专利检索 ap:("Valerio Berdini" OR "Robert George Boyle" OR "Gordon Saxty" OR "Marinus Leendert Verdonk" OR "Steven John Woodhead" OR "Paul Graham Wyatt" OR "Hannah Fiona Sore" OR "John Caldwell" OR "Ian Collins" OR "Tatiana Faria Da Fonseca" OR "Alastair Donald") AND inv:"Gordon Saxty" 第 2 页

11.

发明申请
SUBSTITUTED BENZOPYRAZIN DERIVATIVES AS FGFR KINASE INHIBITORS FOR THE TREATMENT OF CANCER DISEASES 有权
标题翻译：作为FGFR激酶抑制剂治疗癌症疾病的替代苯并噻嗪衍生物

公开(公告)号：US20130267525A1

公开(公告)日：2013-10-10

申请号：US13990193

申请日：2011-11-29

申请人： Gordon Saxty , Christopher William Murray , Valerio Berdini , Gilbert Ebai Besong , Christopher Charles Frederick Hamlett , Steven John Woodhead , Yannick Aime Eddy Ligny , Patrick René Angibaud

发明人： Gordon Saxty , Christopher William Murray , Valerio Berdini , Gilbert Ebai Besong , Christopher Charles Frederick Hamlett , Steven John Woodhead , Yannick Aime Eddy Ligny , Patrick René Angibaud

IPC分类号： C07D403/04 , C07D401/14 , C07D403/14

CPC分类号： C07D403/04 , C07D401/14 , C07D403/14

摘要： The invention relates to new quinoxaline derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

摘要翻译： 本发明涉及新的喹喔啉衍生物化合物，包含所述化合物的药物组合物，用于制备所述化合物的方法和所述化合物在治疗疾病中的用途。癌症。

12.

发明授权
Substituted quinoxalines as FGFR kinase inhibitors 有权

公开(公告)号：US09145394B2

公开(公告)日：2015-09-29

申请号：US13990193

申请日：2011-11-29

申请人： Gordon Saxty , Christopher William Murray , Valerio Berdini , Gilbert Ebai Besong , Christopher Charles Frederick Hamlett , Steven John Woodhead , Yannick Aime Eddy Ligny , Patrick René Angibaud

发明人： Gordon Saxty , Christopher William Murray , Valerio Berdini , Gilbert Ebai Besong , Christopher Charles Frederick Hamlett , Steven John Woodhead , Yannick Aime Eddy Ligny , Patrick René Angibaud

IPC分类号： A61K31/498 , C07D241/40 , C07D403/04 , C07D401/14 , C07D403/14

摘要： The invention relates to new quinoxaline derivative compounds of formula (I), to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

13.

发明申请
IMIDAZOPYRIDINE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSINE KINASES 有权
标题翻译：作为受体酪氨酸激酶抑制剂的咪唑吡啶衍生物

公开(公告)号：US20120208791A1

公开(公告)日：2012-08-16

申请号：US12997754

申请日：2009-06-12

申请人： Valerio Berdini , Maria Grazia Carr , Miles Stuart Congreve , Martyn Frederickson , Charlotte Mary Griffiths-Jones , Christopher Charles Frederick Hamlett , Andrew Madin , Christopher William Murray , Rajdeep Kaur Benning , Gordon Saxty , Emma Vickerstaffe , Brian John Williams , Marian Williams , Andrew James Woodhead , Steven John Woodhead , Eddy Jean Edgard Freyne , Tom Cornelis Hortense Govaerts , Patrick René Angibaud

发明人： Valerio Berdini , Maria Grazia Carr , Miles Stuart Congreve , Martyn Frederickson , Charlotte Mary Griffiths-Jones , Christopher Charles Frederick Hamlett , Andrew Madin , Christopher William Murray , Rajdeep Kaur Benning , Gordon Saxty , Emma Vickerstaffe , Brian John Williams , Marian Williams , Andrew James Woodhead , Steven John Woodhead , Eddy Jean Edgard Freyne , Tom Cornelis Hortense Govaerts , Patrick René Angibaud

IPC分类号： A61K31/437 , A61K31/501 , A61P35/00 , C07D513/04 , A61K31/53 , A61K31/506 , C07D471/04 , A61K31/5377

CPC分类号： C07D471/04 , C07D513/04

摘要： The invention relates to new bicyclic heterocyclic derivative compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

摘要翻译： 本发明涉及新的双环杂环衍生物化合物，包含所述化合物的药物组合物和所述化合物在治疗疾病中的用途。癌症。

14.

发明授权
Pyrazolyl quinoxaline kinase inhibitors 有权
标题翻译：吡唑基喹喔啉激酶抑制剂

公开(公告)号：US08895601B2

公开(公告)日：2014-11-25

申请号：US13643741

申请日：2011-04-28

申请人： Gordon Saxty , Christopher William Murray , Valerio Berdini , Gilbert Ebai Besong , Christopher Charles Frederick Hamlett , Christopher Norbert Johnson , Steven John Woodhead , David Charles Rees , Laurence Anne Mevellec , Patrick René Angibaud , Eddy Jean Edgard Freyne , Timothy Pietro Suren Perera , Ronaldus Arnodus Hendrika Joseph Gilissen , Berthold Wroblowski , Jean Fernand Armand Lacrampe , Alexandra Papanikos , Oliver Alexis Georges Querolle , Elisabeth Thérèse Jeanne Pasquier , Isabelle Noëlle Constance Pilatte , Pascal Ghislain André Bonnet , Werner Constant Johan Embrechts , Rhalid Akkari , Lieven Meerpoel

发明人： Gordon Saxty , Christopher William Murray , Valerio Berdini , Gilbert Ebai Besong , Christopher Charles Frederick Hamlett , Christopher Norbert Johnson , Steven John Woodhead , David Charles Rees , Laurence Anne Mevellec , Patrick René Angibaud , Eddy Jean Edgard Freyne , Timothy Pietro Suren Perera , Ronaldus Arnodus Hendrika Joseph Gilissen , Berthold Wroblowski , Jean Fernand Armand Lacrampe , Alexandra Papanikos , Oliver Alexis Georges Querolle , Elisabeth Thérèse Jeanne Pasquier , Isabelle Noëlle Constance Pilatte , Pascal Ghislain André Bonnet , Werner Constant Johan Embrechts , Rhalid Akkari , Lieven Meerpoel

IPC分类号： A61K31/415 , C07D231/10 , C07D231/12 , C07D405/14 , C07D403/04 , C07D487/08 , C07D413/14 , C07D403/14 , C07D409/14

CPC分类号： C07D403/04 , A61K31/498 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D487/08 , C07D491/113 , C07F9/6524

摘要： The invention relates to new quinoxaline derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

摘要翻译： 本发明涉及新的喹喔啉衍生物化合物，包含所述化合物的药物组合物，用于制备所述化合物的方法和所述化合物在治疗疾病中的用途。癌症。

15.

发明申请
PYRAZOLYL QUINAZOLINE KINASE INHIBITORS 有权
标题翻译：吡唑啉喹啉激酶抑制剂

公开(公告)号：US20130072457A1

公开(公告)日：2013-03-21

申请号：US13643741

申请日：2011-04-28

申请人： Gordon Saxty , Christopher William Murray , Valerio Berdini , Gilbert Ebai Besong , Christopher Charles Frederick Hamlett , Christopher Norbert Johnson , Steven John Woodhead , Michael Reader , David Charles Rees , Laurence Anne Mevellec , Patrick René Angibaud , Eddy Jean Edgard Freyne , Tom Cornelis Hortense Govaerts , Johan Erwin Edmond Weerts , Timothy Pietro Suren Perera , Ronaldus Arnodus Hendrika Joseph Gilissen , Berthold Wroblowski , Jean Fernand Armand Lacrampe , Alexandra Papanikos , Oliver Alexis Georges Querolle , Elisabeth Thérèse Jeanne Pasquier , Isabelle Noëlle Constance Pilatte , Pascal Ghislain André Bonnet , Werner Constant Johan Embrechts , Rhalid Akkari , Lieven Meerpoel

发明人： Gordon Saxty , Christopher William Murray , Valerio Berdini , Gilbert Ebai Besong , Christopher Charles Frederick Hamlett , Christopher Norbert Johnson , Steven John Woodhead , Michael Reader , David Charles Rees , Laurence Anne Mevellec , Patrick René Angibaud , Eddy Jean Edgard Freyne , Tom Cornelis Hortense Govaerts , Johan Erwin Edmond Weerts , Timothy Pietro Suren Perera , Ronaldus Arnodus Hendrika Joseph Gilissen , Berthold Wroblowski , Jean Fernand Armand Lacrampe , Alexandra Papanikos , Oliver Alexis Georges Querolle , Elisabeth Thérèse Jeanne Pasquier , Isabelle Noëlle Constance Pilatte , Pascal Ghislain André Bonnet , Werner Constant Johan Embrechts , Rhalid Akkari , Lieven Meerpoel

IPC分类号： C07D403/04 , C07D405/14 , C07D491/113 , C07D401/14 , C07D413/14 , A61K31/5377 , C07D487/08 , C07F9/6558 , A61K31/675 , C07D491/107 , C07D471/04 , C07D403/14 , A61K31/506 , A61P35/00 , A61K31/498

CPC分类号： C07D403/04 , A61K31/498 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D487/08 , C07D491/113 , C07F9/6524

摘要： The invention relates to new quinoxaline derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

摘要翻译： 本发明涉及新的喹喔啉衍生物化合物，包含所述化合物的药物组合物，用于制备所述化合物的方法和所述化合物在治疗疾病中的用途。癌症。

16.

发明授权
Substituted quinoxalines as FGFR kinase inhibitors 有权
标题翻译：取代的喹喔啉作为FGFR激酶抑制剂

公开(公告)号：US09290478B2

公开(公告)日：2016-03-22

申请号：US13990193

申请日：2011-11-29

申请人： Gordon Saxty , Christopher William Murray , Valerio Berdini , Gilbert Ebai Besong , Christopher Charles Frederick Hamlett , Steven John Woodhead , Yannick Aime Eddy Ligny , Patrick René Angibaud

发明人： Gordon Saxty , Christopher William Murray , Valerio Berdini , Gilbert Ebai Besong , Christopher Charles Frederick Hamlett , Steven John Woodhead , Yannick Aime Eddy Ligny , Patrick René Angibaud

IPC分类号： A61K31/498 , C07D241/40 , C07D403/04 , C07D401/14 , C07D403/14

CPC分类号： C07D403/04 , C07D401/14 , C07D403/14

摘要： The invention relates to new quinoxaline derivative compounds of formula (I), to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

摘要翻译： 本发明涉及式（I）的新的喹喔啉衍生物化合物，包含所述化合物的药物组合物，所述化合物的制备方法和所述化合物在治疗疾病中的用途。癌症。

17.

发明授权
Imidazo[1,2-a]pyridine compounds for use in treating cancer 有权
标题翻译：咪唑并[1,2-a]吡啶化合物，用于治疗癌症

公开(公告)号：US08513276B2

公开(公告)日：2013-08-20

申请号：US12520333

申请日：2007-12-21

申请人： Valerio Berdini , Gilbert Ebai Besong , Owen Callaghan , Maria Grazia Carr , Miles Stuart Congreve , Adrian Liam Gill , Charlotte Mary Griffiths-Jones , Andrew Madin , Christopher William Murray , Rajdeep Kaur Nijjar , Michael Alistair O'Brien , Andrew Pike , Gordon Saxty , Richard David Taylor , Emma Vickerstaffe

发明人： Valerio Berdini , Gilbert Ebai Besong , Owen Callaghan , Maria Grazia Carr , Miles Stuart Congreve , Adrian Liam Gill , Charlotte Mary Griffiths-Jones , Andrew Madin , Christopher William Murray , Rajdeep Kaur Nijjar , Michael Alistair O'Brien , Andrew Pike , Gordon Saxty , Richard David Taylor , Emma Vickerstaffe

IPC分类号： C07D471/04 , A61K31/437 , C07D487/04 , A61K31/519 , A61P35/00

CPC分类号： C07D471/04 , C07D487/04

摘要： The invention relates to new bicyclic heterocyclic derivative compounds of Formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer. The compounds of Formula (I) are inhibitors of FGFR, VEGFR or PDGFR.

摘要翻译： 本发明涉及式（I）的新的双环杂环衍生物化合物，包含所述化合物的药物组合物以及所述化合物在治疗疾病中的用途。癌症。式（I）的化合物是FGFR，VEGFR或PDGFR的抑制剂。

18.

发明授权
Bicyclic heterocyclyl derivatives as FGFR kinase inhibitors for therapeutic use 有权
标题翻译：双环杂环基衍生物作为治疗用途的FGFR激酶抑制剂

公开(公告)号：US08481531B2

公开(公告)日：2013-07-09

申请号：US13264593

申请日：2010-04-15

申请人： Gordon Saxty , Valerio Berdini , Eddy Jean Edgard Freyne , Alexandra Papanikos , Pascal Benderitter , Werner Constant Johan Embrechts , Berthold Wroblowski , Rhalid Akkari

发明人： Gordon Saxty , Valerio Berdini , Eddy Jean Edgard Freyne , Alexandra Papanikos , Pascal Benderitter , Werner Constant Johan Embrechts , Berthold Wroblowski , Rhalid Akkari

IPC分类号： A61K31/5377 , A61K31/437 , A61K31/496 , C07D413/02 , C07D471/04 , C07D401/02 , C07D239/20

CPC分类号： C07D471/04

摘要： The invention relates to new bicyclic heterocyclyl derivatives of formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

摘要翻译： 本发明涉及式（I）的新的双环杂环基衍生物，包含所述化合物的药物组合物和所述化合物在治疗疾病中的用途，例如，癌症。