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    Method and apparatus for low coherence interferometry
    12.
    发明授权
    Method and apparatus for low coherence interferometry 有权

    公开(公告)号：US11751762B2

    公开(公告)日：2023-09-12

    申请号：US16719305

    申请日：2019-12-18

    Applicant: Topcon Corporation

    Inventor： Jongsik Kim ,  Ying Dong ,  Song Mei ,  Kinpui Chan ,  Zhenguo Wang ,  Zaixing Mao

    IPC: A61B3/10 ,  A61B3/14 ,  A61B3/12 ,  G01N21/17

    CPC classification number: A61B3/102 ,  A61B3/1225 ,  A61B3/14 ,  G01N21/17 ,  G01N2021/1787

    Abstract: A low coherence imaging method comprises acquiring image data of an object with an interferometric imaging system, where the image data is from a location of the object at first and second times; determining a first depth profile from the image data from the location at the first time and a second depth profile from the image data of the location at the second time; determining a change with respect to depth between the first and second depth profiles; and determining a property, or identifying a location, of at least one dynamic particle in the object based on the change between the first and second depth profiles. The method is able to identify, analyze, and/or visualize dynamic particles with features comparable to at least fluorescein angiography, indocyanine green angiography, confocal scanning laser fluorescein angiography, confocal scanning laser indocyanine green angiography, and fluorescence microscopy images, without the use of a dye.

    3D QUANTITATIVE ANALYSIS WITH DEEP LEARNING
    15.
    发明申请
    3D QUANTITATIVE ANALYSIS WITH DEEP LEARNING 有权

    公开(公告)号：US20210082116A1

    公开(公告)日：2021-03-18

    申请号：US17103058

    申请日：2020-11-24

    Applicant: Topcon Corporation

    Inventor： Zaixing Mao ,  Zhenguo Wang ,  Kinpui Chan ,  Yasufumi Fukuma

    IPC: G06T7/00 ,  G06N20/00 ,  G06N7/00

    Abstract: A machine learning model is trained to identify the texture difference between the different layers of a multilayer object. By training with data in full 3D space, the resulting model is capable of predicting the probability that each pixel in a 3D image belongs to a certain layer. With the resulting probability map, comparing probabilities allows one to determine boundaries between layers, and/or other properties and useful information such as volume data.

    IMAGE QUALITY IMPROVEMENT METHODS FOR OPTICAL COHERENCE TOMOGRAPHY
    16.
    发明申请
    IMAGE QUALITY IMPROVEMENT METHODS FOR OPTICAL COHERENCE TOMOGRAPHY 审中-公开

    公开(公告)号：US20200279352A1

    公开(公告)日：2020-09-03

    申请号：US16797848

    申请日：2020-02-21

    Applicant: Topcon Corporation

    Inventor： Zaixing Mao ,  Zhenguo Wang ,  Kinpui Chan

    IPC: G06T5/00 ,  G06T5/50

    Abstract: Ophthalmological mages generated by coherent imaging modalities have multiple types of noise, including random noise caused by the imaging system and speckle noise caused by turbid objects such as living tissues. These noises can occur at different levels in different locations. A noise-reduction method and system of the present disclosure thus relates to applying different filters for different types of noise and/or different locations of images, sequentially or in parallel and combined, to produce a final noise-reduced image.

    Ophthalmological device
    18.
    发明授权
    Ophthalmological device 有权

    公开(公告)号：US12186020B2

    公开(公告)日：2025-01-07

    申请号：US17594552

    申请日：2020-04-24

    Applicant: Topcon Corporation

    Inventor： Zhenguo Wang ,  Zaixing Mao ,  Kazuhiro Oomori ,  Makoto Fujino

    IPC: A61B3/15 ,  A61B3/12

    Abstract: An ophthalmologic apparatus includes: an objective lens that faces a subject's eye; an alignment light emitting unit that irradiates the subject's eye with alignment light to perform measurement of alignment between the objective lens and the subject's eye; an alignment reflection light receiving unit that receives alignment reflection light, which is a reflection of the alignment light from the subject's eye; an anterior segment camera that receives corneal reflection light; and a holder positioned between the anterior segment camera and the objective lens to hold the anterior segment camera, wherein the holder includes an imaging transmissive portion that transmits the corneal reflection light to the anterior segment camera, a first light-transmissive portion that transmits the alignment light from the alignment light emitting unit, and a second light-transmissive portion that transmits the alignment reflection light from the subject's eye.

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