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    SPR sensor cell and SPR sensor
    6.
    发明授权
    SPR sensor cell and SPR sensor 有权
    SPR传感器单元和SPR传感器

    公开(公告)号：US09535003B2

    公开(公告)日：2017-01-03

    申请号：US14426376

    申请日：2013-08-30

    Applicant: NITTO DENKO CORPORATION

    Inventor： Hajime Nishio ,  Tomohiro Kontani

    IPC: G01N21/552 ,  G01N21/03 ,  G02B6/10 ,  G02B6/122 ,  G02B6/138 ,  G01N21/59 ,  G02B1/04 ,  G02B6/12

    CPC classification number: G01N21/553 ,  G01N21/03 ,  G01N2021/5903 ,  G01N2201/088 ,  G02B1/04 ,  G02B6/10 ,  G02B6/1226 ,  G02B6/138 ,  G02B2006/12095 ,  C08L27/12

    Abstract: There are provided an SPR sensor cell and sensor, both having very excellent detection sensitivity. The SPR sensor cell includes: an under-cladding layer; a core layer, at least a part of the core layer being adjacent to the under-cladding layer; and a metal layer covering the core layer. The core layer includes a uniform layer and a gradient layer arranged between the uniform layer and the under-cladding layer; a refractive index NCO of the uniform layer satisfies a relationship of 1.34≦NCO

    Abstract translation: 提供了具有非常优异的检测灵敏度的SPR传感器单元和传感器。 SPR传感器单元包括：下敷层; 芯层，芯层的至少一部分与下敷层相邻; 以及覆盖芯层的金属层。 芯层包括均匀层和布置在均匀层和下敷层之间的梯度层; 均匀层的折射率NCO满足1.34≤NCO<1.44的关系; 下层包层的折射率NCL和均匀层的折射率NCO满足NCO-NCL≥0.020的关系; 并且梯度层的折射率在大于NCL至小于NCO的范围内，在梯度层的厚度方向上从下敷层侧向均匀层侧逐渐增大。

    FLUID DETECTOR AND COUPLER THEREOF
    7.
    发明申请
    FLUID DETECTOR AND COUPLER THEREOF 审中-公开
    流体检测器及其耦合器

    公开(公告)号：US20160377537A1

    公开(公告)日：2016-12-29

    申请号：US14752285

    申请日：2015-06-26

    Applicant: NATIONAL SUN YAT-SEN UNIVERSITY

    Inventor： Jau-Sheng WANG ,  Steve LAO ,  Chang-Wei HO ,  Jia-Ching CHEN ,  Tai-De LIU

    IPC: G01N21/41

    CPC classification number: G01N21/4133 ,  G01N2201/088

    Abstract: A fluid detector includes a coupler. The coupler includes a hollow tube, an optical fiber, and a jacket. A fluid delivery device includes a fluid output end and a fluid recovery end. The fluid output end is connected to a first input end of the hollow tube. The fluid recovery end is connected to a first output end of the hollow tube. An optical signal generator inputs an optical signal to a second input end of the optical fiber. A detection module includes an optical sensor, a database, and a processor. The optical sensor detects the optical signal outputted by the second output end and generates a sensing datum. The processor is electrically connected to the optical sensor and the database. The processor compares a characteristic value of the sensing datum with characteristic values of sample data stored in the database and generates a detection data.

    Abstract translation: 流体检测器包括耦合器。 耦合器包括中空管，光纤和护套。 流体输送装置包括流体输出端和流体回收端。 流体输出端连接到中空管的第一输入端。 流体回收端连接到中空管的第一输出端。 光信号发生器将光信号输入到光纤的第二输入端。 检测模块包括光学传感器，数据库和处理器。 光学传感器检测由第二输出端输出的光信号，并产生检测数据。 处理器电连接到光学传感器和数据库。 处理器将感测数据的特征值与存储在数据库中的样本数据的特征值进行比较，并生成检测数据。

    Frequency Domain Discrimination Of Tissue Proteins
    9.
    发明申请
    Frequency Domain Discrimination Of Tissue Proteins 审中-公开
    组织蛋白质的频域鉴别

    公开(公告)号：US20160266087A1

    公开(公告)日：2016-09-15

    申请号：US15064985

    申请日：2016-03-09

    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN

    Inventor： Joe Fu-Jiou LO ,  Zhengtuo ZHAO ,  Rui LIU

    IPC: G01N33/483 ,  G01N21/64

    CPC classification number: G01N33/4833 ,  A61B3/00 ,  A61B3/10 ,  A61B5/00 ,  A61B5/0066 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/443 ,  G01N21/6408 ,  G01N21/6486 ,  G01N2021/6463 ,  G01N2021/6484 ,  G01N2201/062 ,  G01N2201/088 ,  G01N2333/78

    Abstract: Devices and methods for performing frequency domain (FD) fluorescence lifetime spectroscopy are provided. The devices include a modulated light source, a focusing optical fiber, a detecting optical fiber, and a detector. The methods include focusing sinusoidal modulated incident light from a light source on a biological sample containing a protein, detecting a range of wavelengths of sinusoidal modulated fluorescent light emitted from the protein, determining a phase shift for the modulated fluorescent light, determining an amplitude modulation of the modulated fluorescent light, and determining a fluorescence lifetime of the protein.

    Abstract translation: 提供了用于执行频域（FD）荧光寿命光谱的装置和方法。 该装置包括调制光源，聚焦光纤，检测光纤和检测器。 所述方法包括将来自光源的正弦调制入射光聚焦在含有蛋白质的生物样品上，检测从蛋白质发射的正弦调制荧光的波长范围，确定调制荧光的相移，确定调制荧光的幅度调制 调制荧光，并测定蛋白质的荧光寿命。

    MEASUREMENT METHOD BASED ON AN OPTICAL WAVEGUIDE SENSOR SYSTEM
    10.
    发明申请
    MEASUREMENT METHOD BASED ON AN OPTICAL WAVEGUIDE SENSOR SYSTEM 审中-公开
    基于光波导传感器系统的测量方法

    公开(公告)号：US20160146729A1

    公开(公告)日：2016-05-26

    申请号：US14897790

    申请日：2014-06-05

    Applicant: CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Développement

    Inventor： Florian Kehl ,  Stéphane Follonier

    IPC: G01N21/41

    CPC classification number: G01N21/41 ,  G01N21/276 ,  G01N21/553 ,  G01N21/7743 ,  G01N2201/088

    Abstract: A method for measuring a value change of a parameter at the sensing area of an optical sensor element. The method includes the steps:changing the value of the parameter thereby detecting the position and position change of a first signal peak within the detection window of a detector as well as thereby detecting the position and the eventual position change of a second signal peak within the detection window of the detector, and correlating the position detections of first and second signal peak and correlating the position change detections of first and second signal peak and attributing a value and/or a value change to the correlated detections

    Abstract translation: 一种用于测量光学传感器元件的感测区域处的参数的值变化的方法。 该方法包括以下步骤：改变参数的值，从而检测检测器的检测窗口内的第一信号峰值的位置和位置变化，从而检测在检测器的检测窗口内的第二信号峰值的位置和最终位置变化 检测器的检测窗口，并且对第一和第二信号峰值的位置检测进行相关，并且将第一和第二信号峰值的位置变化检测与归一化值和/或值变化相关联到相关检测

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