公开(公告)号：US20030159180A1

公开(公告)日：2003-08-21

申请号：US10059911

申请日：2002-01-28

Applicant: REGENTS OF THE UNIVERSITY OF CALIFORNIA, Office of Technology Transfer

Inventor： Robert L. Fischer ,  Yukiko Mizukami

IPC: A01H001/00 ,  C12N015/82

CPC classification number: C12N15/8261 ,  C12N15/8289 ,  Y02A40/146

Abstract: The invention provides methods of altering organ mass, controlling fertility and enhancing asexual reproduction in plants through the modulation of plant growth and cell proliferation. The methods involve producing transgenic plants comprising a recombinant expression cassette containing a modified ANT nucleic acid linked to a plant promoter.

公开(公告)号：US11116405B2

公开(公告)日：2021-09-14

申请号：US14390181

申请日：2013-04-09

Applicant: Profound Medical Inc. ,  THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF HEALTH & HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH, OFFICE OF TECHNOLOGY TRANSFER

Inventor： Ari Ilkka Mikael Partanen ,  Matthew Robert Dreher ,  Pavel Sergeyevich Yarmolenko ,  Bradford Johns Wood ,  Elma Natalia Carvajal Gallardo

IPC: A61B5/00 ,  A61N7/02 ,  A61B34/10 ,  A61B5/01 ,  A61B5/055 ,  A61N7/00 ,  A61B18/00 ,  A61B17/00 ,  A61B90/00

Abstract: The invention provides for a medical instrument (200) comprising a magnetic resonance imaging system (202) and a high-intensity focused ultrasound system (204) with an electronically controllable and a mechanically controllable focus. Execution of instructions by a processor (244) controlling the instrument cause the processor to: receive (100) a target zone (240, 264) descriptive of a zone within the subject; divide (102) the target zone into multiple sub-zones (416, 418, 420, 422, 424, 426, 428, 430, 432, 434); determine (104) a sequence (272) for moving the transducer position to each of the multiple sub-zones; determine (106) a selected sub-zone selected from the multiple sub-zones using the sequence; repeatedly control (108) the mechanical positioning system to move the transducer to the transducer position of the selected sub-zone; repeatedly acquire (110) the magnetic resonance thermometry data; repeatedly determine (112) a temperature property map (274); repeatedly heat (114) the regions independently to the target temperature by controlling the electronically controlled focus with a temperature feedback algorithm (286); and repeatedly change (116) the selected sub-zone using the sequence.

公开(公告)号：US20160131724A1

公开(公告)日：2016-05-12

申请号：US14899480

申请日：2014-06-19

Applicant: OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTES OF HEALTH

Inventor： Robert S. Balaban ,  Robert J. Lederman ,  Michael Hansen ,  Anthony Faranesh ,  Kanishka Ratnayaka

IPC: G01R33/31 ,  A61B5/055

CPC classification number: G01R33/31 ,  A61B5/055 ,  A61B2503/04 ,  A61B2503/06 ,  G01R33/28 ,  G01R33/3804

Abstract: A bore covering for sealing an MRI scanner bore to create a controlled environment within the MRI scanner bore is disclosed. The bore coverings used with climate control devices may create an incubator-like environment to allow for improved preparation, control, and imaging of infants. A system and kit including one or more bore coverings, and a method of using the bore coverings to create a controlled environment within the MRI scanner bore are also described.

Abstract translation: 公开了一种用于密封MRI扫描器孔以在MRI扫描器孔内形成受控环境的孔盖。 与气候控制装置一起使用的孔罩可能产生类似孵化器的环境，以便改进婴儿的准备，控制和成像。 还描述了包括一个或多个孔覆盖物的系统和试剂盒，以及使用孔覆盖物在MRI扫描器孔内产生受控环境的方法。

公开(公告)号：US20130188409A1

公开(公告)日：2013-07-25

申请号：US13747166

申请日：2013-01-22

Applicant: University of Rochester, Office of Technology Transfer

Inventor： Tolga Soyata

IPC: G11C15/00

CPC classification number: G11C15/00 ,  G11C15/04

Abstract: An energy-efficient CAM architecture provides increased speed of searching, reduced power consumption, or a tuned combination of increased speed of searching and reduced power consumption. The CAM comprises a plurality of CAM banks, a plurality of Bloom filters, each Bloom filter associated with a content addressable memory bank, each Bloom filter recording elements inserted into an associated content addressable memory bank, wherein the size of each Bloom filter is configured to reduce energy or power consumption of the content addressable memory apparatus. The size of each Bloom filter may be configured to reduce energy or power consumption of the content addressable memory apparatus.

Abstract translation: 高能效的CAM架构提供了更高的搜索速度，降低了功耗，或者提高了搜索速度和降低功耗的调整组合。 CAM包括多个CAM组，多个Bloom过滤器，每个Bloom过滤器与内容可寻址存储体相关联，每个Bloom过滤器记录元件插入到相关联的内容可寻址存储体中，其中每个Bloom过滤器的大小被配置为 降低内容可寻址存储装置的能量或功率消耗。 每个布隆过滤器的尺寸可以被配置为减少内容可寻址存储器设备的能量或功率消耗。

公开(公告)号：US20040253123A1

公开(公告)日：2004-12-16

申请号：US10757973

申请日：2004-01-13

Applicant: California Institute of Technology ,  Office of Technology Transfer M/C 210-85, Cal Tech

Inventor： Jun Xie ,  Jason Shih ,  Yu-Chong Tai

IPC: F04F011/00 ,  F04B001/00 ,  F04B037/02 ,  F04B017/00

CPC classification number: B81C1/00119 ,  B81B2201/036 ,  B81B2203/0127 ,  B81B2203/0338 ,  F04B43/043 ,  F04B43/082 ,  F04B43/12 ,  Y10T137/87692

Abstract: An electrostatic fluid regulating device and methods. The device has a substrate. The device also has a first electrode coupled to the substrate. The device has a polymer based diaphragm. A second electrode is coupled to the diaphragm. A polymer based fluid chamber is coupled to the diaphragm. The device also has an inlet coupled to the polymer based fluid chamber and an outlet coupled to the polymer based fluid chamber.

Abstract translation: 一种静电流体调节装置及方法。 该装置具有基板。 该器件还具有耦合到衬底的第一电极。 该装置具有基于聚合物的隔膜。 第二电极耦合到隔膜。 基于聚合物的流体室耦合到隔膜。 该装置还具有连接到基于聚合物的流体室的入口和连接到基于聚合物的流体室的出口。

公开(公告)号：US20030237121P1

公开(公告)日：2003-12-25

申请号：US10177479

申请日：2002-06-20

Applicant: Regents of the University of California Office of Technology Transfer University of California

Inventor： Mikeal L. Roose ,  Timothy A. Williams ,  Robert K. Soost ,  James W. Cameron

IPC: A01H005/00

CPC classification number: A01H6/78 ,  A01H5/08

Abstract: A new mandarin hybrid called nullTDE3null is distinguished by production of fruit that combine mid-season maturity, medium large fruit size, attractive deep orange rind color and virtual absence of seeds with rich fruit flavor.

Abstract translation: 名为“TDE3”的新型普通话混合物的特征在于水果的生产，结合中期成熟度，中等大果实，有吸引力的深橙色皮肤颜色和虚拟缺乏具有丰富水果味道的种子。

公开(公告)号：US20030186853A1

公开(公告)日：2003-10-02

申请号：US10106588

申请日：2002-03-25

Applicant: The Regents of the University of California, Office of Technology Transfer

Inventor： Edward T. Wei ,  Kurt W. Carlson

IPC: A61K038/24 ,  C07K014/575

CPC classification number: C07K14/57509 ,  A61K38/00 ,  Y10S930/27

Abstract: This invention provides novel members of the corticiotropin-releasing hormone superfamily and analogs thereof wherein the 38th amino acid from the N-terminus is DnullNle, i.e. nullDnullNle38nullnullCRH peptide.

Abstract translation: 本发明提供了促肾上腺皮质激素释放激素超家族及其类似物的新成员，其中N末端的38个氨基酸是D-Nle，即[D-Nle 38] -CRH肽。

公开(公告)号：US20020166139A1

公开(公告)日：2002-11-07

申请号：US10098306

申请日：2002-03-15

Applicant: The Regents of the University of California Office of Technology Transfer

Inventor： Girdhar K. Pandey ,  Rajeev Gupta ,  Kyung-Nam Kim ,  Sheng Luan

IPC: A01H001/00 ,  A01H005/00

CPC classification number: C12N15/8273 ,  C07K14/415

Abstract: The invention provides novel methods useful for enhancing a stress response in plants. Specifically, the methods of the present invention are useful for increasing the tolerance of a plant to stresses such as hyperthermia, hypothermia, hyperosmolarity, hypoosmolarity, and wounds.

Abstract translation: 本发明提供了用于增强植物胁迫反应的新颖方法。 具体地，本发明的方法可用于增加植物对诸如高热，低体温，高渗透压，低渗性和伤口之类的胁迫的耐受性。

公开(公告)号：US20020154535A1

公开(公告)日：2002-10-24

申请号：US10053814

申请日：2002-01-18

Applicant: The Regents of the University of California Office of Technology Transfer

Inventor： David F. Bocian ,  Werner G. Kuhr ,  Jonathan Lindsey

IPC: G11C011/00

CPC classification number: H01L51/0078 ,  B82Y10/00 ,  C07D487/22 ,  C07D519/00 ,  C07F17/02 ,  G11B9/14 ,  G11B9/149 ,  G11C11/5664 ,  G11C13/0009 ,  G11C13/0014 ,  G11C13/0016 ,  G11C2213/15 ,  G11C2213/77 ,  H01L27/28 ,  H01L51/0077 ,  H01L51/0084 ,  H01L51/009 ,  H01L51/0595 ,  Y10S977/943

Abstract: This invention provides novel high density memory devices that are electrically addressable permitting effective reading and writing, that provide a high memory density (e.g., 1015 bits/cm3), that provide a high degree of fault tolerance, and that are amenable to efficient chemical synthesis and chip fabrication. The devices are intrinsically latchable, defect tolerant, and support destructive or non-destructive read cycles. In a preferred embodiment, the device comprises a fixed electrode electrically coupled to a storage medium having a multiplicity of different and distinguishable oxidation states wherein data is stored in said oxidation states by the addition or withdrawal of one or more electrons from said storage medium via the electrically coupled electrode.

公开(公告)号：US12268512B2

公开(公告)日：2025-04-08

申请号：US18135738

申请日：2023-04-18

Applicant: Galiana Technology Inc. ,  National Institutes of Health, Office of Technology Transfer

Inventor： Bruce T Hope ,  Mark A Wells ,  Gregory D Sutton

IPC: A61B5/00 ,  A61B5/07 ,  A61B5/145 ,  A61B5/1473

Abstract: An intracellular monitoring device (IMD) that fits completely inside a living cell, and causes no significant impairment, to a cell's normal biological processes. The IMD monitors a cell for its level of a biological substance (e.g., calcium ion concentration) of interest. If the biological substance reaches or exceeds a threshold, the IMD transmits an electromagnetic signal, received by an antenna outside the cell. Each IMD has its electromagnetic signal encoded with a unique frequency. Detection of the frequency components, in the signals received by an antenna, permits identification of the source IMD's. A high calcium ion concentration is indicative of a strongly-activated cerebral cortex neuron. Brain tissue is relatively transparent to near infrared, making it a good frequency band, for the electromagnetic signals from neuron-monitoring IMD's. The near infrared of each IMD can be produced by quantum dots, powered by bioelectric catalysis triggered by high calcium ion concentration.