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公开(公告)号：US09011884B2
公开(公告)日：2015-04-21
申请号：US13865068
申请日：2013-04-17
Applicant: MicroVention, Inc.
Inventor： Michael Constant , Edward Michael Keeley , Joshua Garretson , Gregory M. Cruise
CPC classification number: A61L31/048 , A61K9/0019 , A61K9/0024 , A61K47/30 , A61K47/34 , A61K49/0404 , A61K49/126 , A61K51/1213 , A61L31/145 , A61L31/18 , A61L2430/36 , Y10T428/298 , C08L33/26
Abstract: Described herein are apparatus, compositions, systems and methods for occluding vascular structures and vascular malformations with radiopaque hydrogel filaments. The filaments can contain no support members and can be CT and MR compatible. Methods of forming such filaments are also disclosed.
Abstract translation: 本文描述的是用不透射线水凝胶细丝阻塞血管结构和血管畸形的装置，组合物，系统和方法。 长丝不能含有支撑构件，可以兼容CT和MR。 还公开了形成这种细丝的方法。
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公开(公告)号：US20130336917A1
公开(公告)日：2013-12-19
申请号：US13917323
申请日：2013-06-13
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
IPC: A61K31/785
CPC classification number: A61K31/785 , A61K9/0024 , A61K31/78 , A61K47/32 , A61L24/0089 , A61L24/046 , A61L2430/36
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
Abstract translation: 描述包含聚合物的组合物; 非生理pH溶液; 和可视化代理; 其中所述聚合物可溶于所述非生理pH溶液并且在生理pH下不溶。 公开了形成溶液和聚合物的方法以及治疗用途的方法。
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公开(公告)号：US20130302251A1
公开(公告)日：2013-11-14
申请号：US13865068
申请日：2013-04-17
Applicant: MicroVention, Inc.
Inventor： Michael Constant , Edward Michael Keeley , Joshua Garretson , Gregory M. Cruise
CPC classification number: A61L31/048 , A61K9/0019 , A61K9/0024 , A61K47/30 , A61K47/34 , A61K49/0404 , A61K49/126 , A61K51/1213 , A61L31/145 , A61L31/18 , A61L2430/36 , Y10T428/298 , C08L33/26
Abstract: Described herein are apparatus, compositions, systems and methods for occluding vascular structures and vascular malformations with radiopaque hydrogel filaments. The filaments can contain no support members and can be CT and MR compatible. Methods of forming such filaments are also disclosed.
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公开(公告)号：US11998563B2
公开(公告)日：2024-06-04
申请号：US17744192
申请日：2022-05-13
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
CPC classification number: A61K31/785 , A61K9/0024 , A61K31/78 , A61L24/0089 , A61L24/046 , A61K47/32 , A61L2430/36
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号：US20220273700A1
公开(公告)日：2022-09-01
申请号：US17744192
申请日：2022-05-13
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
IPC: A61K31/785 , A61K9/00 , A61K31/78 , A61L24/00 , A61L24/04
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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Patent Agency Ranking
公开(公告)号：US10588923B2
公开(公告)日：2020-03-17
申请号：US16232929
申请日：2018-12-26
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号：US10328458B2
公开(公告)日：2019-06-25
申请号：US13781385
申请日：2013-02-28
Applicant: MicroVention, Inc.
Inventor： Joshua Garretson , John Belletto , Gregory M. Cruise
IPC: B05D5/00 , C09D171/08 , B05D3/14 , C08G18/48 , C08G18/78 , C09D175/08 , A61L29/08 , A61L31/10
Abstract: Described herein are methods of coating both metallic and polymeric surfaces adding hydrophilicity comprising the steps mixing a coating composition comprising at least one polyol, at least one compound having at least two isocyanate groups, and an organic solvent; introducing nucleophilic functional groups on the surface thereby creating an active surface; subjecting the active surface to the coating composition thereby forming a coated surface; and curing the coated surface. Medical devices, for example, implantable medical devices can be coated by the methods described herein.
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公开(公告)号：US20190134078A1
公开(公告)日：2019-05-09
申请号：US16232929
申请日：2018-12-26
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
IPC: A61K31/785 , A61L24/00 , A61K9/00 , A61L24/04 , A61K31/78
CPC classification number: A61K31/785 , A61K9/0024 , A61K31/78 , A61K47/32 , A61L24/0089 , A61L24/046 , A61L2430/36
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号：US09937201B2
公开(公告)日：2018-04-10
申请号：US15142395
申请日：2016-04-29
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
CPC classification number: A61K31/785 , A61K9/0024 , A61K31/78 , A61K47/32 , A61L24/0089 , A61L24/046 , A61L2430/36
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号：US09351993B2
公开(公告)日：2016-05-31
申请号：US13917323
申请日：2013-06-13
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
CPC classification number: A61K31/785 , A61K9/0024 , A61K31/78 , A61K47/32 , A61L24/0089 , A61L24/046 , A61L2430/36
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
Abstract translation: 描述包含聚合物的组合物; 非生理pH溶液; 和可视化代理; 其中所述聚合物可溶于所述非生理pH溶液并且在生理pH下不溶。 公开了形成溶液和聚合物的方法以及治疗用途的方法。
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