公开(公告)号：US12060275B2

公开(公告)日：2024-08-13

申请号：US16437725

申请日：2019-06-11

申请人： Lehigh University

发明人： John T. Fox ,  Kun Yang

IPC分类号： C01B32/984 ,  B01D39/20 ,  B01D46/24 ,  B01J27/053 ,  C04B35/573 ,  C04B35/622 ,  C04B35/65

CPC分类号： C01B32/984 ,  B01D39/2068 ,  B01D39/2082 ,  B01D46/2425 ,  B01D46/2429 ,  B01D46/24491 ,  B01D46/2451 ,  B01D46/2482 ,  B01J27/053 ,  C04B35/573 ,  C04B35/62281 ,  C04B35/65 ,  B01D2239/025 ,  B01D2239/10 ,  B01D2239/1208 ,  B01D2239/1291 ,  C01P2002/72 ,  C01P2002/85 ,  C01P2004/03 ,  C01P2004/20 ,  C01P2006/10 ,  C04B2235/3826 ,  C04B2235/602 ,  C04B2235/656 ,  C04B2235/77

摘要： A method of making SiC nanowires comprising: (a) mixing silicon powder with a carbon-containing biopolymer and a catalyst at room temperature to form a mixture; and (b) heating said mixture to a pyrolyzing temperature sufficient to react said biopolymer and said silicon power to form SiC nanowires.

公开(公告)号：US20230370124A1

公开(公告)日：2023-11-16

申请号：US17745019

申请日：2022-05-16

申请人： Lehigh University

发明人： Yahong Rosa Zheng ,  Xiyuan Zhu

IPC分类号： H04B7/0413 ,  H04L27/20

CPC分类号： H04B7/0413 ,  H04L27/20

摘要： An acoustic transmission device may communicate sensing data via one or more multiple-input multiple-output (MIMO) transmissions. The device may comprise a serial peripheral interface (SPI) and/or a phase shifting key (PSK) modulator. The device may be configured to provide a first SPI signal, perhaps including one or more coded information bits, to the PSK modulator. The device may provide a second SPI signal, perhaps including a synchronous clock signal, to the PSK modulator. The device may generate of one or more symbols on N transmit branches based on the first SPI signal. The device may generate of at least one carrier frequency with one or more phases to form one or more phased carriers based on the second SPI signal. The device may control a transmission of the sensing data (e.g., video) via the one or more symbols on the N transmit branches on the one or more phased carriers.

公开(公告)号：US11731991B2

公开(公告)日：2023-08-22

申请号：US16991440

申请日：2020-08-12

申请人： Rutgers, The State University of New Jersey ,  Lehigh University

发明人： Jeffrey D. Laskin ,  Diane E. Heck ,  Carl J. Lacey ,  Ned D. Heindel ,  Sherri C. Young

IPC分类号： C07F7/08 ,  A61K31/405 ,  A61K31/196 ,  A61K31/19 ,  A61K47/55 ,  A61K9/00 ,  A61K31/192 ,  C07C69/96 ,  C07C229/42 ,  C07D209/28 ,  A61K47/54

CPC分类号： C07F7/0812 ,  A61K9/0014 ,  A61K31/19 ,  A61K31/192 ,  A61K31/196 ,  A61K31/405 ,  A61K47/54 ,  A61K47/55 ,  C07C69/96 ,  C07C229/42 ,  C07D209/28 ,  C07F7/081 ,  C07C2602/10

摘要： Augmented or synergized anti-inflammatory constructs are disclosed including anti-inflammatory terpenes and/or vanilloids covalently conjugated to one another so that the activity of the conjugate is greater than the sum of its parts. Also disclosed are methods of improving the potency of an anti-inflammatory terpene or vanilloid by linking it to another anti-inflammatory terpene or vanilloid via a carbamate linkage, where the potency of the conjugate is greater than the sum of its parts.

公开(公告)号：US11554533B2

公开(公告)日：2023-01-17

申请号：US16610666

申请日：2018-05-04

申请人： Lehigh University

发明人： John P. Coulter

IPC分类号： B29C64/118 ,  B29C64/321 ,  B29C64/364 ,  B29C64/245 ,  B29C64/295 ,  B29C64/209 ,  B29C64/241 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y40/00

摘要： Described herein are additive manufacturing systems and methods for printing 3D objects.

公开(公告)号：US20200206384A1

公开(公告)日：2020-07-02

申请号：US16632992

申请日：2018-07-23

申请人： Lehigh University

发明人： Lesley W. CHOW ,  Hannah L. DAILEY

IPC分类号： A61L27/18 ,  A61L27/58 ,  A61L27/54 ,  B33Y70/00 ,  B33Y80/00 ,  B33Y10/00 ,  B29C64/106

摘要： Described herein is a 3D-printed scaffold comprising a peptide-polymer conjugate, the peptide-polymer conjugate having the structure: X-Y-Z-Y-X, wherein X is a biologically active peptide, Y is a linker moiety, and Z is a biocompatible and biodegradable polymer.

公开(公告)号：US10570161B2

公开(公告)日：2020-02-25

申请号：US15365088

申请日：2016-11-30

申请人： Rutgers, The State University of New Jersey ,  Lehigh University

发明人： Jeffrey D. Laskin ,  Diane E. Heck ,  Mou-Tuan Huang ,  Karine Fabio ,  Carl J. Lacey ,  Sherri C. Young ,  Pramod Mohanta ,  Christophe Guillon ,  Ned D. Heindel

IPC分类号： C07F7/08 ,  A61K31/405 ,  A61K31/196 ,  A61K31/19 ,  A61K47/55 ,  A61K47/54 ,  A61K9/00 ,  A61K31/192 ,  C07C69/96 ,  C07C229/42 ,  C07C209/28 ,  C07D209/28

摘要： A new family of therapeutics which provides a controlled-release delivery platform for non-steroidal anti-inflammatory agents on an ester or an ester-carbonate backbone is disclosed herein. These agents are reversible inhibitors of acetylcholinesterase and are thus useful for clinical conditions benefiting from inflammation suppression and cholinergic intervention. These compounds are of the general formula wherein n=0, 1; X=C, Si, and N+ and NSAID=ibuprofen, naproxen, indomethacin and diclofenac. Other embodiments are also disclosed.

公开(公告)号：US10376885B2

公开(公告)日：2019-08-13

申请号：US15343784

申请日：2016-11-04

申请人： Lehigh University

发明人： Xuanhong Cheng ,  Chao Zhao ,  Alparslan Oztekin

IPC分类号： B01L3/00 ,  B01L7/00 ,  B01F5/00

摘要： Disclosed herein are apparatuses comprising, for example, a microfluidic channel device comprising a main body comprising a channel configured to provide for helical fluid motion of material within the channel; and a temperature control system that applies a temperature gradient to the channel. Methods of making and using the apparatus are also described.

公开(公告)号：US20190079320A1

公开(公告)日：2019-03-14

申请号：US16190728

申请日：2018-11-14

申请人： Lehigh University

发明人： Himanshu Jain ,  Volkmar Dierolf ,  Keith J. Veenhuizen

IPC分类号： G02F1/00 ,  G02F1/035 ,  G02B6/13 ,  G02B6/122 ,  G02B6/12

CPC分类号： G02F1/0018 ,  G02B6/122 ,  G02B6/13 ,  G02B2006/12095 ,  G02F1/035 ,  G02F2202/20 ,  G02F2203/07

摘要： In one aspect the invention provides a graded refractive index single crystal waveguide having a glass block containing at least one crystal core, the crystal core having a central portion extending along an axis from a first end to a second end; an interface defining a peripheral boundary of the crystal core at a junction of the crystal core and an adjacent portion of the glass block, and a continuous, radially symmetric misorientation transverse to the central portion; wherein the misorientation has a misorientation angle that increases with increasing distance from the central portion towards the interface.

公开(公告)号：US10125033B2

公开(公告)日：2018-11-13

申请号：US14883229

申请日：2015-10-14

申请人： Lehigh University

发明人： Arup K. Sengupta ,  Michael German ,  Jinze Li

IPC分类号： C02F1/42 ,  C02F5/02 ,  B01D15/36 ,  B01J41/14 ,  C02F9/00 ,  C02F101/10 ,  C02F103/10 ,  C02F101/00 ,  C02F101/20

摘要： The present invention includes an anion exchange method that uses sulfate-containing acid mine drainage (AMD), or any sulfate containing water resource, to remove strontium, barium, and/or radium from contaminated water sources, such as but not limited to hydraulic fracturing waste water, flowback, and/or produced water, without requiring any external regenerant. The removal process may be adopted with any waste water or impaired water source containing sulfate anions.

公开(公告)号：US20180311736A1

公开(公告)日：2018-11-01

申请号：US15965266

申请日：2018-04-27

申请人： TE Connectivity Corporation ,  Lehigh University

发明人： Gregory Thomas Pawlikowski ,  Martin William Bayes ,  Anthony P. Ventura ,  Wojciech Z. Misiolek

IPC分类号： B22F3/105 ,  B22F1/00

摘要： In some embodiments, a method of producing a metallic article includes providing a metallic powder, selecting a predetermined concentration for a reactive component, providing a controlled atmosphere including the reactive component at the predetermined concentration, and additively manufacturing the metallic article from the metallic powder under the controlled atmosphere. The metallic powder includes a metallic element or metallic alloy. The reactive component reacts with the metallic powder in a weld pool formed during the additive manufacturing to form a dispersion of nano-particles in the weld pool. The nano-particles are dispersed throughout the metallic article in a substantially uniform manner. In some embodiments, the metallic powder includes the reactive component. Metallic articles formed by the disclosed methods are also disclosed.