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11.发明申请公开(公告)号：US20180342322A1
公开(公告)日：2018-11-29
申请号：US16039276
申请日：2018-07-18
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid , Rodrigo Ortiz , Catalina Valdivia , Inti Pedroso , Paz Tapia
Abstract: Embodiments of a method and/or system for characterizing one or more appendix-related conditions can include determining a microorganism dataset associated with a set of subjects; and/or performing a characterization process associated with the one or more appendix-related conditions, based on the microorganism dataset, where performing the characterization process can additionally or alternatively include performing an appendix-related characterization process for the one or more appendix-related conditions, and/or determining one or more therapies.
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公开(公告)号：US20180087051A1
公开(公告)日：2018-03-29
申请号：US15717807
申请日：2017-09-27
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid , Audrey Goddard , Rodrigo Ortiz , Sara Bird , Eduardo Morales
IPC: C12N15/10
CPC classification number: C12N15/1082 , C12N15/1089 , Y02A90/26 , C12Q2521/501 , C12Q2525/191 , C12Q2531/113 , C12Q2535/122
Abstract: Embodiments of a method and system for improved microbiome sequencing can include: generating guide RNA complexes for a set of targets corresponding to a set of taxa associated with the microorganism-related condition; processing the biological sample with the gRNA complexes to generate microorganism nucleic acid fragments comprising a set of end regions associated with the set of targets; ligating the set of end regions with a set of adapters sharing an adapter sequence; and amplifying the set of targets based on the ligated set of end regions and a set of primers sharing a primer sequence associated with the adapter sequence.
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13.发明申请公开(公告)号：US20170357762A1
公开(公告)日：2017-12-14
申请号：US15668620
申请日：2017-08-03
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
Abstract: A method for at least one of characterizing, diagnosing, and treating a mental health associated condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the mental health associated condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the mental health associated condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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14.发明申请公开(公告)号：US20170316168A1
公开(公告)日：2017-11-02
申请号：US15645049
申请日：2017-07-10
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid
CPC classification number: G16H50/20 , G06F19/00 , G06F19/3418 , G16B35/00 , G16B40/00 , G16B50/00 , G16C20/60 , G16H40/67 , Y02A90/26
Abstract: A method for at least one of characterizing, diagnosing, and treating an autoimmune disorder in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the autoimmune condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the autoimmune condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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15.发明申请公开(公告)号：US20170316151A1
公开(公告)日：2017-11-02
申请号：US15655468
申请日：2017-07-20
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
CPC classification number: G16B30/00 , C12Q1/689 , C12Q2600/106 , C12Q2600/112 , C12Q2600/16 , G06F19/3418 , G06F19/3456 , G16B5/00 , G16B40/00 , G16B50/00 , G16H20/10 , G16H40/67 , G16H50/20 , Y02A90/26
Abstract: A method for at least one of characterizing, diagnosing, and treating an endocrine system condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the endocrine system condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the endocrine system condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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Patent Agency Ranking
公开(公告)号：US20170270269A1
公开(公告)日：2017-09-21
申请号：US15606874
申请日：2017-05-26
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid
CPC classification number: G06F19/3418 , C12Q1/68 , C12Q1/6883 , C12Q1/689 , C12Q2600/118 , G06F19/00 , G06F19/10 , G06F19/12 , G06F19/28 , G06F19/30 , G16H20/10 , G16H50/20 , Y02A90/26
Abstract: A method for diagnosing and treating an immune microbial dysfunction in a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the immune microbial dysfunction based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset, wherein the characterization is diagnostic of at least one of Crohn's disease, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), ulcerative colitis, and celiac disease; based upon the characterization, generating a therapy model configured to correct the immune microbial dysfunction; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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公开(公告)号：US20170268045A1
公开(公告)日：2017-09-21
申请号：US15606692
申请日：2017-05-26
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid
CPC classification number: C12Q1/689 , C12Q1/6869 , C12Q1/6888 , G06F19/22
Abstract: A method and system for analyzing a microbiome of an individual, comprising: providing a sampling kit to the individual at a location remote from the sample processing network, the sampling kit including a sample container having a lysing component and a sample preservation component and configured to receive a sample from a collection site of the individual; receiving the sample container with the sample from the collection site of the individual; generating a microbiome sequence dataset based upon sequencing nucleic acid content of a microorganism portion of the sample; identifying a set of microorganisms represented in the microorganism portion based upon performance of a mapping operation on portions of the microbiome sequence dataset; generating an analysis based upon a set of features related to the microorganism portion; and transmitting information derived from the analysis to the individual.
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公开(公告)号：US20170175172A1
公开(公告)日：2017-06-22
申请号：US15452529
申请日：2017-03-07
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Catalina Valdivia , Daniel Almonacid , Jessica Richman
CPC classification number: C12Q1/689 , C12Q2600/106 , C12Q2600/112 , C12Q2600/16 , C40B30/02 , G01N33/48792 , G06F19/00 , G06F19/24 , G06F19/28 , G06F19/3418 , G06F19/3481 , G16H50/20 , Y02A90/26
Abstract: Embodiments of a system and method for characterizing a mouth-associated condition in relation to a user can include one or more of: a handling network operable to collect containers including material from a set of users, the handling network including a sequencing system operable to determine microorganism sequences from sequencing the material; a microbiome characterization system operable to determine microbiome composition data and microbiome functional diversity data based on the microorganism sequences, collect supplementary data associated with the mouth-associated condition for the set of users, and transform the supplementary data and features extracted from the microbiome composition data and the microbiome functional diversity data into a characterization model for the mouth-associated condition; and/or a therapy system operable to promote a treatment to the user based on characterizing the user with the characterization model in relation to the mouth-associated condition.
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19.发明申请METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS FOR MENTAL HEALTH ASSOCIATED CONDITIONS 审中-公开用于精神卫生相关条件的微生物衍生诊断和治疗方法与系统公开(公告)号：US20170024527A1
公开(公告)日：2017-01-26
申请号：US15098236
申请日：2016-04-13
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman , Siavosh Rezvan Behbahani
IPC: G06F19/00
Abstract: A method for at least one of characterizing, diagnosing, and treating a mental health associated condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the mental health associated condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the mental health associated condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
Abstract translation: 至少一种在至少一个受试者中表征，诊断和治疗精神卫生相关病症的方法，所述方法包括：从受试者群体接收聚集的一组生物样品; 为受试者群体生成微生物组合数据集和微生物群功能分集数据集中的至少一个; 基于从至少一个微生物组合数据集和微生物组合功能分集数据集提取的特征，产生精神健康相关病症的表征; 基于表征，产生配置用于纠正精神健康相关疾病的治疗模型; 并且在与受试者相关联的输出装置处，基于表征和治疗模型促进对受试者的治疗。
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20.发明申请公开(公告)号：US20160342735A1
公开(公告)日：2016-11-24
申请号：US15207897
申请日：2016-07-12
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman , Siavosh Rezvan Behbahani
CPC classification number: G16B30/00 , C12Q1/689 , C12Q2600/106 , C12Q2600/112 , C12Q2600/16 , G06F19/3418 , G06F19/3456 , G16B5/00 , G16B40/00 , G16B50/00 , G16H20/10 , G16H40/67 , G16H50/20 , Y02A90/26
Abstract: A method for at least one of characterizing, diagnosing, and treating an endocrine system condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the endocrine system condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the endocrine system condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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