公开(公告)号：US08305865B2

公开(公告)日：2012-11-06

申请号：US12893268

申请日：2010-09-29

Applicant: Satoshi Inoue ,  Yuta Yoshida ,  Naoto Hashimoto ,  Suguru Takishima

Inventor： Satoshi Inoue ,  Yuta Yoshida ,  Naoto Hashimoto ,  Suguru Takishima

IPC: G11B7/135

CPC classification number: G11B7/1374

Abstract: An objective lens for an optical information recording/reproducing optical system for an optical disc letting a laser beam impinge on a recording layer of the optical disc, and wherein a center wavelength λ (unit: nm) of the laser beam is in a range defined by a condition: 390≦λ≦420, a base material of the objective lens is made of resin, the resin has a glass transition temperature Tg and light transmissivity T (unit: %) per a path length of 3 mm at a wavelength of 406 nm defined by conditions: Tg≧115° C., 85≦T≦90, same antireflection films or different types of antireflection films are respectively formed on optical surfaces of the objective lens, and each of the antireflection films formed on the objective lens has a thickness of 100 nm or more in a vicinity of an optical axis of the objective lens.

Abstract translation: 一种用于光盘的光学信息记录/再现光学系统的物镜，其使激光束照射在光盘的记录层上，并且其中激光束的中心波长λ（单位：nm）在限定的范围内 通过条件：390＆nlE;λ＆nlE; 420，物镜的基材由树脂制成，树脂的玻璃化转变温度Tg和光透射率T（单位：％），每个路径长度为3mm，波长为 由条件限定的406nm：Tg≥115℃，85＆lt; NE; T＆lt; NE; 90，在物镜的光学表面上分别形成相同的防反射膜或不同类型的抗反射膜，并且形成在物镜上的每个防反射膜 在物镜的光轴附近具有100nm以上的厚度。

公开(公告)号：US08279738B2

公开(公告)日：2012-10-02

申请号：US12330861

申请日：2008-12-09

Applicant: Satoshi Inoue ,  Daisuke Koreeda ,  Shuichi Takeuchi

Inventor： Satoshi Inoue ,  Daisuke Koreeda ,  Shuichi Takeuchi

IPC: G11B7/00 ,  G11B7/135 ,  G02B23/24

CPC classification number: G11B7/13922 ,  G11B7/0908 ,  G11B7/1374 ,  G11B2007/0006

Abstract: There is provided an objective lens for information recording/reproducing for three types of optical discs, which includes a first area contributing to converging a third light beam onto a record surface of a third optical disc. The first area includes a phase shift structure having refractive surface zones concentrically formed about a predetermined axis. The phase shift structure includes first and second step groups. The first step group is configured such that an optical path length difference ΔOPD1 (nm) given by each step of the first step group to a first light beam satisfies a condition: 2N1+1.10

Abstract translation: 提供了一种用于三种类型的光盘的信息记录/再现的物镜，其包括有助于将第三光束会聚到第三光盘的记录表面上的第一区域。 第一区域包括具有围绕预定轴线同心地形成的折射表面区域的相移结构。 相移结构包括第一和第二步骤组。 第一步骤组被配置为使得第一步骤组的每个步骤给出的第一光束的光程长度差Dgr; OPD1（nm）满足条件：2N1 + 1.10 <|＆Dgr; OPD1 /λ1| <2N1 +1.40，其中N1是整数或零，并且第二步骤组被配置为使得由第二步骤组的每个步骤给予的第一光束的光程长度差Dgr; OPD2（nm）满足条件：2N2 -0.10 <|＆Dgr; OPD2 /λ1| <2N2 + 0.10，其中N2是整数。

公开(公告)号：US20120060231A1

公开(公告)日：2012-03-08

申请号：US13320674

申请日：2010-05-17

Applicant: Satoshi Inoue ,  Tomohiko Urano ,  Yasuyoshi Ouchi ,  Masataka Shiraki

Inventor： Satoshi Inoue ,  Tomohiko Urano ,  Yasuyoshi Ouchi ,  Masataka Shiraki

IPC: A01K67/027 ,  C12Q1/68 ,  C12N5/077 ,  A61P3/04 ,  C07K7/08 ,  A61K49/00 ,  G01N33/53 ,  C40B30/04 ,  C07K16/18

CPC classification number: A61K31/198 ,  A01K2217/052 ,  A01K2217/075 ,  A01K2267/0362 ,  A61K31/496 ,  A61K31/519 ,  A61K31/5377 ,  A61K38/04 ,  A61K45/06 ,  C07K14/705 ,  C07K16/18 ,  C07K2317/34 ,  C12N15/8509 ,  C12Q1/6883 ,  C12Q2600/136 ,  C12Q2600/156 ,  C12Q2600/172 ,  G01N33/6893 ,  G01N2500/00 ,  G01N2800/044 ,  A61K2300/00

Abstract: It is an object of the present invention to provide a method of evaluating whether or not a subject has a predisposition to obesity or an obesity-related condition or disease, a kit for conducting the method, an anti-obesity drug having an effect of preventing or treating obesity or an obesity-related condition or disease, a method of screening the anti-obesity drug, a non-human animal having a deficiency in the gene associated with obesity, and an adipose tissue or adipocyte of the animal.The method of evaluating a predisposition to obesity of the present invention is a method of evaluating whether or not a subject has a predisposition to obesity or an obesity-related condition or disease. The method includes the step of detecting a copy number variation (CNV) in intron 1 of SLC25A24 gene or a gene polymorphism having a linkage disequilibrium relationship with the CNV in a sample containing a human gene of the subject. If the CNV in intron 1 of the SLC25A24 gene is 0, the subject may be evaluated to have a predisposition to obesity or an obesity-related condition or disease.

Abstract translation: 本发明的目的是提供一种评估受试者是否具有肥胖或肥胖相关病症或疾病倾向的方法，用于进行该方法的试剂盒，具有预防作用的抗肥胖药物 或治疗肥胖或肥胖相关病症或疾病，筛选抗肥胖药物的方法，与肥胖相关基因缺陷的非人动物以及动物的脂肪组织或脂肪细胞。 评估本发明的肥胖倾向的方法是评估受试者是否具有肥胖或肥胖相关病症或疾病倾向的方法。 该方法包括检测SLC25A24基因的内含子1中的拷贝数变异（CNV）或在含有受试者的人类基因的样品中与CNV具有连锁不平衡关系的基因多态性的步骤。 如果SLC25A24基因的内含子1中的CNV为0，则可以评估受试者对肥胖或肥胖相关病症或疾病的易感性。

公开(公告)号：US08124754B2

公开(公告)日：2012-02-28

申请号：US12642979

申请日：2009-12-21

Applicant: Satoshi Inoue ,  Kazuhiro Ikeda

Inventor： Satoshi Inoue ,  Kazuhiro Ikeda

IPC: C07H21/02 ,  C07H21/04 ,  C12N15/11

CPC classification number: A61K48/005 ,  A61K31/7088 ,  A61K31/713 ,  C12N15/113 ,  C12N2310/14

Abstract: A double-stranded nucleic acid molecule for suppressing the expression of at least one of COX7RP and Efp genes which includes (a) a sense strand which includes a nucleotide sequence corresponding to a target sequence indicated by any one of SEQ ID Nos.: 1 to 38 and (b) an antisense strand which includes a nucleotide sequence complementary to that of the sense strand specified in (a); a cancer cell proliferation inhibitor with the double-stranded nucleic acid molecule and against at least one of uterine, breast and bladder cancer cells; and a pharmaceutical agent with the cancer cell proliferation inhibitor and against at least one of uterine, breast and bladder cancers.

Abstract translation: 用于抑制COX7RP和Efp基因中的至少一种表达的双链核酸分子，其包括（a）有义链，其包含对应于由SEQ ID NO：1至 38和（b）反义链，其包含与（a）中规定的有义链的核苷酸序列互补的核苷酸序列; 具有双链核酸分子和针对子宫，乳腺和膀胱癌细胞中的至少一个的癌细胞增殖抑制剂; 以及具有癌细胞增殖抑制剂和针对子宫，乳腺和膀胱癌中的至少一种的药剂。

公开(公告)号：US20120043536A1

公开(公告)日：2012-02-23

申请号：US13319072

申请日：2010-03-24

Applicant: Satoshi Inoue

Inventor： Satoshi Inoue

IPC: H01L51/52 ,  H01L51/56

CPC classification number: H01L51/56 ,  B41M5/265 ,  B41M5/38221 ,  H01L27/3211 ,  H01L27/3281 ,  H01L51/001 ,  H01L51/0013 ,  H05B33/10

Abstract: A donor film 40 including an organic donor layer 42 and a transfer target substrate 12 including a lower electrode 7 are prepared. The organic donor layer 42 is thermally transferred to the top of the lower electrode 7 of the transfer target substrate 12 to form an organic layer 17 by placing the donor film 40 between the transfer target substrate 12 and a thermal head 38 and bringing the transfer target substrate 12 and the thermal head 38 into close contact with each other by magnetic attraction of a magnetic body 4, and then an upper electrode is formed on the organic layer 17, to obtain an organic EL element. This provides an organic EL element with excellent quality free from unevenness in the transfer of the organic donor layer from the donor film even when the transfer target substrate is large in size.

Abstract translation: 制备包括有机施主层42的供体膜40和包括下电极7的转印靶基板12。 有机供体层42通过将施主膜40放置在转印靶基板12和热敏头38之间而将转印目标基板12的下部电极7的顶部热传递到有机层17，并将转印目标 基板12和热敏头38通过磁性体4的磁吸引而彼此紧密接触，然后在有机层17上形成上部电极，以获得有机EL元件。 这提供了有机EL元件，即使当转印目标基板尺寸较大时，也能够有效地提供有机供体层从施主膜的转印不均匀的质量。

公开(公告)号：US20120029023A1

公开(公告)日：2012-02-02

申请号：US13242702

申请日：2011-09-23

Applicant: Keigo TANAKA ,  Satoshi Inoue ,  Norio Murai ,  Masayuki Matsukura ,  Kazutaka Nakamoto ,  Shuji Shirotori ,  Shinya Abe

Inventor： Keigo TANAKA ,  Satoshi Inoue ,  Norio Murai ,  Masayuki Matsukura ,  Kazutaka Nakamoto ,  Shuji Shirotori ,  Shinya Abe

IPC: A61K31/4439 ,  A61P31/10 ,  A61K31/444 ,  C07D401/14 ,  C07D401/04

CPC classification number: A01N43/56 ,  A01N43/80 ,  C07D401/04 ,  C07D401/14 ,  C07D413/04 ,  C07D413/14 ,  C07D417/14

Abstract: An object of the present invention is to provide an antifungal agent which has excellent antifungal effects and is superior in terms of its physical properties, safety and metabolic stability. According to the present invention, there is disclosed a compound represented by the following formula (I), or a salt thereof: wherein R1, R2, X, Y, ring A, Z, R3 and R4 are as defined in the specification.

Abstract translation: 本发明的目的是提供一种具有优异的抗真菌作用并且在其物理性质，安全性和代谢稳定性方面优异的抗真菌剂。 根据本发明，公开了由下式（I）表示的化合物或其盐：其中R1，R2，X，Y，环A，Z，R3和R4如说明书中所定义。

公开(公告)号：US20110277494A1

公开(公告)日：2011-11-17

申请号：US13145741

申请日：2010-01-20

Applicant: Tomonori Kikuno ,  Satoshi Inoue ,  Akihiro Fujiwara ,  Hyunyoung Kim ,  Yoshikazu Shiraishi ,  Kaori Yoshida ,  Takayuki Hyoudou

Inventor： Tomonori Kikuno ,  Satoshi Inoue ,  Akihiro Fujiwara ,  Hyunyoung Kim ,  Yoshikazu Shiraishi ,  Kaori Yoshida ,  Takayuki Hyoudou

IPC: F25B30/00 ,  F28F1/00

CPC classification number: F24D17/02 ,  F28D7/0033 ,  F28D7/04 ,  F28F1/022 ,  F28F3/02 ,  F28F3/044 ,  F28F13/12 ,  F28F2225/04

Abstract: A heat exchanger 21 is provided with a metal tube 47 that has a support member 55 inhibiting deformation in the thickness direction in a fluid flow channel 53, and a multiple-hole metal tube 45 that is stacked on one side of the metal tube 47 in the thickness direction and has an opposing surface disposed opposite an outer surface 61 on the one side of the metal tube 47 and joined by at least part thereof to the outer surface 61 on the one side.

Abstract translation: 热交换器21设置有金属管47，金属管47具有阻止流体流路53中的厚度方向变形的支撑构件55，以及堆叠在金属管47的一侧上的多孔金属管45 厚度方向并且具有与金属管47的一侧上的外表面61相对设置并且至少部分地连接到一侧的外表面61的相对表面。

公开(公告)号：US07910271B2

公开(公告)日：2011-03-22

申请号：US11577304

申请日：2005-10-07

Applicant: Satoshi Inoue

Inventor： Satoshi Inoue

IPC: H05B33/00 ,  G02B5/20 ,  H01L33/00

CPC classification number: H01L51/0005 ,  H01L27/3246 ,  H01L51/0018 ,  H05B33/26 ,  Y10T428/24802

Abstract: An organic EL device includes a substrate body, a plurality of organic functional layers arranged on the substrate body in a given pattern and a partition for partitioning the plural organic functional layers. The partition includes at least a first partition part with a substantially trapezoidal cross-section provided on the substrate body and a second partition part with a substantially trapezoidal cross-section provided on the first partition part. The partition is formed so that a lower base of the cross-section of the second partition part can be shorter than an upper base of the cross-section of the first partition part.

Abstract translation: 有机EL器件包括基板主体，以给定图案布置在基板主体上的多个有机功能层和用于划分多个有机功能层的隔板。 所述隔板至少包括设置在所述基板主体上的具有大致梯形截面的第一分隔部和设置在所述第一分隔部上的具有大致梯形截面的第二分隔部。 隔壁形成为使得第二分隔部分的横截面的下基部可以比第一分隔部分的横截面的上基部短。

公开(公告)号：US07869085B2

公开(公告)日：2011-01-11

申请号：US10921267

申请日：2004-08-19

Applicant: Kohtaro Nemoto ,  Tetsujiro Kondo ,  Nobuyuki Asakura ,  Satoshi Inoue ,  Wataru Niitsuma ,  Tatsuya Ishii ,  Takahide Ayata ,  Masanori Yamanaka ,  Yasushi Tatehira

Inventor： Kohtaro Nemoto ,  Tetsujiro Kondo ,  Nobuyuki Asakura ,  Satoshi Inoue ,  Wataru Niitsuma ,  Tatsuya Ishii ,  Takahide Ayata ,  Masanori Yamanaka ,  Yasushi Tatehira

IPC: G06F15/00 ,  G06K15/00 ,  H04N1/405 ,  G03F3/08

CPC classification number: G09G5/005 ,  G09G3/20 ,  G09G5/006 ,  G09G2340/0407

Abstract: A luminance signal Ya and a color-difference signal Ua/Va constituting an input image signal is transferred to a frame memory (first memory) in the unit of line synchronously with its horizontal synchronous signal and written therein. A memory TG211 reads out a read-out request RRQ. The cycle of this request RRQ is a time computed based on a single vertical effective period of an output image signal Sc and the number of lines objective for rate conversion of an input image signal Sa. The luminance signal Ya and color-difference signal Ua/Va are transferred in the unit of line from the frame memory to rate conversion units (second memory) through buffers. There occurs no deflection in this transfer cycle and in each transfer cycle, the stable data transmission band can be secured.

Abstract translation: 构成输入图像信号的亮度信号Ya和色差信号Ua / Va与其水平同步信号同步地被传送到帧存储器（第一存储器）并写入其中。 存储器TG211读出读出请求RRQ。 该请求RRQ的周期是基于输出图像信号Sc的单个垂直有效周期和输入图像信号Sa的速率转换的行数目的计算的时间。 亮度信号Ya和色差信号Ua / Va以行为单位从帧存储器传送到速率转换单元（第二存储器）通过缓冲器。 在该传送周期中，在每个传送周期中不发生偏转，可以确保稳定的数据传输带。

公开(公告)号：US07810352B2

公开(公告)日：2010-10-12

申请号：US11544355

申请日：2006-10-09

Applicant: Hiroshi Mieda ,  Seiji Inoue ,  Satoshi Inoue

Inventor： Hiroshi Mieda ,  Seiji Inoue ,  Satoshi Inoue

IPC: F25B15/00

CPC classification number: F25B35/04 ,  F28F13/003 ,  F28F13/185 ,  Y02A30/277 ,  Y02A30/278 ,  Y02B30/62 ,  Y02B30/64 ,  Y10T117/1068

Abstract: A heat exchanger having an adsorbing core is advantageously applied to a refrigerating system mounted on an automotive vehicle. The adsorbing core absorbs heat from coolant and gives heat to the coolant thereby to perform heat-exchanging operation. The adsorbing core is composed of a heat exchanging member such as tubes or fins of the heat exchanger and a attracting layer connected to the surface of the heat exchanging member. A seed crystal retaining layer is firmly connected to the surface of the heat exchanging member, and the attractant crystals forming the attractant layer are grown on the seed crystals by a hydrothermal crystal growth method. Since the attracting layer is uniformly formed and firmly connected to the surface of the heat exchanging member, heat is quickly transferred between the attractant layer and the heat exchanging member.

Abstract translation: 具有吸附芯的热交换器有利地应用于安装在机动车上的制冷系统。 吸附芯从冷却剂吸收热量并向冷却剂供热，从而进行热交换操作。 吸附芯由热交换器的管或翅片等热交换构件和与热交换构件的表面连接的吸附层构成。 晶种保持层牢固地连接到热交换构件的表面，并且通过水热晶体生长法在晶种上生长形成引诱层的引诱剂晶体。 由于吸引层均匀地形成并牢固地连接到热交换构件的表面，所以在引诱层和热交换构件之间快速地传递热量。