公开(公告)号：US11684296B2

公开(公告)日：2023-06-27

申请号：US16721527

申请日：2019-12-19

Applicant: Cercacor Laboratories, Inc.

Inventor： Hung The Vo ,  Kevin Hughes Pauley ,  Cristiano Dalvi ,  Sean Merritt ,  Jesse Chen ,  Jeroen Poeze ,  Ferdyan Lesmana ,  Ruiqi Long

IPC: A61B5/1455 ,  A61B5/00

CPC classification number: A61B5/1455 ,  A61B5/6826 ,  A61B5/6838 ,  A61B2562/0242

Abstract: A noninvasive physiological sensor can include a first body portion and a second body portion coupled to each other and configured to at least partially enclose a user's finger. The sensor can further include a first probe coupled to one or more emitters and a second probe coupled to a detector. The first probe can direct light emitted from the one or more emitters toward tissue of the user's finger and the second probe can direct light attenuated through the tissue to the detector. The first and second probes can be coupled to the first and second body portions such that when the first and second body portions are rotated with respect to one another, ends of the first and second probes can be moved in a direction towards one another to compress the tissue of the user's finger.

公开(公告)号：US11653862B2

公开(公告)日：2023-05-23

申请号：US15160907

申请日：2016-05-20

Applicant: Cercacor Laboratories, Inc.

Inventor： Cristiano Dalvi ,  Ferdyan Lesmana ,  Hung The Vo ,  Jeroen Poeze ,  Jesse Chen ,  Kevin Hughes Pauley ,  Mathew Paul ,  Sean Merritt ,  Thomas B. Blank ,  Massi Joe E. Kiani

IPC: A61B5/1455 ,  A61B5/00

CPC classification number: A61B5/14552 ,  A61B5/0075 ,  A61B5/6838 ,  A61B2562/0238

Abstract: An optical physiological sensor configured to perform high speed spectral sweep analysis of sample tissue being measured to non-invasively predict an analyte level of a patient. An emitter of the optical physiological sensor can be regulated to operate at different temperatures to emit radiation at different wavelengths. Variation in emitter drive current, duty cycle, and forward voltage can also be used to cause the emitter to emit a range of wavelengths. Informative spectral data can be obtained during the sweeping of specific wavelength regions of sample tissue.

公开(公告)号：US20200163597A1

公开(公告)日：2020-05-28

申请号：US16697814

申请日：2019-11-27

Applicant: Cercacor Laboratories, Inc.

Inventor： Cristiano Dalvi ,  Hung The Vo ,  Jeroen Poeze ,  Ferdyan Lesmana ,  Jesse Chen ,  Kevin Hughes Pauley ,  Ruiqi Long ,  Stephen Leonard Monfre ,  Sean Merritt ,  Mohamed K. Diab ,  Massi Joe E. Kiani

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/053 ,  A61B5/01

Abstract: Systems, methods, and apparatuses for enabling a plurality of non-invasive, physiological sensors to obtain physiological measurements from the same tissue site. Each of a plurality of sensors can be integrated with or attached to a multi-sensor apparatus. The multi-sensor apparatus can orient the plurality of non-invasive, physiological sensors such that each of the plurality of non-invasive, physiological sensors obtains physiological data from the same or a similar location.

公开(公告)号：US20240180451A1

公开(公告)日：2024-06-06

申请号：US18494585

申请日：2023-10-25

Applicant: Cercacor Laboratories, Inc.

Inventor： Mohamed K. Diab ,  Kevin Hughes Pauley ,  Jesse Chen ,  Cristiano Dalvi ,  Hung The Vo ,  Ferdyan Lesmana ,  Jeroen Poeze ,  Ruiqi Long ,  Venkatramanan Krishnamani ,  Frank Lee

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1455 ,  G02B27/30

CPC classification number: A61B5/14532 ,  A61B5/1455 ,  A61B5/6826 ,  G02B27/30

Abstract: Systems, methods, and apparatuses for enabling a plurality of non-invasive, physiological sensors to obtain physiological measurements from essentially the same, overlapping, or proximate regions of tissue of a patient are disclosed. Each of a plurality of sensors can be integrated with or attached to a multi-sensor apparatus and can be oriented such that each sensor is directed towards, or can obtain a measurement from, the same or a similar location.

公开(公告)号：US09445759B1

公开(公告)日：2016-09-20

申请号：US13726539

申请日：2012-12-24

Applicant: Cercacor Laboratories, Inc.

Inventor： Marcelo M. Lamego ,  Massi Joe E. Kiani ,  Jesse Chen ,  Mathew Paul ,  Hoi Wong

IPC: A61B5/1455 ,  A61B5/1495 ,  A61B5/0205 ,  A61B5/026 ,  A61B5/145 ,  A61B5/15

CPC classification number: A61B5/1495 ,  A61B5/0205 ,  A61B5/0261 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/150358 ,  A61B2560/0223 ,  A61B2562/0295

Abstract: A blood glucose calibration system has a noninvasive sensor that attaches to a person's tissue site so as to generate multi-stream physiological data responsive to that person's blood constituents. Composite parameters, each in the form of a mathematical combination of invasive blood panel parameters, are derived from a general population and are responsive to the multi-stream physiological data. A population-based, blood glucose estimate for that person is derived from a weighted and scaled combination of these composite parameters. An individualized blood glucose estimate is then derived from the population-based blood glucose estimate and intermittent invasive test strip measurements of that particular individual.

Abstract translation: 血糖校准系统具有附着于人的组织部位的无创传感器，以产生响应于该人血液成分的多流生理数据。 复合参数，各自以侵入性血液面板参数的数学组合的形式，从一般群体导出，并响应于多流生理数据。 该人的基于人群的血糖估计来自这些复合参数的加权和缩放组合。 然后从基于群体的血糖估计和该特定个体的间歇性侵入性测试条测量得到个体化的血糖估计值。

公开(公告)号：US11992311B2

公开(公告)日：2024-05-28

申请号：US17324396

申请日：2021-05-19

Applicant: Cercacor Laboratories, Inc.

Inventor： Jesse Chen ,  Sean Merritt ,  Cristiano Dalvi ,  Ferdyan Lesmana ,  Hung The Vo ,  Kevin Hughes Pauley ,  Jeroen Poeze ,  Ruiqi Long ,  Stephen L Monfre

IPC: A61B5/00 ,  A61B5/0205 ,  A61B5/145 ,  A61B5/026 ,  A61B5/0295 ,  A61B5/0531 ,  A61B5/107 ,  A61B5/1455

CPC classification number: A61B5/14532 ,  A61B5/0075 ,  A61B5/0205 ,  A61B5/7203 ,  A61B5/7278 ,  A61B5/0066 ,  A61B5/0261 ,  A61B5/0295 ,  A61B5/0531 ,  A61B5/1075 ,  A61B5/1079 ,  A61B5/14551 ,  A61B5/442 ,  A61B5/443 ,  A61B2560/0223 ,  A61B2576/02

Abstract: Systems, methods, apparatuses, and medical devices for harmonizing data from a plurality of non-invasive sensors are described. A physiological parameter can be determined by harmonizing data between two or more different types of non-invasive physiological sensors interrogating the same or proximate measurement sites. Data from one or more first non-invasive sensors can be utilized to identify one or more variables that are useful in one or more calculations associated with data from one or more second non-invasive sensors. Data from one or more first non-invasive sensors can be utilized to calibrate one or more second non-invasive sensors. Non-invasive sensors can include, but are not limited to, an optical coherence tomography (OCT) sensor, a bio-impedance sensor, a tissue dielectric constant sensor, a plethysmograph sensor, or a Raman spectrometer.

公开(公告)号：US20210378562A1

公开(公告)日：2021-12-09

申请号：US17324396

申请日：2021-05-19

Applicant: Cercacor Laboratories, Inc.

Inventor： Jesse Chen ,  Sean Merritt ,  Cristiano Dalvi ,  Ferdyan Lesmana ,  Hung The Vo ,  Kevin Hughes Pauley ,  Jeroen Poeze ,  Ruiqi Long ,  Stephen L. Monfre

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/0205

Abstract: Systems, methods, apparatuses, and medical devices for harmonizing data from a plurality of non-invasive sensors are described. A physiological parameter can be determined by harmonizing data between two or more different types of non-invasive physiological sensors interrogating the same or proximate measurement sites. Data from one or more first non-invasive sensors can be utilized to identify one or more variables that are useful in one or more calculations associated with data from one or more second non-invasive sensors. Data from one or more first non-invasive sensors can be utilized to calibrate one or more second non-invasive sensors. Non-invasive sensors can include, but are not limited to, an optical coherence tomography (OCT) sensor, a bio-impedance sensor, a tissue dielectric constant sensor, a plethysmograph sensor, or a Raman spectrometer.

公开(公告)号：US11026604B2

公开(公告)日：2021-06-08

申请号：US16034743

申请日：2018-07-13

Applicant: Cercacor Laboratories, Inc.

Inventor： Jesse Chen ,  Sean Merritt ,  Cristiano Dalvi ,  Ferdyan Lesmana ,  Hung The Vo ,  Kevin Hughes Pauley ,  Jeroen Poeze ,  Ruiqi Long ,  Stephen L. Monfre

IPC: A61B5/02 ,  A61B5/145 ,  A61B5/00 ,  A61B5/0205 ,  A61B5/026 ,  A61B5/0295 ,  A61B5/0531 ,  A61B5/107 ,  A61B5/1455

Abstract: Systems, methods, apparatuses, and medical devices for harmonizing data from a plurality of non-invasive sensors are described. A physiological parameter can be determined by harmonizing data between two or more different types of non-invasive physiological sensors interrogating the same or proximate measurement sites. Data from one or more first non-invasive sensors can be utilized to identify one or more variables that are useful in one or more calculations associated with data from one or more second non-invasive sensors. Data from one or more first non-invasive sensors can be utilized to calibrate one or more second non-invasive sensors. Non-invasive sensors can include, but are not limited to, an optical coherence tomography (OCT) sensor, a bio-impedance sensor, a tissue dielectric constant sensor, a plethysmograph sensor, or a Raman spectrometer.

公开(公告)号：US09989560B2

公开(公告)日：2018-06-05

申请号：US14297470

申请日：2014-06-05

Applicant: CERCACOR LABORATORIES, INC.

Inventor： Jeroen Poeze ,  Jesse Chen ,  Mathew Paul ,  Marcelo Lamego ,  Massi Joe E. Kiani

IPC: G01R13/02 ,  G01R29/08 ,  A61B5/1455 ,  A61B5/00 ,  A61B5/026 ,  A61B5/145

CPC classification number: G01R13/0281 ,  A61B5/0015 ,  A61B5/0261 ,  A61B5/14532 ,  A61B5/14551 ,  A61B5/7203 ,  A61B5/7228 ,  A61B2560/0242 ,  A61B2560/0276 ,  G01R29/0814

Abstract: A system is disclosed for detecting and calculating the level of ambient and/or environmental noise, such as electromagnetic interference generated by electric power lines, ambient lights, light dimmers, television or computer displays, power supplies or transformers, and medical equipment. In some embodiments, the system performs frequency analysis on the interference signal detected by light photodetectors and determines the power of the interference signal concentrated in the analyzed frequency bands. The worst-case interference level can be determined by selecting the maximum from the computed power values. In some embodiments, the determined interference signal power can be compared with the noise tolerance of a patient monitoring system configured to reliably and noninvasively detect physiological parameters of a user. The results of the comparison can be presented to the user audio-visually. In some embodiments, the system can be used to perform spot check measurements of electromagnetic interference.

公开(公告)号：US20160367173A1

公开(公告)日：2016-12-22

申请号：US15160907

申请日：2016-05-20

Applicant: Cercacor Laboratories, Inc.

Inventor： Cristiano Dalvi ,  Ferdyan Lesmana ,  Hung Vo ,  Jeroen Poeze ,  Jesse Chen ,  Kevin Pauley ,  Mathew Paul ,  Sean Merritt ,  Thomas B. Blank ,  Massi Joe E. Kiani

IPC: A61B5/145 ,  A61B5/1455 ,  A61B5/00

CPC classification number: A61B5/14552 ,  A61B5/0075 ,  A61B5/6838 ,  A61B2562/0238

Abstract: An optical physiological sensor configured to perform high speed spectral sweep analysis of sample tissue being measured to non-invasively predict an analyte level of a patient. An emitter of the optical physiological sensor can be regulated to operate at different temperatures to emit radiation at different wavelengths. Variation in emitter drive current, duty cycle, and forward voltage can also be used to cause the emitter to emit a range of wavelengths. Informative spectral data can be obtained during the sweeping of specific wavelength regions of sample tissue.

Abstract translation: 一种光学生理传感器，其被配置为对被测量的样品组织进行高速光谱扫描分析，以非侵入性地预测患者的分析物水平。 可以调节光学生理传感器的发射器以在不同温度下操作以发射不同波长的辐射。 发射极驱动电流，占空比和正向电压的变化也可用于使发射极发射波长范围。 在扫描样品组织的特定波长区域期间可以获得信息谱数据。