STABLE PHARMACEUTICAL COMPOSITION OF FREEZE-DRIED TETRODOTOXIN POWDER
    22.
    发明申请
    STABLE PHARMACEUTICAL COMPOSITION OF FREEZE-DRIED TETRODOTOXIN POWDER 有权
    冷冻干燥四酮酮粉末的稳定的药物组合物

    公开(公告)号:US20120264767A1

    公开(公告)日:2012-10-18

    申请号:US13533907

    申请日:2012-06-26

    IPC分类号: A61K31/519

    摘要: This invention relates to a stable pharmaceutical composition of freeze-dried tetrodotoxin powder which contains trace amount of tetrodotoxin, substances which can stabilizes tetrodotoxin, including disaccharide(s) or polyglucose(s) or analogues thereof and solvent(s), and solvents which can help tetrodotoxin dissolve.

    摘要翻译: 本发明涉及含有微量河豚毒素的稳定的冻干河豚毒素粉末的稳定药物组合物,能够稳定河豚毒素的物质,包括其二糖或多葡萄糖或其类似物和溶剂, 帮助河豚毒素溶解。

    Multilayer container for enhanced gas barrier properties
    23.
    发明授权
    Multilayer container for enhanced gas barrier properties 有权
    用于提高阻气性能的多层容器

    公开(公告)号:US08124202B2

    公开(公告)日:2012-02-28

    申请号:US11850575

    申请日:2007-09-05

    IPC分类号: B32B1/02

    摘要: A multilayer container having enhanced gas barrier properties comprises at least two outer layers comprising a polymer matrix, and at least one barrier layer disposed between the at least two outer layers. The at least one barrier layer comprises a first polymer composition comprising a polymer matrix and a low molecular weight additive. In a particular embodiment, the low molecular weight additive comprises a purine derivative, such as caffeine, and is present in the multilayer container in an amount in the range of about 0.2 to about 10 weight percent of the container.

    摘要翻译: 具有增强的气体阻隔性能的多层容器包括至少两个包含聚合物基质的外层和设置在该至少两个外层之间的至少一个阻挡层。 所述至少一个阻挡层包括包含聚合物基质和低分子量添加剂的第一聚合物组合物。 在一个具体实施方案中,低分子量添加剂包括嘌呤衍生物,例如咖啡因,并且以多于容器的约0.2至约10重量%的量存在于多层容器中。

    Method to make single-layer pet bottles with high barrier and improved clarity
    25.
    发明授权
    Method to make single-layer pet bottles with high barrier and improved clarity 无效
    制造具有高屏障和改善清晰度的单层宠物瓶的方法

    公开(公告)号:US07943216B2

    公开(公告)日:2011-05-17

    申请号:US12768541

    申请日:2010-04-27

    摘要: The present invention comprises a blend of polyester and a partially aromatic polyamide with an ionic compatibilizer and a cobalt salt. This blend can be processed into a container that has both active and passive oxygen barrier and carbon dioxide barrier properties at an improved color and clarity than containers known in the art. The partially aromatic polyamide is preferably meta-xylylene adipamide. The ionic compatibilizer is preferably 5-sodiumsulfoisophthalic acid or 5-zincsulfoisophthalic acid, or their dialkyl esters such as the dimethyl ester (SIM) and glycol ester (SIPEG). The cobalt salt is selected form the class of cobalt acetate, cobalt carbonate, cobalt chloride, cobalt hydroxide, cobalt naphthenate, cobalt oleate, cobalt linoleate, cobalt octoate, cobalt stearate, cobalt nitrate, cobalt phosphate, cobalt sulfate, cobalt (ethylene glycolate), or mixtures of two or more of these. The partially aromatic polyamide is present in a range from about 1 to about 10 wt. % of said composition. The ionic compatibilizer is present in a range from about 0.1 to about 2.0 mol-% of said composition. The cobalt salt is present in a range from about 20 to about 500 ppm of said composition.

    摘要翻译: 本发明包括聚酯和部分芳族聚酰胺与离子增容剂和钴盐的共混物。 与现有技术中已知的容器相比,该混合物可以加工成具有主动和被动氧气阻隔性和二氧化碳阻隔性能的容器,其颜色和透明度得到改善。 部分芳族聚酰胺优选为间二甲苯基己二酰胺。 离子增容剂优选为5-钠磺基间苯二甲酸或5-锌磺基间苯二甲酸,或其二烷基酯如二甲酯(SIM)和乙二醇酯(SIPEG)。 钴盐选自乙酸钴,碳酸钴,氯化钴,氢氧化钴,环烷酸钴,油酸钴,亚油酸钴,辛酸钴,硬脂酸钴,硝酸钴,磷酸钴,硫酸钴,钴(乙醇酸)等。 ,或这些中的两种或更多种的混合物。 部分芳族聚酰胺的存在量为约1至约10重量%。 %的所述组合物。 离子相容剂的存在量为所述组合物的约0.1至约2.0mol%。 钴盐以所述组合物的约20至约500ppm的范围存在。

    METHOD TO MAKE SINGLE-LAYER PET BOTTLES WITH HIGH BARRIER AND IMPROVED CLARITY
    26.
    发明申请
    METHOD TO MAKE SINGLE-LAYER PET BOTTLES WITH HIGH BARRIER AND IMPROVED CLARITY 无效
    制备单层PET瓶的方法,具有高阻挡和改善的清晰度

    公开(公告)号:US20100209641A1

    公开(公告)日:2010-08-19

    申请号:US12768541

    申请日:2010-04-27

    IPC分类号: B32B1/02 C08L77/00

    摘要: The present invention comprises a blend of polyester and a partially aromatic polyamide with an ionic compatibilizer and a cobalt salt. This blend can be processed into a container that has both active and passive oxygen barrier and carbon dioxide barrier properties at an improved color and clarity than containers known in the art. The partially aromatic polyamide is preferably meta-xylylene adipamide. The ionic compatibilizer is preferably 5-sodiumsulfoisophthalic acid or 5-zinesulfoisophthalic acid, or their dialkyl esters such as the dimethyl ester (SIM) and glycol ester (SIPEG). The cobalt salt is selected form the class of cobalt acetate, cobalt carbonate, cobalt chloride, cobalt hydroxide, cobalt naphthenate, cobalt oleate, cobalt linoleate, cobalt octoate, cobalt stearate, cobalt nitrate, cobalt phosphate, cobalt sulfate, cobalt (ethylene glycolate), or mixtures of two or more of these. The partially aromatic polyamide is present in a range from about 1 to about 10 wt. % of said composition. The ionic compatibilizer is present in a range from about 0.1 to about 2.0 mol-% of said composition. The cobalt salt is present in a range from about 20 to about 500 ppm of said composition.

    摘要翻译: 本发明包括聚酯和部分芳族聚酰胺与离子增容剂和钴盐的共混物。 与现有技术中已知的容器相比,该混合物可以加工成具有主动和被动氧气阻隔性和二氧化碳阻隔性能的容器,其颜色和透明度得到改善。 部分芳族聚酰胺优选为间二甲苯基己二酰胺。 离子增容剂优选为5-钠磺基间苯二甲酸或5-锌磺基间苯二甲酸或其二烷基酯,如二甲酯(SIM)和乙二醇酯(SIPEG)。 钴盐选自乙酸钴,碳酸钴,氯化钴,氢氧化钴,环烷酸钴,油酸钴,亚油酸钴,辛酸钴,硬脂酸钴,硝酸钴,磷酸钴,硫酸钴,钴(乙醇酸)等。 ,或这些中的两种或更多种的混合物。 部分芳族聚酰胺的存在量为约1至约10重量%。 %的所述组合物。 离子相容剂的存在量为所述组合物的约0.1至约2.0mol%。 钴盐以所述组合物的约20至约500ppm的范围存在。

    BIO-BASED POLYETHYLENE TEREPHTHALATE POLYMER AND METHOD OF MAKING SAME
    27.
    发明申请
    BIO-BASED POLYETHYLENE TEREPHTHALATE POLYMER AND METHOD OF MAKING SAME 审中-公开
    生物基聚乙烯泰勒聚糖聚合物及其制备方法

    公开(公告)号:US20090246430A1

    公开(公告)日:2009-10-01

    申请号:US12210208

    申请日:2008-09-14

    摘要: A bio-based polyethylene terephthalate polymer comprising from about 25 to about 75 weight percent of a terephthalate component and from about 20 to about 50 weight percent of a diol component, wherein at least about one weight percent of at least one of the terephthalate and/or the diol component is derived from at least one bio-based material. A method of producing a bio-based polyethylene terephthalate polymer comprising obtaining a diol component comprising ethylene glycol, obtaining a terephthalate component comprising terephthalic acid, wherein at least one of the diol component and/or the diol component is derived from at least one bio-based material, and reacting the diol component and the terephthalate component to form a bio-based polyethylene terephthalate polymer comprising from about 25 to about 75 weight percent of the terephthalate component and from about 20 to about 50 weight percent of the diol component.

    摘要翻译: 一种基于生物的聚对苯二甲酸乙二醇酯聚合物,其包含约25至约75重量%的对苯二甲酸酯组分和约20至约50重量%的二醇组分,其中至少约1重量%的至少一种对苯二甲酸酯和/ 或二醇组分衍生自至少一种基于生物的材料。 一种制备生物基聚对苯二甲酸乙二醇酯聚合物的方法,包括获得包含乙二醇的二醇组分,得到包含对苯二甲酸的对苯二甲酸酯组分,其中至少一种二醇组分和/或二醇组分衍生自至少一种生物基聚对苯二甲酸乙二醇酯, 并使二元醇组分和对苯二甲酸酯组分反应形成一种生物基聚对苯二甲酸乙二醇酯聚合物,其包含约25至约75重量%的对苯二甲酸酯组分和约20至约50重量%的二醇组分。

    Method to reduce gel formation in pet resin
    30.
    发明授权
    Method to reduce gel formation in pet resin 失效
    减少宠物树脂凝胶形成的方法

    公开(公告)号:US5874515A

    公开(公告)日:1999-02-23

    申请号:US997144

    申请日:1997-12-23

    摘要: There is disclosed a process for reducing the number of gels generated in polyethylene terephthalate (PET) resin. Gels are crosslinked polymers created by thermal and thermo-oxidative degradation induced during polymer production. The instant process comprises the addition of primary and secondary antioxidants prior to the PET polycondensation reaction in order to reduce the amount of thermal degradation which occurs. The polyethylene terephthalate produced by this process formed approximately 25 to 90% fewer gels while maintaining physical properties suitable for use in fiber, film, and molding applications.

    摘要翻译: 公开了减少聚对苯二甲酸乙二醇酯(PET)树脂中产生的凝胶数量的方法。 凝胶是在聚合物生产过程中引起的热和热氧化降解产生的交联聚合物。 本方法包括在PET缩聚反应之前加入一级和二级抗氧化剂,以减少发生的热降解量。 通过该方法制备的聚对苯二甲酸乙二醇酯形成约25至90%的凝胶,同时保持适用于纤维,膜和模塑应用的物理性能。