公开(公告)号：US10399079B2

公开(公告)日：2019-09-03

申请号：US15546735

申请日：2015-01-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Nicholas McGuinness ,  Chantelle Domingue ,  Manish Giri ,  Jeremy Sells

IPC: B01L3/00 ,  G01N27/07 ,  G01N33/487

Abstract: A microfluidic diagnostic device may comprise a fluid inlet to receive a fluid from a fluidic slot, a main microfluidic channel fluidly coupled to the fluid inlet, and a main microfluidic pump interposed between the fluid inlet and the main microfluidic channel to continuously circulate a fluid through the fluidic slot, fluid inlet, and main microfluidic channel wherein the width of the fluid inlet is different from the width of the main microfluidic channel. A diagnostic device, comprising a fluidic slot, a fluid inlet fluidly coupled to the fluidic slot, a main channel fluidly coupled to the fluid inlet, and an inlet pump interposed between the fluid inlet and channel wherein the cross-sectional area of the fluid inlet is relatively larger at least one point than the cross-sectional area of the channel.

公开(公告)号：US20180321263A1

公开(公告)日：2018-11-08

申请号：US15749006

申请日：2016-03-07

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Rachel M. White ,  Manish Giri ,  Chantelle Domingue ,  Joshua M. Yu ,  Matthew David Smith ,  Sait M A Shameed

IPC: G01N33/86 ,  B01L3/00

CPC classification number: G01N33/86 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2300/0645 ,  B01L2300/0663 ,  B01L2400/0406 ,  B01L2400/0442 ,  B01L2400/0487 ,  G01N33/49 ,  G01N33/6893

Abstract: Examples herein provide a device. The device includes a testing cassette including: a microfluidic channel connecting an input port at a first end to at least one sensor area at a second end, the channel is to allow a blood sample to flow from the input port to the at least one sensor area; at least two electrodes; and a micro-fabricated integrated sensor, wherein when an electrical potential difference is applied over the blood sample, the sensor is to measure, over a duration of time, an electrical signal passing through the blood sample as the blood sample flows from the input port to the at least one sensor area and begin to coagulate, thereby obtaining a measurement function as a function of time. The device includes a processor to correlate the measurement function to a characteristic of the blood sample.

公开(公告)号：US20180214867A1

公开(公告)日：2018-08-02

申请号：US15748535

申请日：2016-01-29

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Matthew David Smith ,  Manish Giri ,  Chantelle Domingue

IPC: B01L3/00

CPC classification number: B01L3/50273 ,  B01L2300/0627 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2400/0442 ,  C12M23/16 ,  G11C19/28 ,  G16H40/63 ,  G16H50/20

Abstract: Provided herein are a system and method for using a microfluidics device. The system includes: a plurality of pumps and a plurality of sensors; a first communication line to select a pump from the plurality of pumps and select a sensor from the plurality of sensors; a second communication line selectively connected to the selected pump; and a third communication line selectively connected to the selected sensor.