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公开(公告)号:US11096781B2
公开(公告)日:2021-08-24
申请号:US15664430
申请日:2017-07-31
Applicant: Edwards Lifesciences Corporation
Inventor: Nikolay Gurovich , Michael Bukin , Elena Sherman , Tamir S. Levi , Ziv Yohanan , Gil Senesh , Dikla Kersh , Alexey M. Tsypenyuk , Waina Michelle Chu , Alexander Barash
IPC: A61F2/24
Abstract: A prosthetic heart valve can include a radially collapsible and expandable annular frame having a plurality of struts defining openings. The prosthetic heart valve can further include a plurality of leaflets that regulate the flow of blood through the frame. The prosthetic heart valve can also include a sealing member mounted on the frame and having an inner layer and an outer layer. At least the outer layer is mounted on the outside of the frame, and the inner layer covers at least the openings in the frame between adjacent cusp portions of adjacent leaflets and the inner layer does not cover one or more openings in the frame at locations facing the outflow surfaces of the leaflets to permit retrograde blood to flow through the one or more uncovered openings in the frame and into space between the outer layer and the frame.
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公开(公告)号:US20200205964A1
公开(公告)日:2020-07-02
申请号:US16799741
申请日:2020-02-24
Applicant: Edwards Lifesciences Corporation
Inventor: Tomer Saar , Michael Bukin , Elena Sherman , Alexander Barash , Yana Mayatskaya
IPC: A61F2/24
Abstract: An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration includes an annular frame including a plurality of angled strut members, and a skirt member secured to the frame. The skirt member includes a plurality of extension portions wrapped around at least one strut member adjacent the extension portions. The prosthetic valve further includes a cord member threaded through at least a portion of the plurality of extension portions to secure the skirt member to the at least one strut member.
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公开(公告)号:US10575944B2
公开(公告)日:2020-03-03
申请号:US15709355
申请日:2017-09-19
Applicant: Edwards Lifesciences Corporation
Inventor: Tomer Saar , Michael Bukin , Elena Sherman , Alexander Barash , Yana Mayatskaya
IPC: A61F2/24
Abstract: An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration includes an annular frame including a plurality of angled strut members, and a skirt member secured to the frame. The skirt member includes a plurality of extension portions wrapped around at least one strut member adjacent the extension portions. The prosthetic valve further includes a cord member threaded through at least a portion of the plurality of extension portions to secure the skirt member to the at least one strut member.
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公开(公告)号:US20190021834A1
公开(公告)日:2019-01-24
申请号:US16036190
申请日:2018-07-16
Applicant: Edwards Lifesciences Corporation
Inventor: Noam Nir , Carmel Peleg , Tomer Saar , Alexander Barash , David Maimon
Abstract: Disclosed herein is a storage container for an expandable prosthetic heart valve that crimps the valve upon opening the container and removal of the valve from the container. The container includes a housing sized to receive the heart valve in its expanded configuration and a crimping mechanism. The crimping mechanism is incorporated into the container and engages the heart valve so as to operably convert the heart valve from its expanded configuration to its smaller crimped configuration upon opening the container and removing the valve.
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公开(公告)号:US20180344456A1
公开(公告)日:2018-12-06
申请号:US15995528
申请日:2018-06-01
Applicant: Edwards Lifesciences Corporation
Inventor: Alexander Barash , Yair A. Neumann , Tomer Saar , Ziv Yohanan , Noam Nir
IPC: A61F2/24
Abstract: In one embodiment, a prosthetic valve can comprise a radially expandable and compressible frame, which can include a plurality of struts which are pivotally joined together without requiring individual rivets. In some embodiments, the struts are interwoven, and can be joined using integral hinges formed in the struts, such as by performing alternate cuts on the struts, bending the struts to form stopper tabs adjacent to joints and/or drilling holes in the struts to facilitate interconnecting struts at joints, or otherwise forming integral hinges and corresponding holes at junction points between the struts. In another embodiment, the frame comprises a plurality of inner struts and outer struts which are connected by a plurality of chains of interconnected rivets, avoiding the need to provide individual rivets at each junction between struts. In still another embodiment, separate hinges are provided to interconnect the struts. In still another embodiment, separate flanged rivets are provided to connect the struts.
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公开(公告)号:US20180078367A1
公开(公告)日:2018-03-22
申请号:US15709355
申请日:2017-09-19
Applicant: Edwards Lifesciences Corporation
Inventor: Tomer Saar , Michael Bukin , Elena Sherman , Alexander Barash , Yana Mayatskaya
IPC: A61F2/24
Abstract: An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration includes an annular frame including a plurality of angled strut members, and a skirt member secured to the frame. The skirt member includes a plurality of extension portions wrapped around at least one strut member adjacent the extension portions. The prosthetic valve further includes a cord member threaded through at least a portion of the plurality of extension portions to secure the skirt member to the at least one strut member.
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公开(公告)号:US12290436B2
公开(公告)日:2025-05-06
申请号:US17316885
申请日:2021-05-11
Applicant: Edwards Lifesciences Corporation
Inventor: Nikolai Gurovich , Michael Bukin , Elena Sherman , Tamir S. Levi , Ziv Yohanan , Gil Senesh , Dikla Kersh , Alexey Tsypenyuk , Waina Michelle Chu , Alexander Barash
Abstract: A prosthetic heart valve can include a radially expandable and compressible frame having an inflow end portion and an outflow end portion, the frame comprising a plurality of struts defining openings between them. The prosthetic valve can further include a valvular structure comprising a plurality of leaflets, each leaflet comprising a main body, opposing tabs on opposite sides of the main body, a coaptation edge portion, and a cusp edge portion. Each tab can be paired with an adjacent tab of an adjacent leaflet to form a plurality of commissures that are fixed relative to the frame, and each leaflet can have opposing edge portions between the opposing tabs and the cusp edge portion that are unattached to the frame, each unattached edge portion defining a gap that extends radially into the main body of the leaflet.
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公开(公告)号:US12226312B2
公开(公告)日:2025-02-18
申请号:US18316942
申请日:2023-05-12
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Nikolai Gurovich , Michael Bukin , Elena Sherman , Tamir S. Levi , Ziv Yohanan , Gil Senesh , Dikla Kersh , Alexey Tsypenyuk , Waina Michelle Chu , Alexander Barash
Abstract: A prosthetic heart valve can include a radially expandable and compressible frame having an inflow end, an outflow end, and a plurality of struts. The prosthetic valve can further include a valvular structure comprising a plurality of leaflets, each leaflet comprising a coaptation edge portion and a cusp edge portion. The cusp edge portion of each leaflet can be folded toward the outflow end of the frame along a bending axis and a reinforcing member extends along an outflow surface of the cusp edge portion along the bending axis. The prosthetic heart valve can include a plurality of connecting skirts, each disposed between the cusp edge portion of an adjacent leaflet and the frame. First stitching secures the reinforcing member and the connecting skirts to the cusp edge portions and second stitching secures the connecting skirts to selected struts of the frame.
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公开(公告)号:US12201522B2
公开(公告)日:2025-01-21
申请号:US18207822
申请日:2023-06-09
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Alexander Barash , Yair A. Neumann , Tomer Saar , Ziv Yohanan , Noam Nir
Abstract: In one embodiment, a method of assembling a prosthetic valve can comprise forming a radially expandable and compressible frame by pivotally joining together a plurality of struts without requiring individual rivets. In some embodiments, the frame is formed by interweaving the struts, which can be joined using integral hinges formed in the struts, such as by performing alternate cuts on the struts, bending the struts to form stopper tabs adjacent to joints and/or drilling holes in the struts to facilitate interconnecting struts at joints, or otherwise forming integral hinges and corresponding holes at junction points between the struts. In other embodiments, separate hinges are provided to interconnect the struts. In still other embodiments, separate flanged rivets are provided to connect the struts.
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公开(公告)号:US20240415645A1
公开(公告)日:2024-12-19
申请号:US18817003
申请日:2024-08-27
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Alexander Barash , Yair A. Neumann , Tomer Saar , Ziv Yohanan , Noam Nir
Abstract: In one embodiment, a method of assembling a prosthetic valve can comprise forming a radially expandable and compressible frame by pivotally joining together a plurality of struts without requiring individual rivets. In some embodiments, the frame is formed by interweaving the struts, which can be joined using integral hinges formed in the struts, such as by performing alternate cuts on the struts, bending the struts to form stopper tabs adjacent to joints and/or drilling holes in the struts to facilitate interconnecting struts at joints, or otherwise forming integral hinges and corresponding holes at junction points between the struts. In other embodiments, separate hinges are provided to interconnect the struts. In still other embodiments, separate flanged rivets are provided to connect the struts.
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