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公开(公告)号：US08623080B2
公开(公告)日：2014-01-07
申请号：US13240426
申请日：2011-09-22
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61B17/0401 , A61B2017/00243 , A61B2017/0406 , A61B2017/0417 , A61B2017/0496 , A61B2017/0608 , A61F2/2412 , A61F2/2415 , A61F2/2445 , A61F2002/30545 , A61F2220/0016 , A61F2220/0041 , A61F2220/0066 , A61F2220/0075 , A61F2250/001 , Y10S623/91
摘要： A method of using a prosthetic heart valve assembly can include implanting a first prosthesis directly into a native annulus. The first prosthesis can have a central longitudinal axis and a first engagement element. The method can also include engaging the first engagement element of the first prosthesis with a second engagement element of a second prosthesis to securely couple the second prosthesis to the first prosthesis. The second prosthesis can have a prosthetic valve. The first engagement element engages the second engagement element by moving the second prosthesis towards the first prosthesis in a direction generally parallel to the central longitudinal axis until the first engagement element engages the second engagement element.
摘要翻译： 使用假体心脏瓣膜组件的方法可以包括将第一假体直接植入到天然环中。 第一假体可以具有中心纵向轴线和第一接合元件。 该方法还可以包括将第一假体的第一接合元件与第二假体的第二接合元件接合，以将第二假体牢固地连接到第一假体。 第二假体可以具有假体瓣膜。 第一接合元件通过在大致平行于中心纵向轴线的方向上移动第二假体朝向第一假体接合第二接合元件，直到第一接合元件接合第二接合元件。
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公开(公告)号：US20060292206A1
公开(公告)日：2006-12-28
申请号：US10301061
申请日：2002-11-20
申请人： Steven Kim , Brian Shiu , Neil Holmgren
发明人： Steven Kim , Brian Shiu , Neil Holmgren
IPC分类号： A61K9/70
CPC分类号： A61F2/07 , A61B17/12022 , A61B17/12036 , A61B17/12118 , A61B17/12136 , A61B17/12186 , A61B17/1219 , A61B17/12195 , A61B2017/00898 , A61B2017/00986 , A61B2017/1205 , A61B2017/3484 , A61F2/90 , A61F2/954 , A61F2/958 , A61F2002/065 , A61F2002/077 , A61F2002/823 , A61F2250/0003
摘要： The present invention relates to devices and methods for the treatment of diseases in the vasculature, and more specifically, devices and methods for treatment of aneurysms found in blood vessels. In a first embodiment of the present invention, a two part prostheses, where one part is an expandable sponge structure and the other part is an expandable tubular mesh structure, is provided. In the first embodiment, the expandable sponge structure is intended to fill the aneurysm cavity to prevent further dilatation of the vessel wall by creating a buffer or barrier between the pressurized pulsating blood flow and the thinning vessel wall. In the first embodiment, the expandable tubular mesh structure is placed across the aneurysm, contacting the inner wall of healthy vessel proximal and distal to the aneurysm.
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公开(公告)号：US08551162B2
公开(公告)日：2013-10-08
申请号：US10327821
申请日：2002-12-20
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61B17/0401 , A61B2017/00243 , A61B2017/0406 , A61B2017/0417 , A61B2017/0496 , A61B2017/0608 , A61F2/2412 , A61F2/2415 , A61F2/2445 , A61F2002/30545 , A61F2220/0016 , A61F2220/0041 , A61F2220/0066 , A61F2220/0075 , A61F2250/001 , Y10S623/91
摘要： Biologically implantable prostheses and methods of using the same are disclosed. In one embodiment, a heart valve assembly includes a first annular prosthesis sized for introduction into a tissue annulus in a heart; a first magnet in the first prosthesis; a second valve prosthesis separate and disconnected from the first prosthesis and comprising a heart valve crown with leaflets, the second prosthesis configured for introduction into the tissue annulus after introducing the first prosthesis into the tissue annulus; and a second magnet in the second prosthesis, wherein an attraction between the first magnet and the second magnet engages the first prosthesis to the second prosthesis to attach the second prosthesis to the first prosthesis in the tissue annulus.
摘要翻译： 公开了生物可植入假体及其使用方法。 在一个实施例中，心脏瓣膜组件包括尺寸适于引入心脏中的组织环的第一环形假体; 第一假体中的第一磁体; 第二阀门假体与第一假体分离并分离并且包括具有小叶的心脏瓣膜冠，所述第二假体构造成在将第一假体引入组织环之后引入组织环空中; 以及第二假体中的第二磁体，其中第一磁体和第二磁体之间的吸引力将第一假体接合到第二假体以将第二假体附接到组织环中的第一假体。
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公开(公告)号：US20110257737A1
公开(公告)日：2011-10-20
申请号：US13175206
申请日：2011-07-01
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61B17/0401 , A61B2017/00243 , A61B2017/0406 , A61B2017/0417 , A61B2017/0496 , A61B2017/0608 , A61F2/2412 , A61F2/2415 , A61F2/2445 , A61F2002/30545 , A61F2220/0016 , A61F2220/0041 , A61F2220/0066 , A61F2220/0075 , A61F2250/001 , Y10S623/91
摘要： A heart valve assembly includes a first annular prosthesis for implantation within a tissue annulus, a second valve prosthesis, and a plurality of magnets on the first and second prostheses to secure the second prosthesis to the first prosthesis. In one embodiment, the magnets are arranged to allow the second prosthesis to be secured to the first prosthesis in a predetermined angular orientation. During use, the first annular prosthesis is implanted into the annulus, and the second valve prosthesis is inserted into the annulus. The magnets orient the second prosthesis relative to the first prosthesis to align the second prosthesis with the first prosthesis in a predetermined angular orientation; and secure the second prosthesis to the first prosthesis in the predetermined angular orientation.
摘要翻译： 心脏瓣膜组件包括用于植入在组织环空中的第一环形假体，第二瓣膜假体以及在第一和第二假体上的多个磁体，以将第二假体固定到第一假体。 在一个实施例中，磁体被布置成允许第二假体以预定的角度定向固定到第一假体。 在使用期间，将第一环形假体植入到环形空间中，并且将第二瓣膜假体插入到环空中。 所述磁体相对于所述第一假体定向所述第二假体以使所述第二假体与所述第一假体以预定的角度取向对准; 并且以预定的角度定向将第二假体固定到第一假体。
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公开(公告)号：US20070050008A1
公开(公告)日：2007-03-01
申请号：US11552913
申请日：2006-10-25
申请人： Steven Kim , Brian Shiu , Neil Holmgren
发明人： Steven Kim , Brian Shiu , Neil Holmgren
IPC分类号： A61F2/94
CPC分类号： A61F2/07 , A61B17/12022 , A61B17/12036 , A61B17/12118 , A61B17/12136 , A61B17/12186 , A61B17/1219 , A61B17/12195 , A61B2017/00898 , A61B2017/00986 , A61B2017/1205 , A61B2017/3484 , A61F2/90 , A61F2/954 , A61F2/958 , A61F2002/065 , A61F2002/077 , A61F2002/823 , A61F2250/0003
摘要： The present invention relates to devices and methods for the treatment of diseases in the vasculature, and more specifically, devices and methods for treatment of aneurysms found in blood vessels. In a first embodiment of the present invention, a two part prostheses, where one part is an expandable sponge structure and the other part is an expandable tubular mesh structure, is provided. In the first embodiment, the expandable sponge structure is intended to fill the aneurysm cavity to prevent further dilatation of the vessel wall by creating a buffer or barrier between the pressurized pulsating blood flow and the thinning vessel wall. In the first embodiment, the expandable tubular mesh structure is placed across the aneurysm, contacting the inner wall of healthy vessel proximal and distal to the aneurysm.
摘要翻译： 本发明涉及用于治疗脉管系统疾病的装置和方法，更具体地，涉及用于治疗血管中发现的动脉瘤的装置和方法。 在本发明的第一实施例中，提供两部分假体，其中一部分是可膨胀海绵结构，另一部分是可扩张的管状网状结构。 在第一实施例中，可膨胀海绵结构用于填充动脉瘤腔，以通过在加压脉动血流与变薄血管壁之间产生缓冲液或屏障来防止血管壁的进一步扩张。 在第一实施例中，可扩张的管状网状结构横跨动脉瘤放置，与靠近动脉瘤的健康血管的内壁接触。
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公开(公告)号：US06939365B1
公开(公告)日：2005-09-06
申请号：US10379311
申请日：2003-03-03
CPC分类号： A61F2/2409 , A61B17/0401 , A61B2017/00243 , A61B2017/0406 , A61B2017/0417 , A61B2017/0496 , A61B2017/0608 , A61F2/2412 , A61F2/2415 , A61F2/2445 , A61F2002/30545 , A61F2220/0016 , A61F2220/0041 , A61F2220/0066 , A61F2220/0075 , A61F2250/001 , Y10S623/91
摘要： A fixturing assembly is provided that includes a needle and a fixturing device. The needle includes a first sharpened end and a second end including a can. The fixturing device includes an elongate filament having first and second ends, and an enlarged fixturing device on the first end of the filament. The second end of the filament is held by the can by frictional resistance, the second end of the filament being removable from the can when a tensile force is applied between the needle and the second end of the filament that exceeds the frictional resistance. For example, the can may include a coil, corrugations, or a roughened inner surface to removably hold the end of the fixturing device.
摘要翻译： 提供一种包括针和夹持装置的夹持组件。 针包括第一尖端和包括罐的第二端。 该固定装置包括具有第一和第二端部的细长丝，以及在灯丝的第一端上的放大的夹持装置。 细丝的第二端通过摩擦阻力由罐保持，当在针和细丝的第二端之间施加超过摩擦阻力的张力时，灯丝的第二端可从罐脱离。 例如，罐可以包括线圈，波纹或粗糙的内表面，以可拆卸地夹持固定装置的端部。
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公开(公告)号：US08262686B2
公开(公告)日：2012-09-11
申请号：US12340483
申请日：2008-12-19
IPC分类号： A61M29/00
CPC分类号： A61B17/12118 , A61B17/12022 , A61B17/1214 , A61B17/12163 , A61B90/39 , A61B2017/00004 , A61B2017/1205 , A61B2090/3966 , A61F2/07 , A61F2/88 , A61F2/90 , A61F2002/065 , A61F2002/077
摘要： Non-expandable space-occupying devices for treating voids within the body are disclosed. The devices can have multiple non-expandable space-occupying elements connected to a flexible leader. Methods of making and using the devices are also disclosed.
摘要翻译： 公开了一种用于处理体内空隙的不扩张空间占用装置。 设备可以具有连接到柔性引导件的多个不可扩展空间占用元件。 还公开了制造和使用装置的方法。
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18.发明授权公开(公告)号：US07753928B2
公开(公告)日：2010-07-13
申请号：US11105835
申请日：2005-04-14
申请人： Roger de la Torre , J. Stephen Scott , Thomas A. Howell , George D. Hermann , David Shields , Robert T. Chang , Neil Holmgren , David Willis
发明人： Roger de la Torre , J. Stephen Scott , Thomas A. Howell , George D. Hermann , David Shields , Robert T. Chang , Neil Holmgren , David Willis
IPC分类号： A61M29/00
CPC分类号： A61F5/003 , A61B17/12099 , A61B17/12136 , A61B17/12172 , A61B2017/00278 , A61B2017/00292 , A61F5/0036
摘要： A space occupying device for deployment within a patient's stomach and methods of deploying and removing the device. The device includes an expandable member and fasteners, such as sutures, that extend to least partially through the patient's stomach wall, and that anchor the device with the patient's stomach. The device can be deployed and/or removed through transesophageal approaches and/or through a combination of transesophageal and transabdominal approaches.
摘要翻译： 用于在患者胃内部署的空间占用装置以及部署和移除装置的方法。 该装置包括可扩张构件和诸如缝合线的紧固件，其至少部分地延伸通过患者的胃壁，并且将该装置与患者的胃固定在一起。 该装置可以通过食道途径和/或通过经食道和经腹途径的组合来部署和/或移除。
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公开(公告)号：US07074220B2
公开(公告)日：2006-07-11
申请号：US10366535
申请日：2003-02-12
申请人： Bradley Hill , Neil Holmgren , Bruce Modesitt
发明人： Bradley Hill , Neil Holmgren , Bruce Modesitt
IPC分类号： A61B18/18
CPC分类号： A61B17/00008 , A61B18/1492 , A61B2017/00013 , A61B2090/3614
摘要： Veins are removed using a pull catheter introduced over a guidewire which extends between first and second percutaneous access points. Optionally, a side branch management tool including an excision device and/or a viewing scope can be advanced over the same guidewire in the direction opposite to that of the pull catheter. In that way, as the pull catheter inverts the vein being removed, side branches can be selectively viewed and/or severed using the side branch management tool. Arteriovenous fistulas are formed by inverting a length of a vein, mobilizing the inverted length relocating the mobilized end of the vein, and connecting the mobilized end to an artery.
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公开(公告)号：US06602240B2
公开(公告)日：2003-08-05
申请号：US09784871
申请日：2001-02-15
申请人： George D. Hermann , Bradley Hill , Thomas Howell , David Willis , Neil Holmgren , Joshua Whittemore
发明人： George D. Hermann , Bradley Hill , Thomas Howell , David Willis , Neil Holmgren , Joshua Whittemore
IPC分类号： A61M3100
CPC分类号： A61M39/0613 , A61B17/3462 , A61B17/3498 , A61B2017/00469 , A61M39/06 , A61M2039/0633 , A61M2039/066 , A61M2039/0673
摘要： According to the present invention, improved methods and apparatus are provided for regaining hemostasis or otherwise minimizing leakage during endoluminal, surgical or percutaneous intraluminal procedures, and for providing a seal during laparoscopic surgical procedures where there is leakage of the CO2 insufflation, when the primary means of hemostasis or pneumatic CO2 seal is compromised or fails. More particularly the present invention relates to devices having a front hub and a rear hub, one or other of which is adapted to retain a compression seal such that when the front and rear hub are matingly engaged, axial and radial pressure is applied to the compression plug and any devices located therebetween, thereby achieving a seal. The compression device can be applied while a guidewire or additional devices remain within the leaking sheath or trocar, thereby allowing the physician to maintain hemostasis or adequate CO2 insufflation, without exchanging the introducer sheath or laparoscopic port.
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