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公开(公告)号：US20180186751A1
公开(公告)日：2018-07-05
申请号：US15907045
申请日：2018-02-27
Applicant: VERSEON CORPORATION
Inventor： Kevin Michael Short , Son Minh Pham , David Charles Williams
IPC: C07D231/38 , A61K31/5377 , A61K31/4439 , A61K31/4155 , C07D233/88 , C07D409/12 , C07D401/04 , C07D409/14
CPC classification number: C07D231/38 , A61K31/4155 , A61K31/4439 , A61K31/5377 , C07D233/88 , C07D401/04 , C07D409/12 , C07D409/14
Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin, which compounds include substituted pyrazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing a disease or disorder, which disease or disorder is amenable to treatment or prevention by the inhibition of thrombin.
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公开(公告)号：US09957256B2
公开(公告)日：2018-05-01
申请号：US15313343
申请日：2015-05-26
Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
Inventor： Sergii Pazenok , Norbert Lui , Christian Funke
IPC: C07D403/04 , C07D231/16 , C07D231/14 , C07C21/18 , C07D401/14 , C07D231/38
CPC classification number: C07D403/04 , C07C21/18 , C07D231/14 , C07D231/16 , C07D231/38 , C07D401/14
Abstract: A new process for the preparation of 5-fluoro-1H-pyrazoles of the general formula (I) as described herein and further reactions with this compound.
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公开(公告)号：US09956214B2
公开(公告)日：2018-05-01
申请号：US15351525
申请日：2016-11-15
Inventor： Erkang Fan , Wesley C. Van Voorhis , Zhongsheng Zhang , Wenlin Huang , Kayode K. Ojo
IPC: A61K31/4709 , C07D311/20 , C07D231/38 , C07D235/08 , C07D235/12 , C07D487/04 , C07D231/14 , C07D401/04 , C07D401/06 , C07D403/04 , C07D405/04 , C07D405/14 , A61K31/415 , A61K31/4155 , A61K31/416 , A61K31/4184 , A61K31/454 , A61K31/5377
CPC classification number: A61K31/4709 , A61K31/415 , A61K31/4155 , A61K31/416 , A61K31/4184 , A61K31/454 , A61K31/5377 , C07D231/14 , C07D231/38 , C07D235/08 , C07D235/12 , C07D311/20 , C07D401/04 , C07D401/06 , C07D403/04 , C07D405/04 , C07D405/14 , C07D487/04 , Y02A50/488
Abstract: The present disclosure is generally directed to compositions and methods for treating apicomplexan protozoan related disease, such as toxoplasmosis and cryptosporidiosis.
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公开(公告)号：US09932313B2
公开(公告)日：2018-04-03
申请号：US15421729
申请日：2017-02-01
Applicant: Lycera Corporation
Inventor： Gary D. Glick , Alexander R. Hurd , Clarke B. Taylor , Chad A. VanHuis
IPC: A61K31/4439 , A61K31/44 , A61K31/5377 , C07D231/38 , C07D231/40 , C07D401/12 , C07D405/12 , C07D409/04 , C07D409/12 , C07D417/12 , C07D487/14 , C07D401/14 , C07D413/12 , C07D413/14 , C07D403/12
CPC classification number: C07D231/38 , A61K31/44 , A61K31/4439 , A61K31/5377 , C07D231/40 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/04 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D487/14
Abstract: The invention provides pyrazolyl guanidine compounds that inhibit F1Fo-ATPase, and methods of using pyrazolyl guanidine compounds as therapeutic agents to treat medical disorders, such as an immune disorder, inflammatory condition, or cancer.
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公开(公告)号：US20180086748A1
公开(公告)日：2018-03-29
申请号：US15814927
申请日：2017-11-16
Applicant: Boehringer Ingelheim International GmbH
Inventor： Joerg BENTZIEN , Angela Kay BERRY , Todd BOSANAC , Michael Jason BURKE , Darren Todd DISALVO , Joshua Courtney HORAN , Shuang LIANG , Can MAO , Wang MAO , Yue SHEN , Fariba SOLEYMANZADEH , Renee M. ZINDELL
IPC: C07D417/08 , C07D417/06 , C07D231/14 , C07D417/02 , C07D413/14 , C07D405/14 , C07D403/08 , C07D403/06 , C07D403/04 , C07D401/14 , C07D401/06 , C07D401/04 , C07D401/02 , C07D277/56 , C07D231/40 , C07D231/38 , C07D417/04
CPC classification number: C07D417/08 , C07D231/14 , C07D231/38 , C07D231/40 , C07D277/56 , C07D401/02 , C07D401/04 , C07D401/06 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/08 , C07D405/14 , C07D413/14 , C07D417/02 , C07D417/04 , C07D417/06
Abstract: The present invention encompasses compounds of the formula (I) wherein the groups A, Cy, X1 and Y are defined herein, which are suitable for the treatment of diseases related to BTK, process of making, pharmaceutical preparations which contain compounds and their methods of use.
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Patent Agency Ranking
公开(公告)号：US09908864B2
公开(公告)日：2018-03-06
申请号：US15583122
申请日：2017-05-01
Applicant: Dow AgroSciences LLC
Inventor： Qiang Yang , Beth Lorsbach , Greg Whiteker , Carl DeAmicis , Kaitlyn Gray , Yu Zhang , Joseck M. Muhuhi
IPC: A01N43/56 , C07D401/04
CPC classification number: C07D401/04 , A01N43/56 , C07D231/38 , C07D231/40 , C07D401/14
Abstract: The present application provides processes for making pesticidal compounds and compounds useful both as pesticides and in the making of pesticidal compounds.
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公开(公告)号：US20180016247A1
公开(公告)日：2018-01-18
申请号：US15716905
申请日：2017-09-27
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Jagabandhu Das , Ramesh Padmanabha , Ping Chen , Derek J. Norris , Arthur M.P. Doweyko , Joel C. Barrish , John Wityak
IPC: C07D277/56 , C07D471/04 , C07D417/14 , C07D417/12 , C07D417/06 , C07D409/12 , C07C233/65 , C07D239/42 , C07D233/90 , C07D231/38 , C07D213/82 , C07D213/81 , C07C237/40 , C07D263/48 , C07D491/113
CPC classification number: C07D277/56 , C07C233/65 , C07C237/40 , C07D213/81 , C07D213/82 , C07D231/38 , C07D233/90 , C07D239/42 , C07D263/48 , C07D409/12 , C07D417/06 , C07D417/12 , C07D417/14 , C07D471/04 , C07D491/113
Abstract: Novel cyclic compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of protein tyrosine kinase-associated disorders such as immunologic and oncologic disorders.
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公开(公告)号：US09815791B2
公开(公告)日：2017-11-14
申请号：US15101129
申请日：2014-12-10
Applicant: Lycera Corporation
Inventor： Donald J. Skalitzky , Chad A. VanHuis
IPC: C07D231/38 , A61K31/415
CPC classification number: C07D231/38
Abstract: The invention provides pyrazolyl guanidine compounds that inhibit F1Fo-ATPase, and methods of using pyrazolyl guanidine compounds as therapeutic agents to treat medical disorders, such as an immune disorder, inflammatory condition, or cancer.
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公开(公告)号：US20170320867A1
公开(公告)日：2017-11-09
申请号：US15661644
申请日：2017-07-27
Applicant: Boehringer Ingelheim International GmbH
Inventor： Joerg Martin BENTZIEN , Angela Kay BERRY , Todd BOSANAC , Michael Jason BURKE , Darren Todd DISALVO , Joshua Courtney HORAN , Shuang LIANG , Can MAO , Wang MAO , Yue SHEN , Fariba SOLEYMANZADEH , Renee M. ZINDELL
IPC: C07D417/08 , C07D231/14 , C07D417/02 , C07D413/14 , C07D405/14 , C07D403/08 , C07D403/06 , C07D403/04 , C07D401/14 , C07D401/06 , C07D401/04 , C07D401/02 , C07D277/56 , C07D231/40 , C07D231/38 , C07D417/04 , C07D417/06
CPC classification number: C07D417/08 , C07D231/14 , C07D231/38 , C07D231/40 , C07D277/56 , C07D401/02 , C07D401/04 , C07D401/06 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/08 , C07D405/14 , C07D413/14 , C07D417/02 , C07D417/04 , C07D417/06
Abstract: The present invention encompasses compounds of the formula (I) wherein the groups A, Cy, X1 and Y are defined herein, which are suitable for the treatment of diseases related to BTK, process of making, pharmaceutical preparations which contain compounds and their methods of use.
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公开(公告)号：US09796682B2
公开(公告)日：2017-10-24
申请号：US15370524
申请日：2016-12-06
Applicant: Dow AgroSciences LLC
Inventor： Qiang Yang , Beth Lorsbach , Gregory Whiteker , Gary Roth , Carl DeAmicis , Thomas Clark , Kaitlyn Gray , Belgin Canturk , Elisabeth J. Kane , Yu Zhang , Joseck M. Muhuhi
IPC: C07D401/04 , C07D231/38 , C07D231/40 , A01N43/56 , C07C321/14 , C07C321/16
CPC classification number: C07D231/38 , A01N43/56 , C07C321/14 , C07C321/16 , C07C2601/02 , C07D231/40 , C07D401/04
Abstract: The present application provides processes for making pesticidal compounds and compounds useful both as pesticides and in the making of pesticidal compounds.
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