PLASMONIC INTERFEROMETER SENSOR
    13.
    发明申请
    PLASMONIC INTERFEROMETER SENSOR 有权
    等离子干扰仪传感器

    公开(公告)号:US20160187256A1

    公开(公告)日:2016-06-30

    申请号:US15064738

    申请日:2016-03-09

    申请人: Lehigh University

    IPC分类号: G01N21/45 G01N21/552

    摘要: An optical device includes a transparent substrate and a conductive layer disposed over an upper surface of the transparent substrate. The conductive layer defines at least one groove inwardly extending from an upper surface and includes an aperture that is spaced apart from the at least one groove. An interface between the upper surface of the conductive layer and an ambient medium defines an optical branch along which surface plasmon polariton modes are excited in response to at least partially coherent light being received by the optical device.

    摘要翻译: 光学装置包括透明基板和设置在透明基板的上表面上的导电层。 导电层限定从上表面向内延伸的至少一个凹槽,并且包括与所述至少一个凹槽间隔开的孔。 导电层的上表面和环境介质之间的界面限定了光学分支,响应于由光学装置接收的至少部分相干的光,表面等离子体激元模式被激发。

    METHOD FOR SENSOR CALIBRATION
    15.
    发明申请
    METHOD FOR SENSOR CALIBRATION 审中-公开
    传感器校准方法

    公开(公告)号:US20140350868A1

    公开(公告)日:2014-11-27

    申请号:US14359606

    申请日:2012-11-13

    申请人: EPISENTEC AB

    发明人: Anders Hanning

    IPC分类号: G01N21/59

    摘要: The present invention provides a method of determining the amount of an optical probe species binding to or releasing from an optical sensor surface characterized in that the determination comprises the steps of: a) determining, at one single wavelength or at more than one wavelength, a physical measurand (xi) that is related to the absorptivity of said probe, b) correlating the value of the measurand to the amount of said optical probe species binding to or releasing from said surface, respectively, wherein the physical measurand (xi) of step a) is a physical measurand in which the contribution from the refractive index is substantially zero. The present invention further provides different uses of a peak width as well as a computer program product and reagent kits for the disclosed methods.

    摘要翻译: 本发明提供一种确定与光学传感器表面结合或从光学传感器表面释放的光学探针物质的量的方法,其特征在于,所述测定包括以下步骤:a)在单个波长或多于一个波长处确定 与所述探针的吸收性相关的物理测量(xi),b)分别将所述被测量的值与所述光学探针物质与所述表面结合或释放的量相关联,其中所述步骤的物理测量(xi) a)是物理测量,其中折射率的贡献基本为零。 本发明进一步提供峰宽度的不同用途以及用于所公开方法的计算机程序产品和试剂盒。

    SPR Sensor Cell and SPR Sensor
    18.
    发明申请
    SPR Sensor Cell and SPR Sensor 有权
    SPR传感器单元和SPR传感器

    公开(公告)号:US20150260649A1

    公开(公告)日:2015-09-17

    申请号:US14426376

    申请日:2013-08-30

    IPC分类号: G01N21/552 G02B6/10

    摘要: There are provided an SPR sensor cell and sensor, both having very excellent detection sensitivity. The SPR sensor cell includes: an under-cladding layer; a core layer, at least a part of the core layer being adjacent to the under-cladding layer; and a metal layer covering the core layer. The core layer includes a uniform layer and a gradient layer arranged between the uniform layer and the under-cladding layer; a refractive index NCO of the uniform layer satisfies a relationship of 1.34≦NCO

    摘要翻译: 提供了具有非常优异的检测灵敏度的SPR传感器单元和传感器。 SPR传感器单元包括:下敷层; 芯层,芯层的至少一部分与下敷层相邻; 以及覆盖芯层的金属层。 芯层包括均匀层和布置在均匀层和下敷层之间的梯度层; 均匀层的折射率NCO满足1.34&nlE; NCO <1.44的关系; 下层包层的折射率NCL和均匀层的折射率NCO满足NCO-NCL≥0.020的关系; 并且梯度层的折射率在大于NCL至小于NCO的范围内,在梯度层的厚度方向上从下敷层侧向均匀层侧逐渐增大。

    LABEL-FREE SENSING CHIP AND APPLICATION THEREOF
    19.
    发明申请
    LABEL-FREE SENSING CHIP AND APPLICATION THEREOF 审中-公开
    无标签传感芯片及其应用

    公开(公告)号:US20150080253A1

    公开(公告)日:2015-03-19

    申请号:US14476191

    申请日:2014-09-03

    申请人: Academia Sinica

    IPC分类号: G01N21/59 G01N21/21

    CPC分类号: G01N21/59 G01N2021/5903

    摘要: The present invention provides a label-free sensing chip for identifying a chemical substance, comprising: (a) a transparent substrate comprising a base and first periodic ridges; and (b) a metal layer covering said transparent substrate, comprising second periodic ridges and third periodic ridges, in which said second periodic ridges has a height equal to or greater than the height of the first periodic ridges, and each ridge of the second periodic ridges fits into the space between each ridge of the first periodic ridges, and said third periodic ridges correspondingly located on said first periodic ridges. The present invention also provides a method for identifying a chemical substance by using the foresaid label-free sensing chip.

    摘要翻译: 本发明提供了一种用于识别化学物质的无标签感测芯片,包括:(a)包括基底和第一周期性脊的透明基底; 和(b)覆盖所述透明衬底的金属层,包括第二周期性脊和第三周期性脊,其中所述第二周期性脊具有等于或大于第一周期性脊的高度的高度,以及第二周期性脊的每个脊 脊部装配到第一周期性脊脊的每个脊之间的空间中,并且所述第三周期性脊相应地位于所述第一周期性脊上。 本发明还提供了一种通过使用上述无标记感测芯片来鉴别化学物质的方法。

    SURFACE PLASMON-BASED NANOSENSORS AND SYSTEMS AND METHODS FOR SENSING PHOTONS AND CHEMICAL OR BIOLOGICAL AGENTS
    20.
    发明申请
    SURFACE PLASMON-BASED NANOSENSORS AND SYSTEMS AND METHODS FOR SENSING PHOTONS AND CHEMICAL OR BIOLOGICAL AGENTS 审中-公开
    基于表面等离子体的纳米传感器和系统以及用于感测光子和化学或生物学代理的方法

    公开(公告)号:US20140285809A1

    公开(公告)日:2014-09-25

    申请号:US14168051

    申请日:2014-01-30

    发明人: Thalal GHANNAM

    IPC分类号: G01N21/55

    摘要: Surface plasmon-based nanosensor, comprising: at least one first element of metal, preferably silver or gold, or of semiconductor, the first element being excitable to surface Plasmon resonance, in particular localized surface plasmon resonance, in the presence of electromagnetic radiation from a source, and at least one second element preferably near the first element that in the presence of the electromagnetic radiation is exciton-plasmon coupled to the first element and emits electromagnetic radiation representative of the exciton-plasmon coupling, and systems and methods for sensing photons and chemical or biological agents.

    摘要翻译: 表面等离子体激元型纳米传感器,包括:金属,优选银或金或半导体的至少一个第一元素,第一元素可激发表面等离子体共振,特别是局部表面等离子体共振,在来自 源和至少一个第二元件,优选地在第一元件附近,在存在电磁辐射的情况下是激子等离子体激元耦合到第一元件并且发射表示激子等离子体耦合的电磁辐射,以及用于感测光子的系统和方法,以及 化学或生物制剂。