公开(公告)号：US20160266066A1

公开(公告)日：2016-09-15

申请号：US15036261

申请日：2013-11-12

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Long Pan ,  Shaotang Yuan ,  Iraklis Pappas ,  John Vaughn ,  James G. Masters

IPC: G01N27/447 ,  A61K8/28 ,  A61Q15/00 ,  A61K8/19 ,  A61K8/44 ,  A61K8/26 ,  A61K8/27

CPC classification number: G01N27/44782 ,  A61K8/19 ,  A61K8/26 ,  A61K8/27 ,  A61K8/28 ,  A61K8/44 ,  A61K2800/58 ,  A61K2800/74 ,  A61K2800/805 ,  A61Q15/00 ,  D06M13/005

Abstract: Methods of estimating the suitability of a candidate antiperspirant material by measuring the zeta potential of the material.

Abstract translation: 通过测量材料的ζ电位来估计候选止汗材料的适用性的方法。

公开(公告)号：US12165749B2

公开(公告)日：2024-12-10

申请号：US18450011

申请日：2023-08-15

Applicant: Colgate-Palmolive Company

Inventor： Iraklis Pappas ,  Bartosz Luczynski ,  Donghui Wu ,  Dong Hyun Kim

IPC: G16C20/30 ,  G16C20/10 ,  G16C20/70

Abstract: In one embodiment, a method includes receiving identities of features of a first composition, and receiving a value of a property of the first composition. A learning model is trained using values of predefined characteristics of the features of the first composition, and the value of the property of the first composition. The learning model is then provided identities of second features of a second composition. Using the learning model, a value of a property of the second composition is determined and displayed.

公开(公告)号：US11904040B2

公开(公告)日：2024-02-20

申请号：US17853862

申请日：2022-06-29

Applicant: Colgate-Palmolive Company

Inventor： Tatiana Brinzari ,  Michael Stranick ,  Chi-Yuan Cheng ,  Zhigang Hao ,  Iraklis Pappas ,  Greggory Marron ,  Viktor Dubovoy ,  Long Pan

IPC: A61K8/44 ,  A61K8/02 ,  A61K8/27 ,  A61K8/46 ,  A61Q11/00

CPC classification number: A61K8/44 ,  A61K8/022 ,  A61K8/27 ,  A61K8/463 ,  A61Q11/00 ,  A61K2800/58 ,  A61K2800/92

Abstract: Described herein are zinc-amino acid-lauryl sulfate complexes and oral care compositions comprising the same; and methods of making and using the same are also described.

公开(公告)号：US11728012B2

公开(公告)日：2023-08-15

申请号：US17751637

申请日：2022-05-23

Applicant: Colgate-Palmolive Company

Inventor： Iraklis Pappas ,  Bartosz Luczynski ,  Donghui Wu ,  Dong Hyun Kim

IPC: G16C20/30 ,  G16C20/70 ,  G16C20/10

CPC classification number: G16C20/30 ,  G16C20/10 ,  G16C20/70

Abstract: A system, apparatus, and/or method is disclosed for determining a value of a property of a considered chemical composition. An identity of a sample chemical composition may be received. A sample chemical composition may comprise ingredients. Each of the ingredients may be associated with a value of a chemoinformatic property of chemoinformatic properties of the sample chemical composition. A value of a property of the sample chemical composition and at least one of (1) the identity of the sample chemical composition or (2) the values of the chemoinformatic properties of the ingredients of the sample chemical composition may be input into a model. The value of the property of the considered chemical composition may be determined, via the model, based on at least one of (1) an identity of the considered chemical composition or (2) values of chemoinformatic properties of ingredients of the considered chemical composition.

公开(公告)号：US10908099B2

公开(公告)日：2021-02-02

申请号：US16219521

申请日：2018-12-13

Applicant: Colgate-Palmolive Company ,  Northwestern University

Inventor： Michael Fitzgerald ,  Iraklis Pappas ,  Jean-Francois Gaillard ,  Marco Alsina Corvalan

IPC: G01N23/083 ,  G01N21/89 ,  G01N21/94 ,  G01N23/087

Abstract: The disclosure contains a method of quantifying and/or evaluating metal ions in a dentifrice, wherein the method comprises subjecting the dentifrice to X-ray absorption spectroscopy (XAS), and wherein the XAS is used to measure and/or evaluate the metal ions in the dentifrice. Also disclosed are methods of selecting and screening for dentifrices based upon the evaluation and quantification of their metal ion content.

公开(公告)号：US20160106643A1

公开(公告)日：2016-04-21

申请号：US14887774

申请日：2015-10-20

Applicant: Colgate-Palmolive Company

Inventor： John Vaughn ,  Iraklis Pappas ,  Long Pan

IPC: A61K8/26 ,  A61Q15/00 ,  C01F7/00 ,  A61K8/20 ,  A61K8/19 ,  C01F7/56 ,  A61K8/28 ,  A61K8/44

CPC classification number: A61K8/26 ,  A61K8/19 ,  A61K8/20 ,  A61K8/28 ,  A61K8/42 ,  A61K8/44 ,  A61K2800/58 ,  A61Q15/00 ,  C01F7/002 ,  C01F7/56 ,  C01P2002/86 ,  C01P2002/87

Abstract: An antiperspirant active composition comprising an aluminum salt, the aluminum salt (i) having an aluminum to chloride molar ratio of 0.3:1 to 3:1; and (ii) having a species of polyhydroxyoxoaluminum cation detectable it 76 ppm by 27Al NMR that is present in a relative abundance on a 27Al NMR spectrograph that is greater than an other polyhydroxyoxoaluminum cation detectable by 27Al NMR. Also, disclosed are methods of making the antiperspirant active.

Abstract translation: 一种止汗活性组合物，其包含铝盐，所述铝盐（i）的铝与氯化物的摩尔比为0.3:1至3:1; 和（ii）具有聚羟基氧化铝阳离子的物质，其可通过27Al NMR检测到76ppm，其在27Al NMR光谱仪上的相对丰度存在，其大于可通过27Al NMR检测的其它聚羟基氧代铝阳离子。 此外，公开了使止汗剂活性的方法。

公开(公告)号：US20150335551A1

公开(公告)日：2015-11-26

申请号：US14649136

申请日：2012-12-03

Applicant: Colgate-Palmolive Company

Inventor： Ralph Peter Santarpia, III ,  Iraklis Pappas ,  Elizabeth Gittins

IPC: A61K8/44 ,  A61Q11/00 ,  A61K8/55 ,  A61K8/34 ,  A61K8/19

CPC classification number: A61K8/34 ,  A61K8/19 ,  A61K8/44 ,  A61K8/55 ,  A61K2800/28 ,  A61Q11/00

Abstract: Described herein are oral compositions comprising a basic amino acid, in free or salt form, and a sesquiterpene alcohol; and methods of making and using the same.

Abstract translation: 本文描述的是包含游离或盐形式的碱性氨基酸和倍半萜醇的口服组合物; 以及制作和使用它们的方法。

公开(公告)号：US20150297491A1

公开(公告)日：2015-10-22

申请号：US14648359

申请日：2012-12-03

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Iraklis Pappas ,  Jason Nesta ,  Shira Pilch

IPC: A61K8/73 ,  A61Q11/00 ,  A61K8/20

CPC classification number: A61K8/73 ,  A61K8/042 ,  A61K8/20 ,  A61Q11/00 ,  C08B37/006 ,  C08J3/075 ,  C08J3/24 ,  C08J2305/00 ,  C08L5/00

Abstract: Disclosed is a method of manufacturing a fluid gel, the method comprising adding metal cations to the gellant dispersion while retaining the pH at no greater than 3; and adding a pH modifying agent to the gellant dispersion to increase the pH of the gellant dispersion to greater than 3.

Abstract translation: 公开了一种制造流体凝胶的方法，该方法包括将金属阳离子添加到凝胶分散体中，同时保持pH不大于3; 并将pH调节剂加入到胶凝分散体中以将胶凝剂分散体的pH增加至大于3。

公开(公告)号：US20140127151A1

公开(公告)日：2014-05-08

申请号：US14154216

申请日：2014-01-14

Applicant: Colgate-Palmolive Company

Inventor： Iraklis Pappas ,  Michael C. Fitzgerald ,  Long Pan

IPC: A61K8/41 ,  A61K8/42 ,  A61Q15/00 ,  A61K8/26

CPC classification number: A61K8/416 ,  A61K8/26 ,  A61K8/42 ,  A61K8/44 ,  A61K2800/31 ,  A61K2800/58 ,  A61Q15/00

Abstract: A method of producing an anhydrous antiperspirant composition comprising (a) providing a mixture of at least one antiperspirant active including a metal salt, and an anhydrous carrier for the at least one antiperspirant active in which the at least one antiperspirant active is dissolved, the carrier comprising a eutectic mixture of at least one basic compound selected from a basic amide and a basic amine and at least one member chosen from a cation and zwitterion; and (b) heating the mixture to form a stabilized eutectic system of the at least one antiperspirant active and the anhydrous carrier, and wherein the at least one antiperspirant active, the at least one basic compound and the at least one member chosen from a cation and zwitterion form a ternary eutectic system.

Abstract translation: 一种制备无水止汗组合物的方法，其包含（a）提供至少一种止汗剂活性物质（包括金属盐）的混合物和至少一种其中所述至少一种止汗活性剂溶解的止汗活性剂的无水载体，所述载体 包括至少一种选自碱性酰胺和碱性胺的碱性化合物和选自阳离子和两性离子的至少一种的共晶混合物; 和（b）加热所述混合物以形成所述至少一种止汗活性剂和所述无水载体的稳定的共晶体系，并且其中所述至少一种止汗活性剂，所述至少一种碱性化合物和至少一种选自阳离子 并且两性离子形成三元共晶体系。