Animal cell colony picking apparatus and method
    21.
    发明申请
    Animal cell colony picking apparatus and method 有权
    动物细胞集落采摘装置及方法

    公开(公告)号:US20090116714A1

    公开(公告)日:2009-05-07

    申请号:US12318612

    申请日:2009-01-02

    Abstract: An apparatus and method for automated picking of animal cell colonies. A picking head comprising a plurality of hollow pins is provided. The apparatus has an integrated imager for capturing an image of adherent or non-adherent animal cell colonies held in liquid or semi-solid medium. Image processing identifies the locations of the animal cell colonies to be picked. Picking an animal cell colony is performed by aligning each of the hollow pins in turn with a target animal cell colony location, introducing the hollow pin into the medium, and aspirating the animal cell colony into the hollow pin. In the case of an adherent colony, the distal end of the pin is forced into oscillation to detach the animal cell colony prior to aspiration. The animal cell colony is dispensed into a well plate by increasing pressure in the fluid conduit.

    Abstract translation: 用于自动采集动物细胞集落的装置和方法。 提供包括多个中空销的拾取头。 该装置具有用于捕获保持在液体或半固体培养基中的贴壁或非粘附动物细胞集落的图像的集成成像器。 图像处理识别待挑选的动物细胞集落的位置。 通过将每个中空针依次与目标动物细胞集落位置对准,将中空销引入培养基中,并将动物细胞集落吸入中空销来进行动物细胞集落的采摘。 在附着菌落的情况下,引脚的远端被迫振荡以在抽吸之前分离动物细胞集落。 通过增加流体导管中的压力将动物细胞集落分配到孔板中。

    Millimetre and sub-millimetre imaging device
    24.
    发明申请
    Millimetre and sub-millimetre imaging device 失效
    毫米和亚毫米成像装置

    公开(公告)号:US20070029483A1

    公开(公告)日:2007-02-08

    申请号:US10571901

    申请日:2004-09-15

    CPC classification number: G01V8/005

    Abstract: The terahertz camera has a fixed objective lens (2) and a plurality of detectors (3) positioned at the focal plane of the objective lens (2). Each of the detectors (3) is mounted on a movable support (10) so that the antenna is capable of movement across the focal plane of the objective lens (2) and is provided with a flexible waveguide (4) for connecting the output of the detector (3) with signal processing means. Each detector (3) is also provided with a retroreflector (6) which is reflective at frequencies other than terahertz frequencies. During use of the camera, the retroreflector (6) of each detector (3) is illuminated at non-terahertz frequencies so that the spatial position of each detector (3) and hence the spatial source of signals generated by the detector can be accurately identified. The terahertz camera is particularly suited for use in security installations and in chemical and food processing industries.

    Abstract translation: 太赫兹相机具有固定物镜(2)和位于物镜(2)的焦平面处的多个检测器(3)。 每个检测器(3)安装在可移动支撑件(10)上,使得天线能够移动穿过物镜(2)的焦平面,并且设置有柔性波导(4),用于将 具有信号处理装置的检测器(3)。 每个检测器(3)还设置有后向反射器(6),反射器以不同于太赫兹频率的频率反射。 在使用相机期间,每个检测器(3)的后向反射器(6)以非太赫兹频率被照射,使得每个检测器(3)的空间位置以及因此可以准确地识别检测器产生的信号的空间信号源 。 太赫兹相机特别适用于安全装置和化学和食品加工业。

    Animal cell colony picking apparatus and method
    26.
    发明授权
    Animal cell colony picking apparatus and method 有权
    动物细胞集落采摘装置及方法

    公开(公告)号:US08293520B2

    公开(公告)日:2012-10-23

    申请号:US13267707

    申请日:2011-10-06

    Abstract: Animal cell colonies are picked up automatically by an apparatus having a picking head with a plurality of hollow pins and an integrated imager for capturing an image of adherent or non-adherent animal cell colonies held in liquid or semi-solid medium. Image processing identifies the locations of the animal cell colonies to be picked. Picking an animal cell colony is performed by aligning each of the hollow pins in turn with a target animal cell colony location, introducing the hollow pin into the medium, and aspirating the animal cell colony into the hollow pin. In the case of an adherent colony, the distal end of the pin is forced into oscillation to detach the animal cell colony prior to aspiration. The animal cell colony is dispensed into a well plate by increasing pressure in the fluid conduit.

    Abstract translation: 动物细胞集落通过具有多个中空针头的拾取头的装置自动拾取,以及用于捕获保持在液体或半固体培养基中的贴壁或非贴壁动物细胞集落的图像的集成成像器。 图像处理识别待挑选的动物细胞集落的位置。 通过将每个中空针依次与目标动物细胞集落位置对准,将中空销引入培养基中,并将动物细胞集落吸入中空销来进行动物细胞集落的采摘。 在附着菌落的情况下,引脚的远端被迫振荡以在抽吸之前分离动物细胞集落。 通过增加流体导管中的压力将动物细胞集落分配到孔板中。

    Animal cell colony picking apparatus and method
    29.
    发明授权
    Animal cell colony picking apparatus and method 有权
    动物细胞集落采摘装置及方法

    公开(公告)号:US08034625B2

    公开(公告)日:2011-10-11

    申请号:US11401966

    申请日:2006-04-12

    Abstract: An apparatus and method for automated picking of animal cell colonies is described. A picking head comprising a plurality of hollow pins is provided. The apparatus has an integrated imager for capturing an image of adherent or non-adherent animal cell colonies held in liquid or semi-solid medium. Image processing identifies the locations of the animal cell colonies to be picked. Picking an animal cell colony is performed by aligning each of the hollow pins in turn with a target animal cell colony location, introducing the hollow pin into the medium, and aspirating the animal cell colony into the hollow pin. In the case of an adherent colony, the distal end of the pin is forced into oscillation to detach the animal cell colony prior to aspiration. The animal cell colony is dispensed into a well plate by increasing pressure in the fluid conduit.

    Abstract translation: 描述了用于动物细胞集落的自动采集的装置和方法。 提供包括多个中空销的拾取头。 该装置具有用于捕获保持在液体或半固体培养基中的贴壁或非粘附动物细胞集落的图像的集成成像器。 图像处理识别待挑选的动物细胞集落的位置。 通过将每个中空针依次与目标动物细胞集落位置对准,将中空销引入培养基中,并将动物细胞集落吸入中空销来进行动物细胞集落的采摘。 在附着菌落的情况下,引脚的远端被迫振荡以在抽吸之前分离动物细胞集落。 通过增加流体导管中的压力将动物细胞集落分配到孔板中。

Patent Agency Ranking