Encapsulated inorganic antimicrobial additive for controlled release
    23.
    发明授权
    Encapsulated inorganic antimicrobial additive for controlled release 失效
    封装的无机抗菌添加剂用于控释

    公开(公告)号:US07357949B2

    公开(公告)日:2008-04-15

    申请号:US10032372

    申请日:2001-12-21

    IPC分类号: A61K33/24 A61K47/30 A01N59/16

    摘要: The invention relates to a microcapsule comprising an inorganic antimicrobial agent coated with a hydrophilic polymer. The hydrophilic polymer is able to absorb sufficient water as to enable the action of the encapsulated antimicrobial agent. These microcapsules are useful to impart antimicrobial activity and can be used in polymer compositions, sprays and coatings. A method of preparing the microcapsule by treatment of the antimicrobial agent with a solution of the hydrophilic polymer is provided. Another embodiment of the invention is a method of preparing the microcapsule by coating of the antimicrobial agent with a polymer precursor followed by treatment with a reactive ingredient. Another embodiment of the invention is a method of preparing the microcapsule by melt compounding the antimicrobial agent with the hydrophilic polymer followed by grinding to the desired particle size. Polymer compositions comprising the microcapsules and a matrix polymer are also provided. Another embodiment of the invention is an article prepared from the polymer compositions comprising the microcapsules and a matrix polymer.

    摘要翻译: 本发明涉及包含用亲水性聚合物涂覆的无机抗微生物剂的微胶囊。 亲水性聚合物能够吸收足够的水以使得能够包封的抗微生物剂的作用。 这些微胶囊可用于赋予抗微生物活性,并可用于聚合物组合物,喷雾剂和涂料。 提供了通过用亲水性聚合物溶液处理抗微生物剂来制备微胶囊的方法。 本发明的另一个实施方案是通过用聚合物前体涂覆抗微生物剂然后用活性成分处理来制备微胶囊的方法。 本发明的另一个实施方案是通过将抗微生物剂与亲水性聚合物熔融混合,然后研磨成所需的粒度来制备微胶囊的方法。 还提供了包含微胶囊和基质聚合物的聚合物组合物。 本发明的另一个实施方案是由包含微胶囊和基质聚合物的聚合物组合物制备的制品。