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公开(公告)号:US06252044B1
公开(公告)日:2001-06-26
申请号:US08977555
申请日:1997-11-25
申请人: Michael Terance Black , Lisa Kathleen Shilling , Robert King Stodola , Richard Lloyd Warren , Anna Lisa Kosmatka , Richard Oakley Nicholas , Leslie Marie Palmer , Michael Arthur Lonetto , Jason Craig Fedon , John Edward Hodgson , David Justin Charles Knowles
发明人: Michael Terance Black , Lisa Kathleen Shilling , Robert King Stodola , Richard Lloyd Warren , Anna Lisa Kosmatka , Richard Oakley Nicholas , Leslie Marie Palmer , Michael Arthur Lonetto , Jason Craig Fedon , John Edward Hodgson , David Justin Charles Knowles
IPC分类号: C07K100
CPC分类号: C12N9/1085 , A61K38/00 , A61K39/00 , C07K14/3156 , C12N9/1205 , C12N9/78 , C12Y205/01009 , C12Y207/01002
摘要: The invention provides ribB polypeptides and polynucleotides encoding ribB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribB polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供ribB多肽和编码ribB多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ribB多肽筛选抗菌化合物的方法。
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公开(公告)号:US06335424B1
公开(公告)日:2002-01-01
申请号:US08979616
申请日:1997-11-25
申请人: Michael Terence Black , Christine Debouck , Jason Craig Fedon , John Edward Hodgson , Deborah Dee Jaworski , David Justin Charles Knowles , Anna Lisa Kosmatka , Jeffrey Mooney , Richard Oakley Nicholas , Leslie Marie Palmer , Lisa Kathleen Shilling , Robert King Stodola , Min Wang , Richard Lloyd Warren , Yi Yi Zhong
发明人: Michael Terence Black , Christine Debouck , Jason Craig Fedon , John Edward Hodgson , Deborah Dee Jaworski , David Justin Charles Knowles , Anna Lisa Kosmatka , Jeffrey Mooney , Richard Oakley Nicholas , Leslie Marie Palmer , Lisa Kathleen Shilling , Robert King Stodola , Min Wang , Richard Lloyd Warren , Yi Yi Zhong
IPC分类号: A61K3902
CPC分类号: C07K14/3156 , A61K38/00 , A61K39/00 , C12N9/1205 , C12N9/78 , C12N9/80 , C12N9/90 , C12N15/52 , C12Y207/01002
摘要: The invention provides ribG polypeptides and polynucleotides encoding ribG polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribG polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供ribG多肽和编码ribG多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ribG多肽筛选抗菌化合物的方法。
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公开(公告)号:US06284878B1
公开(公告)日:2001-09-04
申请号:US08991023
申请日:1997-12-15
申请人: Michael Arthur Lonetto , Deborah Dee Jaworski , Min Wang , Richard Lloyd Warren , Christopher Michael Traini , Anna Lisa Kosmatka , David Justin Charles Knowles , John Edward Hodgson , Michael Terence Black , David J. Holmes , Richard Oakley Nicholas , Robert King Stodola
发明人: Michael Arthur Lonetto , Deborah Dee Jaworski , Min Wang , Richard Lloyd Warren , Christopher Michael Traini , Anna Lisa Kosmatka , David Justin Charles Knowles , John Edward Hodgson , Michael Terence Black , David J. Holmes , Richard Oakley Nicholas , Robert King Stodola
IPC分类号: C07H2102
CPC分类号: C12N9/1205 , A61K38/00 , A61K39/00 , C07K14/3156 , C12N9/78 , C12N9/80 , C12Y207/01002
摘要: The invention provides def1 polypeptides and polynucleotides encoding def1 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing def1 polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了def1多肽和编码def1多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用def1多肽筛选抗菌化合物的方法。
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公开(公告)号:US06346393B1
公开(公告)日:2002-02-12
申请号:US08965087
申请日:1997-11-06
申请人: Jason Craig Fedon , Michael Arthur Lonetto , Leslie Marie Palmer , Martin Rosenberg , Richard Lloyd Warren
发明人: Jason Craig Fedon , Michael Arthur Lonetto , Leslie Marie Palmer , Martin Rosenberg , Richard Lloyd Warren
IPC分类号: C12N1531
摘要: The invention provides RncS polypeptides and DNA (RNA) encoding RncS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing RncS polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了RncS多肽和编码RncS多肽的DNA(RNA)以及通过重组技术产生此类多肽的方法。 还提供了利用RncS多肽筛选抗菌化合物的方法。
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公开(公告)号:US06326462B1
公开(公告)日:2001-12-04
申请号:US09491916
申请日:2000-01-27
申请人: Christine Debouck , Jason Craig Fedon , Deborah Dee Jaworski , Jeffrey Mooney , Leslie Marie Palmer , Christopher Michael Traini , Min Wang , Richard Lloyd Warren , Yi Yi Zhong
发明人: Christine Debouck , Jason Craig Fedon , Deborah Dee Jaworski , Jeffrey Mooney , Leslie Marie Palmer , Christopher Michael Traini , Min Wang , Richard Lloyd Warren , Yi Yi Zhong
IPC分类号: A61K3902
CPC分类号: C12N9/1085 , A61K38/00
摘要: The invention provides ribH polypeptides and polynucleotides encoding ribH polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribH polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供ribH多肽和编码ribH多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ribH多肽筛选抗菌化合物的方法。
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公开(公告)号:US06222026B1
公开(公告)日:2001-04-24
申请号:US09149624
申请日:1998-09-08
IPC分类号: C12N1531
CPC分类号: C07K14/31
摘要: The invention provides gcp polypeptides and polynucleotides encoding gcp polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gcp polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了gcp多肽和编码gcp多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用gcp多肽筛选抗菌化合物的方法。
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公开(公告)号:US06274361B1
公开(公告)日:2001-08-14
申请号:US09080662
申请日:1998-05-18
申请人: Sanjoy Biswas , Martin K. R. Burnham , Andrew P. Fosberry , John E Hodgson , Elizabeth J Lawlor , Tong Li , Damien McDevitt , Christopher Michael Traini , Martin Rosenberg , Judith Ward , Richard Lloyd Warren , Magdalena Zalacain
发明人: Sanjoy Biswas , Martin K. R. Burnham , Andrew P. Fosberry , John E Hodgson , Elizabeth J Lawlor , Tong Li , Damien McDevitt , Christopher Michael Traini , Martin Rosenberg , Judith Ward , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号: C12N916
CPC分类号: C12N9/18
摘要: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供第p多肽和编码第p多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用第p多肽筛选抗菌化合物的方法。
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公开(公告)号:US06410688B1
公开(公告)日:2002-06-25
申请号:US09373953
申请日:1999-08-13
IPC分类号: C07K100
摘要: The invention provides Def1 polypeptides and DNA (RNA) encoding Def1 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Def1 polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了Def1多肽和编码Def1多肽的DNA(RNA)以及通过重组技术生产此类多肽的方法。 还提供了利用Def1多肽筛选抗菌化合物的方法。
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公开(公告)号:US06180387B2
公开(公告)日:2001-01-30
申请号:US08964652
申请日:1997-11-05
申请人: Sanjoy Biswas , Martin Karl Russel Burnham , Michael Arthur Lonetto , Patrick Vernon Warren , Richard Lloyd Warren
发明人: Sanjoy Biswas , Martin Karl Russel Burnham , Michael Arthur Lonetto , Patrick Vernon Warren , Richard Lloyd Warren
IPC分类号: C12N978
CPC分类号: C12N9/1096 , A61K38/00 , A61K39/00 , C12N9/78
摘要: The invention provides arginine deiminase polypeptides and DNA (RNA) encoding arginine deiminase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing arginine deiminase polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了精氨酸脱亚胺酶多肽和编码精氨酸去亚胺酶多肽的DNA(RNA),以及通过重组技术产生此类多肽的方法。 还提供了利用精氨酸去酰亚胺酶多肽筛选抗菌化合物的方法。
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公开(公告)号:US5866370A
公开(公告)日:1999-02-02
申请号:US964631
申请日:1997-11-05
申请人: Sanjoy Biswas , Martin Karl Russel Burnham , Michael Arthur Lonetto , Patrick Vernon Warren , Richard Lloyd Warren
发明人: Sanjoy Biswas , Martin Karl Russel Burnham , Michael Arthur Lonetto , Patrick Vernon Warren , Richard Lloyd Warren
IPC分类号: G01N33/50 , A61K31/00 , A61K38/00 , A61K39/09 , A61K39/395 , A61K45/00 , A61K48/00 , A61P1/00 , A61P11/00 , A61P13/00 , A61P13/02 , A61P13/08 , A61P15/00 , A61P27/00 , A61P27/02 , A61P31/00 , A61P31/04 , A61P43/00 , C07K16/40 , C12N9/52 , C12N15/00 , C12N15/09 , C12N15/57 , C12R1/445 , G01N33/15 , G01N33/566 , C12N1/20 , C12N15/11
CPC分类号: C12N9/52
摘要: The invention provides aminopeptidase polypeptides and DNA (RNA) encoding aminopeptidase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing aminopeptidase polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供氨基肽酶多肽和编码氨基肽酶多肽的DNA(RNA)和通过重组技术产生这种多肽的方法。 还提供了利用氨肽酶多肽筛选抗菌化合物的方法。
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