Method of making a three dimensional cell culture matrix
    11.
    发明授权
    Method of making a three dimensional cell culture matrix 失效
    制作三维细胞培养基质的方法

    公开(公告)号:US08080418B2

    公开(公告)日:2011-12-20

    申请号:US12075093

    申请日:2008-03-07

    IPC分类号: C12M3/00

    摘要: This invention relates three dimensional porous cell culture matrices or scaffolds which have directional porous structure. More particularly, this invention relates to three dimensional porous cell culture matrices or scaffolds for cell culture which are derived from or contain gums including naturally occurring gums, plant gums, galactomannan gums or derivatives thereof. The invention also relates to methods of making the matrices, articles of manufacture (e.g., cell culture vessels and labware) having such matrices or scaffolds, methods of applying these materials to cell culture surfaces, and methods of using cell culture vessels having these three dimensional porous cell culture matrices or scaffolds.

    摘要翻译: 本发明涉及具有定向多孔结构的三维多孔细胞培养基质或支架。 更具体地,本发明涉及用于细胞培养的三维多孔细胞培养基质或支架,其衍生自或含有包括天然存在的树胶,植物胶,半乳甘露聚糖树胶或其衍生物的树胶。 本发明还涉及制备具有这种基质或支架的基质,制品(例如,细胞培养容器和实验器皿)的方法,以及将这些材料应用于细胞培养物表面的方法,以及使用具有这些三维的细胞培养容器的方法 多孔细胞培养基质或支架。

    Gum coatings for cell culture, methods of manufacture and methods of use
    14.
    发明申请
    Gum coatings for cell culture, methods of manufacture and methods of use 审中-公开
    用于细胞培养的胶涂层,制造方法和使用方法

    公开(公告)号:US20080220526A1

    公开(公告)日:2008-09-11

    申请号:US12075079

    申请日:2008-03-07

    IPC分类号: C12N5/06 C12M1/00 B05D3/00

    摘要: This invention relates to coatings for cell culture surfaces. More particularly, this invention relates to coatings for cell culture surfaces which are derived from or contain gums including naturally occurring gums, plant gums, galactomannan gums or derivatives thereof. The invention also relates to articles of manufacture (e.g., cell culture vessels and labware) having such coatings, methods of applying these coatings to cell culture surfaces, and methods of using coated cell culture vessel.

    摘要翻译: 本发明涉及细胞培养物表面的涂层。 更具体地说,本发明涉及来自或含有包括天然存在的树胶,植物胶,半乳甘露聚糖胶或其衍生物的树胶的细胞培养物表面的涂层。 本发明还涉及具有这种涂层的制品(例如,细胞培养容器和实验器皿),将这些涂层施用于细胞培养表面的方法以及使用包被的细胞培养容器的方法。

    SPACED PROJECTION SUBSTRATES AND DEVICES FOR CELL CULTURE
    17.
    发明申请
    SPACED PROJECTION SUBSTRATES AND DEVICES FOR CELL CULTURE 审中-公开
    间隔投影基质和细胞培养装置

    公开(公告)号:US20100129908A1

    公开(公告)日:2010-05-27

    申请号:US12622079

    申请日:2009-11-19

    IPC分类号: C12N5/071

    摘要: An article for culturing cells includes a substrate on which cells can be cultured. The substrate has a base surface. An array of projections extends from the base surface. The projections have a height of about 1 micrometer to about 100 micrometers, and have a gap distance along the major surface from center to center between neighboring projections of about 10 micrometers to 80 micrometers. A plurality of arrays of projections may extend from the surface with gaps in the base surface between the arrays. Hepatocytes cultures on such microprojection array substrates maintained in vivo like morphology and membrane polarity. Hepatocytes co-cultured with helper cells on such substrates tended to grow in the area of the arrays, while the helper cells tended to grow in the areas between the arrays.

    摘要翻译: 培养细胞的制品包括可以培养细胞的底物。 基板具有基面。 一组突起从基面延伸出来。 突起具有约1微米至约100微米的高度,并且在约10微米至80微米的相邻突起之间具有从中心到中心的主表面的间隙距离。 多个突起阵列可以从阵列之间的基部表面中的间隙从表面延伸。 在这样的微喷射阵列基板上的肝细胞培养物保持体内,如形态和膜极性。 与这种底物上的辅助细胞共培养的肝细胞趋向于在阵列区域中生长,而辅助细胞趋向于在阵列之间的区域中生长。

    Prism sheet and backlight module incorporating same
    18.
    发明授权
    Prism sheet and backlight module incorporating same 有权
    棱镜片和并入其的背光模块

    公开(公告)号:US07401967B2

    公开(公告)日:2008-07-22

    申请号:US11414929

    申请日:2006-05-01

    IPC分类号: F21V5/02

    CPC分类号: G02B6/0053 G02B6/0051

    摘要: A prism sheet (10) includes a substrate (12) and a plurality of prism structures (14). The substrate includes a plurality of diffusing particles (122) dispersed therein. The prism structures are at a light output side of the substrate. The diffusing particles can diffuse light beams traveling through the substrate. This configuration performs the same function as that of a diffusing sheet of a conventional backlight module. The prism structures can gather light beams to improve a brightness of a backlight module (6) incorporating the prism sheet. Thus, the backlight module can provide bright and uniform light at a low cost and while having a reduced thickness.

    摘要翻译: 棱镜片(10)包括基板(12)和多个棱镜结构(14)。 基板包括分散在其中的多个扩散粒子(122)。 棱镜结构位于基板的光输出侧。 扩散粒子可以漫射穿过衬底的光束。 该配置执行与传统背光模块的漫射片相同的功能。 棱镜结构可以收集光束以提高结合棱镜片的背光模块(6)的亮度。 因此,背光模块可以以低成本提供明亮均匀的光,同时具有减小的厚度。

    Prism sheet and backlight module incorporating same
    19.
    发明申请
    Prism sheet and backlight module incorporating same 有权
    棱镜片和并入其的背光模块

    公开(公告)号:US20060245212A1

    公开(公告)日:2006-11-02

    申请号:US11414929

    申请日:2006-05-01

    IPC分类号: F21V7/04

    CPC分类号: G02B6/0053 G02B6/0051

    摘要: A prism sheet (10) includes a substrate (12) and a plurality of prism structures (14). The substrate includes a plurality of diffusing particles (122) dispersed therein. The prism structures are at a light output side of the substrate. The diffusing particles can diffuse light beams traveling through the substrate. This configuration performs the same function as that of a diffusing sheet of a conventional backlight module. The prism structures can gather light beams to improve a brightness of a backlight module (6) incorporating the prism sheet. Thus, the backlight module can provide bright and uniform light at a low cost and while having a reduced thickness.

    摘要翻译: 棱镜片(10)包括基板(12)和多个棱镜结构(14)。 基板包括分散在其中的多个扩散粒子(122)。 棱镜结构位于基板的光输出侧。 扩散粒子可以漫射穿过衬底的光束。 该配置执行与传统背光模块的漫射片相同的功能。 棱镜结构可以收集光束以提高结合棱镜片的背光模块(6)的亮度。 因此,背光模块可以以低成本提供明亮均匀的光,同时具有减小的厚度。