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    System and method for transaortic delivery of a prosthetic heart valve
    21.
    发明授权
    System and method for transaortic delivery of a prosthetic heart valve 有权

    公开(公告)号：US10149757B2

    公开(公告)日：2018-12-11

    申请号：US14215399

    申请日：2014-03-17

    Applicant: Edwards Lifesciences Corporation

    Inventor： Mark Dehdashtian ,  Teodoro S. Jimenez

    IPC: A61F2/24

    Abstract: A delivery system and method for delivering a prosthetic heart valve to the aortic valve annulus via a transaortic approach. The system includes a balloon catheter for delivering a balloon-expandable prosthetic heart valve through an introducer from an approach from outside the patient, through a minimally-invasive opening in the chest cavity through an incision in the aorta, and into the aorta and aortic annulus. The balloon catheter includes a flexible, tapered tip just distal of the balloon to facilitate positioning of the prosthetic heart valve in the proper orientation within the aortic annulus. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized.

    Aortic occlusion device
    22.
    发明授权
    Aortic occlusion device 有权

    公开(公告)号：US10130371B2

    公开(公告)日：2018-11-20

    申请号：US14276795

    申请日：2014-05-13

    Applicant: Edwards Lifesciences Corporation

    Inventor： Mark Dehdashtian ,  Teodoro S. Jimenez ,  Nathan Satter ,  Fabian D. Schroeder ,  Raffaele Mazzei ,  Jeff Kosmoski ,  Shaun Zamani ,  Adam Yestrepsky

    IPC: A61B17/12 ,  A61M1/34 ,  A61M1/36 ,  A61F2/01

    Abstract: Embodiments of aortic occlusion devices are described herein that include radially expandable and collapsible proximal and distal end portions, such as annular self-expanding stents or frames, that are configured to radially expand within an aorta to secure the device within the aorta. The devices can also include a catheter extending axially between the distal end portion and the proximal end portion and a porous covering, or filter, positioned around the catheter and between the proximal end portion and the distal end portion and configured to filter emboli from blood flowing into upper-body arteries. The device can further include a one-way valve positioned at or adjacent to the distal end portion of the device and configured to restrict retrograde blood flow through the device toward the heart.

    AORTIC OCCLUSION DEVICE
    26.
    发明申请
    AORTIC OCCLUSION DEVICE 审中-公开

    公开(公告)号：US20140350523A1

    公开(公告)日：2014-11-27

    申请号：US14276795

    申请日：2014-05-13

    Applicant: EDWARDS LIFESCIENCES CORPORATION

    Inventor： Mark Dehdashtian ,  Teodoro S. Jimenez ,  Nathan Satter ,  Fabian D. Schroeder ,  Raffaele Mazzei ,  Jeff Kosmoski ,  Shaun Zamani ,  Adam Yestrepsky

    IPC: A61B17/12 ,  A61M1/34 ,  A61M1/36

    CPC classification number: A61B17/12109 ,  A61B17/1204 ,  A61B17/12122 ,  A61B17/12136 ,  A61B17/12145 ,  A61B17/1215 ,  A61F2/01 ,  A61F2002/011 ,  A61M1/34 ,  A61M1/3666 ,  A61M2205/3331

    Abstract: Embodiments of aortic occlusion devices are described herein that include radially expandable and collapsible proximal and distal end portions, such as annular self-expanding stents or frames, that are configured to radially expand within an aorta to secure the device within the aorta. The devices can also include a catheter extending axially between the distal end portion and the proximal end portion and a porous covering, or filter, positioned around the catheter and between the proximal end portion and the distal end portion and configured to filter emboli from blood flowing into upper-body arteries. The device can further include a one-way valve positioned at or adjacent to the distal end portion of the device and configured to restrict retrograde blood flow through the device toward the heart.

    Abstract translation: 本文描述了主动脉闭塞装置的实施例，其包括径向可膨胀和可收缩的近端部分和远端部分，例如环形自扩张支架或框架，其构造成在主动脉内径向扩张以将装置固定在主动脉内。 所述装置还可以包括在远端部分和近端部分之间轴向延伸的导管和位于导管周围并且位于近端部分和远端部分之间的多孔覆盖物或过滤器，并且构造成将血栓从血流过滤 进入上半身动脉。 该装置还可以包括位于装置的远端部分处或邻近装置的远端部分的单向阀，并且构造成限制逆流血流通过装置朝向心脏。

    METHODS OF VALVE DELIVERY ON A BEATING HEART
    27.
    发明申请
    METHODS OF VALVE DELIVERY ON A BEATING HEART 有权
    阀门输送方法

    公开(公告)号：US20130345798A1

    公开(公告)日：2013-12-26

    申请号：US13922129

    申请日：2013-06-19

    Applicant: Edwards Lifesciences Corporation

    Inventor： Teodoro S. Jimenez ,  Walter Lee ,  Mark Dehdashtian ,  Kristopher J. Yee

    IPC: A61F2/24

    CPC classification number: A61F2/2427 ,  A61F2/24 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/243 ,  A61F2/2433 ,  A61F2220/0016 ,  A61F2220/005 ,  A61M25/0133 ,  A61M25/0136 ,  A61M25/0138 ,  A61M25/0141 ,  A61M25/0144 ,  A61M25/0147 ,  A61M2025/015

    Abstract: A delivery system and method for delivering a prosthetic heart valve to the aortic valve annulus. The system includes a delivery catheter having a steering mechanism thereon for delivering a balloon-expandable prosthetic heart valve to the aortic annulus in an antegrade fashion through an introducer passing into the left ventricle through its apex. The introducer may have a more floppy distal section than a proximal section to reduce trauma to the heart wall while preserving good operating field stability. The delivery catheter includes a deflecting segment just proximal to a distal balloon to facilitate positioning of the prosthetic heart valve in the proper orientation within the aortic annulus. A trigger in a catheter handle may be coupled to a deflection wire that actuates the deflecting segment, while a slider in the handle controls retraction of a valve pusher. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized.

    Abstract translation: 用于将假体心脏瓣膜递送到主动脉瓣环的输送系统和方法。 该系统包括具有其上的转向机构的输送导管，用于通过穿过其顶点进入左心室的导引器以顺行方式将球囊可扩张的假体心脏瓣膜递送至主动脉环。 导引器可以具有比近端部分更软的远侧部分，以减少对心脏壁的创伤，同时保持良好的操作场稳定性。 输送导管包括刚好靠近远端气囊的偏转部分，以便于在主动脉瓣环内的正确取向中定位假体心脏瓣膜。 导管手柄中的触发器可以联接到致动偏转段的偏转线，而手柄中的滑块控制阀推动器的缩回。 假体心脏瓣膜可以安装在现有的钙化小叶上，并且还可以使用预扩张瓣膜成形术程序。

    SYSTEMS OF HEART VALVE DELIVERY
    29.
    发明申请
    SYSTEMS OF HEART VALVE DELIVERY 有权

    公开(公告)号：US20230025110A1

    公开(公告)日：2023-01-26

    申请号：US17958105

    申请日：2022-09-30

    Applicant: Edwards Lifesciences Corporation

    Inventor： Teodoro S. Jimenez ,  Walter Lee ,  Mark M. Dehdashtian ,  Kristopher J. Yee

    IPC: A61F2/24 ,  A61M25/01

    Abstract: A delivery system and method for delivering a prosthetic heart valve to the aortic valve. The system includes a delivery catheter having a steering mechanism thereon for delivering a balloon-expandable prosthetic heart valve to the aortic valve through an introducer passing into the left ventricle through its apex. The introducer may have a more floppy distal section than a proximal section to reduce trauma to the heart wall while preserving good operating field stability. The delivery catheter includes a deflecting segment just proximal to a distal balloon to facilitate positioning of the prosthetic heart valve in the proper orientation. A trigger in a catheter handle may be coupled to a deflection wire that actuates the deflecting segment, while a slider in the handle controls retraction of a valve pusher. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized.

    Collapsible cardiac implant and deployment system
    30.
    发明授权
    Collapsible cardiac implant and deployment system 有权

    公开(公告)号：US11446139B2

    公开(公告)日：2022-09-20

    申请号：US16726106

    申请日：2019-12-23

    Applicant: Edwards Lifesciences Corporation

    Inventor： Teodoro S. Jimenez ,  Mark M. Dehdashtian ,  Raffaele Mazzei

    IPC: A61F2/24

    Abstract: A collapsible device, such as an annuloplasty ring or prosthetic heart valve, is configured to be collapsed prior to being introduced into a patient via minimally-invasive access points such as port holes or intercostal incisions. A holder is configured to hold the collapsible device, and to selectively collapse the device for introduction into the patient and then re-enlarge the device at the desired deployment site. Collapsible devices include devices that can hingedly fold about hinge lines, and devices that can elongate to form substantially spiral forms with reduced diameters.

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