公开(公告)号：US20210217520A1

公开(公告)日：2021-07-15

申请号：US17125713

申请日：2020-12-17

Applicant: Cercacor Laboratories, Inc.

Inventor： Marcelo M. Lamego ,  Jeroen Poeze

IPC: G16H40/67 ,  G06Q20/14 ,  A61B5/00 ,  H04L12/26

Abstract: A physiological test credit method determines if test credits are available to the monitor and checks if a Wi-Fi connection is available. If test credits are less than a test credit threshold, the monitor connects to a test credit server, processes server commands so as to download test credits and disconnects from the server. In various embodiments, the monitor is challenged to break a server code, the server is challenged to break a monitor code. The server validates monitor serial codes, and saves monitor configuration parameters.

公开(公告)号：US11026604B2

公开(公告)日：2021-06-08

申请号：US16034743

申请日：2018-07-13

Applicant: Cercacor Laboratories, Inc.

Inventor： Jesse Chen ,  Sean Merritt ,  Cristiano Dalvi ,  Ferdyan Lesmana ,  Hung The Vo ,  Kevin Hughes Pauley ,  Jeroen Poeze ,  Ruiqi Long ,  Stephen L. Monfre

IPC: A61B5/02 ,  A61B5/145 ,  A61B5/00 ,  A61B5/0205 ,  A61B5/026 ,  A61B5/0295 ,  A61B5/0531 ,  A61B5/107 ,  A61B5/1455

Abstract: Systems, methods, apparatuses, and medical devices for harmonizing data from a plurality of non-invasive sensors are described. A physiological parameter can be determined by harmonizing data between two or more different types of non-invasive physiological sensors interrogating the same or proximate measurement sites. Data from one or more first non-invasive sensors can be utilized to identify one or more variables that are useful in one or more calculations associated with data from one or more second non-invasive sensors. Data from one or more first non-invasive sensors can be utilized to calibrate one or more second non-invasive sensors. Non-invasive sensors can include, but are not limited to, an optical coherence tomography (OCT) sensor, a bio-impedance sensor, a tissue dielectric constant sensor, a plethysmograph sensor, or a Raman spectrometer.

公开(公告)号：US09989560B2

公开(公告)日：2018-06-05

申请号：US14297470

申请日：2014-06-05

Applicant: CERCACOR LABORATORIES, INC.

Inventor： Jeroen Poeze ,  Jesse Chen ,  Mathew Paul ,  Marcelo Lamego ,  Massi Joe E. Kiani

IPC: G01R13/02 ,  G01R29/08 ,  A61B5/1455 ,  A61B5/00 ,  A61B5/026 ,  A61B5/145

CPC classification number: G01R13/0281 ,  A61B5/0015 ,  A61B5/0261 ,  A61B5/14532 ,  A61B5/14551 ,  A61B5/7203 ,  A61B5/7228 ,  A61B2560/0242 ,  A61B2560/0276 ,  G01R29/0814

Abstract: A system is disclosed for detecting and calculating the level of ambient and/or environmental noise, such as electromagnetic interference generated by electric power lines, ambient lights, light dimmers, television or computer displays, power supplies or transformers, and medical equipment. In some embodiments, the system performs frequency analysis on the interference signal detected by light photodetectors and determines the power of the interference signal concentrated in the analyzed frequency bands. The worst-case interference level can be determined by selecting the maximum from the computed power values. In some embodiments, the determined interference signal power can be compared with the noise tolerance of a patient monitoring system configured to reliably and noninvasively detect physiological parameters of a user. The results of the comparison can be presented to the user audio-visually. In some embodiments, the system can be used to perform spot check measurements of electromagnetic interference.

公开(公告)号：US20160367173A1

公开(公告)日：2016-12-22

申请号：US15160907

申请日：2016-05-20

Applicant: Cercacor Laboratories, Inc.

Inventor： Cristiano Dalvi ,  Ferdyan Lesmana ,  Hung Vo ,  Jeroen Poeze ,  Jesse Chen ,  Kevin Pauley ,  Mathew Paul ,  Sean Merritt ,  Thomas B. Blank ,  Massi Joe E. Kiani

IPC: A61B5/145 ,  A61B5/1455 ,  A61B5/00

CPC classification number: A61B5/14552 ,  A61B5/0075 ,  A61B5/6838 ,  A61B2562/0238

Abstract: An optical physiological sensor configured to perform high speed spectral sweep analysis of sample tissue being measured to non-invasively predict an analyte level of a patient. An emitter of the optical physiological sensor can be regulated to operate at different temperatures to emit radiation at different wavelengths. Variation in emitter drive current, duty cycle, and forward voltage can also be used to cause the emitter to emit a range of wavelengths. Informative spectral data can be obtained during the sweeping of specific wavelength regions of sample tissue.

Abstract translation: 一种光学生理传感器，其被配置为对被测量的样品组织进行高速光谱扫描分析，以非侵入性地预测患者的分析物水平。 可以调节光学生理传感器的发射器以在不同温度下操作以发射不同波长的辐射。 发射极驱动电流，占空比和正向电压的变化也可用于使发射极发射波长范围。 在扫描样品组织的特定波长区域期间可以获得信息谱数据。

公开(公告)号：US08909310B2

公开(公告)日：2014-12-09

申请号：US14153895

申请日：2014-01-13

Applicant: Cercacor Laboratories, Inc.

Inventor： Marcelo M. Lamego ,  Sean Merritt ,  Cristiano Dalvi ,  Hung Vo ,  Johannes Bruinsma ,  Jeroen Poeze ,  Ferdyan Lesmana ,  Massi Joe E. Kiani

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1455

CPC classification number: A61B5/1455 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14552 ,  A61B5/6816 ,  A61B5/6826 ,  A61B5/6829 ,  A61B5/6838 ,  A61B5/6843 ,  A61B2562/0233 ,  A61B2562/04 ,  A61B2562/046 ,  A61B2562/146

Abstract: The present disclosure relates to an interface for a noninvasive glucose sensor that comprises a front-end adapted to receive an input signals from optical detectors and provide corresponding digital signals. In one embodiment, the front-end comprises switched capacitor circuits that are capable of handling multiple streams signals from the optical detectors. In another embodiment, the front-end comprises transimpedance amplifiers that are capable of handling multiple streams of input signals. In this embodiment, the transimpedance amplifier may be configured based on its own characteristics, such as its impedance, the impedance of the photodiodes to which it is coupled, and the number of photodiodes to which it is coupled.

公开(公告)号：US20140275808A1

公开(公告)日：2014-09-18

申请号：US14209844

申请日：2014-03-13

Applicant: Cercacor Laboratories, Inc.

Inventor： Jeroen Poeze ,  Marcelo M. Lamego

IPC: A61B5/00

CPC classification number: A61B5/684 ,  A61B5/14551 ,  A61B5/6826 ,  A61B5/7405 ,  A61B5/742 ,  A61B5/743

Abstract: A monitoring device for measuring one or more physiological parameters of a medical patient can include a finger clip sensor connected to a monitor. A placement indicator helps the patient to properly position the sensor. The monitor can display a message alerting the patient to reposition the sensor. The device can delay measurement until the sensor is properly positioned.

Abstract translation: 用于测量医疗患者的一个或多个生理参数的监测装置可以包括连接到监视器的手指夹传感器。 放置指示器可帮助患者正确定位传感器。 显示器可以显示警告患者重新定位传感器的消息。 该设备可以延迟测量直到传感器正确定位。

公开(公告)号：US20140129702A1

公开(公告)日：2014-05-08

申请号：US14071447

申请日：2013-11-04

Applicant: Cercacor Laboratories, Inc.

Inventor： Marcelo M. Lamego ,  Jeroen Poeze

IPC: H04L12/26

CPC classification number: H04L43/16 ,  A61B5/0002 ,  A61B5/14551 ,  A61B2560/028 ,  G06F19/00 ,  G06F19/3418 ,  G06Q20/145 ,  G06Q50/22

Abstract: A physiological test credit method determines if test credits are available to the monitor and checks if a Wi-Fi connection is available. If test credits are less than a test credit threshold, the monitor connects to a test credit server, processes server commands so as to download test credits and disconnects from the server. In various embodiments, the monitor is challenged to break a server code, the server is challenged to break a monitor code. The server validates monitor serial codes, and saves monitor configuration parameters.

Abstract translation: 生理测试信用方法确定测试信用是否可用于监视器，并检查Wi-Fi连接是否可用。 如果测试信用度低于测试信用阈值，则监视器连接到测试信用服务器，处理服务器命令，以便下载测试信用和从服务器断开连接。 在各种实施例中，监视器面临破坏服务器代码的挑战，服务器面临破坏监视器代码的挑战。 服务器验证监控序列号，并保存监控配置参数。

公开(公告)号：US20140121482A1

公开(公告)日：2014-05-01

申请号：US14064055

申请日：2013-10-25

Applicant: CERCACOR LABORATORIES, INC.

Inventor： Sean Merritt ,  Marcelo Lamego ,  Cristiano Dalvi ,  Hung Vo ,  Johannes Bruinsma ,  Jeroen Poeze ,  Ferdyan Lesmana ,  Massi Joe E. Kiani

IPC: A61B5/1455

CPC classification number: A61B5/1455 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14552 ,  A61B5/6816 ,  A61B5/6826 ,  A61B5/6829 ,  A61B5/6838 ,  A61B5/6843 ,  A61B2562/0233 ,  A61B2562/04 ,  A61B2562/046 ,  A61B2562/146

Abstract: The present disclosure relates to a sensor having a set of photodetectors that are arranged at various locations to enable the measurement of blood glucose. The photodetectors are arranged across multiple locations. For example, the detector may comprise multiple photodetector arrays that are arranged to have a sufficient difference in mean path length to allow for noise cancellation and noise reduction. Walls may be used in the detector to separate individual photodetectors and prevent mixing of detected optical radiation between the different locations on the measurement site. A window may also be employed to facilitate the passing of optical radiation at various wavelengths for measuring glucose in the tissue.

Abstract translation: 本公开涉及具有一组光电检测器的传感器，其被布置在各种位置以能够测量血糖。 光电探测器布置在多个位置。 例如，检测器可以包括多个光电检测器阵列，其布置成在平均路径长度上具有足够的差异以允许噪声消除和降噪。 可以在检测器中使用壁来分离各个光电检测器，并防止检测的光辐射在测量位置上的不同位置之间的混合。 还可以使用窗口来促进用于测量组织中葡萄糖的各种波长的光辐射的通过。

公开(公告)号：US20130317370A1

公开(公告)日：2013-11-28

申请号：US13888266

申请日：2013-05-06

Applicant: Cercacor Laboratories, Inc.

Inventor： Cristiano Dalvi ,  Marcelo Lamego ,  Sean Merritt ,  Hung Vo ,  Johannes Bruinsma ,  Jeroen Poeze ,  Ferydan Lesmana ,  Greg Olsen ,  Massi Joe E. Kiani

IPC: A61B5/024 ,  A61B5/145 ,  A61B5/00 ,  A61B5/1455

CPC classification number: A61B5/02427 ,  A61B5/02416 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/4875 ,  A61B5/6816 ,  A61B5/6826 ,  A61B5/6829 ,  A61B5/6838 ,  A61B5/6843 ,  A61B5/70 ,  A61B5/7275 ,  A61B2562/146

Abstract: A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a bump interposed between a light source and a photodetector. The bump can be placed in contact with body tissue of a patient and thereby reduce a thickness of the body tissue. As a result, an optical pathlength between the light source and the photodetector can be reduced. In addition, the sensor can include a heat sink that can direct heat away from the light source. Moreover, the sensor can include shielding in the optical path between the light source and the photodetector. The shielding can reduce noise received by the photodetector.

Abstract translation: 用于测量医疗患者的一个或多个生理参数的无创生理传感器可以包括插入在光源和光电检测器之间的凸块。 凸起可以放置成与患者的身体组织接触，从而减少身体组织的厚度。 结果，可以减少光源和光电检测器之间的光程。 此外，传感器可以包括可将热量远离光源引导的散热器。 此外，传感器可以包括在光源和光电检测器之间的光路中的屏蔽。 屏蔽可以降低由光电检测器接收的噪声。

公开(公告)号：US20240164723A1

公开(公告)日：2024-05-23

申请号：US18521712

申请日：2023-11-28

Applicant: Cercacor Laboratories, Inc.

Inventor： Cristiano Dalvi ,  Jeroen Poeze

IPC: A61B5/00 ,  A61B5/026 ,  A61B5/1455 ,  A61B5/1491

CPC classification number: A61B5/7203 ,  A61B5/0261 ,  A61B5/14552 ,  A61B5/1491 ,  A61B5/7278 ,  A61B2560/0214 ,  A61B2562/185 ,  A61B2562/222 ,  A61B2562/227

Abstract: A sensor system has a low-noise sensor controller providing communications between an active-temperature-regulated optical sensor and an external monitor. A low-noise sensor controller drives optical emitters, receives resulting detected signals after attenuation by a blood perfused tissue site and communicates the detector signals to the attached signal processor. An optically-isolated controller front-end receives and digitizes the detected signals. A controller serializer transmits the digitized detector signal to the processor via a single, shielded coaxial cable.