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1.发明授权公开(公告)号：US08821584B2
公开(公告)日：2014-09-02
申请号：US12352508
申请日：2009-01-12
CPC分类号： A61F5/0079 , A61B5/065 , A61B17/12022 , A61B17/1204 , A61B17/12099 , A61B17/12136 , A61B17/12159 , A61B17/12163 , A61B17/12172 , A61B17/1219 , A61B2017/00119 , A61B2017/00221 , A61B2017/22069 , A61M5/14276 , A61M5/1723 , A61M31/002
摘要： The present invention relates to a device for intermittently obstructing a bodily opening, such as a gastric opening, and includes a proximal member connected to a distal member by a tether. The proximal member includes an apron member surrounding a first occluding member, which is formable from an elongated and narrower configuration to a contracted or expanded but wider configuration. When employed in the stomach, the device of the present invention is arranged transluminally, with the distal member disposed in the duodenum and the proximal member disposed against the pyloric valve, intermittently occluding the pyloric valve and preventing or delaying the flow of gastric contents through the pyloric valve. In certain embodiments, a reservoir may be included for releasing a substance of interest, for example for releasing insulin from a reservoir disposed in the distal member. Sensors, actuators, and data transmission devices may also be included.
摘要翻译： 本发明涉及一种用于间歇地阻塞诸如胃开口的身体开口的装置，并且包括通过系绳连接到远端构件的近端构件。 近端构件包括围绕第一闭塞构件的围裙构件，其可从细长且较窄的构造形成为收缩或扩展但更宽的构造。 当在胃中使用时，本发明的装置是平行布置的，其中远端构件设置在十二指肠中，并且近端构件设置在幽门阀上，间歇地闭塞幽门瓣膜，并且防止或延迟胃内容物通过 幽门阀 在某些实施方案中，可以包括储存器以释放感兴趣的物质，例如用于从设置在远端构件中的储存器释放胰岛素。 还可以包括传感器，致动器和数据传输装置。
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公开(公告)号：US08888797B2
公开(公告)日：2014-11-18
申请号：US12205403
申请日：2008-09-05
CPC分类号： A61F5/0079 , A61B5/065 , A61B17/12022 , A61B17/1204 , A61B17/12099 , A61B17/12136 , A61B17/12159 , A61B17/12163 , A61B17/12172 , A61B17/1219 , A61B2017/00119 , A61B2017/00221 , A61B2017/22069 , A61M5/14276 , A61M5/1723 , A61M31/002
摘要： The present invention relates to a device for intermittently obstructing a bodily opening, such as a gastric opening, and includes a proximal member connected to a distal member by a tether. The proximal member includes an apron member surrounding a first occluding member, which is formable from an elongated and narrower configuration to a contracted or expanded but wider configuration. When employed in the stomach, the device of the present invention is arranged transluminally, with the distal member disposed in the duodenum and the proximal member disposed against the pyloric valve, intermittently occluding the pyloric valve and preventing or delaying the flow of gastric contents through the pyloric valve. In certain embodiments, a reservoir may be included for releasing a substance of interest, for example for releasing insulin from a reservoir disposed in the distal member. Sensors, actuators, and data transmission devices may also be included.
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公开(公告)号：US08795301B2
公开(公告)日：2014-08-05
申请号：US12352497
申请日：2009-01-12
CPC分类号： A61F5/0079 , A61B5/065 , A61B17/12022 , A61B17/1204 , A61B17/12099 , A61B17/12136 , A61B17/12159 , A61B17/12163 , A61B17/12172 , A61B17/1219 , A61B2017/00119 , A61B2017/00221 , A61B2017/22069 , A61M5/14276 , A61M5/1723 , A61M31/002
摘要： The present invention relates to a device for intermittently obstructing a bodily opening, such as a gastric opening, and includes a proximal member connected to a distal member by a tether. The proximal member includes an apron member surrounding a first occluding member, which is formable from an elongated and narrower configuration to a contracted or expanded but wider configuration. When employed in the stomach, the device of the present invention is arranged transluminally, with the distal member disposed in the duodenum and the proximal member disposed against the pyloric valve, intermittently occluding the pyloric valve and preventing or delaying the flow of gastric contents through the pyloric valve. In certain embodiments, a reservoir may be included for releasing a substance of interest, for example for releasing insulin from a reservoir disposed in the distal member. Sensors, actuators, and data transmission devices may also be included.
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公开(公告)号：US09427556B2
公开(公告)日：2016-08-30
申请号：US13306076
申请日：2011-11-29
CPC分类号： A61B18/04 , A61B18/02 , A61B2018/00023 , A61B2018/046 , A61B2090/064 , A61M25/10 , A61M2025/0002 , A61M2025/0003 , A61M2025/0175 , A61M2025/1015 , A61M2025/1052 , A61M2210/105 , A61M2210/1433
摘要： Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure sensing elements which may allow for control of the pressure within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled or room temperature fluid such as water may then be used to rapidly terminate the treatment session.
摘要翻译： 描述了用于治疗体腔或内腔的方法和装置，其中加热的流体和/或气体可以通过导管引入到包含在一个或多个可充气/可膨胀构件之间的体内的治疗区域中。 导管还可以具有可选的压力感测元件，其可以允许控制处理区域内的压力并且还防止压力超过可充气/可膨胀构件的压力，从而容纳这些可充气/可膨胀构件之间的处理区域。 任选地，然后可以使用冷冻或室温流体例如水来快速终止治疗期。
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公开(公告)号：US09204828B2
公开(公告)日：2015-12-08
申请号：US13306335
申请日：2011-11-29
IPC分类号： A61B5/00 , A61B5/145 , A61B5/1455 , A61B5/1459 , A61B5/1473 , A61B5/1486
CPC分类号： A61B5/14532 , A61B5/1455 , A61B5/1459 , A61B5/1473 , A61B5/14865 , A61B5/4839
摘要： A device may be implanted subcutaneously with an attached catheter inserted within, e.g., the peritoneal cavity of a subject. The catheter and/or device may also be inserted into another space, e.g., subcutaneous, vascular, peritoneal, cerebrospinal, pleural spaces, etc. The peritoneal fluid which normally collects and/or flows through the peritoneal cavity may be detected by the catheter and analyzed via the device to detect the concentration of glucose within the fluid.
摘要翻译： 皮下可以将装置植入插入在受试者的例如腹膜腔内的附接的导管。 导管和/或装置也可插入另一空间，例如皮下，血管，腹膜，脑脊液，胸膜腔等。通常通过腹膜腔收集和/或流经的腹膜液可通过导管和 通过装置分析以检测流体内葡萄糖的浓度。
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公开(公告)号：US08430805B2
公开(公告)日：2013-04-30
申请号：US12469625
申请日：2009-05-20
IPC分类号： A61N2/02
摘要： An energy emitting apparatus for providing a medical therapy includes one or more energy generators, a logic controller electrically connected to the one or more energy generators, and one or more sensors for detecting electric conduction in a target nerve that are connected to the logic controller. The one or more energy generators produce energy focused on the target nerve upon receiving a signal from the logic controller, and the energy is varied by the logic controller according to an input provided by the one or more sensors. In one embodiment, the energy emitting apparatus is an apparatus for magnetic induction therapy that includes one or more conductive coils disposed in an ergonomic housing that produce a magnetic field focused on the target nerve upon receiving an electric current from the logic controller based on an input provided by the one or more sensors.
摘要翻译： 用于提供医疗治疗的能量发射装置包括一个或多个能量发生器，电连接到一个或多个能量发生器的逻辑控制器，以及用于检测连接到逻辑控制器的目标神经中的导电的一个或多个传感器。 一个或多个能量发生器在从逻辑控制器接收信号时产生集中在目标神经上的能量，并且根据由一个或多个传感器提供的输入，逻辑控制器改变能量。 在一个实施例中，能量发射装置是用于磁感应治疗的装置，其包括设置在人体工程学外壳中的一个或多个导电线圈，其基于输入端从逻辑控制器接收到电流而产生聚焦在目标神经上的磁场 由一个或多个传感器提供。
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公开(公告)号：US20100204765A1
公开(公告)日：2010-08-12
申请号：US12702165
申请日：2010-02-08
CPC分类号： A61F7/12 , A61F2007/0063 , A61F2007/0069 , A61F2007/0076 , A61F2007/0078 , A61F2007/0093 , A61F2007/126 , A61M1/166 , A61M1/28 , A61M1/285 , A61M1/288 , A61M1/32
摘要： Methods and apparatus for delivering therapeutic hypothermia to a patient are provided which may include any number of features. One feature is a hypothermia system comprising a fluid source, a heat exchanger assembly, a catheter in fluid communication with the fluid source, and a pump system configured to infuse hypothermic fluid into a patient cavity and extract hypothermic fluid from the patient cavity. The hypothermia system can infuse and extract fluid automatically from the patient cavity. In one embodiment, the patient cavity is a peritoneal cavity. A safe access device to gain access to the patient cavity is also provided.
摘要翻译： 提供了向患者递送治疗性体温的方法和装置，其可以包括任何数量的特征。 一个特征是低温系统，其包括流体源，热交换器组件，与流体源流体连通的导管，以及被配置为将低体温流体注入患者空腔并从患者腔抽取低体温流体的泵系统。 低温系统可以自动注入并从患者腔中提取液体。 在一个实施例中，患者腔是腹膜腔。 还提供了进入患者腔的安全通路装置。
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公开(公告)号：US09687243B2
公开(公告)日：2017-06-27
申请号：US12351644
申请日：2009-01-09
CPC分类号： A61B17/12099 , A61B5/036 , A61B5/073 , A61B5/14539 , A61B17/12022 , A61B17/12136 , A61B17/12172 , A61B17/12177 , A61B17/1219 , A61B2017/00818 , A61B2017/00867 , A61B2017/00893 , A61B2017/1205 , A61B2017/12054 , A61B2017/12086 , A61F5/003 , A61F5/0036 , A61F5/0079
摘要： Methods, devices and systems facilitate gastric retention of a variety of therapeutic devices. devices generally include a support portion for preventing the device from passing through the pyloric valve or esophagus wherein a retaining member may optionally be included on the distal end of the positioning member for further maintaining a position of the device in the stomach. Some embodiments are deliverable into the stomach through the esophagus, either by swallowing or through a delivery tube or catheter. Some embodiments are fully reversible. Some embodiments self-expand within the stomach, while others are inflated or otherwise expanded.
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公开(公告)号：US20130226077A1
公开(公告)日：2013-08-29
申请号：US13860426
申请日：2013-04-10
IPC分类号： A61F7/12
CPC分类号： A61F7/12 , A61F7/123 , A61F2007/0063 , A61F2007/0086 , A61F2007/126
摘要： A method of providing hypothermia to a patient including the steps of inserting a fluid delivery member into a peritoneal cavity of the patient; delivering hypothermia fluid from a fluid source into the peritoneal cavity through the delivery member; and limiting fluid pressure within the peritoneal cavity without providing feedback control to the fluid source. The invention also provides an apparatus for practicing the method.
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公开(公告)号：US08439960B2
公开(公告)日：2013-05-14
申请号：US12169566
申请日：2008-07-08
IPC分类号： A61F7/12
CPC分类号： A61F7/12 , A61F7/123 , A61F2007/0063 , A61F2007/0086 , A61F2007/126
摘要： A method of providing hypothermia to a patient including the steps of inserting a fluid delivery member into a peritoneal cavity of the patient; delivering hypothermia fluid from a fluid source into the peritoneal cavity through the delivery member; and limiting fluid pressure within the peritoneal cavity without providing feedback control to the fluid source. The invention also provides an apparatus for practicing the method.
摘要翻译： 一种向患者提供低温的方法，包括将流体递送部件插入患者的腹膜腔中的步骤; 将低温液从流体源通过输送构件输送到腹膜腔中; 并且限制腹腔内的流体压力，而不向流体源提供反馈控制。 本发明还提供了一种用于实施该方法的装置。
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