公开(公告)号：US09927816B2

公开(公告)日：2018-03-27

申请号：US15153778

申请日：2016-05-13

Applicant: Macau University of Science and Technology

Inventor： Zhiwu Li ,  Oussama Karoui ,  Anis Koubaa ,  Mohamed Khalgui ,  Emna Guerfala ,  Eduardo Tovard ,  Naiqi Wu

IPC: G05D1/02 ,  G05D1/00

CPC classification number: G05D1/0295 ,  B60K31/00 ,  B60W30/14 ,  G05D1/0027 ,  G05D1/0212 ,  G05D1/0278 ,  G05D2201/0213 ,  G08G1/22

Abstract: A method for operating a follower vehicle in a vehicle platoon includes determining, during operation, whether the follower vehicle is operating in a normal state or an abnormal state based on an operation condition of a component of the follower vehicle, or a communication between the follower vehicle and a preceding vehicle in the vehicle platoon. The method further includes selecting a first control mode if the follower vehicle is in the normal state and a second control mode if the follower vehicle is in the abnormal state so as to control movement of the follower vehicle using the selected control mode. In the first control mode, the follower vehicle uses communication data received from the preceding vehicle in the vehicle platoon to control its movement. In the second control mode, the follower vehicle uses data obtained by one or more of its sensors to control its movement.

公开(公告)号：US20170329925A1

公开(公告)日：2017-11-16

申请号：US15150580

申请日：2016-05-10

Applicant: Macau University of Science and Technology

Inventor： Yong Liang ,  Hua Chai ,  Zi-yi Yang ,  Xiao-Ying Liu

IPC: G06F19/00 ,  G06F17/18

CPC classification number: G16H50/50 ,  Y02A90/26

Abstract: A system and a method for determining an estimated survival time of a subject with a medical condition utilizes the novel RS-AFT model and is especially suitable and highly advantageous for survival analysis based on microarray gene expression data because of its exceptional performance of gene selection, stable noise resistance, and high prediction precision.

公开(公告)号：US20170329913A1

公开(公告)日：2017-11-16

申请号：US15150732

申请日：2016-05-10

Applicant: Macau University of Science and Technology

Inventor： Yong Liang ,  Hai-Hui Huang ,  Xiao-Ying Liu

IPC: G06F19/00 ,  G06N7/00

Abstract: A method and a system for determining an association of at least one biological feature with a medical condition utilizes the novel L1/2 penalized network-constraint regression model to achieve an improved biological analysis, in particular by solving high-dimensional problems. The method and the system of the present invention attain high accuracy and preciseness.

公开(公告)号：US20170329912A1

公开(公告)日：2017-11-16

申请号：US15150608

申请日：2016-05-10

Applicant: Macau University of Science and Technology

Inventor： Yong Liang ,  Hai-Hui Huang ,  Xiao-Ying Liu

IPC: G06F19/00 ,  G06N5/02

CPC classification number: G16H50/20 ,  G06N5/02 ,  G06N7/023 ,  G06N20/00

Abstract: A system and a method for determining an association of one or more biological features with a medical condition provides empirical results and simulations confirming that the involvement of both L1/2-regularized logistic regression and L2-regularized logistic regression in the regression model is highly competitive against usual approaches like Lasso, L1/2, SCAD-L2, and Elastic net in analyzing high dimensional and low sample sizes data.

公开(公告)号：US20170281702A1

公开(公告)日：2017-10-05

申请号：US15089687

申请日：2016-04-04

Applicant: Macau University of Science and Technology

Inventor： Jing-Rong Wang ,  Zhi-Hong Jiang ,  Qi-Tong Feng ,  Guo-Yuan Zhu ,  Wei-Na Gao ,  Zifeng Yang ,  Nanshan Zhong

IPC: A61K36/19 ,  A61K31/7056 ,  A61K31/192 ,  A61K31/404 ,  A61K31/047 ,  A61K31/191 ,  A61K31/538 ,  A61K31/517

CPC classification number: A61K36/19 ,  A61K31/404 ,  A61K31/538 ,  A61K31/567 ,  A61K2236/15 ,  A61K2236/17 ,  A61K2236/33 ,  A61K2236/55

Abstract: The present invention provides a method of isolating at least one ingredient with anti-viral efficacy from Baphicacanthus cusia. The ingredient can be an alkaloid, a triterpenoid, a lignan, a phenylethanoid, a sesquiterpene lactone, or a flavonoid. Two new alkaloids are produced, which have not been previously reported. Moreover, the method isolates 12 compounds which could not or have not been previously isolated. A pharmaceutical composition includes the at least one ingredient and at least one pharmaceutical tolerable excipient. A method of treating a subject suffering from a viral disease includes administering at least one ingredient isolated from Baphicacanthus cusia.

公开(公告)号：US20170279298A1

公开(公告)日：2017-09-28

申请号：US15078367

申请日：2016-03-23

Applicant: Macau University of Science and Technology

Inventor： Zhiwu Li ,  Zhongyuan Jiang ,  Naiqi Wu ,  Mengchu Zhou

IPC: H02J9/06 ,  G01R31/40

CPC classification number: H02J9/06 ,  G01R31/40 ,  H02J3/28 ,  H02J13/001 ,  H02J2003/007 ,  Y02E60/722 ,  Y02E60/723 ,  Y02E60/76 ,  Y04S10/14 ,  Y04S10/16 ,  Y04S10/40 ,  Y04S40/22

Abstract: A power transmission system includes a plurality of electrical substations and a plurality of transmission lines arranged to connect the plurality of electrical substations to form a power transmission network; and a controller system arranged to control a power transmission within the power transmission network. The controller system includes: a detection module arranged to detect an occurrence of a fault in at least one faulty electrical substation of the plurality of electrical substations; and a restoration module arranged to at least temporally maintain an output power of the at least one faulty electrical substation; and wherein at least one of the plurality of electrical substations is operable to facilitate maintaining of the output of the at least one faulty electrical substation upon the detection of the occurrence of the fault.

公开(公告)号：US09769849B2

公开(公告)日：2017-09-19

申请号：US14840139

申请日：2015-08-31

Applicant: Macau University of Science and Technology

Inventor： Li Feng

IPC: H04J3/16 ,  H04L12/42 ,  H04W74/08 ,  H04W84/12

CPC classification number: H04W74/0816 ,  H04W84/12

Abstract: A method for enabling one or more nodes to communicate with an access point (AP) according to a CSMA/CA protocol is provided. In one embodiment of the method, when the individual node enters into a state of having at least one packet of data to be transmitted to the AP, the individual node waits for a non-zero deterministic delay so that any packet arrived during the delay is allowed to be aggregated and transmitted upon one transmission opportunity, thereby improving channel utilization. The delay is determined such that a predicted system throughput is maximized. It is found that the system throughput is significantly affected by the relationship between the delay and the number of the one or more nodes. Hence, the delay is advantageously determined according to the number of the one or more nodes. After the delay expires, the individual node initiates a contending procedure.

公开(公告)号：US09744145B1

公开(公告)日：2017-08-29

申请号：US15406798

申请日：2017-01-16

Applicant: Macau University of Science and Technology

Inventor： Liang Liu ,  Lai-Han Elaine Leung ,  Xiao-Jun Yao ,  Run-Ze Li

IPC: A61K31/18

CPC classification number: A61K31/18

Abstract: This invention provides a method of treating lung cancer including administering a therapeutically effective amount of a compound of 0089-0022 formula I to a subject in need thereof. The compound activates pyruvate kinase M2 isoform (PKM2) to treat the lung cancer. In one example, the lung cancer is Non-Small Cell Lung Cancer (NSCLC).

公开(公告)号：US20170135979A1

公开(公告)日：2017-05-18

申请号：US14940406

申请日：2015-11-13

Applicant: Macau University of Science and Technology

Inventor： Xiao Jun Yao ,  Lai Han Leung ,  Lian Xiang Luo ,  Liang Liu

IPC: A61K31/343

CPC classification number: A61K31/343

Abstract: The present invention relates to the administration of a novel compound advantageously efficacious as PDEδ inhibitor and its effects on subjects with cancer. More specifically, the present invention is directed to a method for administering a compound having favorable geometric properties for interacting with the PDEδ prenyl-binding pocket, namely has certain structural components such as a three-cyclic backbone and at least one benzoyl-moiety in a side chain having at least two substituents containing highly electronegative atoms and being linked to the backbone via an aliphatic chain, for treating a subject suffering from a disease such as cancer, in particular non-small-cell lung cancer. The presence of said structural components particularly contributes to an advantageous interaction with PDEδ, in particular with amino acids deep in the binding pocket. The present invention further provides a method to target tumor cells harboring an RAS gene mutation as well as pharmaceutical compositions comprising said compound.

公开(公告)号：US20170131700A1

公开(公告)日：2017-05-11

申请号：US14942031

申请日：2015-11-16

Applicant: Macau University of Science and Technology

Inventor： Zhiwu Li ,  Lei Feng ,  Huimin Zhang ,  Naiqi Wu

IPC: G05B19/10

Abstract: A method for implementing a new reactive system and a new reactive system includes applying at least one input suitable for the new reactive system to an existing reactive system to obtain at least one output produced by the existing reactive system; comparing the at least one output with an expected output representative of an output expected to be obtained by applying the at least one input to the new reactive system; determining if the at least one output would be compatible with the expected output; and using the compatibility between the at least one output and the expected output to generate a supervisory control rule set arranged for supervisory control of the existing reactive system when used as part or whole of the new reactive system.