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42 条记录 (耗时 0.027 秒)

    Medical adhesive sheet
    22.
    发明授权
    Medical adhesive sheet 失效
    医用胶片

    公开(公告)号：US6139867A

    公开(公告)日：2000-10-31

    申请号：US296427

    申请日：1994-08-26

    申请人： Takateru Muraoka ,  Takashi Kinoshita ,  Hitoshi Akemi ,  Saburo Otsuka

    发明人： Takateru Muraoka ,  Takashi Kinoshita ,  Hitoshi Akemi ,  Saburo Otsuka

    IPC分类号： A61F13/00 ,  A61F13/02 ,  A61K9/70 ,  A61L15/58 ,  A61L15/44

    CPC分类号： A61K9/7053 ,  A61F13/0233 ,  A61F13/0243 ,  A61F13/0253 ,  A61K9/7061 ,  A61L15/58 ,  A61F2013/00153 ,  A61F2013/00234 ,  A61F2013/00608 ,  A61F2013/00663 ,  A61F2013/0071 ,  A61F2013/00906

    摘要： A medical adhesive sheet comprising a support having a laminate structure comprising a non-porous sheet and a porous-sheet, and a pressure-sensitive layer comprising an acrylic polymer prepared by polymerizing an alkyl (meth)acrylate as a main component monomer, and an organic liquid component which is compatible with the acrylic polymer, formed on the porous sheet side of the support, the layer being subjected to a crosslinking treatment, wherein the pressure-sensitive adhesive layer is embedded in the porous sheet, reaching the laminate interface between the non-porous sheet and the porous sheet. The medical adhesive sheet has improved anchoring property of its pressure-sensitive adhesive layer to the support while exhibiting a good balance between adhesion to the skin and low irritation to the skin.

    摘要翻译： 一种医用胶粘片，其特征在于，具有包含无孔片材和多孔片材的叠层结构的支持体和包含通过聚合（甲基）丙烯酸烷基酯作为主要成分单体而制备的丙烯酸类聚合物的压敏层， 在支撑体的多孔片侧形成与丙烯酸类聚合物相容的有机液体成分，该层进行交联处理，其中粘合剂层嵌入多孔片中，到达层间界面 无孔片材和多孔片材。 医用粘合片具有改善其压敏粘合剂层对支持体的锚定性能，同时在与皮肤的粘附性和对皮肤的低刺激性之间具有良好的平衡。

    Adhesive material and adhesive preparation
    25.
    发明授权
    Adhesive material and adhesive preparation 有权
    胶粘材料和粘合剂制备

    公开(公告)号：US08394404B2

    公开(公告)日：2013-03-12

    申请号：US11196936

    申请日：2005-08-04

    申请人： Hitoshi Akemi ,  Kazuhisa Ninomiya ,  Hidetoshi Kuroda ,  Kensuke Matsuoka ,  Yuji Saeki ,  Masato Nishimura

    发明人： Hitoshi Akemi ,  Kazuhisa Ninomiya ,  Hidetoshi Kuroda ,  Kensuke Matsuoka ,  Yuji Saeki ,  Masato Nishimura

    IPC分类号： A61L15/16 ,  C08F136/00

    CPC分类号： A61K9/7053

    摘要： The present invention provides an adhesive material to be adhered to the skin etc., which maintains, for a certain time period after adhesion thereof to the skin surface, suitable adhesiveness that does not allow easy peeling or cause irritation to the skin, and which permits, when it is to be peeled off from the skin surface after the lapse of a desired certain time period, easy peeling without causing pain or physical irritation, and an adhesive preparation containing the adhesive material and a percutaneously absorbable drug in the adhesive layer. Specifically, the present invention provides an adhesive material containing a support and an adhesive layer laminated on one surface of the support, wherein the adhesive layer has an apparent viscosity at 30° C. of 0.2×104 to 10×104 Pa·s and comprises two kinds of synthetic rubbers having different flowability.

    摘要翻译： 本发明提供粘附到皮肤等上的粘合剂材料，其在粘附到皮肤表面上一段时间后保持适合的粘合性，其不容易剥离或对皮肤产生刺激，并且允许 当在期望的特定时间段之后要从皮肤表面剥离时，易于剥离而不引起疼痛或身体刺激，以及在粘合剂层中含有粘合剂材料和经皮吸收药物的粘合剂。 具体地说，本发明提供了一种粘合剂材料，其包含层叠在载体的一个表面上的载体和粘合剂层，其中所述粘合剂层在30℃下的表观粘度为0.2×10 4至1​​0×10 4 Pa·s，并且包含 两种具有不同流动性的合成橡胶。

    Medical adhesive composition, medical adhesive tape using the same and tape preparation for percutaneous absorption
    26.
    发明授权
    Medical adhesive composition, medical adhesive tape using the same and tape preparation for percutaneous absorption 失效

    公开(公告)号：US07056526B2

    公开(公告)日：2006-06-06

    申请号：US10230495

    申请日：2002-08-29

    申请人： Hidetoshi Kuroda ,  Takateru Muraoka ,  Keigo Inosaka ,  Hitoshi Akemi

    发明人： Hidetoshi Kuroda ,  Takateru Muraoka ,  Keigo Inosaka ,  Hitoshi Akemi

    IPC分类号： A61K9/70

    CPC分类号： A61K9/7061 ,  A61L15/58 ,  Y10T428/28 ,  C08L39/06

    摘要： The present invention provides a medical adhesive tape and a tape preparation for percutaneous absorption, both having an adhesive layer that resists glue remainder and stickiness upon peeling off of the tape even after adhesion to the human skin for a long time, and a medical adhesive composition to be used for such tapes. The medical adhesive composition of the present invention includes, as essential elements, (A) a copolymer containing (a) alkyl (meth)acrylate, wherein the alkyl moiety has 4 to 18 carbon atoms, in a proportion of not less than 50 wt % of the copolymer and (b) a carboxyl group-containing vinyl compound in a proportion of 0.1 wt %–10 wt % of the copolymer, (B) an alkoxide or a chelate compound of at least a metal selected from titanium, zirconium, zinc and aluminum, and (C) a polyol compound in a proportion of 0.2 wt %–5 wt % of the aforementioned medical adhesive composition. The medical adhesive tape of the present invention and tape preparation for percutaneous absorption are characterized in that the adhesive layer contains the above-mentioned medical adhesive composition of the present invention.

    Percutaneous absorption preparation
    27.
    发明授权
    Percutaneous absorption preparation 有权
    经皮吸收制剂

    公开(公告)号：US6132761A

    公开(公告)日：2000-10-17

    申请号：US146666

    申请日：1998-09-03

    申请人： Takateru Muraoka ,  Hitoshi Akemi ,  Keigo Inosaka ,  Hiroko Ishitani ,  Saburo Otsuka

    发明人： Takateru Muraoka ,  Hitoshi Akemi ,  Keigo Inosaka ,  Hiroko Ishitani ,  Saburo Otsuka

    IPC分类号： A61K9/70 ,  A61K47/14 ,  A61K47/22 ,  A61F13/02

    CPC分类号： A61K9/7053 ,  A61K47/14 ,  A61K47/22 ,  A61K9/0014 ,  A61K9/7061

    摘要： The present invention provides a percutaneous absorption preparation which hardly causes the coloration phenomenon and is excellent in the stability of the drug content. The percutaneous absorption preparation comprises a support and a pressure-sensitive adhesive layer formed on at least one side of the support, wherein the pressure-sensitive adhesive layer contains a percutaneous absorptive drug and at least one of 2-mercaptobenzimidazole and propyl gallate, with the proviso that the percutaneous absorptive drug is not 6-amino-5-chloro-1-isopropyl-2-(4-methyl-1-piperazinyl)benzimidazole and pharmacologically acceptable salt thereof.

    摘要翻译： 本发明提供一种几乎不引起着色现象并且药物含量稳定性优异的经皮吸收制剂。 经皮吸收制剂包括载体和形成在载体的至少一侧上的压敏粘合剂层，其中压敏粘合剂层含有经皮吸收药物和2-巯基苯并咪唑和没食子酸丙酯中的至少一种，其中 条件是经皮吸收药物不是6-氨基-5-氯-1-异丙基-2-（4-甲基-1-哌嗪基）苯并咪唑及其药理学上可接受的盐。

    Package structure of drug-containing pressure-sensitive adhesive sheet
    30.
    发明授权
    Package structure of drug-containing pressure-sensitive adhesive sheet 失效
    含药物压敏胶片的包装结构

    公开(公告)号：US5505306A

    公开(公告)日：1996-04-09

    申请号：US274162

    申请日：1994-07-14

    申请人： Hitoshi Akemi ,  Takashi Kinoshita ,  Takateru Muraoka ,  Kazuhiro Higashio ,  Saburo Otsuka

    发明人： Hitoshi Akemi ,  Takashi Kinoshita ,  Takateru Muraoka ,  Kazuhiro Higashio ,  Saburo Otsuka

    IPC分类号： A61B19/02 ,  A61F13/00 ,  A61F15/00 ,  A61K9/70 ,  A61B17/06

    CPC分类号： A61F15/001 ,  A61K9/703 ,  A61K9/7038 ,  A61B2050/002 ,  A61B2050/314 ,  A61F2013/00646 ,  A61F2013/00897

    摘要： A package structure, in which a drug-containing pressure-sensitive adhesive sheet comprising a support, a drug-containing pressure-sensitive adhesive layer, and a separator in this order is packaged and sealed in a packaging material, is disclosed, wherein unevenness is provided on at least one of the surface of the support on the side in contact with the inside of the packaging material, the surface of the separator on the side in contact with the inside of the packaging material, and the inside surface of the packaging material. The unevenness reduces the contact area between the packaging material and the sheet so that an adhesive, a plasticizer or any liquid component of the adhesive layer is prevented from adhering to the inside of the packaging material. Therefore, the sheet can easily be taken out of unit package on use.

    摘要翻译： 公开了一种封装结构，其中将包含载体，含药物的粘合剂层和隔膜的药物含压敏粘合片按包装材料包装和密封，其中不均匀性为 设置在与包装材料的内侧接触的一侧的支撑体的表面中的至少一个上，隔板的与包装材料的内部接触的一侧的表面和包装材料的内表面 。 不均匀性降低了包装材料和片材之间的接触面积，从而防止粘合剂，增塑剂或粘合剂层的任何液体成分粘附到包装材料的内部。 因此，在使用时，可以容易地将纸张从单元包装中取出。