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公开(公告)号：US11754648B2
公开(公告)日：2023-09-12
申请号：US17156796
申请日：2021-01-25
IPC分类号： A61B5/00 , G01R33/12 , A61B5/0515 , A61K49/18
CPC分类号： G01R33/1269 , A61B5/0515 , A61K49/1806 , A61K49/1818 , G01R33/1276
摘要： A significant enhancement of detection capabilities of the room temperature MPQ is seen using optical lithography-defined, ferromagnetic iron-nickel alloy microdisks. Irreversible transitions between strongly non-collinear (vortex) and a collinear single domain states, driven by an ac magnetic field, translate into a nonlinear magnetic response that enables ultrasensitive detection of material at relatively small magnetic fields.
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公开(公告)号：US11738336B2
公开(公告)日：2023-08-29
申请号：US16791759
申请日：2020-02-14
发明人： Patrick Braganca , Daniel Bedau
CPC分类号： B01L3/502 , G01N24/00 , G01N27/72 , H01F10/329 , H01F10/3259 , H01F10/3286 , H03B15/006 , B01L2300/0663 , B01L2400/043 , G01R33/1284
摘要： Disclosed herein is a detection device comprising sensors with spin torque oscillators (STOs), at least one fluidic channel configured to receive molecules to be detected, and detection circuitry coupled to the sensors. At least some of the molecules to be detected are labeled by magnetic nanoparticles (MNPs). The presence of one or more MNPs in the vicinity of a STO subjected to a bias current changes the oscillation frequency of the STO. The sensors are encapsulated by a material, such as an insulator, separating the sensors from the at least one fluidic channel. A surface of the material provides binding sites for the molecules to be detected. The detection circuitry is configured to detect changes in the oscillation frequencies of the sensors in response to presence or absence of one or more MNPs coupled to one or more binding sites associated with the sensors.
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公开(公告)号：US20230266412A1
公开(公告)日：2023-08-24
申请号：US17652246
申请日：2022-02-23
CPC分类号： G01R33/1276 , G01N27/74
摘要： A tracer composition includes a carrier fluid and a tracer particle that includes at least one magnetic material and an acoustic signal generating material. A method includes introducing a tracer composition into a reservoir at a first location. The method further includes collecting fluid from the reservoir at a second location, where the first location is different from the second location. The method also includes applying a magnet field to the fluid collected from the reservoir such that the magnetic material produces vibrational energy. Due to the vibrational energy generated in the magnetic material, thermal energy is transferred to the acoustic signal generating material thereby heating the acoustic signal generating material to a boiling point such that the acoustic signal is generated. The method further includes detecting the acoustic signal and correlating the acoustic signal to a tracer particle concentration.
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公开(公告)号：US11733324B2
公开(公告)日：2023-08-22
申请号：US17483809
申请日：2021-09-24
发明人： Kazuki Yamauchi , Chungwei Lin
CPC分类号： G01R33/1276 , G01R33/10
摘要： A magnetic particle imaging system includes a field free region generator and an excited magnetic field generator. The field free region generator generates a field free line with a direction of linear extension of a field free region as a direction of extension. The excited magnetic field generator generates an excited magnetic field in the field free line generated by the field free region generator. The excited magnetic field generator includes a first excited magnetic field generation unit and a second excited magnetic field generation unit. The first excited magnetic field generation unit and the second excited magnetic field generation unit are spaced from each other in the direction of extension of the field free line.
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公开(公告)号：US11710590B2
公开(公告)日：2023-07-25
申请号：US16609375
申请日：2018-05-10
CPC分类号： H01F6/06 , C08G61/08 , H01F6/04 , C07F15/0046 , C08G2261/3322 , C08G2261/3324 , G01R33/1238 , H01F6/006
摘要： A superconducting coil device (10) includes: a coil case (20) housing a superconducting coil (30); a superconducting coil (30) housed in the coil case (20); and a resin part (50) formed of a polymer (51) filled in a gap between an inner wall of the coil case (20) and the superconducting coil (30). The resin part (50) is formed of a polymer (51) obtained by polymerizing a polymerizable composition containing a first monomer having a norbornene ring structure.
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公开(公告)号：US11709212B2
公开(公告)日：2023-07-25
申请号：US17581684
申请日：2022-01-21
CPC分类号： G01R33/1276 , G01R33/10
摘要： A pulsed magnetic particle imaging system includes a magnetic field generating system that includes at least one magnet, the magnetic field generating system providing a spatially structured magnetic field within an observation region of the magnetic particle imaging system such that the spatially structured magnetic field will have a field-free region (FFR) for an object under observation having a magnetic nanoparticle tracer distribution therein. The pulsed magnetic particle imaging system also includes a pulsed excitation system arranged proximate the observation region, the pulsed excitation system includes an electromagnet and a pulse sequence generator electrically connected to the electromagnet to provide an excitation waveform to the electromagnet, wherein the electromagnet when provided with the excitation waveform generates an excitation magnetic field within the observation region to induce an excitation signal therefrom by at least one of shifting a location or condition of the FFR. The pulsed magnetic particle imaging system further includes a detection system arranged proximate the observation region, the detection system being configured to detect the excitation signal to provide a detection signal. The excitation waveform includes a transient portion and a substantially constant portion.
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公开(公告)号：US20230221387A1
公开(公告)日：2023-07-13
申请号：US18009808
申请日：2021-02-23
发明人： Jinbo CHI
CPC分类号： G01R33/1207 , G06F11/2221 , G06F11/2273
摘要： A hard disk status testing apparatus, including: a voltage reading module, a controller, an analogue switch, and multiple hard disk slot units. Each hard disk slot unit includes: a hard disk status testing module and a hard disk status indication module. The hard disk status testing modules and the hard disk status indication modules among different hard disk slot units are time-multiplexed, achieving independent control of the hard disk status testing modules of different hard disk slot units and independent control of the hard disk status indication modules of different hard disk slot units. A hard disk status testing method that effectively solves the problem of an increase in the number of pins needed for hard disk status testing and status indication, thus effectively decreasing hardware costs and increasing the utilization rate of pin resources.
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公开(公告)号：US11662401B2
公开(公告)日：2023-05-30
申请号：US17156741
申请日：2021-01-25
申请人： TDK Corporation
发明人： Keisuke Takasugi
IPC分类号： G01R33/09 , G01N33/543 , G01R33/12
CPC分类号： G01R33/091 , G01N33/54326 , G01R33/1269
摘要： A magnetic sensor includes a substrate having a first surface and a second surface, which is opposite the first surface, and a detection unit provided on the first surface. The detection unit includes a magnetoresistive effect element, the resistance value of which changes in accordance with an input magnetic field, provided on the first surface, and a protective layer that covers at least the magnetoresistive effect element. The magnetoresistive effect element is configured in a linear shape extending in a first direction on the first surface. The detection unit has a first width, which is a length in a second direction, orthogonal to the first direction, and a second length, which is greater than the first width. The first width is the length of the detection unit on the first surface, and the second width is the length of the top surface of the detection unit.
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公开(公告)号：US20230102733A1
公开(公告)日：2023-03-30
申请号：US18061231
申请日：2022-12-02
发明人： Todd Michael KLEIN , Michael Monroe Reinhart SANDSTEDT , John Frank PROVOS , Chad Brian RHEAULT
IPC分类号： G01N27/12 , G01N33/18 , G01N33/487 , G01N33/49 , G01N33/543 , B01L3/00 , G01N27/74 , G01N33/493 , G01R33/09 , G01R33/12
摘要： A system for detecting analytes in a test sample, and a method for processing the same, is provided. The system includes a cartridge reader unit that has a control unit and a pneumatic system, and a cartridge assembly that prepares the samples with mixing material(s) through communication channels. The assembly has a memory chip with parameters for preparing the sample and at least one sensor. The assembly, pneumatic system, and control unit operate together to prepare the sample and provide the prepared sample to the sensor for detecting analytes, and also process measurements from the sensor to generate test results.
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公开(公告)号：US11579216B1
公开(公告)日：2023-02-14
申请号：US17877945
申请日：2022-07-31
摘要： A multi-color quantitative magnetic nanoparticle imaging method and system based on trapezoidal wave excitation solves the problem that the existing technology cannot implement multi-color quantitative magnetic particle imaging. The method includes: constructing, based on hysteresis effect and hysteresis inertial growth differences of n superparamagnetic iron oxide nanoparticles (SPIOs) under trapezoidal wave excitation, an equation set of quality of n SPIOs in a to-be-tested sample formed by any composition of n SPIO standard products; solving the equation set to obtain the quality distribution of the to-be-tested sample at position r; and performing rearrangement, color assignment, and image merging on the quality distribution to implement multi-color quantitative imaging of various particles in magnetic particle imaging (MPI). The method broadens the functions of MPI to realize multi-color quantitative imaging, such that MPI has greater potential for application in the medical field.
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