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21.发明授权公开(公告)号：US08372225B2
公开(公告)日：2013-02-12
申请号：US12093817
申请日：2006-11-17
申请人： Thomas Bailey , Ronnie Benditt , Nigel Brewerton , Steven D. Finkelmeier , Robert Glinecke , Luigi Martini , Paul Simmons
发明人： Thomas Bailey , Ronnie Benditt , Nigel Brewerton , Steven D. Finkelmeier , Robert Glinecke , Luigi Martini , Paul Simmons
IPC分类号： B32B41/00
CPC分类号： B65B1/04 , A61J3/06 , A61J3/10 , Y10T156/10
摘要： A method and apparatus for assembling a plurality of independently formed solid components is provided thereby forming a single delivery vehicle for a pharmaceutical or pharmaceutical-like product. The solid components can be held and fed to the apparatus via a plurality of magazines. Pusher rods and the like can be used for positioning each of the solid components. Where the components are connected via a bonding liquid, a sprayer is provided and compression pins or the like press the components with the bonding liquid together to form the final product. A rivet or other connection structure can also be used and driven through holes in each of the solid components to form the final product.
摘要翻译： 提供了用于组装多个独立形成的固体组分的方法和装置，从而形成用于药物或药物样产品的单一递送载体。 可以通过多个杂志将固体成分保持并供给至装置。 推杆等可用于定位每个固体组分。 在通过粘合液体连接部件的情况下，设置喷雾器，压接销等将粘合液体的部件压在一起形成最终产品。 铆钉或其他连接结构也可以通过每个固体组分中的孔使用和驱动以形成最终产品。
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22.发明申请公开(公告)号：US20080306622A1
公开(公告)日：2008-12-11
申请号：US12093817
申请日：2006-11-17
申请人： Thomas Bailey , Ronnie Benditt , Nigel Brewerton , Steven D. Finkelmeier , Robert Glinecke , Luigi Martini , Paul Simmons
发明人： Thomas Bailey , Ronnie Benditt , Nigel Brewerton , Steven D. Finkelmeier , Robert Glinecke , Luigi Martini , Paul Simmons
IPC分类号： G06F19/00
CPC分类号： B65B1/04 , A61J3/06 , A61J3/10 , Y10T156/10
摘要： A method and apparatus for assembling a plurality of independently formed solid components is provided thereby forming a single delivery vehicle for a pharmaceutical or pharmaceutical-like product. The solid components can be held and fed to the apparatus via a plurality of magazines. Pusher rods and the like can be used for positioning each of the solid components. Where the components are connected via a bonding liquid, a sprayer is provided and compression pins or the like press the components with the bonding liquid together to form the final product. A rivet or other connection structure can also be used and driven through holes in each of the solid components to form the final product.
摘要翻译： 提供了用于组装多个独立形成的固体组分的方法和装置，从而形成用于药物或药物样产品的单一递送载体。 可以通过多个杂志将固体成分保持并供给至装置。 推杆等可用于定位每个固体组分。 在通过粘合液体连接部件的情况下，设置喷雾器，压接销等将粘合液体的部件压在一起形成最终产品。 铆钉或其他连接结构也可以通过每个固体组分中的孔使用和驱动以形成最终产品。
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公开(公告)号：US07122178B1
公开(公告)日：2006-10-17
申请号：US10030411
申请日：2000-07-07
申请人： Paul Simmons , Andrew Zannettino , Stan Gronthos
发明人： Paul Simmons , Andrew Zannettino , Stan Gronthos
CPC分类号： C12N5/0663 , A61K2035/124 , C12N2500/42 , C12N2501/39
摘要： A method of enriching mesenchymal precursor sells including the step of enriching for cells based on at least two markers. The markers may be either i) the presence of markers specific for mesenchymal precursor cells, ii) the absence of markers specific for differentiated mesenchymal cells, or iii) expression levels of markers specific for mesenchymal precursor cells. The method may include a first solid phase sorting step utilizing MACS recognizing expression of the antigen to the STRO-1 Mab, followed by a second sorting step utilizing two color FACS to screen for the presence of high level STRO-1 antigen expression as well as the expression of VCAM-1.
摘要翻译： 富含间充质前体的方法包括基于至少两种标记物富集细胞的步骤。 标记可能是i）对间质前体细胞特异性标志物的存在，ii）不存在对分化的间充质细胞特异性的标记，或iii）对间充质前体细胞特异的标志物的表达水平。 该方法可以包括利用识别STRO-1 Mab抗原表达的MACS的第一固相分选步骤，随后使用两色FACS来筛选高水平STRO-1抗原表达的存在的第二分选步骤，以及 VCAM-1的表达。
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公开(公告)号：US20060008452A1
公开(公告)日：2006-01-12
申请号：US11178920
申请日：2005-07-11
申请人： Paul Simmons , Andrew Zannettino , Stan Gronthos
发明人： Paul Simmons , Andrew Zannettino , Stan Gronthos
CPC分类号： C12N5/0663 , A61K2035/124 , C12N2500/42 , C12N2501/39
摘要： A method of enriching mesenchymal precursor sells including the step of enriching for cells based on at least two markers. The markers may be either i) the presence of markers specific for mesenchymal precursor cells, ii) the absence of markers specific for differentiated mesenchymal cells, or iii) expression levels of markers specific for mesenchymal precursor cells. The method may include a first solid phase sorting step utilizing MACS recognizing expression of the antigen to the STRO-1 Mab, followed by a second sorting step utilizing two color FACS to screen for the presence of high level STRO-1 antigen expression as well as the expression of VCAM-1.
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公开(公告)号：US5992880A
公开(公告)日：1999-11-30
申请号：US993959
申请日：1997-12-18
申请人： Mark Anthony Cuddihy , J B Drummond , Matt Alan Niesluchowski , Richard Michael Ross , Paul Simmons
发明人： Mark Anthony Cuddihy , J B Drummond , Matt Alan Niesluchowski , Richard Michael Ross , Paul Simmons
IPC分类号： B60R21/01 , B60R21/015 , B60R21/32
CPC分类号： B60R21/01566 , B60R21/01564
摘要： An airbag deactivation system for the airbags mounted in a motor vehicle. The system provides a switch and circuitry to allow for selective deactivation of driver and/or passenger airbags in a motor vehicle via a conventional ignition key inserted into a key cylinder. The switch includes interchangeable key cylinders to allow for limited selective deactivation and a key stop to limit the amount of insertion of the ignition key into the key cylinder. LED's emit light from the deactivation module when indicating a deactivation condition, which is viewable by both a driver and a front seat passenger. Alternatively, LED's are mounted in a remote indicator assembly, separate from the deactivation module, to povide improved visual indication to the driver and font seat passenger of the state of airbag deactivation.
摘要翻译： 一种用于安装在机动车辆中的安全气囊的安全气囊去激活系统。 该系统提供开关和电路，以允许通过插入钥匙筒中的常规点火钥匙来选择性地停用机动车辆中的驾驶员和/或乘客安全气囊。 开关包括可互换的钥匙筒，以允许有限的选择性停用和钥匙停止以将点火钥匙的插入量限制在钥匙筒中。 当指示停用状态时，LED从停用模块发出，该停用条件可由驾驶员和前排乘客查看。 或者，LED被安装在与停用模块分离的远程指示器组件中，以向安全气囊停用状态的驾驶员和字体座椅乘客提供改进的视觉指示。
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公开(公告)号：US5938234A
公开(公告)日：1999-08-17
申请号：US993961
申请日：1997-12-18
申请人： Mark Anthony Cuddihy , Thomas F. Hrynik , Matt Alan Niesluchowski , Richard Michael Ross , Paul Simmons , J B Drummond
发明人： Mark Anthony Cuddihy , Thomas F. Hrynik , Matt Alan Niesluchowski , Richard Michael Ross , Paul Simmons , J B Drummond
IPC分类号： B60R21/01 , B60R21/015 , B60R21/32
CPC分类号： B60R21/01566 , B60R21/01564
摘要： An airbag deactivation system for the airbags mounted in a motor vehicle. The system provides a switch and circuitry to allow for selective deactivation of driver and/or passenger airbags in a motor vehicle via a conventional ignition key inserted into a key cylinder. The switch includes interchangeable key cylinders to allow for limited selective deactivation and a key stop to limit the amount of insertion of the ignition key into the key cylinder. LED's emit light from the deactivation module when indicating a deactivation condition, which is viewable by both a driver and a front seat passenger. Alternatively, LED's are mounted in a remote indicator assembly, separate from the deactivation module, to provide improved visual indication to the driver and front seat passenger of the state of airbag deactivation.
摘要翻译： 一种用于安装在机动车辆中的安全气囊的安全气囊去激活系统。 该系统提供开关和电路，以允许通过插入钥匙筒中的常规点火钥匙来选择性地停用机动车辆中的驾驶员和/或乘客安全气囊。 开关包括可互换的钥匙筒，以允许有限的选择性停用和钥匙停止以将点火钥匙的插入量限制在钥匙筒中。 当指示停用状态时，LED从停用模块发出，该停用条件可由驾驶员和前排乘客查看。 或者，LED被安装在与停用模块分离的远程指示器组件中，以向驾驶员和前座乘客提供改进的对安全气囊停用状态的视觉指示。
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公开(公告)号：US5915725A
公开(公告)日：1999-06-29
申请号：US993960
申请日：1997-12-18
申请人： Mark Anthony Cuddihy , J B Drummond , Thomas F. Hrynik , Matt Alan Niesluchowski , Richard Michael Ross , Paul Simmons
发明人： Mark Anthony Cuddihy , J B Drummond , Thomas F. Hrynik , Matt Alan Niesluchowski , Richard Michael Ross , Paul Simmons
IPC分类号： B60R21/01 , B60R21/015 , B60R21/32
CPC分类号： B60R21/01566 , B60R21/01564 , Y10T70/7684
摘要： An airbag deactivation system for the airbags mounted in a motor vehicle. The system provides a switch and circuitry to allow for selective deactivation of driver and/or passenger airbags in a motor vehicle via a conventional ignition key inserted into a key cylinder. The switch includes interchangeable key cylinders to allow for limited selective deactivation and a key stop to limit the amount of insertion of the ignition key into the key cylinder. LED's emit light from the deactivation module when indicating a deactivation condition, which is viewable by both a driver and a front seat passenger. Alternatively, LED's are mounted in a remote indicator assembly, separate from the deactivation module, to provide improved visual indication to the driver and front seat passenger of the state of airbag deactivation
摘要翻译： 一种用于安装在机动车辆中的安全气囊的安全气囊去激活系统。 该系统提供开关和电路，以允许通过插入钥匙筒中的常规点火钥匙来选择性地停用机动车辆中的驾驶员和/或乘客安全气囊。 开关包括可互换的钥匙筒，以允许有限的选择性停用和钥匙停止以将点火钥匙的插入量限制在钥匙筒中。 当指示停用状态时，LED从停用模块发出，该停用条件可由驾驶员和前排乘客查看。 或者，LED被安装在与停用模块分离的远程指示器组件中，以向驾驶员和前排乘客提供改进的视觉指示，以使安全气囊失活状态
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公开(公告)号：US5544914A
公开(公告)日：1996-08-13
申请号：US456275
申请日：1994-12-27
IPC分类号： B60R21/16 , B60R21/01 , B60R21/015 , B60R21/32
CPC分类号： B60R21/01564 , B60R21/0173
摘要： A control circuit (46) for an air bag disabling system (16,22) includes a resistive test load (66) arranged in parallel with the resistive elements of the air bag (48) and in some embodiments includes a fuse (64) in series with the resistive test load (66), the resistive test load providing for the operation of the vehicle air bag system independent of the disabling effected by the disabling system and the fuse providing indication of operation of the air bag disabling system.
摘要翻译： 用于气囊禁用系统（16,22）的控制电路（46）包括与气囊（48）的电阻元件平行设置的电阻测试负载（66），并且在一些实施例中包括一个熔断器 系列具有电阻测试负载（66），电阻测试负载提供了汽车安全气囊系统的运行，独立于禁用系统进行的禁用和保险丝提供气囊禁用系统的操作指示。
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公开(公告)号：US08538672B2
公开(公告)日：2013-09-17
申请号：US11533941
申请日：2006-09-21
CPC分类号： B60R21/0136 , B60R2021/0006 , G08G1/166
摘要： A collision sensing system for a vehicle (10) includes a two-dimensional coil sensor (14) that is attached to a vehicle structure (19) A controller (20) is in communication with the two-dimensional coil sensor (14) and detects a collision event in response to movement of the vehicle structure (19) relative to a conductive member (98) of the vehicle (10). A collision detection and safety countermeasure system (12) for a vehicle (10) includes a coil sensor (14) that is adhered to a vehicle structure (19). A controller (20) is in communication with the coil sensor (14) and generates a countermeasure signal in response to movement by the vehicle structure (19) relative to a conductive member (98) of the vehicle (10).
摘要翻译： 一种用于车辆的碰撞感测系统（10）包括附接到车辆结构（19）的二维线圈传感器（14）。控制器（20）与二维线圈传感器（14）连通并检测 响应于车辆结构（19）相对于车辆（10）的导电构件（98）的移动的碰撞事件。 用于车辆（10）的碰撞检测和安全对策系统（12）包括粘附到车辆结构（19）上的线圈传感器（14）。 控制器（20）与线圈传感器（14）连通，响应于车辆结构（19）相对于车辆（10）的导电部件（98）的移动而产生对策信号。
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30.发明授权公开(公告)号：US07771334B2
公开(公告)日：2010-08-10
申请号：US11601023
申请日：2006-11-17
申请人： Thomas Bailey , Ronnie Benditt , Nigel Brewerton , Steven D. Finkelmeier , Robert Glinecke , Luigi Martini , Paul Simmons
发明人： Thomas Bailey , Ronnie Benditt , Nigel Brewerton , Steven D. Finkelmeier , Robert Glinecke , Luigi Martini , Paul Simmons
IPC分类号： B31B1/60
CPC分类号： B65B1/04 , A61J3/06 , A61J3/10 , Y10T156/10
摘要： A method and apparatus for assembling a plurality of independently formed solid components is provided thereby forming a single delivery vehicle for a pharmaceutical or pharmaceutical-like product. The solid components can be held and fed to the apparatus via a plurality of magazines. Pusher rods and the like can be used for positioning each of the solid components. Where the components are connected via a bonding liquid, a sprayer is provided and compression pins or the like press the components with the bonding liquid together to form the final product. A rivet or other connection structure can also be used and driven through holes in each of the solid components to form the final product.
摘要翻译： 提供了用于组装多个独立形成的固体组分的方法和装置，从而形成用于药物或药物样产品的单一递送载体。 可以通过多个杂志将固体成分保持并供给至装置。 推杆等可用于定位每个固体组分。 在通过粘合液体连接部件的情况下，设置喷雾器，压接销等将粘合液体的部件压在一起形成最终产品。 铆钉或其他连接结构也可以通过每个固体组分中的孔使用和驱动以形成最终产品。
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