公开(公告)号：US10131866B2

公开(公告)日：2018-11-20

申请号：US14769128

申请日：2013-03-20

Applicant: Direvo Industrial Biotechnology GmbH ,  BASF Enzymes, LLC

Inventor： Christian Elend ,  Marco Krämer

IPC: C12H1/00 ,  A23K10/38

Abstract: The present technology relates to novel mycotoxin binder and the use in animal feed. The present disclosure relates also to the use of enzymes for improving the mycotoxin binding ability of by-products derived from a fermentative production process and to compositions comprising enzymes capable of degrading components in the fermented mash in the fermentation process.

公开(公告)号：US10100299B2

公开(公告)日：2018-10-16

申请号：US13674199

申请日：2012-11-12

Applicant: BASF Enzymes LLC ,  Syngenta Participation AG

Inventor： Malgorzata Slupska ,  Geoff Hazlewood ,  Cathy Chang ,  Peter Luginbuhl ,  Ellen Burke ,  Michelle Cayouette ,  Uvini Gunawardena ,  Majid Ghassemian ,  Aron Silverstone ,  Yan Zhang

IPC: C12P7/10 ,  C12P7/06 ,  C12N9/34 ,  C12N9/26 ,  C12N9/24 ,  C12N9/14 ,  C12N9/10 ,  C12P21/06 ,  C12P19/34 ,  C12N15/00 ,  C07H21/04 ,  C07K1/00 ,  C12N9/96

Abstract: In one aspect, the invention is directed to polypeptides having an amylase and/or glucoamylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of polysaccharide, oligosaccharide or starch into sugars. In one aspect, the invention provides delayed release compositions comprising an desired ingredient coated by a latex polymer coating. In alternative embodiments, enzymes are used to make biofuels, e.g., ethanol, butanol, propanol, or a gasoline-ethanol mix, including a bioethanol, biopropanol, biobutanol, or a biodiesel, or for any form of fuel or biomass processing.

公开(公告)号：US10047350B2

公开(公告)日：2018-08-14

申请号：US15135732

申请日：2016-04-22

Applicant: BASF ENZYMES LLC

Inventor： Walter Callen ,  Toby Richardson ,  Gerhard Frey ,  Jay M. Short ,  Eric J. Mathur ,  Kevin A. Gray ,  Janne S. Kerovuo ,  Malgorzata Slupska

IPC: C12N9/28 ,  C12P19/14 ,  C12N9/26 ,  A21D8/04 ,  C12P19/04

CPC classification number: C12N9/2417 ,  A21D8/042 ,  C12N9/2414 ,  C12P19/04 ,  C12P19/14 ,  C12Y302/01001 ,  Y02E50/16 ,  Y02E50/17

Abstract: The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at acidic, neutral and alkaline pH and increased temperature.

公开(公告)号：US09879238B2

公开(公告)日：2018-01-30

申请号：US14771143

申请日：2014-03-10

Applicant: BASF Enzymes LLC

Inventor： Xuqiu Tan ,  Arne I. Solbak, Jr.

IPC: C12N9/24 ,  C12N9/16

CPC classification number: C12N9/16 ,  C12Y301/03008

Abstract: Polypeptides having phytase activity and polynucleotide sequences encoding the phytases are provided. The gene expresses the phytase at a level of at least 7 g/L to 40 g/L. The phytase have higher specific activity, retain activity at low pH, and retain activity at high temperature. The phytase can be used in a variety of compositions including food, feed, pharmaceuticals, and cleaning.

公开(公告)号：US20170218298A1

公开(公告)日：2017-08-03

申请号：US15501533

申请日：2015-06-23

Applicant: DIREVO Industrial Biotechnology GmbH ,  BASF Enzymes, LLC

Inventor： Marco Kraemer ,  Vitaly Svetlitchnyi

IPC: C11B1/02 ,  C12P19/02 ,  C12P7/14 ,  C12P19/14

CPC classification number: C11B1/025 ,  A23K10/38 ,  C11B13/00 ,  C12P7/065 ,  C12P7/10 ,  C12P7/14 ,  C12P19/02 ,  C12P19/14 ,  C12P2203/00 ,  Y02E50/16 ,  Y02E50/17 ,  Y02P60/873

Abstract: The present technology relates to processes of fermenting a starch-containing material into a fermentation product comprising a fermentation step in the presence of a xylanase in combination with a pectinase on oil partitioning during post-fermentation processing. In particular, the enzyme(s) were added during simultaneous saccharification and fermentation. The finished beer was subjected to beer well incubation, distillation, and then decanting to separate thin stillage from the solids.

公开(公告)号：US09719079B2

公开(公告)日：2017-08-01

申请号：US15009414

申请日：2016-01-28

Applicant: BASF Enzymes LLC

Inventor： David P. Weiner ,  Lishan Zhao ,  Peter Luginbuhl ,  Ellen Burke ,  Toby H. Richardson ,  Paula M. Hicks

IPC: C12N9/10 ,  C12Q1/68 ,  C12P21/04 ,  C12P21/06 ,  C12N15/00 ,  C12N1/20 ,  C07H21/04 ,  C12N9/88 ,  C12N15/82 ,  C12P17/10 ,  A61K38/00

CPC classification number: C12N9/88 ,  A01K2217/05 ,  A61K38/00 ,  C07K2317/92 ,  C12N9/1022 ,  C12N15/8243 ,  C12P17/10 ,  C12Y401/03016 ,  C12Y401/03017 ,  Y02E50/16 ,  Y02E50/17

Abstract: This invention relates to polypeptides having aldolase activity, including pyruvate activity such as, without limitation, HMG and/or KHG aldolase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In some embodiments, the invention is directed to polypeptides having aldolase activity, including pyruvate activity such as, without limitation, HMG and/or KHG aldolase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides in accordance with the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts. In some embodiments, the invention provides polypeptides and biosynthetic pathways that are useful in the production of R-2-hydroxy 2-(indol-3ylmethyl)-4-keto glutaric acid (R-MP) and certain stereoisomers of monatin, such as R,R and S,R monatin, and salts thereof, as well as certain stereoisomers of monatin derivatives, such as the R,R and S,R configurations, and salts thereof.

公开(公告)号：US20160264951A1

公开(公告)日：2016-09-15

申请号：US15135732

申请日：2016-04-22

Applicant: BASF ENZYMES LLC

Inventor： WALTER CALLEN ,  TOBY RICHARDSON ,  GERHARD FREY ,  JAY M. SHORT ,  ERIC J. MATHUR ,  KEVIN A. GRAY ,  JANNE S. KEROVUO ,  MALGORZATA SLUPSKA

IPC: C12N9/28 ,  C12P19/04 ,  A21D8/04 ,  C12P19/14

CPC classification number: C12N9/2417 ,  A21D8/042 ,  C12N9/2414 ,  C12P19/04 ,  C12P19/14 ,  C12Y302/01001 ,  Y02E50/16 ,  Y02E50/17

Abstract: The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at acidic, neutral and alkaline pH and increased temperature.

Abstract translation: 本发明涉及α-淀粉酶和编码α-淀粉酶的多核苷酸。 另外还提​​供了设计新的α-淀粉酶的方法及其使用方法。 在酸性，中性和碱性pH和升高的温度下，α-淀粉酶具有增加的活性和稳定性。

公开(公告)号：US20160068832A1

公开(公告)日：2016-03-10

申请号：US14832603

申请日：2015-08-21

Applicant: BASF Enzymes LLC

Inventor： David P. WEINER ,  Alexander VARVAK ,  Toby RICHARDSON ,  Mircea PODAR ,  Ellen BURKE ,  Shaun HEALEY

IPC: C12N9/88 ,  C12P13/24 ,  D06M16/00 ,  C12P13/22

CPC classification number: C12N9/88 ,  C12P7/42 ,  C12P13/222 ,  C12P13/225 ,  C12P13/24 ,  C12Y403/01005 ,  C12Y403/01023 ,  D06M16/003

Abstract: This invention provides polypeptides having lyase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides having ammonia lyase activity, e.g., phenylalanine ammonia lyase, tyrosine ammonia lyase and/or histidine ammonia lyase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts.

Abstract translation: 本发明提供了具有裂解酶活性的多肽，编码这些多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。 一方面，本发明涉及具有氨裂解酶活性的多肽，例如苯丙氨酸氨裂解酶，酪氨酸氨裂解酶和/或组氨酸氨裂解酶活性，包括耐热和耐热活性，以及​​编码这些酶的多核苷酸，以及制备和使用这些多核苷酸 和多肽。 本发明的多肽可用于多种药物，农业和工业环境。

公开(公告)号：US20240301451A1

公开(公告)日：2024-09-12

申请号：US18665634

申请日：2024-05-16

Applicant: BASF Enzymes LLC

Inventor： Brian Hoskins ,  Anthony V. Newton ,  Yun Han ,  Joseph P. Borst

IPC: C12P7/64 ,  C12N9/26 ,  C12P7/06

CPC classification number: C12P7/64 ,  C12N9/2414 ,  C12P7/06 ,  C12Y302/01001

Abstract: A method for increasing the oil yield in an ethanol production process comprising: adding a liquid enzyme formulation having at least one enzyme, a buffering agent, a stabilizer, and a preservative where the pH of the enzyme formulation is about pH 6.0-8.0 to a beer, a distillation, a whole stillage, a centrifugation, a thin stillage, an evaporator, a syrup, or an oil recovery unit.

公开(公告)号：US20210207176A1

公开(公告)日：2021-07-08

申请号：US17050054

申请日：2019-05-23

Applicant: BASF SE ,  BASF Enzymes LLC

Inventor： Yukiko SATO ,  Frank REINHOLD ,  Justin Andrew BORDLEY ,  Joseph P BORST ,  Matthew Gerard LYON ,  Christopher Paul MYERS ,  Katrina Marie KNAUER

IPC: C12P7/06 ,  C12P19/14

Abstract: Disclosed herein include methods of reducing the viscosity of a starch slurry during starch processing by the addition of one or more surfactants and one or more amylases. In some embodiments, the unexpected reduction in slurry viscosity results in a surprising increase in corn oil recovery, reduction in residual starch, and increased fermentation rate.