61K38/27 , A61K38/26 , A61K38/43
CPC classification number: A61K47/34 , A61K9/0002 , A61K9/1647 , A61K9/1694 , A61K9/5089 , A61K31/573 , A61K38/2278 , A61K38/26
Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
Abstract translation: 本发明涉及用于持续释放生物活性多肽的组合物，以及形成和使用所述组合物用于持续释放生物活性多肽的方法。 本发明的缓释组合物包含分散在其中的生物相容性聚合物，生物活性多肽和糖。
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Patent Agency Ranking
公开(公告)号：US20060110423A1
公开(公告)日：2006-05-25
申请号：US11107550
申请日：2005-04-15
Applicant: Steven Wright , Troy Christenson , Thean Yeoh , Michael Rickey , Joyce Hotz , Rajesh Kumar , Henry Costantino , David Lokensgard , Christine Smith
Inventor： Steven Wright , Troy Christenson , Thean Yeoh , Michael Rickey , Joyce Hotz , Rajesh Kumar , Henry Costantino , David Lokensgard , Christine Smith
CPC classification number: A61K9/1647 , A61K9/0024 , A61K9/1623 , A61K9/1694 , A61K38/2278 , A61K38/26
Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
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公开(公告)号：US20050271702A1
公开(公告)日：2005-12-08
申请号：US11104877
申请日：2005-04-13
Applicant: Steven Wright , Troy Christensen , Thean Yeoh , Michael Rickey , Joyce Hotz , Rajesh Kumar , Henry Costantino
Inventor： Steven Wright , Troy Christensen , Thean Yeoh , Michael Rickey , Joyce Hotz , Rajesh Kumar , Henry Costantino
IPC: A61K9/00 , A61K9/16 , A61K9/50 , A61K38/09 , A61K38/17 , A61K38/18 , A61K38/19 , A61K38/20 , A61K38/21 , A61K38/22 , A61K38/24 , A61K38/26 , A61K38/27 , A61K38/28 , A61K38/33 , A61K38/35 , A61K47/26 , A61K47/38
CPC classification number: A61K47/34 , A61K9/0024 , A61K9/1623 , A61K9/1647 , A61K9/1694 , A61K38/2278 , A61K38/26 , A61K47/26 , A61K47/38
Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
Abstract translation: 本发明涉及用于持续释放生物活性多肽的组合物，以及形成和使用所述组合物用于持续释放生物活性多肽的方法。 本发明的缓释组合物包含分散在其中的生物相容性聚合物，生物活性多肽和糖。
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公开(公告)号：US10685947B2
公开(公告)日：2020-06-16
申请号：US15869637
申请日：2018-01-12
Applicant: Wilfred Gomes , Mark T. Bohr , Rajesh Kumar , Robert L. Sankman , Ravindranath V. Mahajan , Wesley D. Mc Cullough
Inventor： Wilfred Gomes , Mark T. Bohr , Rajesh Kumar , Robert L. Sankman , Ravindranath V. Mahajan , Wesley D. Mc Cullough
IPC: H01L23/48 , H01L25/18 , H01L25/00 , H01L23/00 , H01L23/538 , H01L23/522 , H01L25/16 , H01L25/065 , H01L23/498
Abstract: The present disclosure is directed to systems and methods of conductively coupling a plurality of relatively physically small core dies to a relatively physically larger base die using an electrical mesh network that is formed in whole or in part in, on, across, or about all or a portion of the base die. Electrical mesh networks beneficially permit the positioning of the cores in close proximity to support circuitry carried by the base die. The minimal separation between the core circuitry and the support circuitry advantageously improves communication bandwidth while reducing power consumption. Each of the cores may include functionally dedicated circuitry such as processor core circuitry, field programmable logic, memory, or graphics processing circuitry. The use of core dies beneficially and advantageously permits the use of a wide variety of cores, each having a common or similar interface to the electrical mesh network.
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公开(公告)号：US09719011B2
公开(公告)日：2017-08-01
申请号：US13126905
申请日：2009-10-29
Applicant: Christopher M. Tanguay , John Erickson , Victoria Manea , Jyh-Chiarng Huarng , Rajesh Kumar , Fikri Emrah Alemdaroglu
Inventor： Christopher M. Tanguay , John Erickson , Victoria Manea , Jyh-Chiarng Huarng , Rajesh Kumar , Fikri Emrah Alemdaroglu
Abstract: A proppant comprises a particle and a polycarbodiimide coating disposed on the particle. The polycarbodiimide coating comprises the reaction product of a polymeric isocyanate and a monomeric isocyanate, in the presence of a catalyst. A method of forming the proppant comprises the steps of providing the particle, providing the polymeric isocyanate, providing the monomeric isocyanate, providing the catalyst, reacting the polymeric isocyanate and the monomeric isocyanate in the presence of the catalyst to form the polycarbodiimide coating, and coating the particle with the polycarbodiimide coating.
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公开(公告)号：US09535865B2
公开(公告)日：2017-01-03
申请号：US13996107
申请日：2011-12-22
Applicant: Thomas P. Thomas , Randy B. Osborne , Rajesh Kumar
Inventor： Thomas P. Thomas , Randy B. Osborne , Rajesh Kumar
IPC: G06F13/00 , G06F13/364 , G06F13/14 , G06F13/40 , G06F13/42 , G06F3/0488 , G06F13/16
CPC classification number: G06F13/364 , G06F3/0488 , G06F13/14 , G06F13/16 , G06F13/4068 , G06F13/4273 , Y02D10/14 , Y02D10/151
Abstract: An interface. A first set of single-ended transmitter circuits reside on a first die having a master device. A first set of single-ended receiver circuits reside on a second die. The receiver circuits have no termination and no equalization. The second die has a slave device responsive to the master device of the first die. Conductive lines connect the first set of transmitter circuits and the first set of receiver circuits. The lengths of the conductive lines are matched.
Abstract translation: 一个接口 第一组单端发射器电路驻留在具有主器件的第一管芯上。 第一组单端接收器电路驻留在第二管芯上。 接收器电路没有终端，没有均衡。 第二管芯具有响应于第一管芯的主器件的从器件。 导电线连接第一组发射器电路和第一组接收器电路。 导线的长度相匹配。
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