Method of detecting bio-molecules using the same field effect transistor on the gate sensing surface
    22.
    发明授权
    Method of detecting bio-molecules using the same field effect transistor on the gate sensing surface 有权
    使用栅极感应表面上相同的场效应晶体管检测生物分子的方法

    公开(公告)号:US07943970B2

    公开(公告)日:2011-05-17

    申请号:US11695886

    申请日:2007-04-03

    CPC classification number: G01N33/54373 G01N27/4145

    Abstract: Provided is a method of detecting the presence of a target bio-molecule or a concentration of the bio-molecule using a field effect transistor. The method includes: contacting a first sample having a first target bio-molecule with a reference electrode of a field effect transistor; measuring a first electric signal change of the field effect transistor; contacting a second sample with a sensing surface of the same field effect transistor; measuring a second electric signal change of the field effect transistor; and comparing the first electric signal with the second electric signal.

    Abstract translation: 提供了使用场效应晶体管检测目标生物分子的存在或生物分子的浓度的方法。 该方法包括:将具有第一目标生物分子的第一样品与场效应晶体管的参比电极接触; 测量场效应晶体管的第一电信号变化; 使第二样品与相同场效应晶体管的感测表面接触; 测量场效应晶体管的第二电信号变化; 以及将所述第一电信号与所述第二电信号进行比较。

    Apparatus and method for coding genetic information
    29.
    发明授权
    Apparatus and method for coding genetic information 有权
    用于编码遗传信息的装置和方法

    公开(公告)号:US07599800B2

    公开(公告)日:2009-10-06

    申请号:US11956570

    申请日:2007-12-14

    CPC classification number: G06F19/20 G06F19/22 G06F19/24 Y10S707/99943

    Abstract: Provided are an apparatus and a method for coding genetic information. An aligning unit aligns sample genetic information, wild-type probe genetic information, and mutant-type probe genetic information, based on a mutation position. A code storage unit stores first orthogonal codes assigned to each of bases located at left and right base regions based on the mutation position and second orthogonal codes assigned to a base located at the mutation position. A coding unit creates first code strings and second code strings. The first code strings are created by assigning the first orthogonal codes, sequentially from left to right, to the bases that make the aligned genetic information and adding a flag that represents the presence or absence of a corresponding base on the genetic information to the assigned first orthogonal codes, and the second code strings are created by assigning the second orthogonal codes to the base located at the mutation position and adding a flag that represents the type of the sample genetic information to the assigned second orthogonal codes.

    Abstract translation: 提供编码遗传信息的装置和方法。 对齐单元基于突变位置对准样品遗传信息,野生型探针遗传信息和突变型探针遗传信息。 代码存储单元基于所述突变位置和分配给位于所述突变位置的基站的第二正交码,存储分配给位于左侧和右侧基本区域的每个基站的第一正交码。 编码单元创建第一代码串和第二代码串。 第一代码串是通过从左到右依次分配第一正交码到创建对齐的遗传信息的基础,并将表示遗传信息上相应基础的存在或不存在的标志添加到所分配的第一个 通过将第二正交码分配给位于突变位置的基底,并将表示样本遗传信息的类型的标志加到所分配的第二正交码上而产生第二代码串。

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