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公开(公告)号：US20050228260A1
公开(公告)日：2005-10-13
申请号：US10799357
申请日：2004-03-12
申请人： Phillip Burwell , Zihong Guo , Jennifer Matson , Steven Daly , David Shine , Gary Lichttenegger , Jean Bishop , Nick Yeo , Hugh Narciso
发明人： Phillip Burwell , Zihong Guo , Jennifer Matson , Steven Daly , David Shine , Gary Lichttenegger , Jean Bishop , Nick Yeo , Hugh Narciso
CPC分类号： A61N5/0601 , A61B2018/2261 , A61N5/062 , A61N2005/0602 , A61N2005/0652 , A61N2005/1003
摘要： Light generating devices for illuminating portions of vascular tissue, to render photodynamic therapy. In one embodiment, a light source array preferably including a plurality of light emitting diodes, a focusing lens, and a light diffusing element are included in a distal end of a catheter. A balloon is optionally provided to interrupt blood flow that can block the transmission of light, and to center the apparatus in a blood vessel. Optical fibers optionally direct light from the light source to the diffusing element. The light source array can have a radial or linear configuration and can produce more than one wavelength of light for activating different photoreactive agents. Linear light source elements are particularly useful to treat elongate portions of tissue in a vessel. One embodiment intended for use with a conventional balloon catheter integrates light sources into a guidewire.
摘要翻译： 用于照射血管组织部分的光产生装置，以进行光动力疗法。 在一个实施例中，优选地包括多个发光二极管的光源阵列，聚焦透镜和光漫射元件被包括在导管的远端中。 可选地提供气囊以中断可阻挡光的传播的血流，并使装置居中在血管中。 光纤可选地将来自光源的光引导到漫射元件。 光源阵列可以具有径向或线性配置并且可以产生多于一个波长的光以激活不同的光反应剂。 线性光源元件特别适用于处理容器中组织的细长部分。 旨在用于常规气囊导管的一个实施例将光源集成到导丝中。
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公开(公告)号：US20080027517A1
公开(公告)日：2008-01-31
申请号：US11773555
申请日：2007-07-05
申请人： Phillip Burwell , Zihong Guo , Jennifer Matson , Steven Daly , David Shine , Gary Lichttenegger , Jean Bishop , Nick Yeo , Hugh Narciso
发明人： Phillip Burwell , Zihong Guo , Jennifer Matson , Steven Daly , David Shine , Gary Lichttenegger , Jean Bishop , Nick Yeo , Hugh Narciso
IPC分类号： A61N5/06
CPC分类号： A61N5/0601 , A61B2018/2261 , A61N5/062 , A61N2005/0602 , A61N2005/0652 , A61N2005/1003
摘要： Light generating devices for illuminating portions of vascular tissue, to render photodynamic therapy. In one embodiment, a light source array preferably including a plurality of light emitting diodes, a focusing lens, and a light diffusing element are included in a distal end of a catheter. A balloon is optionally provided to interrupt blood flow that can block the transmission of light, and to center the apparatus in a blood vessel. Optical fibers optionally direct light from the light source to the diffusing element. The light source array can have a radial or linear configuration and can produce more than one wavelength of light for activating different photoreactive agents. Linear light source elements are particularly useful to treat elongate portions of tissue in a vessel. One embodiment intended for use with a conventional balloon catheter integrates light sources into a guidewire.
摘要翻译： 用于照射血管组织部分的光产生装置，以进行光动力疗法。 在一个实施例中，优选地包括多个发光二极管的光源阵列，聚焦透镜和光漫射元件被包括在导管的远端中。 可选地提供气囊以中断可阻挡光的传播的血流，并使装置居中在血管中。 光纤可选地将来自光源的光引导到漫射元件。 光源阵列可以具有径向或线性配置并且可以产生多于一个波长的光以激活不同的光反应剂。 线性光源元件特别适用于处理容器中组织的细长部分。 旨在用于常规气囊导管的一个实施例将光源集成到导丝中。
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13.发明授权公开(公告)号：US08821584B2
公开(公告)日：2014-09-02
申请号：US12352508
申请日：2009-01-12
CPC分类号： A61F5/0079 , A61B5/065 , A61B17/12022 , A61B17/1204 , A61B17/12099 , A61B17/12136 , A61B17/12159 , A61B17/12163 , A61B17/12172 , A61B17/1219 , A61B2017/00119 , A61B2017/00221 , A61B2017/22069 , A61M5/14276 , A61M5/1723 , A61M31/002
摘要： The present invention relates to a device for intermittently obstructing a bodily opening, such as a gastric opening, and includes a proximal member connected to a distal member by a tether. The proximal member includes an apron member surrounding a first occluding member, which is formable from an elongated and narrower configuration to a contracted or expanded but wider configuration. When employed in the stomach, the device of the present invention is arranged transluminally, with the distal member disposed in the duodenum and the proximal member disposed against the pyloric valve, intermittently occluding the pyloric valve and preventing or delaying the flow of gastric contents through the pyloric valve. In certain embodiments, a reservoir may be included for releasing a substance of interest, for example for releasing insulin from a reservoir disposed in the distal member. Sensors, actuators, and data transmission devices may also be included.
摘要翻译： 本发明涉及一种用于间歇地阻塞诸如胃开口的身体开口的装置，并且包括通过系绳连接到远端构件的近端构件。 近端构件包括围绕第一闭塞构件的围裙构件，其可从细长且较窄的构造形成为收缩或扩展但更宽的构造。 当在胃中使用时，本发明的装置是平行布置的，其中远端构件设置在十二指肠中，并且近端构件设置在幽门阀上，间歇地闭塞幽门瓣膜，并且防止或延迟胃内容物通过 幽门阀 在某些实施方案中，可以包括储存器以释放感兴趣的物质，例如用于从设置在远端构件中的储存器释放胰岛素。 还可以包括传感器，致动器和数据传输装置。
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公开(公告)号：US20060079943A1
公开(公告)日：2006-04-13
申请号：US11215892
申请日：2005-08-30
申请人： Hugh Narciso
发明人： Hugh Narciso
IPC分类号： A61N1/32
CPC分类号： A61N1/0558 , A61N1/0556 , A61N1/326 , A61N1/36107
摘要： Methods and devices are described for electrically stimulating nerves and organs to induce and modulate the production of hormones according to desired hormone production patterns and hormone level patterns to treat gynecological conditions. Such methods and devices may be used to treat or alleviate the symptoms of menopause. In addition, such methods and devices may be used for birth control.
摘要翻译： 描述了用于电刺激神经和器官的方法和装置，以根据期望的激素生成模式和激素水平模式诱导和调节激素的产生以治疗妇科病症。 这些方法和装置可用于治疗或缓解更年期症状。 此外，这种方法和装置可以用于避孕。
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公开(公告)号：US08888797B2
公开(公告)日：2014-11-18
申请号：US12205403
申请日：2008-09-05
CPC分类号： A61F5/0079 , A61B5/065 , A61B17/12022 , A61B17/1204 , A61B17/12099 , A61B17/12136 , A61B17/12159 , A61B17/12163 , A61B17/12172 , A61B17/1219 , A61B2017/00119 , A61B2017/00221 , A61B2017/22069 , A61M5/14276 , A61M5/1723 , A61M31/002
摘要： The present invention relates to a device for intermittently obstructing a bodily opening, such as a gastric opening, and includes a proximal member connected to a distal member by a tether. The proximal member includes an apron member surrounding a first occluding member, which is formable from an elongated and narrower configuration to a contracted or expanded but wider configuration. When employed in the stomach, the device of the present invention is arranged transluminally, with the distal member disposed in the duodenum and the proximal member disposed against the pyloric valve, intermittently occluding the pyloric valve and preventing or delaying the flow of gastric contents through the pyloric valve. In certain embodiments, a reservoir may be included for releasing a substance of interest, for example for releasing insulin from a reservoir disposed in the distal member. Sensors, actuators, and data transmission devices may also be included.
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公开(公告)号：US08795301B2
公开(公告)日：2014-08-05
申请号：US12352497
申请日：2009-01-12
CPC分类号： A61F5/0079 , A61B5/065 , A61B17/12022 , A61B17/1204 , A61B17/12099 , A61B17/12136 , A61B17/12159 , A61B17/12163 , A61B17/12172 , A61B17/1219 , A61B2017/00119 , A61B2017/00221 , A61B2017/22069 , A61M5/14276 , A61M5/1723 , A61M31/002
摘要： The present invention relates to a device for intermittently obstructing a bodily opening, such as a gastric opening, and includes a proximal member connected to a distal member by a tether. The proximal member includes an apron member surrounding a first occluding member, which is formable from an elongated and narrower configuration to a contracted or expanded but wider configuration. When employed in the stomach, the device of the present invention is arranged transluminally, with the distal member disposed in the duodenum and the proximal member disposed against the pyloric valve, intermittently occluding the pyloric valve and preventing or delaying the flow of gastric contents through the pyloric valve. In certain embodiments, a reservoir may be included for releasing a substance of interest, for example for releasing insulin from a reservoir disposed in the distal member. Sensors, actuators, and data transmission devices may also be included.
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