公开(公告)号：US5937826A

公开(公告)日：1999-08-17

申请号：US33338

申请日：1998-03-02

Applicant: David Olson ,  Keith L. Musser ,  Stephen West ,  Shyamala Raghunathan ,  Jonathan A. Stavnheim

Inventor： David Olson ,  Keith L. Musser ,  Stephen West ,  Shyamala Raghunathan ,  Jonathan A. Stavnheim

IPC: F02M41/00 ,  F02D41/22 ,  F02D41/40 ,  F02M41/02 ,  F02M59/36 ,  F02M63/00 ,  F02M7/00

CPC classification number: F02M59/366 ,  F02D41/221 ,  F02D41/3845 ,  F02D41/406 ,  F02M41/02 ,  F02D2041/227 ,  F02M2200/40 ,  Y02T10/44

Abstract: A fuel system includes an electronically controllable high pressure fuel pump operable to supply high pressure fuel from a lower pressure fuel source to a high pressure fuel collection chamber having a pressure sensor associated therewith. The fuel collection chamber feeds an electronically controllable valve operable to dispense the high pressure fuel to a fuel distribution unit supplying fuel to a number of fuel injectors. A control computer is provided for controlling the high pressure fuel pump and valve in response to requested fueling, engine speed and fuel pressure provided by the pressure sensor. The control computer is normally operable to drive the fuel pump as a function of fuel pressure and a reference pressure, which is based on requested fueling, and to control the valve as a function of commanded fueling, which is a function of engine speed and a reference speed based on requested fueling, and fuel pressure. In a first limp home mode, the control computer is operable to drive the fuel pump as a function of fuel pressure and commanded fueling if abnormal operation of the high pressure fuel pump is detected. In this mode, the valve is controlled only as a function of fuel pressure. In a second limp home mode, the control computer is operable to drive the fuel pump with a predicted fuel pump command based on the fuel command and engine speed, if abnormal operation of the pressure sensor is detected. In this mode, the valve is controlled as a function of the fuel command and the reference pressure or a default pressure.

Abstract translation: 燃料系统包括电子可控的高压燃料泵，其可操作以将来自低压燃料源的高压燃料供应到具有与其相关联的压力传感器的高压燃料收集室。 燃料收集室供应电子可控阀，可操作以将高压燃料分配到向多个燃料喷射器供应燃料的燃料分配单元。 提供控制计算机，用于响应于由压力传感器提供的所需的加油，发动机转速和燃料压力来控制高压燃料泵和阀。 控制计算机通常可操作地驱动作为燃料压力和参考压力的函数的燃料泵，其基于所要求的加燃料，并且根据作为发动机转速的函数来控制阀作为指令的加油功能， 基于所需加油的参考速度和燃料压力。 在第一跛行家庭模式中，如果检测到高压燃料泵的异常操作，则控制计算机可操作地作为燃料压力的函数驱动燃料泵和指令的燃料。 在这种模式下，阀门仅作为燃油压力的控制。 在第二跛行模式中，如果检测到压力传感器的异常操作，则控制计算机可操作以基于燃料命令和发动机速度的预测燃料泵命令驱动燃料泵。 在此模式下，根据燃油指令和参考压力或默认压力来控制阀门。

公开(公告)号：US3241268A

公开(公告)日：1966-03-22

申请号：US34672764

申请日：1964-02-24

Applicant: DAVID OLSON

Inventor： DAVID OLSON

IPC: B24D9/08

CPC classification number: B24D9/08

公开(公告)号：US09880152B2

公开(公告)日：2018-01-30

申请号：US13980544

申请日：2012-01-23

Applicant: Nardhy Gomez-Lopez ,  David Olson

Inventor： Nardhy Gomez-Lopez ,  David Olson

IPC: G01N33/50 ,  G01N33/68 ,  C12Q1/68

CPC classification number: G01N33/5047 ,  C12Q1/6883 ,  C12Q2600/158 ,  G01N33/6893 ,  G01N2800/368

Abstract: Described herein are compositions, methods and/or kits for determining the likelihood of a pregnant subject delivering at term, or developing a disorder associated with pregnancy. These compositions, methods and/or kits feature the measurement of the chemotactic activity of peripheral leukocytes, the measurement of ccl2 mRNA expression or the measurement of Fp or Otr protein expression.

公开(公告)号：US08507874B2

公开(公告)日：2013-08-13

申请号：US13437329

申请日：2012-04-02

Applicant: Wes From ,  Boyko M. Tchavdarov ,  Mike Marcu ,  Richard Gratton ,  David Olson ,  Jim Fraser ,  Dusko A. Kezele

Inventor： Wes From ,  Boyko M. Tchavdarov ,  Mike Marcu ,  Richard Gratton ,  David Olson ,  Jim Fraser ,  Dusko A. Kezele

IPC: B01J19/08

CPC classification number: C02F1/325 ,  A61L2/10 ,  C02F1/006 ,  C02F1/32 ,  C02F2201/3225 ,  C02F2201/3227 ,  C02F2201/3228 ,  C02F2201/324 ,  C02F2201/328

Abstract: A fluid treatment system having: an inlet; an outlet; and a fluid treatment zone disposed therebetween. The fluid treatment zone has: (i) an elongate first radiation source assembly having a first longitudinal axis, and (ii) an elongate second radiation source assembly having a second longitudinal axis. The first and second longitudinal axes are non-parallel to each other and to a direction of fluid flow through the treatment zone. The present fluid treatment system can treat large volumes of fluid (e.g., wastewater, drinking water or the like); it requires a relatively small “footprint”; it results in a relatively lower coefficient of drag resulting in an improved hydraulic pressure loss/gradient over the length of the treatment system; and it results in relatively lower (or no) forced oscillation of the radiation sources thereby mitigating breakage of the radiation source and/or protective sleeve (if present).

Abstract translation: 一种流体处理系统，具有：入口; 一个出口 以及设置在其间的流体处理区。 流体处理区具有：（i）具有第一纵向轴线的细长的第一辐射源组件，和（ii）具有第二纵向轴线的细长的第二辐射源组件。 第一和第二纵向轴线彼此不平行，并且流过流经处理区域的流体的方向。 本流体处理系统可以处理大量流体（例如，废水，饮用水等）; 它需要相对较小的“足迹”; 它导致相对较低的阻力系数导致在处理系统的长度上改善的液压损失/梯度; 并且其导致辐射源的相对较低（或不）强制振荡，从而减轻辐射源和/或保护套筒（如果存在）的破坏。

公开(公告)号：US20120228219A1

公开(公告)日：2012-09-13

申请号：US13045058

申请日：2011-03-10

Applicant: Phillip GOEBEL ,  David OLSON ,  David M. POLIZZOTTI ,  Abdul Rafi KHWAJA

Inventor： Phillip GOEBEL ,  David OLSON ,  David M. POLIZZOTTI ,  Abdul Rafi KHWAJA

IPC: C02F1/44 ,  B01D71/56 ,  B01D63/10

CPC classification number: B01D63/12 ,  B01D63/106 ,  B01D65/02 ,  B01D2311/04 ,  B01D2311/10 ,  B01D2311/18 ,  B01D2311/2615 ,  B01D2311/2634 ,  B01D2313/143 ,  B01D2313/146 ,  B01D2321/164

Abstract: A spiral wound module is suitable for use with high temperature water that is also very alkaline or has a high pH, for example SAGD produced water. The module uses a polyamide-based membrane with a polysulfone or polyethersulfone backing material. For other components, the module uses primarily one or more of, EPDM; polyamide; polyphenylene oxide; polyphenylene sulfide; polysulfone; polyethersulfone; polysulfonamide; polyvinylidene fluoride; mylar; fiberglass; and, epoxy. Polyester is not used. Polypropylene is not used for the feed spacer. For example, a module may use a PVDF feed spacer, a nylon permeate spacer and a polysulfone center tube. The center tube may be provided with 4 rows of 0.063″ diameter holes and be rolled under high tension.

Abstract translation: 螺旋缠绕模块适用于也是非常碱性或具有高pH的高温水，例如SAGD生产的水。 该模块使用聚酰胺基膜与聚砜或聚醚砜背衬材料。 对于其他组件，模块主要使用一个或多个EPDM; 聚酰胺; 聚苯醚; 聚苯硫醚; 聚砜 聚醚砜 聚磺酰胺 聚偏氟乙烯; 聚酯薄膜 玻璃纤维; 和环氧树脂。 聚酯不使用。 聚丙烯不用于进料间隔物。 例如，模块可以使用PVDF进料间隔物，尼龙渗透物间隔物和聚砜中心管。 中心管可以设置有4排0.063“直径的孔并且在高张力下被轧制。

公开(公告)号：US08229707B2

公开(公告)日：2012-07-24

申请号：US13175926

申请日：2011-07-04

Applicant: David Olson ,  Collin A. Rich ,  Clement James Goebel, III

Inventor： David Olson ,  Collin A. Rich ,  Clement James Goebel, III

IPC: G06F17/40 ,  G06F17/00

CPC classification number: G01N15/1429 ,  G01N35/00712 ,  G01N35/0092

Abstract: A method of extracting and analyzing a data set from a flow cytometer system of the preferred embodiment comprises the steps of (1) running a sample and saving all collected raw data, (2) viewing raw (or “unmodified”) data, (3) modifying the raw data (e.g., scaling and/or culling the raw data), (4) reviewing and saving the modified data, and (5) exporting the saved data. Once the sample has been run and all collected data have been saved, the user can repeat the steps of modifying the raw data, saving the modified data, and exporting the saved data as many times as necessary and/or desirable.

Abstract translation: 从优选实施例的流式细胞仪系统提取和分析数据集的方法包括以下步骤：（1）运行样本并保存所有收集的原始数据，（2）查看原始（或“未修改”）数据，（3 ）修改原始数据（例如，缩放和/或剔除原始数据），（4）查看和保存修改的数据，以及（5）导出保存的数据。 一旦样品运行并且所有收集的数据都被保存，用户可以重复修改原始数据，保存修改的数据，以及根据需要和/或期望导出保存的数据的步骤。

公开(公告)号：US20120027719A1

公开(公告)日：2012-02-02

申请号：US13204774

申请日：2011-08-08

Applicant: Valerie Ashby ,  David Olson

Inventor： Valerie Ashby ,  David Olson

IPC: A61K31/765 ,  A61P9/00 ,  C08G63/91 ,  C07C69/734 ,  C08G63/80 ,  C08G63/676

CPC classification number: C08G63/52 ,  A61L27/18 ,  A61L31/06 ,  C08G63/672 ,  C08L67/04

Abstract: A method of making an aliphatic polyester prepolymer, comprising: reacting, alone or in combination with other reactants, a diol with at least a first diacid (or a diester of said first diacid) to produce an aliphatic polyester prepolymer. The first diacid is preferably a trans-beta-hydromuconic acid (HMA). In some embodiments, the diol contains at least one ether linkage. In some embodiments the diol is further reacted with at a second diacid, or a diester of said second diacid, wherein said second diacid is different from said first diacid. Prepolymers produced from such processes and articles formed therefrom are also described.

Abstract translation: 一种制备脂族聚酯预聚物的方法，其包括：单独或与其它反应物组合使二醇与至少一种第一二酸（或所述第一二酸的二酯）反应以产生脂族聚酯预聚物。 第一种二酸优选是反式-β-水凝胶酸（HMA）。 在一些实施方案中，二醇包含至少一个醚键。 在一些实施方案中，二醇进一步与所述第二二酸的第二二酸或二酯反应，其中所述第二二酸不同于所述第一二酸。 还描述了由这些方法制备的预聚物和由其形成的制品。

公开(公告)号：US07996188B2

公开(公告)日：2011-08-09

申请号：US11466391

申请日：2006-08-22

Applicant: David Olson ,  Collin A. Rich ,  Clement James Goebel, III

Inventor： David Olson ,  Collin A. Rich ,  Clement James Goebel, III

IPC: G01N15/00 ,  G06F17/40

CPC classification number: G01N15/1429 ,  G01N35/00712 ,  G01N35/0092

Abstract: A method of extracting and analyzing a data set from a flow cytometer system of the preferred embodiment comprises the steps of (1) running a sample and saving all collected raw data, (2) viewing raw (or “unmodified”) data, (3) modifying the raw data (e.g., scaling and/or culling the raw data), (4) reviewing and saving the modified data, and (5) exporting the saved data. Once the sample has been run and all collected data have been saved, the user can repeat the steps of modifying the raw data, saving the modified data, and exporting the saved data as many times as necessary and/or desirable.

Abstract translation: 从优选实施例的流式细胞仪系统提取和分析数据集的方法包括以下步骤：（1）运行样本并保存所有收集的原始数据，（2）查看原始（或“未修改”）数据，（3 ）修改原始数据（例如，缩放和/或剔除原始数据），（4）查看和保存修改的数据，以及（5）导出保存的数据。 一旦样品运行并且所有收集的数据都被保存，用户可以重复修改原始数据，保存修改的数据，以及根据需要和/或期望导出保存的数据的步骤。

公开(公告)号：US07808158B1

公开(公告)日：2010-10-05

申请号：US11973993

申请日：2007-09-27

Applicant: Michael Deeds ,  Veronica Valeriano ,  Gerald Laib ,  John Hendershot ,  David Olson

Inventor： Michael Deeds ,  Veronica Valeriano ,  Gerald Laib ,  John Hendershot ,  David Olson

IPC: H02N2/18

CPC classification number: H02N2/185 ,  H01L41/1136

Abstract: An electrical generator includes a fluid-flow driven impeller including at least one impact arm; and at least one cantilevered beam disposed such that the impact arm strikes the cantilevered beam as the impeller rotates. The cantilevered beam at least partially includes a piezoelectric film.

Abstract translation: 发电机包括流体驱动的叶轮，其包括至少一个冲击臂; 以及设置成使得当叶轮旋转时冲击臂撞击悬臂梁的至少一个悬臂梁。 悬臂梁至少部分地包括压电膜。

公开(公告)号：US07807647B2

公开(公告)日：2010-10-05

申请号：US11233312

申请日：2005-09-22

Applicant: Gholamreza Sheikhnejad ,  Neal Goodwin ,  David Olson

Inventor： Gholamreza Sheikhnejad ,  Neal Goodwin ,  David Olson

IPC: A01N43/04 ,  A61K31/70 ,  C12N5/00 ,  C12N5/02 ,  C12N15/00

CPC classification number: A61K31/711

Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.

Abstract translation: 本发明涉及抑制基因表达的方法和组合物。 特别地，本发明提供了用于抑制参与癌症的癌基因的基于寡核苷酸的治疗剂。