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公开(公告)号:US08057994B2
公开(公告)日:2011-11-15
申请号:US11178045
申请日:2005-07-08
申请人: Martin Bill , Ricky Paul Young
发明人: Martin Bill , Ricky Paul Young
CPC分类号: G06F19/22
摘要: A method of investigating a DNA sample is provided involving taking at least two sub-samples from the sample, amplifying the sub-samples, analyzing the sub-samples to obtain identity information and amount of that identity about one or more alleles indicated as present in the sub-samples in respect of 5 or more loci and establishing identity information deemed representative of the sample from the sub-samples, wherein identity information from a sub-sample about a particular identity is included in the identity information deemed representative of the sample when that particular identity is indicated as present by one or more of the sub-samples analyzed, the amount of that particular identity in the identity information deemed representative of the sample being a weighted combination based on the amount of that particular identity in the sub-samples. In this way useful profiles can be obtained more often than they are at present, with reduced costs and with reduced expertise and time requirements.
摘要翻译: 提供了一种研究DNA样品的方法,其涉及从样品中取出至少两个亚样品,扩增子样品,分析亚样品以获得关于一个或多个等位基因的身份信息和数量, 关于5个或更多个位点的子样本,并建立认为代表来自子样本的样本的身份信息,其中来自子样本的关于特定身份的身份信息被包括在被认为代表样本的身份信息中 该特定身份由所分析的一个或多个子样本表示,认为代表样本的身份信息中的该特定身份的数量是基于子样本中该特定身份的量的加权组合 。 以这种方式,可以比现在更有效地获得有用的配置文件,降低成本,减少专业知识和时间要求。
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公开(公告)号:US20110262785A1
公开(公告)日:2011-10-27
申请号:US13092690
申请日:2011-04-22
IPC分类号: H01M10/42
CPC分类号: H01M2/1077 , H01M2/1083 , H01M2/206 , H01M10/0565
摘要: A battery module that includes a battery unit composed of a plurality of flat cells and having an end face, a container with an end piece that encloses the battery unit, and a damping assembly disposed between the end face and the end piece. The damping assembly includes a pressure plate, coupled to the end face, that distributes a force substantially equally over the end face. The damping assembly further includes a damping mechanism that damps battery unit oscillations within the container and applies the force to the pressure plate. Coupling the end plate to the damping mechanism compresses the damping mechanism, and causes the damping mechanism to exert a reactionary force against the pressure plate. Furthermore, the damping assembly compresses and substantially suspends the battery unit within the container, such that one face of the battery unit does not substantially contact the container interior.
摘要翻译: 一种电池模块,包括由多个扁平电池组成并具有端面的电池单元,具有封闭所述电池单元的端部的容器以及设置在所述端面与所述端件之间的阻尼组件。 阻尼组件包括联接到端面的压板,其在端面上基本相等地分配力。 阻尼组件还包括阻尼机构,其阻止容器内的电池单元振荡并将力施加到压力板。 将端板耦合到阻尼机构,压缩阻尼机构,并使阻尼机构对压板施加反作用力。 此外,阻尼组件将电池单元压缩并基本上悬挂在容器内,使得电池单元的一个面基本上不接触容器内部。
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公开(公告)号:US20100124306A1
公开(公告)日:2010-05-20
申请号:US12272215
申请日:2008-11-17
申请人: Eric Paul Young
发明人: Eric Paul Young
摘要: A nuclear reactor module includes a reactor core and a reactor housing that surrounds the reactor core about its sides, wherein the reactor housing is configured to direct coolant through the reactor core. A neutron reflector is located between the reactor core and the reactor housing, wherein the neutron reflector has a plurality of inlet ports facing the reactor core. The neutron reflector also has a plurality of outlet ports fluidly connected to the inlet ports to direct a portion of the coolant through the neutron reflector.
摘要翻译: 核反应堆模块包括反应堆堆芯和反应堆壳体围绕反应堆核心围绕其侧面,其中反应器壳体构造成引导冷却剂通过反应堆堆芯。 中子反射器位于反应堆堆芯和反应器壳体之间,其中中子反射器具有面向反应堆芯的多个入口。 中子反射器还具有流体地连接到入口端口的多个出口端口,以引导冷却剂的一部分通过中子反射器。
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公开(公告)号:US20100124303A1
公开(公告)日:2010-05-20
申请号:US12272175
申请日:2008-11-17
IPC分类号: G21C9/00
摘要: A nuclear reactor module includes a reactor vessel and a reactor housing mounted inside the reactor vessel, wherein the reactor housing comprises a shroud and a riser located above the shroud. The nuclear reactor module further includes a heat exchanger proximately located about the riser, and a reactor core located in the shroud. A steam generator by-pass system is configured to provide an auxiliary flow path of primary coolant to the reactor core to augment a primary flow path of the primary coolant out of the riser and into the shroud, wherein the auxiliary flow path of primary coolant exits the reactor housing without passing by the heat exchanger.
摘要翻译: 核反应堆模块包括安装在反应堆容器内的反应堆容器和反应器壳体,其中反应器壳体包括护罩和位于护罩上方的立管。 核反应堆模块还包括围绕提升管邻近设置的热交换器和位于护罩中的反应堆堆芯。 蒸汽发生器旁路系统被配置为提供主冷却剂到反应堆堆芯的辅助流动路径,以将主冷却剂的主流动路径提升出提升管并进入护罩,其中初级冷却剂的辅助流动路径流出 反应器壳体不经过热交换器。
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公开(公告)号:US20090036429A1
公开(公告)日:2009-02-05
申请号:US12224109
申请日:2007-02-16
申请人: Norman E. Ohler , Jeffrey W. Watthey , Qin Zong , Paul Young , Kathryn J. Strand
发明人: Norman E. Ohler , Jeffrey W. Watthey , Qin Zong , Paul Young , Kathryn J. Strand
IPC分类号: A61K31/4545 , A61P35/00 , A61P9/00 , A61P19/00 , A61P29/00 , C07D401/14 , C07D401/12 , A61K31/454 , C07D413/12 , C07D211/42 , A61K31/55 , A61K31/496 , A61K31/517
CPC分类号: C07D211/46 , C07D211/42 , C07D401/06 , C07D401/12 , C07D405/06 , C07D405/12 , C07D409/06 , C07D409/12 , C07D413/06
摘要: Chemical agents, such as derivatives of hydroxypiperidine moieties, and similar heterocyclic ring structures, including salts thereof, that act as anti-cancer and anti-tumor agents, especially where such agents modulate the activity of enzymes and structural polypeptides present in cells, such as cancer cells, or where the agents modulate levels of gene expression in cellular systems, including cancer cells, are disclosed, along with methods for preparing such agents, as well as pharmaceutical compositions containing such agents as active ingredients and methods of using these as therapeutic agents.
摘要翻译: 化学试剂,例如羟基哌啶部分的衍生物,以及类似的杂环结构,包括其盐,其作为抗癌剂和抗肿瘤剂,特别是其中这些试剂调节存在于细胞中的酶和结构多肽的活性,例如 癌细胞或其中调节细胞系统(包括癌细胞)中基因表达水平的那些,以及含有这些试剂的药物组合物以及使用它们作为治疗剂的方法,以及制备这些试剂的方法 。
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公开(公告)号:US20080148346A1
公开(公告)日:2008-06-19
申请号:US11855914
申请日:2007-09-14
申请人: Ravinder Gill , Lee Cooper , Paul Young , Pankaj Srivastava , Boulos Aoun
发明人: Ravinder Gill , Lee Cooper , Paul Young , Pankaj Srivastava , Boulos Aoun
IPC分类号: H04L9/00
CPC分类号: H04L63/1408 , H04L63/20
摘要: A method comprises automatically obtaining network data, and automatically processing the network data to detect violation of a compliance control policy of an entity.
摘要翻译: 一种方法包括自动获得网络数据,并自动处理网络数据,以检测违反实体的合规性控制策略。
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公开(公告)号:US20080051338A1
公开(公告)日:2008-02-28
申请号:US11777133
申请日:2007-07-12
申请人: George Komatsoulis , Craig Rosen , Steven Ruben , Roxanne Duan , Paul Moore , Yanggu Shi , David LaFleur , Ying-Fei Wei , Jian Ni , Kimberly Florence , Paul Young , Laurie Brewer , Daniel Soppet , Gregory Endress , Reinhard Ebner , Henrik Olsen , Michael Mucenski
发明人: George Komatsoulis , Craig Rosen , Steven Ruben , Roxanne Duan , Paul Moore , Yanggu Shi , David LaFleur , Ying-Fei Wei , Jian Ni , Kimberly Florence , Paul Young , Laurie Brewer , Daniel Soppet , Gregory Endress , Reinhard Ebner , Henrik Olsen , Michael Mucenski
IPC分类号: A61K31/70 , A61K38/00 , C07K14/00 , C07K16/18 , C12N15/00 , C12N15/11 , C12N15/87 , C12N5/06 , C12P21/04 , C12Q1/68 , G01N33/53
摘要: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译: 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体,宿主细胞,抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病,病症和/或病症的诊断和治疗方法。
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公开(公告)号:US20070042416A1
公开(公告)日:2007-02-22
申请号:US11537686
申请日:2006-10-02
申请人: Paul Young , Steven Ruben
发明人: Paul Young , Steven Ruben
CPC分类号: C07K14/47 , A01K2217/05 , A01K2217/075 , A61K38/00 , A61K48/00 , A61K2039/5154 , C07K14/70596 , C07K2319/00 , C07K2319/30 , C12N2799/026
摘要: The present invention relates to a novel human protein called Dendritic Enriched Secreted Lymphocyte Activation Molecule, and isolated polynucleotides encoding this protein. Also provided are vectors, host cells, antibodies, and recombinant methods for producing this human protein. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to this novel human protein.
摘要翻译: 本发明涉及一种称为树突状分泌型分泌淋巴细胞活化分子的新型人类蛋白质,以及编码该蛋白质的分离的多核苷酸。 还提供了用于产生该人蛋白质的载体,宿主细胞,抗体和重组方法。 本发明还涉及用于诊断和治疗与该新型人蛋白相关的疾病的诊断和治疗方法。
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公开(公告)号:US20070020724A1
公开(公告)日:2007-01-25
申请号:US10886642
申请日:2004-07-09
申请人: Steven Ruben , Jian Ni , Craig Rosen , Ying-Fei Wei , Paul Young , Kimberly Florence , Daniel Soppet , Laurie Brewer , Gregory Endress , Kenneth Carter , Michael Mucenski , Reinhard Ebner , David LaFleur , Henrik Olsen , Yanggu Shi , Paul Moore , George Komatsoulis
发明人: Steven Ruben , Jian Ni , Craig Rosen , Ying-Fei Wei , Paul Young , Kimberly Florence , Daniel Soppet , Laurie Brewer , Gregory Endress , Kenneth Carter , Michael Mucenski , Reinhard Ebner , David LaFleur , Henrik Olsen , Yanggu Shi , Paul Moore , George Komatsoulis
CPC分类号: C07K14/47
摘要: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译: 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体,宿主细胞,抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病,病症和/或病症的诊断和治疗方法。
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公开(公告)号:US20070014787A1
公开(公告)日:2007-01-18
申请号:US11375555
申请日:2006-03-15
申请人: Steven Ruben , George Komatsoulis , D. Duan , Craig Rosen , Paul Moore , Yanggu Shi , David LaFleur , Reinhard Ebner , Henrik Olsen , Laurie Brewer , Kimberly Florence , Paul Young , Michael Mucenski , Gregory Endress , Daniel Soppet
发明人: Steven Ruben , George Komatsoulis , D. Duan , Craig Rosen , Paul Moore , Yanggu Shi , David LaFleur , Reinhard Ebner , Henrik Olsen , Laurie Brewer , Kimberly Florence , Paul Young , Michael Mucenski , Gregory Endress , Daniel Soppet
IPC分类号: A61K39/395 , C12Q1/68 , C07H21/04 , C12P21/06 , C07K14/705 , C07K16/28
CPC分类号: C07K14/47 , A61K38/00 , C07K2319/30
摘要: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译: 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体,宿主细胞,抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病,病症和/或病症的诊断和治疗方法。
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