公开(公告)号：US08285378B1

公开(公告)日：2012-10-09

申请号：US10950876

申请日：2004-09-27

申请人： Bruce KenKnight ,  Eric Lovett ,  Adam W. Cates ,  Amir Tehrani

发明人： Bruce KenKnight ,  Eric Lovett ,  Adam W. Cates ,  Amir Tehrani

IPC分类号： A61N1/02

CPC分类号： A61N1/37235 ,  A61N1/37282 ,  G06F19/00 ,  G16H40/40

摘要： A system and method for determining patient-specific implantable medical device programming parameters are presented. A set of physiological measures collected through a plurality of sensors monitoring physiological functions in a patient are assimilated. The physiological measures set are analyzed to identify physiological idiosyncrasies specific to the patient and to optimize the therapy to be delivered through an implantable medical device. A patient profile is formed including a plurality of programming parameters and the patient profile is preprogrammed into the implantable medical device prior to implantation in the patient.

摘要翻译： 提出了一种用于确定患者特异性可植入医疗器械编程参数的系统和方法。 通过监测患者生理功能的多个传感器收集的一组生理测量被同化。 分析生理测量集以确定特定于患者的生理特征并优化通过可植入医疗装置递送的治疗。 形成包括多个编程参数的患者轮廓，并且在植入患者之前将患者轮廓预编程到可植入医疗装置中。

公开(公告)号：US20050021097A1

公开(公告)日：2005-01-27

申请号：US10862779

申请日：2004-06-07

申请人： Julie Thompson ,  Eric Lovett ,  Janice Jenkins

发明人： Julie Thompson ,  Eric Lovett ,  Janice Jenkins

IPC分类号： A61N1/362

CPC分类号： A61N1/3622

摘要： An algorithm for detection of tachycardias and for discriminating between supraventricular tachycardia (SVT) and ventricular tachycardia (VT) when a 1:1 tachycardia condition is present that can be implemented in an implantable cardiac rhythm management device. Variability measures of AV and VA intervals during the tachycardia are computed and used to distinguish between SVT and VT.

摘要翻译： 用于检测心动过速的方法，并且当存在可以在可植入的心律管理装置中实施的1：1的心动过速时，区分室上性心动过速（SVT）和室性心动过速（VT）。 计算心动过速期间AV和VA间隔的变异性测量，并用于区分SVT和VT。

公开(公告)号：US20060089694A1

公开(公告)日：2006-04-27

申请号：US10970265

申请日：2004-10-21

申请人： Yongxing Zhang ,  Yunlong Zhang ,  Eric Lovett ,  Bruce Tockman

发明人： Yongxing Zhang ,  Yunlong Zhang ,  Eric Lovett ,  Bruce Tockman

IPC分类号： A61N1/05

CPC分类号： A61N1/056

摘要： A delivery system and method for delivering a pulmonary artery lead into a pulmonary artery includes a delivery device having an inflatable balloon at a distal end. The device is inserted into the venous system, the balloon is inflated and the device is floated along a blood flow path within the venous system through the heart and into the pulmonary artery. The lead is delivered into the pulmonary artery using the device. In one embodiment, the device is a catheter that facilitates placement of an implantation catheter and/or a guide wire into the pulmonary artery for delivery of the lead. In another embodiment, the lead is mounted over the catheter. In yet another embodiment, the delivery device is formed at the distal end of the lead.

摘要翻译： 用于将肺动脉导管输送到肺动脉的输送系统和方法包括在远端具有可充气气囊的输送装置。 将装置插入静脉系统中，气囊膨胀，并且装置沿静脉系统内的血流通道穿过心脏并进入肺动脉。 使用该装置将铅输送到肺动脉。 在一个实施例中，该装置是便于将植入导管和/或导丝放置到肺动脉中用于输送铅的导管。 在另一个实施例中，引线安装在导管上。 在另一个实施例中，输送装置形成在引线的远端。

公开(公告)号：US20050043652A1

公开(公告)日：2005-02-24

申请号：US10643006

申请日：2003-08-18

申请人： Eric Lovett ,  Robert Sweeney ,  Bruce Kenknight

发明人： Eric Lovett ,  Robert Sweeney ,  Bruce Kenknight

IPC分类号： A61B5/00 ,  A61B5/04 ,  A61B5/113 ,  A61N1/362 ,  A61B5/11

CPC分类号： A61B5/1116 ,  A61B5/00 ,  A61B5/0031 ,  A61B5/04 ,  A61B5/0476 ,  A61B5/0496 ,  A61B5/1135 ,  A61B5/4809 ,  A61B5/4812 ,  A61B5/686 ,  A61B5/7264 ,  A61B5/7267 ,  A61B2560/0468 ,  A61N1/362

摘要： Systems and methods for sleep state classification involve detecting conditions related to sleep, including at least one condition associated with rapid eye movement (REM) sleep. Additionally, a condition modulated by the sleep-wake status of the patient may be detected. A medical system that is partially or fully implantable incorporates sensors and circuitry for detecting and processing the sleep-related signals. A sleep state processor classifies the patient's sleep state based on the sleep-related signals. Sleep state classification may be used in connection with the delivery of sleep state appropriate therapy, diagnostic testing, or patient monitoring.

摘要翻译： 用于睡眠状态分类的系统和方法涉及检测与睡眠相关的病症，包括与快速眼动（REM）睡眠相关的至少一种病症。 此外，可以检测由患者的睡眠 - 唤醒状态调制的状况。 部分或完全可植入的医疗系统包括用于检测和处理睡眠相关信号的传感器和电路。 睡眠状态处理器根据睡眠相关信号对患者的睡眠状态进行分类。 睡眠状态分类可用于与睡眠状态适当的治疗，诊断测试或患者监测的传递有关。

公开(公告)号：US20120271389A1

公开(公告)日：2012-10-25

申请号：US13540218

申请日：2012-07-02

申请人： Adam Cates ,  Eric Lovett ,  Loren Murney ,  Kip Ludwig ,  Paul Pignato ,  Brian Soltis

发明人： Adam Cates ,  Eric Lovett ,  Loren Murney ,  Kip Ludwig ,  Paul Pignato ,  Brian Soltis

IPC分类号： A61N1/375

CPC分类号： A61N1/05 ,  A61N1/0558 ,  A61N1/36117 ,  A61N1/36139 ,  A61N1/36157 ,  A61N1/36171 ,  A61N1/36175 ,  A61N1/36182

摘要： Devices and methods of use for introduction and implantation of an electrode as part of a minimally invasive technique. An implantable baroreflex activation system includes a control system having an implantable housing, an electrical lead, attachable to the control system, and an electrode structure. The electrode structure is near one end of the electrical lead, and includes a monopolar electrode, a backing material having an effective surface area larger than the electrode, and a releasable pivotable interface to mate with an implant tool. The electrode is configured for implantation on an outer surface of a blood vessel and the control system is programmed to deliver a baroreflex therapy via the monopolar electrode to a baroreceptor within a wall of the blood vessel.

摘要翻译： 用于引入和植入电极作为微创技术的一部分的装置和方法。 可植入压力反射激活系统包括具有可植入壳体，可引导到控制系统的电引线和电极结构的控制系统。 电极结构靠近电引线的一端，并且包括单极电极，具有大于电极的有效表面积的背衬材料以及与植入工具配合的可释放的可枢转接口。 电极被配置为植入在血管的外表面上，并且控制系统被编程为通过单极电极将压力反射治疗递送到血管壁内的压力感受器。

公开(公告)号：US20120109250A1

公开(公告)日：2012-05-03

申请号：US13286169

申请日：2011-10-31

申请人： Adam Cates ,  Eric Lovett ,  Loren Murney ,  Kip Ludwig ,  Paul Pignato ,  Brian Soltis

发明人： Adam Cates ,  Eric Lovett ,  Loren Murney ,  Kip Ludwig ,  Paul Pignato ,  Brian Soltis

IPC分类号： A61N1/372

CPC分类号： A61N1/05 ,  A61N1/0558 ,  A61N1/36117 ,  A61N1/36139 ,  A61N1/36157 ,  A61N1/36171 ,  A61N1/36175 ,  A61N1/36182

摘要： Devices and methods of use for introduction and implantation of an electrode as part of a minimally invasive technique. An implantable baroreflex activation system includes a control system having an implantable housing, an electrical lead, attachable to the control system, and an electrode structure. The electrode structure is near one end of the electrical lead, and includes a monopolar electrode, a backing material having an effective surface area larger than the electrode, and a releasable pivotable interface to mate with an implant tool. The electrode is configured for implantation on an outer surface of a blood vessel and the control system is programmed to deliver a baroreflex therapy via the monopolar electrode to a baroreceptor within a wall of the blood vessel.

公开(公告)号：US20070233201A1

公开(公告)日：2007-10-04

申请号：US11759394

申请日：2007-06-07

申请人： Eric Lovett ,  Mark Schwartz

发明人： Eric Lovett ,  Mark Schwartz

IPC分类号： A61N1/18

CPC分类号： A61N1/36514 ,  A61N1/3622 ,  A61N1/36542 ,  A61N1/36564

摘要： A rate smoothing function used in implantable pulse generators uses detected triggering events, which cause the rate smoothing function to be activated or deactivated, and detected parameter adjusting events, which cause parameter(s) of the rate smoothing function to be changed. In one example, the activation/deactivation and/or change to the parameters of the rate smoothing function are temporary, and the pre-event state of the rate smoothing function is set to a post-adjusting state, such as after a first time interval. Rate smoothing may be selected, activated or deactivated, or adjusted based on a cardiac signal state, or based on an activity or other physiological sensor signal. The adjusted rate smoothing parameters may include an up-smoothing percentage to limit a speed of pacing rate increase and a down-smoothing percentage to limit a speed of pacing rate drop.

摘要翻译： 在植入式脉冲发生器中使用的速率平滑功能使用检测到的触发事件，其导致速率平滑功能被激活或去激活，并且检测到参数调整事件，这导致速率平滑功能的参数被改变。 在一个示例中，对速率平滑功能的参数的激活/去激活和/或改变是暂时的，并且速率平滑功能的事件前状态被设置为后调整状态，诸如在第一时间间隔 。 速率平滑可以被选择，激活或去激活，或者基于心脏信号状态或基于活动或其他生理传感器信号进行调整。 经调整的速率平滑参数可以包括上调平滑百分比以限制起搏速率增加的速度和下调平滑百分比以限制起搏速率下降的速度。

公开(公告)号：US20060195163A1

公开(公告)日：2006-08-31

申请号：US11381051

申请日：2006-05-01

申请人： Bruce KenKnight ,  Eric Lovett ,  Robert Sweeney ,  Scott Mazar ,  Yatheendhar Manicka

发明人： Bruce KenKnight ,  Eric Lovett ,  Robert Sweeney ,  Scott Mazar ,  Yatheendhar Manicka

IPC分类号： A61N1/08

CPC分类号： A61N1/36514 ,  A61N1/3627 ,  A61N1/37211 ,  A61N1/37235 ,  A61N1/37282 ,  G06F19/00

摘要： An apparatus and method for adjusting the performance of an implanted device based on data including contextual information. Contextual information, including operational and performance data concerning the implanted device as well as the patient with the implanted device, is stored by a portable electronic device. In one embodiment, the portable electronic device is adapted for battery operation and includes a personal digital assistant (PDA). The portable electronic device is adapted for use as an interface to conduct wireless communications with the implanted device. In one embodiment, the portable electronic device interfaces with a clinical programmer for use by a physician.

摘要翻译： 一种用于基于包括上下文信息的数据来调整植入装置的性能的装置和方法。 上下文信息，包括关于植入装置的操作和性能数据以及具有植入装置的患者，由便携式电子装置存储。 在一个实施例中，便携式电子设备适用于电池操作并且包括个人数字助理（PDA）。 便携式电子设备适于用作与植入的设备进行无线通信的接口。 在一个实施例中，便携式电子设备与临床程序员接口以供医生使用。

公开(公告)号：US20060089693A1

公开(公告)日：2006-04-27

申请号：US10970569

申请日：2004-10-21

申请人： Eric Lovett ,  Bruce Tockman ,  Yongxing Zhang ,  Yunlong Zhang

发明人： Eric Lovett ,  Bruce Tockman ,  Yongxing Zhang ,  Yunlong Zhang

IPC分类号： A61N1/05

CPC分类号： A61N1/056

摘要： A delivery system and method for delivering a right ventricular lead into a right ventricle includes a delivery device having an inflatable balloon at a distal end. The device is inserted into the venous system, the balloon is inflated and the device is floated along a blood flow path within the venous system through the heart and into the pulmonary artery. The lead is delivered into the right ventricle using the device. In one embodiment, the device is a catheter that facilitates placement of a guide wire into the right ventricle for delivery of the lead. The catheter is then removed and the lead is inserted into the right ventricle over the guide wire.

摘要翻译： 用于将右心室导线输送到右心室的输送系统和方法包括具有在远端的可充气气囊的输送装置。 将装置插入静脉系统中，气囊膨胀，并且装置沿静脉系统内的血流通道穿过心脏并进入肺动脉。 使用该装置将铅输送到右心室。 在一个实施例中，该装置是便于将导丝放置到右心室中用于输送引线的导管。 然后取出导管，引导线通过导丝插入右心室。

公开(公告)号：US20060074331A1

公开(公告)日：2006-04-06

申请号：US10955831

申请日：2004-09-30

申请人： Jaeho Kim ,  Joseph Bocek ,  Eric Lovett

发明人： Jaeho Kim ,  Joseph Bocek ,  Eric Lovett

IPC分类号： A61B5/04

CPC分类号： A61B5/7264 ,  A61B5/04525

摘要： Different types of cardiac arrhythmia are classified based on the morphology of the arrhythmic beats. Cardiac beats associated with an arrhythmic episode are compared to a plurality of representative beat morphologies, each representative beat morphology characterizing a type of arrhythmia of the heart. An arrhythmic episode may be classified as a particular type of arrhythmia if the morphology of the arrhythmic cardiac beats matches a representative beat morphology characterizing the particular type of arrhythmia. An appropriate therapy for the particular type of arrhythmia may be selected based on the arrhythmia classification. A particular type of arrhythmia may be associated with one or more therapies used to treat the arrhythmia. The therapy used to treat the arrhythmia may comprise a therapy identified as a previously successful therapy.

摘要翻译： 基于心律失常节律的形态分类不同类型的心律失常。 与心律失常发作相关的心脏搏动与多个代表性搏动形态进行比较，每个代表性搏动形态表征心脏心律失常的类型。 如果心律失常心跳的形态与表征特定类型的心律失常的代表性搏动形态匹配，则心律失常发作可被分类为特定类型的心律失常。 可以基于心律失常分类来选择针对特定类型的心律失常的适当疗法。 特定类型的心律失常可能与用于治疗心律失常的一种或多种治疗相关联。 用于治疗心律失常的治疗可以包括被确定为先前成功的治疗的治疗。