Device for improving the purity of a product in a simulated fluid bed
    12.
    发明授权
    Device for improving the purity of a product in a simulated fluid bed 有权
    用于提高模拟流化床中产品纯度的装置

    公开(公告)号:US6110364A

    公开(公告)日:2000-08-29

    申请号:US377645

    申请日:1999-08-19

    IPC分类号: B01D15/18 B01D15/08

    摘要: The device comprises at least one column 1 that is filled with a number of beds A.sub.n having an adsorbent that are separated by a fluid distributor plate P.sub.1. Each plate is divided into a number of sectors P.sub.10 and P.sub.11, and each sector comprises at least one fluid distribution chamber 13 that is pierced with openings and a circulation space 8 in the vicinity of the openings. The chambers of the plate are connected to a line 10 for transfer to the outside. With respect to the chambers on a plate, transfer line 10 P, is connected to another transfer line 20 relative to chambers 23 on another plate (P.sub.i+1 or P.sub.i+2) that is arranged downstream by a bypass line L.sub.1,2. The latter comprises means 14, 15, 16 for monitoring and adjustment of the flow of fluid that circulates there, such that the distribution chambers are flushed by a fluid which has approximately the same composition as that of the fluid that circulates through circulation space 8 at each of the chambers.

    摘要翻译: 该装置包括至少一个填充有多个床的柱1,其具有由流体分配器板P1分离的吸附剂。 每个板被分成多个扇区P10和P11,并且每个扇区包括至少一个在开口附近被开口的流体分配室13和循环空间8。 板的腔室连接到管线10以转移到外部。 相对于板上的室,传输管线10P相对于另一个板(Pi + 1或Pi + 2)上的腔室23连接到另一个传输线20,该另一个板(Pi + 1或Pi + 2)被旁路管线L1,2设置在下游。 后者包括用于监测和调节在那里循环的流体流动的装置14,15,16,使得分配室被流体冲洗,该流体具有与通过循环空间8循环的流体大致相同的组成 每个房间。

    Column with distributor for allowing independent injection and/or
removal of fluids
    13.
    发明授权
    Column with distributor for allowing independent injection and/or removal of fluids 失效
    带分配器的柱,用于独立注入和/或清除流体

    公开(公告)号:US5972214A

    公开(公告)日:1999-10-26

    申请号:US961093

    申请日:1997-10-30

    摘要: The invention is a column for separating a substance from a liquid having a plurality of separable compounds. The column has at least a first and a second bed of granular solids separated by at least one device, the device has at least a collection device which collects the substance to be separated, the collection device being in fluid connection to at least one mixing chamber, at least a first circuit for injection and/or removal of a first secondary fluid B.sub.1 and at least a second injection and/or removal circuit of a second secondary fluid B.sub.2. The injection and/or removal circuits are in communication with the mixing chamber with at least one opening allowing passage of the secondary fluids B.sub.1, B.sub.2 into the mixing chamber. The mixing chamber has at least one inlet orifice and at least one outlet orifice, and a device which redistributes the fluid coming from the mixing chamber, wherein the injection and/or removal circuits are separated and disposed in a vicinity of the mixing chamber along at least one wall of the chamber that has a direction substantially parallel to the device axis.

    摘要翻译: 本发明是用于从具有多个可分离化合物的液体中分离物质的柱。 该柱具有至少一个由至少一个装置隔开的第一和第二颗粒状固体床,所述装置至少具有收集待分离物质的收集装置,所述收集装置与至少一个混合室流体连接 至少一个用于喷射和/或去除第二次流体B1的第一回路和至少第二次流体B2的第二喷射和/或去除回路。 注入和/或去除电路与混合室连通,具有至少一个允许第二流体B1,B2通入混合室的开口。 所述混合室具有至少一个入口孔和至少一个出口孔,以及重新分布来自所述混合室的流体的装置,其中所述注入和/或去除回路在所述混合室附近沿着 室的至少一个壁具有基本上平行于装置轴线的方向。

    Adsorptive separation of 3-hydroxytetrahydrofuran enantiomers
    14.
    发明授权
    Adsorptive separation of 3-hydroxytetrahydrofuran enantiomers 失效
    3-羟基四氢呋喃对映异构体的吸附分离

    公开(公告)号:US5928515A

    公开(公告)日:1999-07-27

    申请号:US990166

    申请日:1997-12-12

    摘要: The chiral isomers of 3-hydroxytetrahyrofuran are separated by means of liquid chromatography using a stationary phase comprising a substituted polysaccharide carbamate. The separation may be performed using a simulated moving bed adsorbent system. Suitable mobile phase materials comprise a mixture of a light paraffin and a low molecular weight aliphatic alcohol such as a mixture of n-hexane and ethanol. Amylose is the preferred polysaccharide.

    摘要翻译: 使用包含取代的多糖氨基甲酸酯的固定相通过液相色谱分离3-羟基四氢呋喃的手性异构体。 可以使用模拟移动床吸附剂系统进行分离。 合适的流动相材料包括轻质石蜡和低分子量脂肪醇如正己烷和乙醇的混合物的混合物。 直链淀粉是优选的多糖。

    Simulated moving bed adsorptive separation process
    16.
    发明授权
    Simulated moving bed adsorptive separation process 失效
    模拟移动床吸附分离过程

    公开(公告)号:US5635072A

    公开(公告)日:1997-06-03

    申请号:US381380

    申请日:1995-01-31

    申请人: Michael G. Moran

    发明人: Michael G. Moran

    IPC分类号: B01D15/18 B01D15/08

    CPC分类号: B01D15/1842 B01D2215/023

    摘要: Various chemicals such as pharmaceuticals and petrochemicals are chromatographically separated in small quantities using an apparatus comprising a number of serially connected adsorbent-containing chambers. The chambers are linked together with valving necessary to simulate the continuous countercurrent flow of the adsorbent and liquid phases. The apparatus employs three three-port valves per chamber to direct liquid flow. Pressure pairing of the valves and the four major process streams protects product purity.

    Small scale simulated moving bed separation process
    17.
    发明授权
    Small scale simulated moving bed separation process 失效
    小型模拟移动床分离过程

    公开(公告)号:US5565104A

    公开(公告)日:1996-10-15

    申请号:US562775

    申请日:1995-11-27

    IPC分类号: B01D15/18 B01D15/08

    CPC分类号: B01D15/1842 B01D2215/023

    摘要: Various chemicals such as pharmaceuticals and petrochemicals are chromatographically separated in pilot plant quantities using an apparatus comprising a number of chambers containing an adsorbent linked together with valving necessary to simulate the continuous countercurrent flow of the adsorbent and liquid phases. The apparatus preferably comprises five multiport rotary valves, each having at least one port for each column. The fifth rotary valve provides a serial interconnection between the columns and also ensures the desired unidirectional flow of fluid in the apparatus.

    摘要翻译: 各种化学品如药物和石油化学品在中试装置中用色谱分离,使用包含多个腔室的装置,该装置包含与模拟连续逆流吸附剂和液相所必需的阀连接在一起的吸附剂。 该装置优选地包括五个多端口旋转阀,每个具有用于每列的至少一个端口。 第五旋转阀在柱之间提供串联连接,并且还确保了设备中期望的单向流体流动。

    Process for separating arabinose from a pentose/hexose mixture
    19.
    发明授权
    Process for separating arabinose from a pentose/hexose mixture 失效
    从戊糖/己糖混合物中分离阿拉伯糖的方法

    公开(公告)号:US4664718A

    公开(公告)日:1987-05-12

    申请号:US904124

    申请日:1986-09-05

    申请人: Chin-Hsiung Chang

    发明人: Chin-Hsiung Chang

    IPC分类号: B01D15/18 C13K13/00

    摘要: A process for the liquid phase adsorptive separation of arabinose from an aqueous feed mixture of monosaccharides containing arabinose along with other aldopentoses and aldohexoses. The feed is contacted with a calcium-Y or clacium-X type zeolite. Arabinose is selectively adsorbed to the substantial exclusion of other aldoses and thereafter is recovered in high purity by desorption with water or ethanol. The process can be carried out on a commercial scale by means of a simulated moving bed flow scheme.

    摘要翻译: 从含有阿拉伯糖的单糖的含水进料混合物与其他戊糖醛酸和己糖醛酸液相吸附分离阿拉伯糖的方法。 进料与钙-Y或沸石-X型沸石接触。 阿拉伯糖被选择性地吸附到其他醛糖的基本排除物上,然后通过用水或乙醇解吸而以高纯度回收。 该过程可以通过模拟移动床流程图在商业规模上进行。

    Method for controlling simulated moving bed system
    20.
    发明授权
    Method for controlling simulated moving bed system 失效
    控制模拟移动床系统的方法

    公开(公告)号:US4599115A

    公开(公告)日:1986-07-08

    申请号:US634006

    申请日:1984-07-24

    摘要: A method is disclosed for controlling a simulated moving bed system of a type including at least four series-arranged beds each packed with a solid adsorbent, with the downstream end of each bed and the upstream end of the next succeeding bed being connected by conduits to form an endless loop, and in which a fluid is caused to circulate through the beds in one direction, a feed stock and a desorbent are introduced into the system while a raffinate and a sorbate are withdrawn from the system, and the positions of introduction and withdrawal of the four kinds of fluid are periodically shifted in the direction of the circulating fluid flow. In accordance with the invention, two or more circulating pumps, provided with variable speed controllers and pressure detectors for detecting the suction pressure of each of the circulating pumps, are disposed between two beds. The flow rates of three of the four fluids introduced into or withdrawn from the system are adjusted to predetermined values, and the flow rate of the other fluid is controlled in such a manner that the suction pressure of one of the circulating pumps or the average of the suction pressures of two or more of the circulating pumps is held constant, and a rotational speed of each of the circulating pumps is controlled independently so as to control the flow rate of the circulating fluid and to maintain the suction pressure of each circulating pump at a low level.

    摘要翻译: 公开了一种用于控制一种类型的模拟移动床系统的方法,其包括每个填充有固体吸附剂的至少四个串联布置的床,每个床的下游端和下一个后续床的上游端通过导管连接到 形成无限循环,并且使流体在一个方向上循环通过床,将原料和解吸剂引入系统中,同时从系统中抽出萃余液和吸附物,并且引入和 四种流体的排出周期性地沿循环流体的流动方向移动。 根据本发明,设置有两个或更多个循环泵,其设置有用于检测每个循环泵的吸入压力的变速控制器和压力检测器,两个床之间。 将引入或取出的四种流体中的三种流体的流量调节到预定值,并且以这样一种方式控制其它流体的流量,使得一种循环泵的吸入压力或平均值 循环泵的两个或更多个的吸入压力保持恒定,并且独立地控制每个循环泵的转速,以便控制循环流体的流量并将每个循环泵的吸入压力保持在 低水平