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公开(公告)号：US20200338344A1
公开(公告)日：2020-10-29
申请号：US16855421
申请日：2020-04-22
Applicant: Boston Scientific Scimed, Inc.
Inventor： Brian L. Schmidt , Devon N. Arnholt , Benjamin Keith Stein , Keith R. Maile , William J. Linder , Ron A. Balczewski , Jacob M. Ludwig , Aleksandra Kharam
Abstract: Embodiments herein relate to medical devices and methods for using the same to treat cancerous tumors within a bodily tissue. A medical device system is included having at least one electric field generating circuit configured to generate one or more electric fields; control circuitry in communication with the electric field generating circuit, the control circuitry configured to control delivery of the one or more electric fields from the at least one electric field generating circuit; and two or more electrodes to deliver the electric fields to the site of a cancerous tumor within a patient. At least one electrode can be configured to be implanted. At least one electrode can be configured to be external. The control circuitry can cause the electric field generating circuit to generate one or more electric fields at frequencies selected from a range of between 10 kHz to 1 MHz.
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公开(公告)号：US20200330756A1
公开(公告)日：2020-10-22
申请号：US16850712
申请日：2020-04-16
Applicant: Boston Scientific Scimed, Inc.
Inventor： Brian L. Schmidt , Devon N. Arnholt , Benjamin Keith Stein , Keith R. Maile , William J. Linder , Ron A. Balczewski , Aleksandra Kharam
Abstract: Embodiments herein relate to a medical device for treating a cancerous tumor, the medical device having a first lead including a first wire and second wire; a second lead can include a third wire and fourth wire; and a first electrode in electrical communication with the first wire, a second electrode in electrical communication with the second wire, a third electrode in electrical communication with the third wire, and a fourth electrode in electrical communication with the fourth wire. The first and third electrodes form a supply electrode pair configured to deliver one or more electric fields to the cancerous tumor. The second and fourth electrodes form a sensing electrode pair configured to measure an impedance of the cancerous tumor independent of an impedance of the first electrode, the first wire, the third electrode, the third wire, and components in electrical communication therewith. Other embodiments are also included herein.
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公开(公告)号：US20250099752A1
公开(公告)日：2025-03-27
申请号：US18904484
申请日：2024-10-02
Applicant: Boston Scientific Scimed, Inc.
Inventor： Brian L. Schmidt , Benjamin Keith Stein , Keith R. Maile , Ron A. Balczewski , Aleksandra Kharam
Abstract: Embodiments herein relate to a method for treating a cancerous tumor located within a subject. The method can include applying one or more electric fields at or near a site of the cancerous tumor, where the cancerous tumor can include a cancerous cell population. The one or more applied electric fields are effective to delay mitosis and cause mitotic synchronization within a proportion of the cancerous cell population. The method can include removing the one or more electric fields to allow mitosis to proceed within the cancerous cell population. The method can include administering a chemotherapeutic agent to the subject after the one or more electric fields have been removed. Other embodiments are also included herein.
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公开(公告)号：US20240408387A1
公开(公告)日：2024-12-12
申请号：US18734618
申请日：2024-06-05
Applicant: Boston Scientific Scimed, Inc.
Inventor： Brian L. Schmidt
Abstract: Embodiments herein relate to methods, devices, and systems for the treatment of cancer tumor by combining TTF electrical field therapy with other types of cancer therapies. In an embodiment, a method for providing cancer therapy is included, the method applying one or more TTF electrical fields at or near a site of a cancerous tumor, a surgical excision site, and/or a targeted therapy site of a subject and administering a non-electrical field based cancer therapy to the subject, wherein applying the TTF electrical fields is performed before, after, and/or simultaneously with administering the non-electrical field based cancer therapy. Other embodiments are also included herein.
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Patent Agency Ranking
公开(公告)号：US20240325774A1
公开(公告)日：2024-10-03
申请号：US18619951
申请日：2024-03-28
Applicant: Boston Scientific Scimed, Inc.
Inventor： Andrew Brian Graveley , Daniel J. Foster , Kyle True , Brian L. Schmidt , Devon N. Arnholt
Abstract: Metabolic disorders such as Type 2 diabetes may be treated using a system that is adapted to modulate an hepatic neural plexus of a patient. The system includes a stimulation device adapted for implantation near the patient's hepatic neural plexus and to provide mechanical energy to the patient's hepatic neural plexus, a source of excitation energy adapted to provide excitation energy to the stimulation device, and a controller that is operably coupled to the source of excitation energy and is adapted to control the source of excitation energy.
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公开(公告)号：US20240115856A1
公开(公告)日：2024-04-11
申请号：US18215603
申请日：2023-06-28
Applicant: Boston Scientific Scimed, Inc.
Inventor： Brian L. Schmidt , Devon N. Arnholt , Benjamin Keith Stein , Keith R. Maile , William J. Linder , Ron A. Balczewski , Aleksandra Kharam
IPC: A61N1/36 , A61B5/0538 , A61N1/05
CPC classification number: A61N1/36002 , A61B5/0538 , A61N1/05
Abstract: Embodiments herein relate to a medical device for treating a cancerous tumor, the medical device having a first lead including a first wire and second wire; a second lead can include a third wire and fourth wire; and a first electrode in electrical communication with the first wire, a second electrode in electrical communication with the second wire, a third electrode in electrical communication with the third wire, and a fourth electrode in electrical communication with the fourth wire. The first and third electrodes form a supply electrode pair configured to deliver one or more electric fields to the cancerous tumor. The second and fourth electrodes form a sensing electrode pair configured to measure an impedance of the cancerous tumor independent of an impedance of the first electrode, the first wire, the third electrode, the third wire, and components in electrical communication therewith. Other embodiments are also included herein.
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公开(公告)号：US20200330757A1
公开(公告)日：2020-10-22
申请号：US16850720
申请日：2020-04-16
Applicant: Boston Scientific Scimed, Inc.
Inventor： Brian L. Schmidt , Benjamin Keith Stein , Keith R. Maile , William J. Linder , Ron A. Balczewski , Sarah Melissa Gruba , Tucker James Nelson , Aleksandra Kharam
Abstract: Embodiments herein relate to a medical device for treating a cancerous tumor, including an electric field generating circuit configured to generate one or more electric fields at or near a site of the cancerous tumor and control circuitry in communication with the electric field generating circuit. The medical device includes one or more supply wires in electrical communication with the electric field generating circuit and one or more supply electrodes. The supply electrodes are configured to deliver an electric field at or near the site of the cancerous tumor. The medical device can include one or more sensing wires in electrical communication with the control circuitry and one or more sensing electrodes. The sensing electrodes can be configured to measure an impedance of the cancerous tumor at at least two different electric field strengths. Other embodiments are also included herein.
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公开(公告)号：US10251768B2
公开(公告)日：2019-04-09
申请号：US14523095
申请日：2014-10-24
Applicant: Boston Scientific Scimed, Inc.
Inventor： Brian L. Schmidt , James P. Rohl , Devon N. Arnholt , Joel T. Eggert , Mary M. Byron , Douglas D. Pagoria , Todd College
IPC: A61F5/00
Abstract: According to aspects of the present disclosure, a retrieval catheter assembly for retrieving an intragastric balloon may include a tubular member configured to pass through a wall of the intragastric balloon. The retrieval catheter assembly may also include a retrieval member coupled to the tubular member and movable between an undeployed configuration and a deployed configuration. In the undeployed configuration the retrieval member may be substantially aligned with the tubular member. In the deployed configuration at least a portion of the retrieval member may diverge from the tubular member and may be configured to engage the wall of the intragastric balloon.
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公开(公告)号：US09713703B2
公开(公告)日：2017-07-25
申请号：US14455560
申请日：2014-08-08
Applicant: Boston Scientific Scimed, Inc.
Inventor： Bryan Allen Clark , Brian L. Schmidt , Aiden Flanagan
CPC classification number: A61M37/00 , A61B17/12104 , A61B17/12186 , A61B17/1219 , A61B2017/00893 , A61B2017/00898 , A61B2017/1205
Abstract: Exemplary embodiments of devices and methods for treating a lung including, for example, treatments for chronic obstructive pulmonary disease are disclosed. A device may include a plurality of media and a deployment member. The media may be configured for deployment into one or more airways of a lung. The deployment member may be configured for insertion into or proximate the one or more airways of the lung. Also, the deployment member may be configured to deploy the plurality of media substantially simultaneously. Further, the plurality of media may be configured to be retained within the one or more airways of the lung.
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