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公开(公告)号：US08478392B2
公开(公告)日：2013-07-02
申请号：US13168481
申请日：2011-06-24
IPC分类号： A61B5/04
CPC分类号： A61N1/36514 , A61B5/02133 , A61B5/026 , A61N1/08 , A61N1/36142 , A61N1/36578
摘要： Systems and methods for rhythm discrimination using the motion of an implantable lead are described. In an example, an implantable medical device can include a receiver circuit configured to be electrically coupled to an implantable lead and be configured to obtain information indicative of a movement of the implantable lead due at least in part to a motion of a heart. The device can include an arrhythmia detection circuit configured to determine an arrhythmia status using the information indicative of the movement of the implantable lead and an arrhythmia classification circuit configured to determine one or more of a location or a type of an arrhythmia, using the information indicative of the movement of the implantable lead, when the arrhythmia status indicates that an arrhythmia is occurring or has occurred.
摘要翻译： 描述使用可植入引线的运动进行节律辨别的系统和方法。 在一个示例中，可植入医疗设备可以包括被配置为电耦合到可植入引线的接收器电路，并且被配置为获得至少部分地基于心脏的运动而指示可植入引线的运动的信息。 该装置可以包括心律失常检测电路，其被配置为使用指示可植入引线的移动的信息来确定心律失常状态，以及心律失常分类电路，其被配置为使用所述信息指示来确定心律不齐的位置或类型中的一个或多个 当心律失常状态表示发生心律失常或发生心律失常时，可植入性铅的运动。
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22.发明申请CARDIAC MECHANICAL VIBRATION MONITOR USING INFORMATION INDICATIVE OF LEAD MOTION 有权使用信号指示铅运动的心脏机械振动监测器公开(公告)号：US20110319782A1
公开(公告)日：2011-12-29
申请号：US13168547
申请日：2011-06-24
CPC分类号： A61N1/36514 , A61B5/02133 , A61B5/026 , A61N1/08 , A61N1/36142 , A61N1/36578
摘要： Systems and methods to monitor cardiac mechanical vibrations using information indicative of lead motion are described. In an example, a system including an implantable medical device can include an excitation circuit configured to provide a non-tissue stimulating, non-therapeutic electrical excitation signal to a portion of an implantable lead. A receiver circuit can be configured to obtain information indicative of a mechanical vibration of the implantable lead due at least in part to one or more of an impact of at least a portion of the heart to the implantable lead, or friction contact between the implantable lead and cardiac tissue. The system can include a processor circuit configured to determine one or more of a lead mechanical status, or information indicative of valvular activity using the information indicative of the mechanical vibration of the implantable lead.
摘要翻译： 描述使用指示引导运动的信息来监测心脏机械振动的系统和方法。 在一个示例中，包括可植入医疗装置的系统可以包括被配置为向可植入引线的一部分提供非组织刺激的非治疗电激励信号的激励电路。 接收器电路可以被配置为获得指示可植入引线的机械振动的信息，其至少部分地由至少一部分心脏到可植入引线的冲击或可植入引线之间的摩擦接触 和心脏组织。 该系统可以包括处理器电路，其被配置为使用指示可植入引线的机械振动的信息来确定引导机械状态或指示瓣膜活动的信息中的一个或多个。
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公开(公告)号：US20110319779A1
公开(公告)日：2011-12-29
申请号：US13168481
申请日：2011-06-24
IPC分类号： A61B5/0452 , A61B5/02 , A61N1/365
CPC分类号： A61N1/36514 , A61B5/02133 , A61B5/026 , A61N1/08 , A61N1/36142 , A61N1/36578
摘要： Systems and methods for rhythm discrimination using the motion of an implantable lead are described. In an example, an implantable medical device can include a receiver circuit configured to be electrically coupled to an implantable lead and be configured to obtain information indicative of a movement of the implantable lead due at least in part to a motion of a heart. The device can include an arrhythmia detection circuit configured to determine an arrhythmia status using the information indicative of the movement of the implantable lead and an arrhythmia classification circuit configured to determine one or more of a location or a type of an arrhythmia, using the information indicative of the movement of the implantable lead, when the arrhythmia status indicates that an arrhythmia is occurring or has occurred.
摘要翻译： 描述使用可植入引线的运动进行节律辨别的系统和方法。 在一个示例中，可植入医疗设备可以包括被配置为电耦合到可植入引线的接收器电路，并且被配置为获得至少部分地基于心脏的运动而指示可植入引线的运动的信息。 该装置可以包括心律失常检测电路，其被配置为使用指示可植入引线的移动的信息来确定心律失常状态，以及心律失常分类电路，其被配置为使用所述信息指示来确定心律不齐的位置或类型中的一个或多个 当心律失常状态表示发生心律失常或发生心律失常时，可植入性铅的运动。
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公开(公告)号：US20100241113A1
公开(公告)日：2010-09-23
申请号：US12727580
申请日：2010-03-19
申请人： Frank Ingle
发明人： Frank Ingle
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262
摘要： In some implementations, a cryotherapy delivery system includes a cryotherapy catheter having a distal treatment component that delivers, during a cryotherapy procedure, cryotherapy to a treatment site inside a patient's body; a controller that controls the delivery of the cryotherapy during the cryotherapy procedure; and a sensor that measures values of a respiration parameter of the patient during the cryotherapy procedure, and provides measured values to the controller. The controller can determine, prior to delivery of cryotherapy, a baseline value for the respiration parameter; detect, during delivery of the cryotherapy, a change in the respiration parameter relative to the baseline value; and suspend delivery of the cryotherapy when the change exceeds a threshold.
摘要翻译： 在一些实施方式中，冷冻治疗递送系统包括具有远端治疗组件的冷冻治疗导管，其在冷冻治疗过程期间将冷冻治疗递送至患者体内的治疗部位; 控制器在冷冻治疗过程中控制冷冻治疗的传递; 以及传感器，其在冷冻治疗过程中测量患者的呼吸参数的值，并将测量值提供给控制器。 控制器可以在冷冻治疗之前确定呼吸参数的基准值; 在传递冷冻疗法期间，检测呼吸参数相对于基线值的变化; 并且当变化超过阈值时，暂停冷冻治疗。
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公开(公告)号：US07351211B2
公开(公告)日：2008-04-01
申请号：US11245625
申请日：2005-10-07
CPC分类号： A61B18/148 , A61B18/1477 , A61B90/39 , A61B2018/1407 , A61B2018/1425 , A61B2018/143 , A61B2018/1432 , A61B2018/144 , A61B2090/3908
摘要： A tissue separator assembly has an elongate tubular member and a tissue separator device located at a distal end of the elongate tubular member. An elongate coupler extends through the lumen of the elongate tubular member and has a distal coupler end. A tissue localization assembly has an elongate member and a localization device located at the distal end of the elongate member. The localization device may be movable from a first, radially-contracted state to a second, radially-expandable state. The distal coupler end of the elongate coupler and the proximal end of the elongate tubular member of the localization assembly are joinable to one another to permit docking of the tissue localization assembly to the tissue separator assembly. Methods of use of this device are also described.
摘要翻译： 组织分离器组件具有细长的管状构件和位于细长管状构件的远端处的组织分离器装置。 细长联接器延伸穿过细长管状构件的内腔并且具有远端联接器端部。 组织定位组件具有细长构件和位于细长构件的远端处的定位装置。 定位装置可以从第一径向收缩状态移动到第二径向可扩张状态。 细长联接器的远端联接器端和定位组件的细长管状构件的近端可彼此连接，以允许组织定位组件对接组织分离器组件。 还描述了该装置的使用方法。
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公开(公告)号：US6081749A
公开(公告)日：2000-06-27
申请号：US910371
申请日：1997-08-13
申请人： Frank Ingle , Garry Carter
发明人： Frank Ingle , Garry Carter
CPC分类号： A61B18/1485 , A61B18/1815 , A61B2017/00084 , A61B2017/003 , A61B2018/00011 , A61B2018/00023 , A61B2018/0016 , A61B2018/0022 , A61B2018/00517 , A61B2018/00523 , A61B2018/00553 , A61B2018/00791 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/1467 , A61B2018/1472 , A61B2090/3782 , A61B2218/002 , A61N7/02
摘要： The invention provides improved devices, methods, and systems for shrinking of collagenated tissues, particularly for treating urinary incontinence in a noninvasive manner by directing energy to a patient's own support tissues. This energy gently heats fascia and other collagenated support tissues, causing them to contract. The energy will preferably be applied between a pair of large plate electrodes having cooled flat electrode surfaces. Such cooled plate electrodes are capable of directing electrical energy through an intermediate tissue and into fascia while the cooled electrode surface prevents injury to the intermediate tissue. Ideally, the plate electrode comprises an electrode array including discrete electrode surface segments so that the current flux can be varied to selectively target the fascia.
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27.发明授权Cardiac mechanical vibration monitor using information indicative of lead motion 有权心脏机械振动监测器使用指示引导运动的信息公开(公告)号：US08532770B2
公开(公告)日：2013-09-10
申请号：US13168547
申请日：2011-06-24
IPC分类号： A61N1/365
CPC分类号： A61N1/36514 , A61B5/02133 , A61B5/026 , A61N1/08 , A61N1/36142 , A61N1/36578
摘要： Systems and methods to monitor cardiac mechanical vibrations using information indicative of lead motion are described. In an example, a system including an implantable medical device can include an excitation circuit configured to provide a non-tissue stimulating, non-therapeutic electrical excitation signal to a portion of an implantable lead. A receiver circuit can be configured to obtain information indicative of a mechanical vibration of the implantable lead due at least in part to one or more of an impact of at least a portion of the heart to the implantable lead, or friction contact between the implantable lead and cardiac tissue. The system can include a processor circuit configured to determine one or more of a lead mechanical status, or information indicative of valvular activity using the information indicative of the mechanical vibration of the implantable lead.
摘要翻译： 描述使用指示引导运动的信息来监测心脏机械振动的系统和方法。 在一个示例中，包括可植入医疗装置的系统可以包括被配置为向可植入引线的一部分提供非组织刺激的非治疗电激励信号的激励电路。 接收器电路可以被配置为获得指示可植入引线的机械振动的信息，其至少部分地由至少一部分心脏到可植入引线的冲击或可植入引线之间的摩擦接触 和心脏组织。 该系统可以包括处理器电路，其被配置为使用指示可植入引线的机械振动的信息来确定引导机械状态或指示瓣膜活动的信息中的一个或多个。
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公开(公告)号：US08128617B2
公开(公告)日：2012-03-06
申请号：US12127287
申请日：2008-05-27
申请人： Bob Bencini , Frank Ingle , Joe Koblish , Rebecca Tin , Jim Mazzone , Byron Chun , David Lawrence
发明人： Bob Bencini , Frank Ingle , Joe Koblish , Rebecca Tin , Jim Mazzone , Byron Chun , David Lawrence
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B5/0422 , A61B2018/00017 , A61B2018/00023 , A61B2018/0022 , A61B2018/00714 , A61B2018/00791 , A61B2018/00797 , A61B2018/0212 , A61B2018/0262
摘要： In some implementations, a method of ablating body tissue includes (a) locating an inflatable balloon portion of a cryotherapy balloon catheter at a treatment site internal to a patient's body, and inflating the inflatable balloon portion; (b) employing electrodes that are disposed on an expandable surface of the inflatable balloon portion to electrically characterize body tissue at the treatment site; (c) ablating the body tissue by supplying a cryotherapy agent to the inflatable balloon portion to cool the body tissue to a therapeutic temperature; (d) employing the electrodes to determine whether the ablating caused desired electrical changes in the body tissue; and (e) repeating (c) and (d) when it is determined that the ablating did not cause the desired electrical changes.
摘要翻译： 在一些实施方式中，一种消融身体组织的方法包括（a）将冷冻治疗气囊导管的可充气球囊部分定位在患者身体内部的治疗部位，并使可充气球囊部分膨胀; （b）使用设置在所述可膨胀气囊部分的可膨胀表面上的电极来电性地表征所述治疗部位的身体组织; （c）通过向所述可充气球囊部分供应冷冻治疗剂来将所述身体组织冷却至治疗温度来烧蚀所述身体组织; （d）使用电极来确定烧蚀是否引起人体组织中所需的电变化; 和（e）重复（c）和（d）当确定烧蚀没有引起所需的电气变化时。
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公开(公告)号：US20110257523A1
公开(公告)日：2011-10-20
申请号：US13086116
申请日：2011-04-13
CPC分类号： A61N7/022 , A61B8/0891 , A61B8/12 , A61B8/4488 , A61B18/0206 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2090/3784 , A61N2007/003 , A61N2007/0095
摘要： Acoustic energy is delivered to innervated vascular that contributes to renal sympathetic nerve activity, such as innervated tissue of the renal artery and abdominal aorta. Focused acoustic energy is delivered via an intravascular device of sufficient power to ablate innervated renal or aortal tissue. Focused acoustic energy may be delivered via an intravascular or extracorporeal device to image and locate target innervated renal or aortal tissue. Intravascular, extravascular, or transvascular focused ultrasound devices provide for high precision denervation of innervated vascular to terminate renal sympathetic nerve activity.
摘要翻译： 声能传递给有助于肾交感神经活动的神经支配的血管，如肾动脉和腹主动脉的神经支配组织。 聚焦的声能通过具有足够功率的血管内装置递送以消融支配的肾脏或主动脉组织。 聚焦的声能可以通过血管内或体外装置递送到图像并定位目标神经支配的肾或主动脉组织。 血管内，血管外或经血管聚焦的超声装置提供神经支配血管的高精度去神经支配以终止肾交感神经活动。
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公开(公告)号：US20110152857A1
公开(公告)日：2011-06-23
申请号：US12916502
申请日：2010-10-30
申请人： Frank Ingle
发明人： Frank Ingle
IPC分类号： A61B18/12
CPC分类号： A61B18/1206 , A61B18/1492 , A61B2018/00023 , A61B2018/00029 , A61B2018/00101 , A61B2018/00589 , A61B2018/00642 , A61B2018/00648 , A61B2018/00684 , A61B2018/00702 , A61B2018/00791 , A61B2018/00821 , A61B2018/00875 , A61B2090/065
摘要： Methods and apparatus in accordance with at least some of the present disclosure employ a measured heat transfer property to evaluate electrode/tissue contact. Methods and apparatus in accordance with at least some of the present disclosure employ the relationship between impedance measurements and sub-surface temperature to control power.
摘要翻译： 根据本公开的至少一些方法和装置采用测量的传热性能来评估电极/组织接触。 根据本公开的至少一些的方法和装置采用阻抗测量和次表面温度之间的关系来控制功率。
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