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公开(公告)号：US20220296775A1
公开(公告)日：2022-09-22
申请号：US17806430
申请日：2022-06-10
发明人： Manouchehr A. Miraki , Jingjia Han , Bin Tian , Angela B. De La Fuente , Liqiong Gui , Hao Shang , Lien Huong Thi Hoang , Vicky Hong Do
摘要： An annuloplasty ring prosthesis comprising a frame having an outer surface; and a cover surrounding the frame. The cover comprises a bioprosthetic tissue that can be regenerative or fixed and non-regenerative. The frame can be bioabsorbable or non-degradable. A ring prosthesis and a method of manufacturing a ring prosthesis is also provided. The ring prosthesis comprising an elongated rod member formed into a substantially ring shape, the elongated rod member being formed substantially from a flat bioprosthetic tissue.
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公开(公告)号：US20220218483A1
公开(公告)日：2022-07-14
申请号：US17656840
申请日：2022-03-28
发明人： Sven Benjamin Iversen , Adam J. Yestrepsky , Amy E. Munnelly , Bin Tian , Danny Barrientos Baldo , Brian S. Conklin , Louis A. Campbell , John Richard Carpenter , Derrick Johnson
摘要： A tissue anchor delivery includes comprises a needle including a hollow shaft portion, a tip portion, and an outlet opening. The tissue anchor delivery device further includes a plurality of tissue anchors disposed within the shaft portion of the needle and a suture coupled to each of the plurality of tissue anchors and disposed at least partially within the shaft portion of the needle.
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公开(公告)号：US20200000586A1
公开(公告)日：2020-01-02
申请号：US16570797
申请日：2019-09-13
IPC分类号： A61F2/24
摘要： Systems, devices, kits, and methods are described for securing a bioprosthetic heart valve within an anatomical feature of a patient. Kits can comprise a bioprosthetic heart valve, a curable composition, and an applicator configured to deliver the curable composition to a target area. The bioprosthetic heart valve can comprise a support structure and one or more valve leaflets coupled thereto. The support structure can comprise a sewing portion peripheral of the bioprosthetic heart valve. The support structure and the valve leaflets can define a central flow orifice. The curable composition can comprise a pre-polymer composition and an initiator. Methods can comprise positioning the bioprosthetic heart valve within the anatomical feature of a patient, applying the curable composition to one or both of the bioprosthetic heart valve and the anatomical feature, and curing the curable composition for a cure time. The applying can be performed before or after the positioning.
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公开(公告)号：US20170071731A1
公开(公告)日：2017-03-16
申请号：US15357990
申请日：2016-11-21
发明人： Jeffrey S. Dove , Bin Tian , Ralph Schneider , Jeffrey S. Cohen , Ivan Jankovic , John F. Migliazza , Gregory A. Wright , James M. Young , Louis A. Campbell
CPC分类号： A61F2/2415 , A61B18/20 , A61F2/02 , A61F2/24 , A61F2/2409 , A61F2/2418 , A61F2002/30324 , A61F2250/0036 , A61L27/3604 , A61L27/3625 , A61L27/3691 , A61L27/507 , A61L2300/60 , A61L2430/20 , B65B55/18 , B65B63/02
摘要： Methods for the conditioning of bioprosthetic material employ bovine pericardial membrane. A laser directed at the fibrous surface of the membrane and moved relative thereto reduces the thickness of the membrane to a specific uniform thickness and smoothes the surface. The wavelength, power and pulse rate of the laser are selected which will smooth the fibrous surface as well as ablate the surface to the appropriate thickness. Alternatively, a dermatome is used to remove a layer of material from the fibrous surface of the membrane. Thinning may also employ compression. Stepwise compression with cross-linking to stabilize the membrane is used to avoid damaging the membrane through inelastic compression. Rather, the membrane is bound in the elastic compressed state through addition cross-linking. The foregoing several thinning techniques may be employed together to achieve strong thin membranes.
摘要翻译： 生物假体材料调理方法采用牛心包膜。 指向膜的纤维表面并相对于其移动的激光将膜的厚度减小到特定的均匀厚度并平滑表面。 选择激光器的波长，功率和脉冲速率，这将使纤维表面平滑，并将表面烧蚀到合适的厚度。 或者，使用皮肤表面从膜的纤维表面去除一层材料。 变薄也可能采用压缩。 使用交联以稳定膜的逐步压缩来避免通过非弹性压缩损伤膜。 相反，膜通过加成交联结合在弹性压缩状态。 上述几种稀释技术可以一起使用以获得强的薄膜。
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公开(公告)号：US09498288B2
公开(公告)日：2016-11-22
申请号：US13950154
申请日：2013-07-24
发明人： Jeffrey S. Dove , Bin Tian , Ralph Schneider , Jeffrey S. Cohen , Ivan Jankovic , John F. Migliazza , Gregory A. Wright , James Young , Louis A. Campbell
CPC分类号： A61F2/2415 , A61B18/20 , A61F2/02 , A61F2/24 , A61F2/2409 , A61F2/2418 , A61F2002/30324 , A61F2250/0036 , A61L27/3604 , A61L27/3625 , A61L27/3691 , A61L27/507 , A61L2300/60 , A61L2430/20 , B65B55/18 , B65B63/02
摘要： Methods for the conditioning of bioprosthetic material employ bovine pericardial membrane. A laser directed at the fibrous surface of the membrane and moved relative thereto reduces the thickness of the membrane to a specific uniform thickness and smoothes the surface. The wavelength, power and pulse rate of the laser are selected which will smooth the fibrous surface as well as ablate the surface to the appropriate thickness. Alternatively, a dermatome is used to remove a layer of material from the fibrous surface of the membrane. Thinning may also employ compression. Stepwise compression with cross-linking to stabilize the membrane is used to avoid damaging the membrane through inelastic compression. Rather, the membrane is bound in the elastic compressed state through addition cross-linking. The foregoing several thinning techniques may be employed together to achieve strong thin membranes.
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公开(公告)号：US09492230B2
公开(公告)日：2016-11-15
申请号：US13621680
申请日：2012-09-17
发明人： Ralph Schneider , Bin Tian , Jeffrey S. Dove , Jeff Cohen , Ivan Jankovic , John F. Migliazza , Gregory A. Wright , James Young , Louis A. Campbell
CPC分类号： A61F2/2415 , A61B18/20 , A61F2/02 , A61F2/24 , A61F2/2409 , A61F2/2418 , A61F2002/30324 , A61F2250/0036 , A61L27/3604 , A61L27/3625 , A61L27/3691 , A61L27/507 , A61L2300/60 , A61L2430/20 , B65B55/18 , B65B63/02
摘要： Methods for the conditioning of bioprosthetic material employ bovine pericardial membrane. A laser directed at the fibrous surface of the membrane and moved relative thereto reduces the thickness of the membrane to a specific uniform thickness and smoothes the surface. The wavelength, power and pulse rate of the laser are selected which will smooth the fibrous surface as well as ablate the surface to the appropriate thickness. Alternatively, a dermatome is used to remove a layer of material from the fibrous surface of the membrane. Thinning may also employ compression. Stepwise compression with cross-linking to stabilize the membrane is used to avoid damaging the membrane through inelastic compression. Rather, the membrane is bound in the elastic compressed state through addition cross-linking. The foregoing several thinning techniques may be employed together to achieve strong thin membranes.
摘要翻译： 生物假体材料调理方法采用牛心包膜。 指向膜的纤维表面并相对于其移动的激光将膜的厚度减小到特定的均匀厚度并平滑表面。 选择激光器的波长，功率和脉冲速率，这将使纤维表面平滑，并将表面烧蚀到合适的厚度。 或者，使用皮肤表面从膜的纤维表面去除一层材料。 变薄也可能采用压缩。 使用交联以稳定膜的逐步压缩来避免通过非弹性压缩损伤膜。 相反，膜通过加成交联结合在弹性压缩状态。 上述几种稀释技术可以一起使用以获得强的薄膜。
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公开(公告)号：US20140260097A1
公开(公告)日：2014-09-18
申请号：US14211775
申请日：2014-03-14
发明人： Neal Avery , Hao Shang , Julie A. Benton , Bin Tian
CPC分类号： A61F2/2427 , A61F2/24 , A61F2/2433 , A61F2/2436 , A61F2002/9522
摘要： The present disclosure is directed to embodiments of automated crimping systems, methods of crimping prosthetic valves, and methods of using automated crimping systems to crimp prosthetic valves. In some embodiments, an automated crimping system includes a crimper controller, a rotary actuator, an outer crimper housing, and a crimper mechanism mounted within the outer crimper housing. In some embodiments, an automated method of crimping a prosthetic valve includes inserting a prosthetic valve into an automated crimping system, activating the automated crimping system, and removing the crimped prosthetic valve from the automated crimping system. In some embodiments, a method of crimping a prosthetic valve comprises partially crimping the prosthetic valve at a first speed to a partially crimped configuration and further crimping the prosthetic valve at a second speed.
摘要翻译： 本公开涉及自动压接系统的实施例，卷曲人造瓣膜的方法以及使用自动压接系统卷曲人造瓣膜的方法。 在一些实施例中，自动压接系统包括压接机控制器，旋转致动器，外部压接器壳体和安装在外部压接器壳体内的压接机构。 在一些实施例中，压接人工瓣膜的自动化方法包括将人造瓣膜插入自动压接系统中，启动自动压接系统，以及从自动压接系统移除卷曲的假体瓣膜。 在一些实施例中，压接人工瓣膜的方法包括以第一速度部分地将人造瓣膜压接到部分压接构造并且以第二速度进一步压接人造瓣膜。
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公开(公告)号：US20240033489A1
公开(公告)日：2024-02-01
申请号：US18379539
申请日：2023-10-12
发明人： Pu Zhou , Bin Tian , Yidong M. Zhu
IPC分类号： A61M25/10 , B23K26/362 , B23K26/402 , B23K26/0622 , B23K26/361 , B21D39/00 , B23K26/06
CPC分类号： A61M25/1029 , B23K26/362 , B23K26/402 , B23K26/0624 , B23K26/361 , B21D39/00 , B23K26/0626 , A61M2025/1031 , A61M2025/1086 , B23K2103/42
摘要： Inflatable devices are disclosed including a surface which has a network of polymer chains and is configured to be inflatable into a therapeutically or diagnostically useful shape, and at least one ultrashort laser pulse-formed modification in the surface. The network can, for example, include a network morphology that is substantially unchanged by modification with the ultrashort pulse laser. Ultrashort laser pulses can be laser pulses equal to or less than 1000 picoseconds in duration. Advantageously, the etching process uses a relatively low-heat laser to avoid significant heating of surrounding polymers while modifying the surface (and other structures) of the device. The process is configured so that the polymer chain morphology adjacent the modification is substantially unaffected by the low-heat laser. The resulting inflatable device has customized surface features while still retaining substantially homogenous polymer network morphology. This preserves the elasticity, especially the surface elasticity, of the inflatable device.
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公开(公告)号：US20220338982A1
公开(公告)日：2022-10-27
申请号：US17811545
申请日：2022-07-08
IPC分类号： A61F2/24
摘要： Systems, devices, kits, and methods are described for securing a bioprosthetic heart valve within an anatomical feature of a patient. Kits can comprise a bioprosthetic heart valve, a curable composition, and an applicator configured to deliver the curable composition to a target area. The bioprosthetic heart valve can comprise a support structure and one or more valve leaflets coupled thereto. The support structure can comprise a sewing portion peripheral of the bioprosthetic heart valve. The support structure and the valve leaflets can define a central flow orifice. The curable composition can comprise a pre-polymer composition and an initiator. Methods can comprise positioning the bioprosthetic heart valve within the anatomical feature of a patient, applying the curable composition to one or both of the bioprosthetic heart valve and the anatomical feature, and curing the curable composition for a cure time. The applying can be performed before or after the positioning.
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公开(公告)号：US20220117730A1
公开(公告)日：2022-04-21
申请号：US17645936
申请日：2021-12-23
发明人： Jeffrey S. Dove , Bin Tian , Ralph Schneider , Jeffrey S. Cohen , Ivan Jankovic , John F. Migliazza , Gregory A. Wright , James M. Young , Louis A. Campbell
摘要： Methods for the conditioning of bioprosthetic material employ bovine pericardial membrane. A laser directed at the fibrous surface of the membrane and moved relative thereto reduces the thickness of the membrane to a specific uniform thickness and smooths the surface. The wavelength, power and pulse rate of the laser are selected which will smooth the fibrous surface as well as ablate the surface to the appropriate thickness. Alternatively, a dermatome is used to remove a layer of material from the fibrous surface of the membrane. Thinning may also employ compression. Stepwise compression with cross-linking to stabilize the membrane is used to avoid damaging the membrane through inelastic compression. Rather, the membrane is bound in the elastic compressed state through addition cross-linking. The foregoing several thinning techniques may be employed together to achieve strong thin membranes.
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