利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

30 条记录 (耗时 0.028 秒)

    POLYMERIC, DEGRADABLE DRUG-ELUTING STENTS AND COATINGS
    21.
    发明申请
    POLYMERIC, DEGRADABLE DRUG-ELUTING STENTS AND COATINGS 有权
    聚合，可降解药水和涂层

    公开(公告)号：US20090093872A1

    公开(公告)日：2009-04-09

    申请号：US12251173

    申请日：2008-10-14

    申请人： Klaus-Peter Schmitz ,  Detlef Behrend ,  Katrin Sternberg ,  Niels Grabow ,  David P. Martin ,  Simon F. Williams

    发明人： Klaus-Peter Schmitz ,  Detlef Behrend ,  Katrin Sternberg ,  Niels Grabow ,  David P. Martin ,  Simon F. Williams

    IPC分类号： A61L27/54 ,  A61F2/82 ,  A61F2/84

    CPC分类号： A61L31/18 ,  A61F2/82 ,  A61F2210/0004 ,  A61F2250/0067 ,  A61L31/10 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/606 ,  C08L67/04

    摘要： Absorbable stents and absorbable stent coatings have been developed with improved properties. These devices preferably comprise biocompatible copolymers or homopolymers of 4-hydroxybutyrate, and optionally polylactic acid and other absorbable polymers and additives. Compositions of these materials can be used to make absorbable stents that provide advantageous radial strengths, resistance to recoil and creep, can be plastically expanded on a balloon catheter, and can be deployed rapidly in vivo. Stent coatings derived from these materials provide biocompatible, uniform coatings that are ductile, and can be expanded without the coating cracking and/or delaminating and can be used as a coating matrix for drug incorporation.

    摘要翻译： 可吸收支架和可吸收支架涂层已经开发出具有改进的性能。 这些装置优选包括生物相容性共聚物或4-羟基丁酸酯的均聚物，以及任选的聚乳酸和其它可吸收的聚合物和添加剂。 这些材料的组合物可用于制造提供有利的径向强度，抵抗反冲和蠕变的可吸收支架，可以在球囊导管上塑性膨胀，并且可以在体内迅速部署。 衍生自这些材料的支架涂层提供生物相容性均匀的延展性涂层，并且可以在没有涂层开裂和/或分层的情况下扩展，并且可以用作药物掺入的涂层基质。

    POLYURETHANE UREA FOR STENT COATINGS
    22.
    发明申请
    POLYURETHANE UREA FOR STENT COATINGS 审中-公开
    用于固体涂料的聚氨酯尿素

    公开(公告)号：US20120263778A1

    公开(公告)日：2012-10-18

    申请号：US13516440

    申请日：2010-12-10

    申请人： Jürgen Köcher ,  Christian Wamprecht ,  Henning Rohm ,  Klaus-Peter Schmitz ,  Katrin Sternberg

    发明人： Jürgen Köcher ,  Christian Wamprecht ,  Henning Rohm ,  Klaus-Peter Schmitz ,  Katrin Sternberg

    IPC分类号： C08G18/28 ,  A61P9/00 ,  A61K9/00 ,  A61F2/82 ,  B05D1/36 ,  A61K47/34

    CPC分类号： C08G18/44 ,  A61L29/085 ,  A61L31/10 ,  C08G18/0823 ,  C08G18/12 ,  C09D175/04 ,  C09D175/06 ,  C08G18/3234 ,  C08L75/04

    摘要： The invention relates to a polyurethane urea comprising structural units of formula (I), not terminated by at least one copolymer unit of polyethylene oxide and polypropylene oxide, and that can particularly be used for producing stent coatings. The invention further relates to a substrate having a base coating made of a polyurethane urea according to the invention. The invention further relates to a coating structure comprising at least one layer comprising active substances and made of a polyurethane urea according to the invention, and at least one layer free of active substances, made of a polyurethane urea according to the invention. The invention finally relates to a method for coating a substrate, wherein at least one layer made of a polyurethane urea according to the invention is applied to the substrate.

    摘要翻译： 本发明涉及包含式（I）结构单元的聚氨酯脲，其不被聚环氧乙烷和聚环氧丙烷的至少一种共聚物单元封端，并且特别可用于制备支架涂层。 本发明还涉及一种具有根据本发明的由聚氨酯脲制成的基底涂层的基底。 本发明还涉及一种涂层结构，其包括至少一层包含活性物质并由根据本发明的聚氨酯脲制成的层和至少一层不含活性物质的层，该层由本发明的聚氨酯脲制成。 本发明最终涉及用于涂布基材的方法，其中根据本发明的由聚氨酯脲制成的至少一层施加到基材上。

    Stapedius muscle electrode
    25.
    发明授权
    Stapedius muscle electrode 有权
    脚趾肌电极

    公开(公告)号：US08280480B2

    公开(公告)日：2012-10-02

    申请号：US12527263

    申请日：2008-02-19

    申请人： Hans Wilhelm Pau ,  Detlef Behrend ,  Wolfram Schmidt ,  Klaus-Peter Schmitz

    发明人： Hans Wilhelm Pau ,  Detlef Behrend ,  Wolfram Schmidt ,  Klaus-Peter Schmitz

    IPC分类号： A61B5/04

    CPC分类号： A61B5/0492 ,  A61B5/6817 ,  A61N1/0541

    摘要： The invention relates to a stapedius muscle electrode array for detecting the action elements generated when a human stapedius muscle is contracted. Said array comprises an electrode (2, 2′, 2″) that is adapted for bipolar discharge and is to be attached to a human stapedius muscle. The electrode has two flexible, elastic, electrically conducting elongate elements (2a, 2b), each of which has a distal (4a, 4b) and a proximal end (17a, 17b) and is helically preshaped along at least some of the length thereof to the distal end (4a, 4b) thereof in such a way that the distal end (4a, 4b) and a section of the respective elongate element (2a, 2b) which adjoins the distal end (4a, 4b) can be placed at least in part around the tendon (7) extending between the stapedius muscle and the stapes while the helical part can be guided along the tendon (7), can be moved in the direction of the stapedius muscle, and can be at least partly twisted into and/or slid onto the region of the muscle belly (6) adjoining the tendon (7). The two elongate elements (2a, 2b) are electrically insulated from one another, and the helical parts (3) thereof are intertwined in such a way as to run around a common centerline (11), allowing the helical parts (3) to be jointly placed around the tendon (7), be guided along the tendon (7), and be brought in contact with the stapedius muscle.

    摘要翻译： 本发明涉及一种用于检测当人类镫骨肌收缩时产生的动作元件的镫骨肌电极阵列。 所述阵列包括适于双极放电并且连接到人类镫骨肌的电极（2,2'，2“）。 电极具有两个柔性的，弹性的，导电的细长元件（2a，2b），每个元件具有远端（4a，4b）和近端（17a，17b），并且沿其长度的至少一部分螺旋状地预成形 到远端（4a，4b），使远端（4a，4b）和与远端（4a，4b）相邻的相应的细长元件（2a，2b）的一部分可以放置在 至少部分地围绕在镫骨和镫骨之间延伸的腱（7），而螺旋部分可以沿着腱（7）被引导，可以沿着镫骨肌的方向移动，并且可以至少部分地扭曲成 和/或滑动到与肌腱（7）相邻的肌肉腹部（6）的区域上。 两个细长元件（2a，2b）彼此电绝缘，并且其螺旋部分（3）以相互缠绕的方式相互缠绕，以便围绕共同的中心线（11）延伸，从而允许螺旋部分（3）为 围绕腱（7）共同放置，沿腱（7）引导，并与镫骨肌接触。

    Stapedius Muscle Electrode
    26.
    发明申请
    Stapedius Muscle Electrode 有权
    Stapedius肌肉电极

    公开(公告)号：US20100145177A1

    公开(公告)日：2010-06-10

    申请号：US12527263

    申请日：2008-02-19

    申请人： Hans Wilhelm Pau ,  Detlef Behrend ,  Wolfram Schmidt ,  Klaus-Peter Schmitz

    发明人： Hans Wilhelm Pau ,  Detlef Behrend ,  Wolfram Schmidt ,  Klaus-Peter Schmitz

    IPC分类号： A61B5/0492

    CPC分类号： A61B5/0492 ,  A61B5/6817 ,  A61N1/0541

    摘要： The invention relates to a stapedius muscle electrode array for detecting the action elements generated when a human stapedius muscle is contracted. Said array comprises an electrode (2, 2′, 2″) that is adapted for bipolar discharge and is to be attached to a human stapedius muscle. The electrode has two flexible, elastic, electrically conducting elongate elements (2a, 2b), each of which has a distal (4a, 4b) and a proximal end (17a, 17b) and is helically preshaped along at least some of the length thereof to the distal end (4a, 4b) thereof in such a way that the distal end (4a, 4b) and a section of the respective elongate element (2a, 2b) which adjoins the distal end (4a, 4b) can be placed at least in part around the tendon (7) extending between the stapedius muscle and the stapes while the helical part can be guided along the tendon (7), can be moved in the direction of the stapedius muscle, and can be at least partly twisted into and/or slid onto the region of the muscle belly (6) adjoining the tendon (7). The two elongate elements (2a, 2b) are electrically insulated from one another, and the helical parts (3) thereof are intertwined in such a way as to run around a common centerline (11), allowing the helical parts (3) to be jointly placed around the tendon (7), be guided along the tendon (7), and be brought in contact with the stapedius muscle.

    摘要翻译： 本发明涉及一种用于检测当人类镫骨肌收缩时产生的动作元件的镫骨肌电极阵列。 所述阵列包括适于双极放电并且连接到人类镫骨肌的电极（2,2'，2“）。 电极具有两个柔性的，弹性的，导电的细长元件（2a，2b），每个元件具有远端（4a，4b）和近端（17a，17b），并且沿其长度的至少一部分螺旋状地预成形 到远端（4a，4b），使远端（4a，4b）和与远端（4a，4b）相邻的相应的细长元件（2a，2b）的一部分可以放置在 至少部分地围绕在镫骨和镫骨之间延伸的腱（7），而螺旋部分可以沿着腱（7）被引导，可以沿着镫骨肌的方向移动，并且可以至少部分地扭曲成 和/或滑动到与肌腱（7）相邻的肌肉腹部（6）的区域上。 两个细长元件（2a，2b）彼此电绝缘，并且其螺旋部分（3）以相互缠绕的方式相互缠绕，以便围绕共同的中心线（11）延伸，从而允许螺旋部分（3）为 围绕腱（7）共同放置，沿腱（7）引导，并与镫骨肌接触。

    Isoelastic Endodontic Pin
    27.
    发明申请
    Isoelastic Endodontic Pin 审中-公开
    等弹性牙髓针

    公开(公告)号：US20090047635A1

    公开(公告)日：2009-02-19

    申请号：US11913247

    申请日：2006-04-26

    申请人： Detlef Behrend ,  Heinrich Von Schwanewede ,  Klaus-Peter Schmitz

    发明人： Detlef Behrend ,  Heinrich Von Schwanewede ,  Klaus-Peter Schmitz

    IPC分类号： A61C13/30

    CPC分类号： A61C13/30

    摘要： An isoelastic endodontic pin for the long-term endodontic restoration of teeth is based on a single-piece, fibre-reinforced plastic base body having deformation zones and at least one zone designed in such a way that it possesses reduced flexural and torsional strength; displacement elements, preferably channels, for a fastening material are located outside these zones.

    摘要翻译： 用于牙齿长期牙髓修复的等弹性牙髓根据具有变形区域和至少一个设计成具有降低的弯曲和扭转强度的方式设计的单件式纤维增强塑料基体， 用于紧固材料的位移元件，优选通道位于这些区域之外。

    Method and device for crimping a stent
    28.
    发明授权
    Method and device for crimping a stent 失效
    用于压接支架的方法和装置

    公开(公告)号：US06726713B2

    公开(公告)日：2004-04-27

    申请号：US09923808

    申请日：2001-08-07

    申请人： Max Schaldach ,  Detlef Behrend ,  Klaus-Peter Schmitz ,  Heinz Mueller ,  Daniel Lootz ,  Dietmar Esperschidt

    发明人： Max Schaldach ,  Detlef Behrend ,  Klaus-Peter Schmitz ,  Heinz Mueller ,  Daniel Lootz ,  Dietmar Esperschidt

    IPC分类号： A61F206

    CPC分类号： A61F2/958 ,  A61F2002/9522

    摘要： The invention concerns a method and a device for crimping a stent onto a balloon of a balloon catheter. The stent is arranged on the balloon so that an outside surface of the balloon and an inside surface of the stent contact each other to form a combination of balloon and stent. The combination is compressed to crimp the stent onto the balloon. The invention is distinguished in that the combination is compressed to varying degrees along the longitudinal axis of the combination.

    摘要翻译： 本发明涉及一种用于将支架卷曲到球囊导管的球囊上的方法和装置。 支架布置在气囊上，使得球囊的外表面和支架的内表面彼此接触以形成球囊和支架的组合。 将组合物压缩以将支架卷曲到气球上。 本发明的区别在于，组合沿着组合的纵向轴线被不同程度地压缩。

    Method for the manufacture of intraluminal stents of bioresorbable polymeric material
    29.
    发明授权
    Method for the manufacture of intraluminal stents of bioresorbable polymeric material 失效
    生物可再吸收聚合材料管腔内支架的制造方法

    公开(公告)号：US5935506A

    公开(公告)日：1999-08-10

    申请号：US733172

    申请日：1996-10-17

    申请人： Klaus-Peter Schmitz ,  Detlef Behrend

    发明人： Klaus-Peter Schmitz ,  Detlef Behrend

    IPC分类号： A61F2/82 ,  A61L31/06 ,  B29C41/08 ,  B29C41/14 ,  B29C41/22 ,  B29C33/40 ,  B28B1/38 ,  A61F2/06

    CPC分类号： B29C41/22 ,  A61L31/06 ,  B23K26/402 ,  B29C41/08 ,  B29C41/14 ,  A61F2/82 ,  B23K2203/42 ,  Y10S623/90 ,  Y10S623/901

    摘要： A method for the manufacture of intravascular stents of bioresorbable material comprises the following steps:preparing a viscous solution of poly-.beta.-hydroxybutanoic acid as a bioresorbable polymeric material in a solvent,successively coating a male mold core with layers of the polymer solution in several steps by precipitation of the polymeric material by the solvent being evaporated and by the layer previously precipitated being dissolved at least partially for a homogeneous stent blank to build up,drawing the stent blank off the male mold core, andsubsequently treating the stent blank to finish the shaping of the stent.

    摘要翻译： 用于制造生物可再吸收材料的血管内支架的方法包括以下步骤：在溶剂中制备聚-β-羟基丁酸作为生物可再吸收的聚合物材料的粘性溶液，依次用多层聚合物溶液涂覆阳模芯 通过被蒸发的溶剂沉淀聚合物材料并通过预先沉淀的层至少部分地溶解以使均匀的支架坯料积聚，从而将支架坯料拉出阳模芯，然后将支架坯料处理完成 支架的成型。

    Bearing structure
    30.
    发明授权
    Bearing structure 失效
    轴承结构

    公开(公告)号：US07727272B2

    公开(公告)日：2010-06-01

    申请号：US10535081

    申请日：2003-11-12

    申请人： Martin Schlun ,  Heiner Martin ,  Klaus-Peter Schmitz

    发明人： Martin Schlun ,  Heiner Martin ,  Klaus-Peter Schmitz

    IPC分类号： A61F2/06

    CPC分类号： A61F2/91 ,  A61F2/915 ,  A61F2002/91541 ,  A61F2002/9155

    摘要： A one-piece expandable flat bearing structure formed by at least partially elastically deformable struts which are separated from each other by openings in the bearing structure. The bearing structure can assume at least one compressed condition and at least one expanded condition and has at least one expansion direction. The bearing structure has anchor regions, from which spring struts, which are elastically resilient with respect to the anchor regions, extend to a resiliently deflectable end of the spring struts, a hinge strut adjoining said end. The spring struts and the hinge struts are of such a configuration and arrangement that both the compressed condition of the bearing structure and also the expanded condition of the bearing structure is stabilized by a spring action emanating from the spring struts.

    摘要翻译： 一体式可膨胀平板轴承结构，由至少部分弹性变形的支柱形成，它们通过轴承结构中的开口彼此分开。 轴承结构可以呈现至少一个压缩状态和至少一个膨胀状态，并具有至少一个膨胀方向。 轴承结构具有锚定区域，相对于锚固区域弹性支撑弹簧支撑件从该弹性支柱延伸到弹簧支柱的可弹性偏转的端部，与所述端部相邻的铰链支柱。 弹簧支柱和铰链支柱具有这样的构造和布置，使得轴承结构的压缩状态以及轴承结构的膨胀状态都可以通过从弹簧支柱产生的弹簧作用来稳定。