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    IMIDAZOLIUM-TYPE IONIC OLIGOMERS
    14.
    发明申请
    IMIDAZOLIUM-TYPE IONIC OLIGOMERS 有权
    咪唑型离子低聚物

    公开(公告)号：US20100093975A1

    公开(公告)日：2010-04-15

    申请号：US12530890

    申请日：2008-03-12

    申请人： Tak-Hang Chan ,  Xun He

    发明人： Tak-Hang Chan ,  Xun He

    IPC分类号： C07K7/06 ,  C07D403/14

    CPC分类号： C07D233/61 ,  C07K1/042 ,  C08G73/0616

    摘要： The present disclosure relates to structurally defined imidazolium-type ionic oligomers of the formula: wherein n is an integer ranging from 1 to 20; A is N or m is an integer ranging from 1 to 5; X is selected from the group consisting of Br, OTf, CF3CO2, CH3CO2, BF4, PF6, NTf2, F, Cl and I; and R is selected from the group consisting of hydrogen and C1-10 alkyl. The imidazolium-type ionic oligomers lend themselves as soluble/solid supports for biopolymer synthesis.

    摘要翻译： 本公开涉及结构上定义的下式的咪唑鎓型离子低聚物：其中n是1至20的整数; A为N或m为1至5的整数; X选自Br，OTf，CF 3 CO 2，CH 3 CO 2，BF 4，PF 6，NTf 2，F，Cl和I; 并且R选自氢和C 1-10烷基。 咪唑型离子低聚物本身可用作生物聚合物合成的可溶/固体支持体。

    IONIC LIQUID SUPPORTED SYNTHESIS
    17.
    发明申请
    IONIC LIQUID SUPPORTED SYNTHESIS 有权
    离子液体支持合成

    公开(公告)号：US20100041869A1

    公开(公告)日：2010-02-18

    申请号：US11908487

    申请日：2006-03-15

    申请人： Tak-Hang Chan ,  Masad J. Damha ,  Weishi Miao ,  Robert Alexander Donga ,  Xun He

    发明人： Tak-Hang Chan ,  Masad J. Damha ,  Weishi Miao ,  Robert Alexander Donga ,  Xun He

    IPC分类号： C07K1/00 ,  C07H1/00

    CPC分类号： C07H21/00 ,  C07H3/06 ,  C07K1/023 ,  C07K1/04 ,  Y02P20/542

    摘要： The present invention relates to ionic liquids for use in chemical applications and capable of serving the dual function of solvent and liquid support. The ionic liquid lends itself to a method of synthesizing oligomers selected from the group consisting of oligopeptides, oligosaccharides and oligonucleotides, comprising contacting a first monomer unit with an ionic liquid at reaction conditions to provide an ionic liquid bound monomer unit; and contacting the ionic liquid bound monomer unit with at least one further monomer unit at reaction conditions to provide an ionic liquid bound oligomer comprising from 2 to 30 monomer units. The method lends itself to large scale manufacture of oligopeptides, oligosaccharides and oligonucleotides.

    摘要翻译： 本发明涉及用于化学应用并能够起到溶剂和液体载体的双重作用的离子液体。 离子液体本身适用于合成选自寡肽，寡糖和寡核苷酸的低聚物的方法，包括在反应条件下使第一单体单元与离子液体接触以提供离子液体结合的单体单元; 以及在反应条件下使离子液体结合的单体单元与至少一个其它单体单元接触，以提供包含2至30个单体单元的离子液体结合的低聚物。 该方法适合大规模生产寡肽，寡糖和寡核苷酸。

    Imidazolium-type ionic oligomers
    19.
    发明授权
    Imidazolium-type ionic oligomers 有权
    咪唑鎓型离子低聚物

    公开(公告)号：US08168801B2

    公开(公告)日：2012-05-01

    申请号：US12530890

    申请日：2008-03-12

    申请人： Tak-Hang Chan ,  Xun He

    发明人： Tak-Hang Chan ,  Xun He

    IPC分类号： C07D403/06 ,  C07D403/14

    CPC分类号： C07D233/61 ,  C07K1/042 ,  C08G73/0616

    摘要： The present disclosure relates to structurally defined imidazolium-type ionic oligomers of the formula: wherein n is an integer ranging from 1 to 20; A is N or m is an integer ranging from 1 to 5; X is selected from the group consisting of Br, OTf, CF3CO2, CH3CO2, BF4, PF6, NTf2, F, Cl and I; and R is selected from the group consisting of hydrogen and C1-10 alkyl. The imidazolium-type ionic oligomers lend themselves as soluble/solid supports for biopolymer synthesis.

    摘要翻译： 本公开涉及结构上定义的下式的咪唑鎓型离子低聚物：其中n是1至20的整数; A为N或m为1至5的整数; X选自Br，OTf，CF 3 CO 2，CH 3 CO 2，BF 4，PF 6，NTf 2，F，Cl和I; 并且R选自氢和C 1-10烷基。 咪唑型离子低聚物本身可用作生物聚合物合成的可溶/固体支持体。