Abstract:
An exemplary embodiment is related to a method of using an adhesion precursor in an integrated circuit fabrication process. The method includes providing a gas of material over a dielectric material and providing a copper layer over an adhesion precursor layer. The adhesion precursor layer is formed by the gas, and the dielectric material includes an aperture.
Abstract:
A suturing instrument and method for placing mattress stitches in soft tissues is described. An elongate shaft with a stationary jaw and a moveable jaw disposed at the distal end is coupled to a handle grip at the proximal end configured to manipulate the jaws into open and closed positions. The jaws are configured to allow for atraumatic grasping of soft tissues. The stationary jaw is comprised of a serrated face incorporating apertures through which needles attached to opposite ends of a single strand of suture material may be driven out into and through grasped tissue. The serrated upper jaw is configured with needle catch adapted to accept and capture the needles and suture. The handle is released to open the moveable jaw, the instrument may be withdrawn, trailing the suture, and leaving a mattress stitch in the grasped tissue.
Abstract:
Methods and compounds are provided for detecting target molecules in a sample using specific binding assays. In particular, methods are provided for detecting a nucleic acid target in a sample. In one embodiment, the method comprises hybridizing a nucleic acid target, comprising a target nucleic acid sequence, to a nucleic acid probe, comprising a probe nucleic acid sequence, wherein the target comprises a binding ligand. The hydridized target is contacted with a receptor comprising multiple sites capable of binding the binding ligand to complex the receptor to the binding ligand, and the receptor is contacted with an amplification reagent, comprising a plurality of the binding ligands, to complex the amplification reagent to the receptor. The presence of the complexed amplification reagent then is detected, for example, by detecting the presence of a detectable label, such as a fluorescent label, for example, on the receptor or the amplification reagent. Optionally, the amplification reagent, comprising a plurality of the binding ligands, is contacted with labeled receptor molecules thereby to complex a plurality of labeled receptor molecules to the amplification reagent, and the labeled receptor molecules complexed to the amplification reagent are detected. This permits the detectable signal to be enhanced and amplified. In one embodiment, the binding ligand is biotin, the receptor is streptavidin, and the amplification reagent is an antibody or a DNA matrix. In another embodiment, an array of different nucleic acid probes immobilized on a surface, each having a defined sequence and location on the surface, may be used in the assays, thus permitting screening and detection of binding of a large number of nucleic acids.
Abstract:
A system and method for isolating a problem in a network. Upon a report of error activity in a first signal transport level, a first layer in the network management system uses performance data to identify the highest signal transport level that exhibits simultaneous error activity. The first layer attempts to isolate the problem if it determines that it has access to enough information.
Abstract:
A radio frequency generator has first and second lasers configured to emit first and second optical outputs; a reference module configured to receive at least part of the first and second optical outputs from the first and second lasers; a control module connected to the first and second lasers and to the reference module; and an optical-to-electrical (O/E) converter configured to process optical signals, originating from the first and second single-frequency lasers, to provide a radio frequency output. Another radio frequency generator has a control module; and a reference module connected to the control module. The reference module includes a photonic integrated circuit (PIC) having first and second single-frequency lasers configured to emit first and second optical outputs; an unbalanced Mach-Zehnder interferometer (UMZI) with first and second 3×3 optical splitter/combiners; first and second peripheral splitter/combiners; and an output splitter/combiner.
Abstract:
A device has first, second and third elements fabricated on a common substrate. The first element supports a first optical mode in a first active waveguide, the second element supports a second optical mode in a second passive waveguide, and the third element, at least partly butt-coupled to the first element, has a bottom waveguide, supporting a bottom intermediate mode, overlying a top waveguide, supporting a top intermediate mode. A tapered waveguide structure in the top waveguide facilitates efficient adiabatic transformation between the top intermediate mode and the bottom intermediate mode. Tapering in at least one of the bottom waveguide and the second waveguide facilitates efficient adiabatic transformation between the second optical mode and the bottom intermediate optical mode. No adiabatic transformation occurs between either of the intermediate optical modes and the first optical mode. Lithographic alignment marks facilitate precise alignment of the three elements during device fabrication.
Abstract:
A device includes a first element having a passive waveguide structure supporting a first optical mode, a second element providing heat spreading functionality, a third element thermally coupled to the second element, having an active waveguide structure supporting a second optical mode, and a fourth element, at least partly butt-coupled to the third element, having an intermediate waveguide structure supporting intermediate optical modes. A tapered waveguide structure in either one of the first and fourth elements facilitates efficient adiabatic transformation between the first optical mode and one of the intermediate optical modes. No adiabatic transformation occurs between any of the intermediate optical modes and the second optical mode. Mutual alignments of the first, second, third and fourth elements are defined using lithographic alignment marks that facilitate precise alignment between layers formed during processing steps of fabricating the first, second, third and fourth elements.
Abstract:
A device includes three elements fabricated on a common substrate. The first element includes an active waveguide structure having at least three sub-layers supporting a first optical mode. The second element has a passive waveguide structure supporting a second optical mode, and the third element, butt-coupled to the first element, has an intermediate waveguide structure supporting intermediate optical modes. One sub-layer in the active waveguide structure includes an n-contact layer, another sub-layer includes a p-contact layer, and a third sub-layer includes an active region. A tapered waveguide structure in at least one of the second and third elements facilitates efficient adiabatic transformation between the second optical mode and an intermediate optical mode. No adiabatic transformation occurs between that intermediate optical mode and the first optical mode. Mutual alignments of the three elements are defined using lithographic alignment marks that facilitate precise alignment between layers formed fabrication of the elements.
Abstract:
A device providing efficient transformation between an initial optical mode and a second optical mode includes first, second and third elements fabricated on a common substrate. The first element includes first and second active sub-layers supporting initial and final optical modes with efficient mode transformation therebetween. The second element includes a passive waveguide structure supporting a second optical mode. The third element, at least partly butt-coupled to the first element, includes an intermediate waveguide structure supporting an intermediate optical mode. If the final optical mode differs from the second optical mode by more than a predetermined amount, a tapered waveguide structure in the second or third elements facilitates efficient transformation between the intermediate optical mode and the second optical mode. Precise alignment of sub-elements formed in one of the elements, relative to sub-elements formed in another one of the elements, is defined using lithographic alignment marks.
Abstract:
A device comprises first, second and third elements fabricated on a common substrate. The first element comprises an active waveguide structure comprising: one portion, of effective cross-sectional area A1, supporting a first optical mode; and a second portion, butt-coupled to the first portion, of effective cross-sectional area A2>A1. The second element comprises a passive waveguide structure supporting a second optical mode. The third element, at least partly butt-coupled to the second portion, comprises an intermediate waveguide structure supporting intermediate optical modes. If the first optical mode differs from the second optical mode by more than a predetermined amount, a tapered waveguide structure in at least one of the second and third elements facilitates efficient adiabatic transformation between the first optical mode and one intermediate optical mode. No adiabatic transformation occurs between any intermediate optical mode and the first optical mode. Mutual alignments of the elements are defined using lithographic marks.