中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

24 records (took 0.021 seconds)

    Test element for electrochemically detecting at least one an analyte
    14.
    发明授权
    Test element for electrochemically detecting at least one an analyte 有权

    公开(公告)号：US11099149B2

    公开(公告)日：2021-08-24

    申请号：US15604017

    申请日：2017-05-24

    Applicant: Roche Diagnostics Operations, Inc.

    Inventor： Klaus Andreas Bauer-Espindola ,  Michael Marquant ,  Christine Nortmeyer ,  Reiner Stein

    IPC: G01N27/327 ,  C12Q1/00

    Abstract: A test element for electrochemically detecting at least one analyte in a bodily fluid is disclosed. The test element comprises at least one first electrode and at least one second electrode. The first electrode is designed as a working electrode and the second electrode is designed as a counter electrode. The test element comprises at least one capillary capable of receiving a sample of the body fluid. The first electrode and the second electrode are arranged on opposing sides of the capillary. The first electrode and the second electrode are arranged such that during a capillary filling the first electrode and the second electrode are wetted simultaneously and at an equal rate.

    INTERFERENCE COMPENSATING TWO ELECTRODES TEST STRIP
    15.
    发明申请
    INTERFERENCE COMPENSATING TWO ELECTRODES TEST STRIP 审中-公开

    公开(公告)号：US20170240945A1

    公开(公告)日：2017-08-24

    申请号：US15442202

    申请日：2017-02-24

    Applicant: Roche Diagnostics Operations, Inc.

    Inventor： Michael Marquant ,  Michael Reinhardt

    IPC: C12Q1/00 ,  G01N33/49 ,  G01N27/327 ,  G01N33/487

    Abstract: A method of detecting at least one analyte in a test sample is provided comprising a) contacting the test sample (i) to an active chemistry matrix changing at least one electrochemical property dependent on an enzymatic activity active in the presence of the analyte, the active chemistry matrix contacting a first electrode; and (ii) to an inactive chemistry matrix, the inactive chemistry matrix contacting a second electrode, b) closing an electrical circuit including the first electrode, the second electrode, and the active chemistry matrix and inactive chemistry matrix, followed by determining a first value of the at least one electrochemical property, c) inverting electrical polarity of the electrical circuit of b), followed by determining a second value of the at least one electrochemical property, and d) detecting the at least one analyte based on the first value and on the second value.

    AZO MEDIATORS AND METHODS OF USE THEREOF
    17.
    发明申请
    AZO MEDIATORS AND METHODS OF USE THEREOF 有权
    AZO介质及其使用方法

    公开(公告)号：US20140212903A1

    公开(公告)日：2014-07-31

    申请号：US14226884

    申请日：2014-03-27

    Applicant: Roche Diagnostics Operations, Inc.

    Inventor： Stacy H. Duvall ,  Peter Gebauer ,  Dieter Heindl ,  Carina Horn ,  Peter Kratzsch ,  Michael Marquant ,  Thomas Meier

    IPC: C12Q1/54

    CPC classification number: C12Q1/54 ,  C07C281/20 ,  C07D295/215

    Abstract: Azo compounds are disclosed that do not form azoxy dimers and that do not have any reactive nitroso groups. Also disclosed are use of the azo compounds as mediators in optical and electrochemical diagnostic methods, as well as detection reagents, kits and test elements that include such azo compounds and that can be used in the diagnostic methods.

    Abstract translation: 公开了不形成氮氧化二聚体并且不具有任何反应性亚硝基的偶氮化合物。 还公开了在光学和电化学诊断方法中使用偶氮化合物作为介体，以及包括这种偶氮化合物并且可用于诊断方法的检测试剂，试剂盒和测试元件。

    Method and device for determining a concentration of at least one analyte
    18.
    发明授权
    Method and device for determining a concentration of at least one analyte 有权

    公开(公告)号：US11782009B2

    公开(公告)日：2023-10-10

    申请号：US17443260

    申请日：2021-07-23

    Applicant: Roche Diagnostics Operations, Inc.

    Inventor： Michael Marquant ,  Samuel Evgin ,  Melanie Klein

    IPC: G01N27/327

    CPC classification number: G01N27/3274

    Abstract: A method for determining a concentration of at least one analyte in bodily fluid, comprising: a signal generation step, wherein an excitation voltage signal is generated by a signal generator, wherein the excitation voltage signal comprises a poly frequent alternating current (AC) voltage and a direct current (DC) voltage profile, wherein the poly frequent AC voltage comprises at least two frequencies; a signal application step, wherein the excitation voltage signal is applied to at least two measurement electrodes; a measurement step, wherein a response is measured by using the measurement electrodes; an evaluation step, wherein an AC current response for each frequency and a DC current response are evaluated from the response; a determination step, wherein the concentration of the analyte is determined from the DC current response and from one or both of the phase and impedance information by using at least one predetermined relationship.

    Interference compensating two electrodes test strip
    19.
    发明授权
    Interference compensating two electrodes test strip 有权

    公开(公告)号：US11473118B2

    公开(公告)日：2022-10-18

    申请号：US16735773

    申请日：2020-01-07

    Applicant: Roche Diagnostics Operations, Inc.

    Inventor： Michael Marquant ,  Michael Reinhardt

    IPC: G01N27/327 ,  C12Q1/00 ,  G01N33/487 ,  G01N33/49

    Abstract: A method of detecting at least one analyte in a test sample is provided comprising a) contacting the test sample (i) to an active chemistry matrix changing at least one electrochemical property dependent on an enzymatic activity active in the presence of the analyte, the active chemistry matrix contacting a first electrode; and (ii) to an inactive chemistry matrix, the inactive chemistry matrix contacting a second electrode, b) closing an electrical circuit including the first electrode, the second electrode, and the active chemistry matrix and inactive chemistry matrix, followed by determining a first value of the at least one electrochemical property, c) inverting electrical polarity of the electrical circuit of b), followed by determining a second value of the at least one electrochemical property, and d) detecting the at least one analyte based on the first value and on the second value.

    Method and device for determining a concentration of at least one analyte
    20.
    发明授权
    Method and device for determining a concentration of at least one analyte 有权

    公开(公告)号：US11125712B2

    公开(公告)日：2021-09-21

    申请号：US16441282

    申请日：2019-06-14

    Applicant: Roche Diagnostics Operations, Inc.

    Inventor： Michael Marquant ,  Samuel Evgin ,  Melanie Klein

    IPC: G01N27/327

    Abstract: A method for determining a concentration of at least one analyte in bodily fluid, comprising: a signal generation step, wherein an excitation voltage signal is generated by a signal generator, wherein the excitation voltage signal comprises a poly frequent alternating current (AC) voltage and a direct current (DC) voltage profile, wherein the poly frequent AC voltage comprises at least two frequencies; a signal application step, wherein the excitation voltage signal is applied to at least two measurement electrodes; a measurement step, wherein a response is measured by using the measurement electrodes; an evaluation step, wherein an AC current response for each frequency and a DC current response are evaluated from the response; a determination step, wherein the concentration of the analyte is determined from the DC current response and from one or both of the phase and impedance information by using at least one predetermined relationship.

Patent Agency Ranking