公开(公告)号：US07038057B2

公开(公告)日：2006-05-02

申请号：US10482556

申请日：2002-08-13

Applicant: Gary David Annis ,  George Philip Lahm ,  Tom Paul Selby ,  Thomas Martin Stevenson

Inventor： Gary David Annis ,  George Philip Lahm ,  Tom Paul Selby ,  Thomas Martin Stevenson

IPC: C07D401/04 ,  A61K31/44

CPC classification number: C07D213/77 ,  A01N43/56 ,  C07C251/76 ,  C07C255/66 ,  C07D231/08 ,  C07D231/14 ,  C07D231/16 ,  C07D401/04 ,  C07D403/04 ,  C07D413/04 ,  C07D413/14

Abstract: This invention provides compounds of Formula (I), methods for their preparation and use for preparing compounds of Formula (II) wherein R1, R2, R3, R5, R6, X and n are as defined in the disclosure. This invention also discloses preparation of compounds of Formula (III) wherein R1, R2, R7, R8, R9 and n are as defined in the disclosure. This invention also pertains to certain compounds of Formula 4 and 6 used to prepare compounds of Formula (I), wherein R1, R2, R5, X and n are as defined in the disclosure

Abstract translation: 本发明提供了式（I）化合物，其制备方法和用于制备式（II）化合物的方法，其中R 1，R 2，R 3 R 5，R 6，X和n如本公开中所定义。 本发明还公开了制备式（III）的化合物，其中R 1，R 2，R 7，R 8， R 3，R 9和n如本公开所定义。 本发明还涉及用于制备式（I）化合物的式4和6的某些化合物，其中R 1，R 2，R 5， SUB，X和n如本公开中所定义

公开(公告)号：US5686393A

公开(公告)日：1997-11-11

申请号：US586797

申请日：1996-02-01

Applicant: George Philip Lahm ,  Thomas Martin Stevenson

Inventor： George Philip Lahm ,  Thomas Martin Stevenson

IPC: A01N20060101 ,  A01N43/74 ,  A01N43/76 ,  A01N55/00 ,  C07D20060101 ,  C07D263/10 ,  C07D263/14 ,  C07D277/10 ,  C07D413/10 ,  C07D417/10

CPC classification number: C07D263/10 ,  A01N43/74 ,  C07D263/14 ,  C07D277/10 ,  C07D413/10 ,  C07D417/10

Abstract: Described herein are arthropodicidal compounds, compositions and use of compounds of Formula (I) wherein the substituents are defined in the disclosure ##STR1##

Abstract translation: PCT No.PCT / US94 / 07459 Sec。 371日期：1996年2月1日 102（e）日期1996年2月1日PCT提交1994年7月29日PCT公布。 公开号WO95 / 04726 日期1995年2月16日描述的是式（I）化合物的节肢动物杀菌化合物，组合物和用途，其中取代基在本公开内容中定义

公开(公告)号：US20160317520A1

公开(公告)日：2016-11-03

申请号：US15207999

申请日：2016-07-12

Applicant: GEORGE PHILIP LAHM ,  JEFFREY KEITH LONG ,  MING XU

Inventor： GEORGE PHILIP LAHM ,  JEFFREY KEITH LONG ,  MING XU

IPC: A61K31/4439 ,  A61K31/42 ,  A01N43/80 ,  A61K9/00

CPC classification number: A61K31/4439 ,  A01N43/80 ,  A61K9/0019 ,  A61K9/0053 ,  A61K31/42

Abstract: Disclosed is a method for protecting an animal from a parasitic invertebrate pest comprising treating an animal orally or by injection with a pesticidally effective amount of a compound of Formula 1, wherein R1 is halogen, C1-C3 haloalkyl or C1-C3 haloalkoxy; R2 is H, halogen, C1-C3 alkyl, C1-C3 haloalkyl or cyano; R3 is H, halogen, C1-C3 haloalkyl or C1-C3 haloalkoxy; R4 is halogen, C1-C3 alkyl, C1-C3 haloalkyl or C1-C3 haloalkoxy; R5 is H, CH3, C2-C4 alkylcarbonyl, C2-C4 haloalkylcarbonyl, C2-C5 alkoxycarbonyl or CH2O(C1-C3 alkyl); R6 is C1-C6 alkyl, C1-C6 haloalkyl, C3-C6 cycloalkyl or C3-C6 halocycloalkyl, each group substituted with one R7; or R6 is (CH2)mQ; and Q, R7, R8a and R8b are as defined in the disclosure.

公开(公告)号：US08637552B2

公开(公告)日：2014-01-28

申请号：US13571677

申请日：2012-08-10

Applicant: Richard Alan Berger ,  Isaac Billy Annan ,  George Philip Lahm ,  John Lindsey Flexner ,  Thomas Paul Selby ,  Thomas Martin Stevenson

Inventor： Richard Alan Berger ,  Isaac Billy Annan ,  George Philip Lahm ,  John Lindsey Flexner ,  Thomas Paul Selby ,  Thomas Martin Stevenson

IPC: A01N43/40

CPC classification number: A01N43/56 ,  A01N43/54 ,  A01N43/58 ,  A01N43/86 ,  A01N25/24 ,  A01N25/10 ,  A01N2300/00

Abstract: This invention pertains to methods for protecting a propagule or a plant grown therefrom from invertebrate pests comprising contacting the propagule or the locus of the propagule with a biologically effective amount of a compound of Formula I, its N-oxide or an agriculturally suitable salt thereof wherein A and B and R1 through R8 are as defined in the disclosure. This invention also relates to propagules treated with a compound of Formula I and compositions comprising a Formula I compound for coating propagules.

Abstract translation: 本发明涉及用于保护繁殖体或从无脊椎动物害虫生长的植物的方法，包括使生殖有效量的式I化合物，其N-氧化物或农业上合适的盐使繁殖体的繁殖体或基因座接触，其中 A和B以及R 1至R 8如本公开中所定义。 本发明还涉及用式I化合物处理的繁殖体和包含用于包被繁殖体的式I化合物的组合物。

公开(公告)号：US08420673B2

公开(公告)日：2013-04-16

申请号：US12521156

申请日：2008-01-18

Applicant: Robert James Pasteris ,  George Philip Lahm

Inventor： Robert James Pasteris ,  George Philip Lahm

IPC: A61K31/4535 ,  C07D407/02

CPC classification number: C07D417/04 ,  A01N43/78 ,  C07D401/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14 ,  C07D417/14

Abstract: Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein R1, R2, A, G, W1, Q, X, Z, and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.

Abstract translation: 公开了式1的化合物，包括所有几何和立体异构体，N-氧化物及其盐，其中R 1，R 2，A，G，W 1，Q，X，Z和n如本公开所定义。 还公开了含有式1化合物的组合物和用于控制由真菌病原体引起的植物病害的方法，包括施用有效量的本发明化合物或组合物。

公开(公告)号：US20130029845A1

公开(公告)日：2013-01-31

申请号：US13561546

申请日：2012-07-30

Applicant: George Philip LAHM ,  Wesley Lawrence SHOOP ,  Ming XU

Inventor： George Philip LAHM ,  Wesley Lawrence SHOOP ,  Ming XU

IPC: A01N43/80 ,  A61K31/42 ,  C07D413/04 ,  A61K31/4439 ,  A01N43/40 ,  C07D413/14 ,  A61K31/4709 ,  A01N43/42 ,  A61K31/4725 ,  C07D417/14 ,  A01N63/02 ,  A01N25/00 ,  A01N63/04 ,  A01N43/16 ,  A01N57/16 ,  A01N43/78 ,  A01P7/04 ,  A01P7/00 ,  A61K35/76 ,  A61K35/74 ,  A61K9/00 ,  A61K31/675 ,  A61K31/426 ,  A61K31/7048 ,  A61P33/00 ,  A01C1/06 ,  A01M1/10 ,  A01M23/00 ,  C07D261/04

CPC classification number: A01N43/42 ,  A01M1/10 ,  A01M1/2005 ,  A01N43/80 ,  A61K9/1075 ,  A61K31/42 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/4709 ,  A61K31/4725 ,  A61K45/06 ,  C07D215/12 ,  C07D261/04 ,  C07D413/04 ,  C07D413/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14 ,  A61K2300/00

Abstract: Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein A1, A2, A3, A4, A5 and A6 are independently selected from the group consisting of CR3 and N; provided that at most 3 of A1, A2, A3, A4, A5 and A6 is N; B1, B2 and B3 are independently selected from the group consisting of CR2 and N; each R3 is independently H, halogen, C1-C6 alkyl, C1-C6 haloalkyl, C3-C6 cycloalkyl, C3-C6 halocycloalkyl, C1-C6 alkoxy, C1-C6 haloalkoxy, C1-C6 alkylthio, C1-C6 haloalkylthio, C1-C6 alkylsulfinyl, C1-C6 haloalkylsulfinyl, C1-C6 alkylsulfonyl, C1-C6 haloalkylsulfonyl, C1-C6 alkylamino, C2-C6 dialkylamino, —CN or —NO2; and R1, R2, R4, R5, W and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.

Abstract translation: 公开了式1的化合物，包括所有几何和立体异构体，N-氧化物及其盐，其中A1，A2，A3，A4，A5和A6独立地选自CR3和N; A1，A2，A3，A4，A5和A6中最多有3个为N; B1，B2和B3独立地选自CR2和N; 每个R 3独立地是H，卤素，C 1 -C 6烷基，C 1 -C 6卤代烷基，C 3 -C 6环烷基，C 3 -C 6卤代环烷基，C 1 -C 6烷氧基，C 1 -C 6卤代烷氧基，C 1 -C 6烷硫基，C 1 -C 6卤代烷硫基， C6烷基亚磺酰基，C1-C6卤代烷基亚磺酰基，C1-C6烷基磺酰基，C1-C6卤代烷基磺酰基，C1-C6烷基氨基，C2-C6二烷基氨基，-CN或-NO2; 并且R1，R2，R4，R5，W和n如本公开所定义。 还公开了含有式1化合物和控制无脊椎动物害虫的方法的组合物，包括使无脊椎害虫或其环境与生物有效量的本发明化合物或组合物接触。

公开(公告)号：US20130028879A1

公开(公告)日：2013-01-31

申请号：US13571852

申请日：2012-08-10

Applicant: GEORGE PHILIP LAHM ,  STEPHEN FREDERICK MCCANN ,  KANU MAGANBHAI PATEL ,  THOMAS PAUL SELBY ,  THOMAS MARTIN STEVENSON

Inventor： GEORGE PHILIP LAHM ,  STEPHEN FREDERICK MCCANN ,  KANU MAGANBHAI PATEL ,  THOMAS PAUL SELBY ,  THOMAS MARTIN STEVENSON

IPC: A01N43/56 ,  A01N43/54 ,  A01N43/60 ,  C07D265/22 ,  A01N63/04 ,  A01P7/04 ,  A01P7/00 ,  A01N43/40 ,  A01N63/00

CPC classification number: A01N43/56 ,  A01N43/54 ,  A01N43/58 ,  A01N43/86 ,  C07C251/76 ,  C07D213/77 ,  C07D231/06 ,  C07D231/08 ,  C07D231/14 ,  C07D231/16 ,  C07D401/04 ,  C07D413/04 ,  C07D413/14

Abstract: This invention pertains to a method for controlling lepidopteran, homopteran, hemipteran, thysanopteran and coleopteran insect pests comprising contacting the insects or their environment with an arthropodicidally effective amount of a compound of Formula I, its N-oxide or an agriculturally suitable salt thereof. wherein A and B and R1 through R8 are as defined in the disclosure.This invention further relates to a benzoxazinone compound of Formula 10 wherein R4 through R8 are as defined in the disclosure, useful for preparation of a compound of Formula I.

Abstract translation: 本发明涉及一种控制鳞翅目，同翅目，半扁桃，缨翅目和鞘翅目昆虫害虫的方法，包括使昆虫或其环境与节肢动物害虫有效量的式I化合物，其N-氧化物或农业上合适的盐接触。 其中A和B以及R 1至R 8如本公开所定义。 本发明还涉及式10的苯并恶嗪酮化合物，其中R 4至R 8如本公开所定义，可用于制备式I化合物。

公开(公告)号：US08231888B2

公开(公告)日：2012-07-31

申请号：US13156653

申请日：2011-06-09

Applicant: George Philip Lahm ,  Wesley Lawrence Shoop ,  Ming Xu

Inventor： George Philip Lahm ,  Wesley Lawrence Shoop ,  Ming Xu

IPC: C07D261/04 ,  C07D251/72 ,  C07D253/08 ,  C07D239/26 ,  C07D239/74 ,  C07D237/26 ,  C07D235/04 ,  C07D213/46 ,  C07D221/04 ,  A61K31/422 ,  A61K31/4439 ,  A61K31/4375 ,  A61K31/4709 ,  A61K31/47 ,  A01N25/02 ,  A01N25/08

CPC classification number: A01N43/42 ,  A01M1/10 ,  A01M1/2005 ,  A01N43/80 ,  A61K9/1075 ,  A61K31/42 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/4709 ,  A61K31/4725 ,  A61K45/06 ,  C07D215/12 ,  C07D261/04 ,  C07D413/04 ,  C07D413/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14 ,  A61K2300/00

Abstract: Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein A1, A2, A3, A4, A5 and A6 are independently selected from the group consisting of CR3 and N; provided that at most 3 of A1, A2, A3, A4, A5 and A6 is N; B1, B2 and B3 are independently selected from the group consisting of CR2 and N; each R3 is independently H, halogen, C1-C6 alkyl, C1-C6 haloalkyl, C3-C6 cycloalkyl, C3-C6 halocycloalkyl, C1-C6 alkoxy, C1-C6 haloalkoxy, C1-C6 alkylthio, C1-C6 haloalkylthio, C1-C6 alkylsulfinyl, C1-C6 haloalkylsulfinyl, C1-C6 alkylsulfonyl, C1-C6 haloalkylsulfonyl, C1-C6 alkylamino, C2-C6 dialkylamino, —CN or —NO2; and R1, R2, R4, R5, W and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.

Abstract translation: 公开了式1的化合物，包括所有几何和立体异构体，N-氧化物及其盐，其中A1，A2，A3，A4，A5和A6独立地选自CR3和N; A1，A2，A3，A4，A5和A6中最多有3个为N; B1，B2和B3独立地选自CR2和N; 每个R 3独立地为H，卤素，C 1 -C 6烷基，C 1 -C 6卤代烷基，C 3 -C 6环烷基，C 3 -C 6卤代环烷基，C 1 -C 6烷氧基，C 1 -C 6卤代烷氧基，C 1 -C 6烷硫基，C 1 -C 6卤代烷硫基， C6烷基亚磺酰基，C1-C6卤代烷基亚磺酰基，C1-C6烷基磺酰基，C1-C6卤代烷基磺酰基，C1-C6烷基氨基，C2-C6二烷基氨基，-CN或-NO2; 并且R1，R2，R4，R5，W和n如本公开所定义。 还公开了含有式1化合物和控制无脊椎动物害虫的方法的组合物，包括使无脊椎害虫或其环境与生物有效量的本发明化合物或组合物接触。

公开(公告)号：US20120122680A1

公开(公告)日：2012-05-17

申请号：US13386117

申请日：2010-08-03

Applicant: Caleb William Holyoke, JR. ,  Wenming Zhang ,  kanu Maganbhai Patel ,  George Philip Lahm ,  My-Hanh Thi Tong

Inventor： Caleb William Holyoke, JR. ,  Wenming Zhang ,  kanu Maganbhai Patel ,  George Philip Lahm ,  My-Hanh Thi Tong

IPC: A01N43/90 ,  A01C1/06 ,  C07D487/04 ,  C07D498/04 ,  C07D513/04 ,  A01P5/00 ,  A01N63/04 ,  A01N63/02 ,  A01P7/04 ,  A01P7/00 ,  A01P7/02 ,  C07D471/04 ,  A01N57/16

CPC classification number: C07D471/04 ,  A01N43/78 ,  A01N43/90 ,  C07D401/06 ,  C07D417/06 ,  C07D487/04 ,  C07D498/04 ,  C07D513/04

Abstract: Disclosed are compounds of Formula 1, N-oxides, and salts thereof, wherein X is O or S; Y is O or S; Z is a direct bond, O, S(O)n, NR6, C(R7)2O, OC(R7)2, C(═X1), C(═X1)E, EC(═X1), C(═NOR8) or C(═NN(R6)2); a is 0, 1, 2 or 3; and R1, R2, R3, R4, R5a, R5b, R6, R7, R8, X1 and E are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.

Abstract translation: 公开了式1的化合物，N-氧化物及其盐，其中X是O或S; Y为O或S; Z是直接键，O，S（O）n，NR6，C（R7）2O，OC（R7）2，C（= X1），C（= X1）E，EC（═X1），C NOR8）或C（= NN（R6）2）; a是0,1,2或3; 并且R1，R2，R3，R4，R5a，R5b，R6，R7，R8，X1和E如本公开所定义。 还公开了含有式1化合物和控制无脊椎动物害虫的方法的组合物，包括使无脊椎害虫或其环境与生物有效量的本发明化合物或组合物接触。

公开(公告)号：US20120114624A1

公开(公告)日：2012-05-10

申请号：US13264159

申请日：2010-05-04

Applicant: George Philip Lahm ,  Renee M. Lett ,  Brenton Todd Smith ,  Benjamin Kenneth Smith ,  C. Anne Daly

Inventor： George Philip Lahm ,  Renee M. Lett ,  Brenton Todd Smith ,  Benjamin Kenneth Smith ,  C. Anne Daly

IPC: A01N43/42 ,  A01N43/22 ,  A01N57/28 ,  A01N59/14 ,  A01P5/00 ,  A01N57/16 ,  A01N57/12 ,  A01N43/54 ,  A01N43/88 ,  A01N63/00 ,  C07D471/04 ,  A01N43/68

CPC classification number: A01N55/00 ,  A01N43/90

Abstract: Disclosed are compounds of Formula 1, N-oxides, and salts thereof, wherein Z is O or S; and R1, R2, R3, Q and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling a parasitic nematode comprising contacting the parasitic nematode or its environment with a biologically effective amount of a compound or a composition of the invention.

Abstract translation: 公开了式1，N-氧化物及其盐的化合物，其中Z为O或S; 并且R1，R2，R3，Q和n如本公开所定义。 还公开了含有式1化合物和控制寄生线虫的方法的组合物，其包括使寄生线虫或其环境与生物有效量的本发明化合物或组合物接触。