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公开(公告)号：US20150294823A1
公开(公告)日：2015-10-15
申请号：US14547426
申请日：2014-11-19
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Mark Bachman , Guann-Pyng Li , Yang Zhang , Minfeng Wang
CPC classification number: H01H50/32 , B81B3/0054 , B81B2201/016 , H01H1/0036 , H01H50/005 , H01H50/44 , H01H50/58 , H01H2001/0042
Abstract: Micro-electromagnetically actuated latched miniature relay switches formed from laminate layers comprising a spring and magnet, electromagnetic coils, magnetic latching material, and transmission line with contacts. Preferably the miniature relay switches transmit up to about 50 W of DC or AC line power, and carry up to about 10 A of load current, with an overall volume of less than about 100 mm3. In addition to switching large power, the device preferably requires less than 3 V to actuate, and has a latching feature that retains the switch state after actuation without the need for external applied voltage or current.
Abstract translation: 由包括弹簧和磁体的层压层形成的微电磁致动的小型继电器开关，电磁线圈，磁性闭锁材料和具有触点的传输线。 优选地，小型继电器开关传输高达约50W的DC或AC线路功率，并且承载大约10A的负载电流，总体积小于约100mm 3。 除了切换大功率之外，该装置优选地需要小于3V来致动，并且具有锁定特征，其在致动之后保持开关状态，而不需要外部施加的电压或电流。
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公开(公告)号：US11207002B2
公开(公告)日：2021-12-28
申请号：US15312030
申请日：2015-05-18
Applicant: The Regents of the University of California
Inventor： Michelle Khine , Jonathan Pegan , Eugene Lee , Mark Bachman , Joshua Kim , Sun-Jun Park , Gareth Forde , Dorsey Ligon
Abstract: A wearable sensor apparatus is disclosed that includes a flexible substrate adapted to be coupled with a skin surface of an expectant mother. A conductor is disposed on the flexible substrate. The conductor can include micron-scale invaginations. The conductor can be capable of repeatable variation in resistance when subject to a strain. Also disclosed is a system for monitoring the health of a fetus in utero that includes a wearable sensor apparatus. The wearable sensor apparatus is configured to output a signal responsive to an electrical input. The system includes a computing system with one or more hardware processors. The computing system is programmed to implement a signal processing module configured to access the output signal from the wearable strain gauge and generate an output indicative of health of the baby in utero. The output can be based in part on the received output signal and previously stored correlations between signal data from the wearable strain gauge and observations of the system or of the mother. A user interface module can be provided and can be configured to display an output indicative of health of the baby in utero.
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公开(公告)号：US20190321821A1
公开(公告)日：2019-10-24
申请号：US16168020
申请日：2018-10-23
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Mark Bachman , Sarkis Babikian , Guann-Pyng Li
Abstract: A microfluidic component package that is readily integratable within a microfluidic system.
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公开(公告)号：US10161737B2
公开(公告)日：2018-12-25
申请号：US15311990
申请日：2015-05-18
Applicant: The Regents of the University of California
Inventor： Jonathan Pegan , Michelle Khine , Mark Bachman , Joshua Kim , Sun-Jun Park
Abstract: A sensor apparatus including a flexible substrate and a wrinkled conductor disposed on the flexible substrate. In some embodiments, the conductor includes micro-scale invaginations. Also disclosed are methods of making a sensor apparatus, including: placing a mask over a polymeric sheet, wherein the mask is configured to block regions of the polymeric sheet, depositing a conductive structure on the polymeric sheet at regions exposed through the mask, shrinking the polymeric sheet with conductive structure patterned on its surface by heating, and transferring the conductive structure to a flexible substrate. Also disclosed are methods of sensing a health condition of a user or patient. The methods include coupling a sensor apparatus to a surface of a user or patient overlying structures to be monitored. The sensor apparatus may include a crumpled conductor capable of detecting strain. Strain is detected by directing current through the sensor apparatus during flexing of the surface and measuring a characteristic of the sensor apparatus based on the strain to generate an output for a user, indicative of the condition of the user or patient.
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公开(公告)号：US11545265B2
公开(公告)日：2023-01-03
申请号：US15803664
申请日：2017-11-03
Applicant: The Regents of the University of California
Inventor： Michelle Khine , Jonathan Pegan , Eugene Lee , Michael Chu , Francis Duhay , Mark Bachman , Joshua Kim , Sun-Jun Park
Abstract: A mobile medical device for monitoring a respiratory condition in a subject, the medical device including: a sensor configured to be adhered to the skin of a patient, the sensor configured to yield a resistance signal that is modulated by movements of a chest of a patient during respiration; a sensor attachment module configured to receive the signal from the sensor and to output data to a mobile electronic device an indication of an adverse respiratory event. Also disclosed is a server for integrating data collected from a plurality of the mobile medical devices and a crowd-sourced respiration advisory system including a plurality of the mobile medical devices and a server for integrating data collected by the mobile medical devices.
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Patent Agency Ranking
公开(公告)号：US20200253493A1
公开(公告)日：2020-08-13
申请号：US16639366
申请日：2018-08-16
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Mark Bachman , Sarkis Babikian , Guann-Pyng Li
Abstract: A miniature wireless pressure sensor has an inductor and a capacitor. The inductor and the capacitor form a L-C resonator with a resonate frequency. The inductor's inductance is affected by a slidable electro-magnetic element. When an outside pressure is applied onto the element, it causes the element to move and such movement changes the inductance of the inductor. Because of that, the resonate frequency is changed. Therefore, the change in resonate frequency indicates a change in the outside pressure. The L-C resonator is calibrated to correlate with the outside pressure. Such a miniature wireless pressure sensor facilitates the monitoring of physiological pressure in different part of human body such as eyes and cranium.
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公开(公告)号：US10471276B2
公开(公告)日：2019-11-12
申请号：US15766802
申请日：2016-10-07
Applicant: The Regents of the University of California
Inventor： William Beckner , John A. Ives , Mark Bachman , Guann-Pyng Li
Abstract: An apparatus and method utilizes photonics, particularly lasers, and biometric feedback for physiological and neurological stimulation. While many areas of the body are candidates, such laser stimulation is particularly directed to the outer ear. Lasers positioned over the ear stimulate targets on the outer ear for pain and stress management and regulation of the autonomic nervous system to affect symptoms and clinical conditions. Laser positioning, wavelength, aiming, focus, power, power density, timing, and sequencing are managed and modified dynamically in real time to effect a personalized and effective treatment protocol.
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公开(公告)号：US20190113326A1
公开(公告)日：2019-04-18
申请号：US16218297
申请日：2018-12-12
Applicant: The Regents of the University of California
Inventor： Jonathan Pegan , Michelle Khine , Mark Bachman , Joshua Kim , Sun-Jun Park
Abstract: A method of making a sensor apparatus including placing a mask over a polymeric sheet, wherein the mask is configured to block regions of the polymeric sheet, depositing a conductive structure on the polymeric sheet at regions exposed through the mask, shrinking the polymeric sheet with conductive structure patterned on its surface by heating, and transferring the conductive structure to a flexible substrate.
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公开(公告)号：US20170232436A1
公开(公告)日：2017-08-17
申请号：US15355009
申请日：2016-11-17
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Mark Bachman , Wesley A. Cox-Muranami
Abstract: Systems and methods directed to an array of microstructures for biological cell sorting with each individual structure component including an integrated magnetic element.
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20.发明申请CELL IDENTIFICATION SYSTEMS AND METHODS USING FUNCTIONALIZED MICROPALLET ARRAYS 审中-公开细胞鉴定系统和使用功能化微阵列阵列的方法公开(公告)号：US20130337473A1
公开(公告)日：2013-12-19
申请号：US13888299
申请日：2013-05-06
Applicant: The Regents of the University of California
Inventor： Edward L. Nelson , Trisha M. Westerhof , Mark Bachman , Guann-Pyng Li
IPC: G01N33/574
CPC classification number: G01N33/574 , G01N33/56966 , G01N33/56972 , G01N33/56977 , G01N33/57438
Abstract: Cell identification systems and methods using micropallet arrays are disclosed. According to one embodiment, a cell identification strategy involves detecting the expression patterns of markers that are expressed on cells to uniquely identify different cell populations within heterogeneous mixtures of cells. The cell markers may be on the cell surface or intracellular in location. The cell markers are interrogated using monoclonal antibodies (mAbs) that are directly conjugated to flourophores. The mAb-flourophore conjugates are used to detect the presence or absence and relative level of expression of each of the cell markers using laser scanning confocal microscopy.
Abstract translation: 公开了使用微孔阵列的细胞鉴定系统和方法。 根据一个实施方案，细胞鉴定策略涉及检测在细胞上表达的标志物的表达模式以唯一地鉴定细胞异种混合物内的不同细胞群。 细胞标志物可以在细胞表面上或细胞内的位置。 使用直接与荧光体缀合的单克隆抗体（mAb）来询问细胞标记物。 使用激光扫描共聚焦显微镜，使用mAb-荧光共轭物来检测每种细胞标记物的存在或不存在和相对的表达水平。
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