公开(公告)号：US4591558A

公开(公告)日：1986-05-27

申请号：US619895

申请日：1984-08-06

Applicant: Kenzo Tamai ,  Isamu Saikawa ,  Takashi Yasuda ,  Shohachi Murakami ,  Toyoo Maeda ,  Hisatsugu Tsuda ,  Hiroshi Sakai ,  Masatoshi Sugita ,  Yoshiko Yamamoto ,  Hisashi Minami ,  Takako Hori

Inventor： Kenzo Tamai ,  Isamu Saikawa ,  Takashi Yasuda ,  Shohachi Murakami ,  Toyoo Maeda ,  Hisatsugu Tsuda ,  Hiroshi Sakai ,  Masatoshi Sugita ,  Yoshiko Yamamoto ,  Hisashi Minami ,  Takako Hori

IPC: C12P1/04 ,  C12P19/26 ,  C12P21/00 ,  C12N1/20 ,  A61K37/00

CPC classification number: C12R1/01 ,  C12P1/04 ,  Y10S435/822

Abstract: Novel TF-2 substances having antitumor and immunostimulating activity, which are obtained from a culture or its supernatant fluid prepared by culturing bacteria belonging to Fusobacterium genus. Said substances are useful for the treatment of cancerous diseases of the mammals including human beings. This disclosure concerns such substances and a process for preparing the same and an antitumor agent containing the same.

Abstract translation: 具有抗肿瘤和免疫刺激活性的新型TF-2物质，其通过培养属于Fusobacterium属的细菌制备的培养物或其上清液获得。 所述物质可用于治疗包括人在内的哺乳动物的癌性疾病。 本公开涉及这些物质及其制备方法和含有该物质的抗肿瘤剂。

公开(公告)号：US4547462A

公开(公告)日：1985-10-15

申请号：US523438

申请日：1983-08-16

Applicant: Kenzo Tamai ,  Isamu Saikawa ,  Takashi Yasuda ,  Shohachi Murakami ,  Toyoo Maeda ,  Hisatsugu Tsuda ,  Hiroshi Sakai ,  Masatoshi Sugita ,  Yoshiko Yamamoto ,  Hisashi Minami ,  Takako Hori

Inventor： Kenzo Tamai ,  Isamu Saikawa ,  Takashi Yasuda ,  Shohachi Murakami ,  Toyoo Maeda ,  Hisatsugu Tsuda ,  Hiroshi Sakai ,  Masatoshi Sugita ,  Yoshiko Yamamoto ,  Hisashi Minami ,  Takako Hori

IPC: C12P1/02 ,  A61K35/74 ,  A61K38/00 ,  A61P35/00 ,  A61P37/04 ,  C07G11/00 ,  C07K14/005 ,  C07K14/195 ,  C07K14/41 ,  C12P1/04 ,  C12P21/00 ,  C12R1/01 ,  C12P19/00

CPC classification number: A61K35/74 ,  C12P1/04 ,  Y10S435/822

Abstract: This invention relates to a process for producing a TF-500 substance having carcinostatic and immunostimulating activities, which comprises subjecting organisms belonging to the Fusobacterium genus to extraction treatment with a dialkyl sulfoxide and obtaining said TF-500 substance from the resulting extract.

Abstract translation: 本发明涉及制备具有制癌和免疫刺激活性的TF-500物质的方法，该方法包括使属于所述Fusobacterium属的生物体用二烷基亚砜进行提取处理，并从所得提取物中获得所述TF-500物质。

公开(公告)号：US4323523A

公开(公告)日：1982-04-06

申请号：US69851

申请日：1979-08-27

Applicant: Setsuo Ueda ,  Takashi Yasuda ,  Tokuyoshi Yamada ,  Shigeki Kobayashi

Inventor： Setsuo Ueda ,  Takashi Yasuda ,  Tokuyoshi Yamada ,  Shigeki Kobayashi

IPC: B01J2/02 ,  B01J2/04 ,  B05B3/10 ,  B22F9/10 ,  C03B19/10 ,  C03B37/05 ,  C04B5/02 ,  D01D5/08

CPC classification number: B05B3/001 ,  B01J2/04 ,  B05B3/1014 ,  B05B3/1064 ,  B22F9/10 ,  C03B19/1015 ,  C03B37/05 ,  C04B14/4675 ,  C21B3/08 ,  B22F2999/00

Abstract: A process disclosed for producing spherical articles or fibers with a specially fixed size from a melt of metal, slag, or flux, by introducing the melt onto the center of a rotating disk through a conduit so as to form a thin film stream of boundary layer on the disk; projecting the thin film stream at a high speed fom the disk periphery into surrounding space to split up the film stream into linear streams; and cooling the linear streams for producing fibers or cooling droplets after further splitting of the each linear stream into droplets for producing spherical particles, with or without parallel or countercurrent gas flow to the linear streams.

Abstract translation: 通过将熔体通过导管引入旋转盘的中心，通过金属，熔渣或助熔剂的熔体制造具有特别固定尺寸的球形制品或纤维的方法，以形成边界层的薄膜流 在磁盘上 将薄膜流以高速的方式投射到周边的周边空间，以将薄膜流分解为线性流; 并且在进一步将每个线性流分解成液滴以产生球形颗粒之后，冷却用于产生纤维或冷却液滴的线性流，具有或不具有平行或逆流气流到线性流。

公开(公告)号：US4129730A

公开(公告)日：1978-12-12

申请号：US759134

申请日：1977-01-13

Applicant: Isamu Saikawa ,  Shuntaro Takano ,  Hiroyuki Imaizumi ,  Isamu Takakura ,  Hirokazu Ochiai ,  Takashi Yasuda ,  Hideo Taki ,  Masaru Tai ,  Yutaka Kodama

Inventor： Isamu Saikawa ,  Shuntaro Takano ,  Hiroyuki Imaizumi ,  Isamu Takakura ,  Hirokazu Ochiai ,  Takashi Yasuda ,  Hideo Taki ,  Masaru Tai ,  Yutaka Kodama

IPC: C07D501/06 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D501/04 ,  C07D501/20 ,  C07D501/22 ,  C07D501/24 ,  C07D501/34 ,  C07D501/36 ,  C07D501/57

CPC classification number: C07D501/57 ,  Y02P20/55

Abstract: Novel 7.alpha.-methoxy-cephalosporins and non-toxic salts thereof, which contain a di-oxo-piperazinylcarbonylamino group in molecule. These compounds are valuable antibacterial compounds for use in mammals including man. This disclosure relates to such compounds.

Abstract translation: 新型7α-甲氧基 - 头孢菌素及其无毒盐，其在分子中含有二 - 氧代 - 哌嗪基羰基氨基。 这些化合物是用于包括人在内的哺乳动物的有价值的抗菌化合物。 本公开涉及这些化合物。

公开(公告)号：US4110327A

公开(公告)日：1978-08-29

申请号：US732860

申请日：1976-10-15

Applicant: Isamu Saikawa ,  Shuntaro Takano ,  Chosaku Yoshida ,  Okuta Takashima ,  Kaishu Momonoi ,  Seietsu Kuroda ,  Miwako Komatsu ,  Takashi Yasuda ,  Yutaka Kodama

Inventor： Isamu Saikawa ,  Shuntaro Takano ,  Chosaku Yoshida ,  Okuta Takashima ,  Kaishu Momonoi ,  Seietsu Kuroda ,  Miwako Komatsu ,  Takashi Yasuda ,  Yutaka Kodama

IPC: C07D499/00 ,  C07D499/64 ,  C07D501/20 ,  C07D241/08 ,  C07D401/12 ,  C07D401/14 ,  C07D413/12

CPC classification number: C07D499/00

Abstract: Novel penicillins and cephalosporins and non-toxic salts thereof, which contain a mono- or di-oxo- or thioxo-piperazino(thio)carbonylamino group in molecule. These compounds are valuable antibacterial compounds for use in mammals including man. This disclosure relates to such compounds and a process for the preparation thereof.

Abstract translation: 新型青霉素和头孢菌素及其无毒盐，其在分子中含有一个或二个氧代或二硫代哌嗪子基（硫代）羰基氨基。 这些化合物是用于包括人在内的哺乳动物的有价值的抗菌化合物。 本公开涉及这些化合物及其制备方法。

公开(公告)号：US08849154B2

公开(公告)日：2014-09-30

申请号：US14136609

申请日：2013-12-20

Applicant: Fran Xu ,  Takashi Yasuda ,  Mitsuru Horinoe

Inventor： Fran Xu ,  Takashi Yasuda ,  Mitsuru Horinoe

IPC: G03G15/08

CPC classification number: G03G15/0898 ,  G03G15/0817 ,  G03G2215/0614

Abstract: A developing device for an image forming apparatus may include a seal and a casing to prevent leakage of developer. In some examples, the seal member may include multiple side surfaces while the casing may include projections that may abut and contact various surfaces of the seal member. According to one arrangement, the casing may include first, second and third protrusions, where each protrusion is configured to abut and contact a corresponding surface of the seal member. Additionally, the second projection may protrude in a position inside of the first projection while the third projection may protrude in a position between the first and second projections.

Abstract translation: 用于图像形成装置的显影装置可以包括密封件和用于防止显影剂泄漏的外壳。 在一些示例中，密封构件可以包括多个侧表面，而壳体可以包括可以邻接和接触密封构件的各个表面的突起。 根据一种布置，壳体可以包括第一，第二和第三突起，其中每个突起被构造成抵靠和接触密封构件的相应表面。 此外，第二突起可以在第一突起内部的位置突出，而第三突起可以在第一和第二突起之间的位置突出。

公开(公告)号：US08320793B2

公开(公告)日：2012-11-27

申请号：US12881483

申请日：2010-09-14

Applicant: Fan Xu ,  Takashi Yasuda ,  Mitsuru Horinoe

Inventor： Fan Xu ,  Takashi Yasuda ,  Mitsuru Horinoe

IPC: G03G15/08

CPC classification number: G03G15/0898 ,  G03G15/0812

Abstract: A development device has a casing configured with a first frame and a second frame. The first frame includes attachment surfaces to which a regulating member is attached. A facing surface of the second frame is disposed between the attachment surfaces, in a predetermined plane including the attachment surfaces, and configured to face a portion of the regulating member between the attachment surfaces. A seal member is disposed between the regulating member and opposite surfaces including the attachment surfaces and the facing surface, and configured to seal first gaps each of which is formed between the facing surface and one of the attachment surfaces, in a first direction parallel to a rotational axis of a developing member rotatably supported by the casing.

Abstract translation: 显影装置具有配置有第一框架和第二框架的壳体。 第一框架包括附接表面，调节构件附接到该附接表面。 第二框架的面对表面设置在包括附接表面的预定平面中的附接表面之间，并且被配置为面对在附接表面之间的调节构件的一部分。 密封构件设置在调节构件和包括附接表面和相对表面的相对表面之间，并且构造成在平行于第一方向的第一方向上密封第一间隙，每个间隙形成在相对表面和一个附接表面之间 由壳体可旋转地支撑的显影部件的旋转轴线。

公开(公告)号：US08301056B2

公开(公告)日：2012-10-30

申请号：US12576685

申请日：2009-10-09

Applicant: Yuichi Matsushita ,  Fan Xu ,  Mitsuru Horinoe ,  Takashi Yasuda

Inventor： Yuichi Matsushita ,  Fan Xu ,  Mitsuru Horinoe ,  Takashi Yasuda

IPC: G03G15/08

CPC classification number: G03G15/0817 ,  G03G15/0884 ,  G03G15/0898

Abstract: A developing device includes a developer carrier which carries a developer, a developing unit housing which rotatably supports the developer carrier, a side seal member which comes into slidable contact with both ends of the developer carrier, a sheet-like elongated seal member which extends in the axial direction of the developer carrier so as to come into slidable contact with the developer carrier, a side seal attachment surface which is formed in the developing unit housing and to which the side seal member is attached, and a support portion which is formed in the developing unit housing and protrudes toward the developer carrier from the side seal attachment surface to support the elongated seal member. The elongated seal member is attached onto the support portion in a state where both ends thereof overlap the side seal member and are opposite the side seal attachment surface. A filler is filled in a gap surrounded by the elongated seal member, the side seal member, the support portion, and the side seal attachment surface. A protrusion for suppressing the spread of the filler is formed at the side seal attachment surface at a predetermined interval from the support portion.

Abstract translation: 显影装置包括承载显影剂的显影剂载体，可旋转地支撑显影剂载体的显影单元壳体，与显影剂载体的两端可滑动接触的侧密封构件，延伸在显影剂载体上的片状细长密封构件 显影剂载体的轴向方向与显影剂载体滑动接触，形成在显影单元壳体中并且安装有侧密封构件的侧密封附接表面和形成在显影剂载体中的支撑部分 显影单元容纳并从侧密封附接表面朝向显影剂载体突出以支撑细长密封构件。 细长密封构件在其两端与侧密封构件重叠并且与侧密封件附接表面相对的状态下附接到支撑部上。 填充物填充在由细长密封构件，侧密封构件，支撑部和侧密封附接表面包围的间隙中。 用于抑制填料扩散的突起形成在侧面密封附着表面上与支撑部分隔开预定间隔。

公开(公告)号：US20100090112A1

公开(公告)日：2010-04-15

申请号：US12444209

申请日：2007-09-13

Applicant: Yoichi Kawada ,  Takashi Yasuda ,  Hironori Takahashi ,  Shinichiro Aoshima

Inventor： Yoichi Kawada ,  Takashi Yasuda ,  Hironori Takahashi ,  Shinichiro Aoshima

IPC: G01N21/35

CPC classification number: G01N21/35 ,  G01N21/23 ,  G01N21/3581

Abstract: A single terahertz wave time-waveform measuring device 1 acquires information on an object to be measured 9 by using a terahertz wave, and includes a light source 11, a beam diameter adjuster 12, a separator 13, a terahertz wave generator 21, a light path length difference adjuster 31, a pulse front tilting unit 32, a polarizer 33, a wave synthesizer 41, an electro-optic crystal 42, an analyzer 43, and a photodetector 44. The terahertz wave generator 21 generates a pulse terahertz wave in response to an input of pump light and outputs the pulse terahertz wave. The pulse front tilting unit 32 makes pulse fronts of the terahertz wave and the probe light when being input into the electro-optic crystal 42 nonparallel to each other by tilting the pulse front of the probe light.

Abstract translation: 单个太赫兹波时间波形测量装置1通过使用太赫兹波获取关于被测量物体9的信息，并且包括光源11，光束直径调节器12，隔膜13，太赫兹波发生器21，光 路径长度差调节器31，脉冲前倾斜单元32，偏振器33，波合成器41，电光晶体42，分析器43和光电检测器44.太赫兹波发生器21响应地产生脉冲太赫兹波 到泵浦光的输入并输出脉冲太赫兹波。 当脉冲前倾斜单元32通过倾斜探测光的脉冲前沿而彼此不平行地输入到电光晶体42中时，使太赫兹波和探测光的脉冲前沿。

公开(公告)号：US07457704B2

公开(公告)日：2008-11-25

申请号：US10893871

申请日：2004-07-20

Applicant: Takashi Yasuda ,  Masami Mikame ,  Hidenobu Suzuki ,  Hiromichi Inayoshi ,  Kensuke Takeuchi

Inventor： Takashi Yasuda ,  Masami Mikame ,  Hidenobu Suzuki ,  Hiromichi Inayoshi ,  Kensuke Takeuchi

IPC: G01C21/30

CPC classification number: G01C21/3658

Abstract: A vehicle navigation apparatus displays an expressway guide diagram indicating the names of plural exits at which a travelling vehicle can exit an expressway and the distance and estimated arrival time to each of the exits. The expressway guide diagram includes a map display for indicating a display of a surrounding-area map of an exit. When the map display is operated, the display scale of the surrounding-area map is determined so as to contain a predetermined number of representative facilities, and the surrounding-area map is displayed on a display device according to the display scale. Therefore, with respect to each exit at which the vehicle can get off the expressway, a map based on the proper display scale corresponding to the positional relationship between each exit and facilities can be displayed.

Abstract translation: 车辆导航装置显示指示行驶车辆能够离开高速公路的多个出口的名称以及到每个出口的距离和估计到达时间的高速公路引导图。 高速公路引导图包括用于指示出口的周围区域地图的显示的地图显示。 当操作地图显示时，确定周围地图的显示比例以包含预定数量的代表性设施，并且根据显示比例显示周围区域图在显示装置上。 因此，关于车辆可以从高速公路下车的各出口，可以显示基于与出口和设施之间的位置关系对应的适当的显示比例的地图。