-
公开(公告)号:US11628251B2
公开(公告)日:2023-04-18
申请号:US16586440
申请日:2019-09-27
Applicant: INSULET CORPORATION
Inventor: Jason O'Connor , Joon Bok Lee , Trang Ly , Todd Vienneau , Yibin Zheng , Ashutosh Zade
Abstract: A wearable drug delivery device, techniques, and computer-readable media that provide an application that implements a diabetes treatment plan for a user are described. The drug delivery device may include a controller operable to direct operation of the wearable drug delivery device. The controller may provide a selectable activity mode of operation for the user. Operation of the drug delivery device in the activity mode of operation may reduce a likelihood of hypoglycemia during times of increased insulin sensitivity for the user and may reduce a likelihood of hyperglycemia during times of increased insulin requirements for the user. The activity mode of operation may be manually activated by the user or may be activated automatically by the controller. The controller may automatically activate the activity mode of operation based on a detected activity level of the user and/or a detected location of the user.
-
公开(公告)号:US11551802B2
公开(公告)日:2023-01-10
申请号:US16787223
申请日:2020-02-11
Applicant: INSULET CORPORATION
Inventor: David Nazzaro , Steven Cardinali , Nicholas Conte , Daniel Allis , Jason O'Connor , Joon Bok Lee , Ashutosh Zade , Timothy Henning , Thomas Metzmaker , Ian McLaughlin
Abstract: Disclosed are examples of a device, a system, methods and computer-readable medium products operable to implement functionality to determine and respond to a purpose of a meal. An algorithm or application may receive data that may include data related to a meal purpose from data sources and determine whether any of the data received from the plurality of data sources was received from a direct data source or an indirect data source. The data may be evaluated to determine a purpose of the meal. Based on the results of the evaluation, instructions may be generated to provide an appropriate response based on the determined purpose of the meal. The generated instructions to provide the appropriate response based on the determined purpose of the meal may be output.
-
公开(公告)号:US11547800B2
公开(公告)日:2023-01-10
申请号:US16789051
申请日:2020-02-12
Applicant: Insulet Corporation
Inventor: Joon Bok Lee , Yibin Zheng , Jason O'Connor
Abstract: Exemplary embodiments described herein relate to a closed loop artificial pancreas system. The artificial pancreas system seeks to automatically and continuously control the blood glucose level of a user by emulating the endocrine functionality of a healthy pancreas. The artificial pancreas system uses a closed loop control system with a cost function. The penalty function helps to bound the infusion rate of insulin to attempt to avoid hypoglycemia and hyperglycemia. However, unlike conventional systems that use a generic or baseline parameter for a user's insulin needs in a cost function, the exemplary embodiments may use a customized parameter in the cost function that reflects the individualized insulin needs of the user. The use of the customized parameter causes the cost function to result in insulin dosages over time better suited to the individualized insulin needs of the user. This helps to better avoid hypoglycemia and hyperglycemia.
-
24.
公开(公告)号:US20210252219A1
公开(公告)日:2021-08-19
申请号:US16791648
申请日:2020-02-14
Applicant: Insulet Corporation
Inventor: Yibin ZHENG , Joon Bok LEE , Ashutosh ZADE , Jason O'Connor
Abstract: Exemplary embodiments may address the problem of missing blood glucose concentration readings from a glucose monitor that transmits blood glucose concentration readings over a wireless connection due to problems with the wireless connection. In the exemplary embodiments, an automated insulin delivery (AID) device uses an estimate in place of a missing blood glucose concentration reading in determining a predicted future blood glucose concentration reading for a user. Thus, the AID device is able to operate normally in generating insulin delivery settings despite not receiving a current blood glucose concentration reading for a current cycle. There is no need to suspend delivery of insulin to the user due to the missing blood glucose concentration reading.
-
公开(公告)号:US12257420B2
公开(公告)日:2025-03-25
申请号:US18436410
申请日:2024-02-08
Applicant: INSULET CORPORATION
Inventor: Joon Bok Lee , Mengdi Li , Jason O'Connor , Yibin Zheng
IPC: G08B1/08 , A61M5/172 , G16H10/40 , G16H10/60 , G16H20/17 , G16H40/60 , G16H40/67 , G16H50/20 , G16H50/30 , G16H50/50 , G16H50/70 , H04L67/141
Abstract: Disclosed are techniques to establish initial settings for an automatic insulin delivery device. An adjusted total daily insulin (TDI) factor usable to calculate a TDI dosage may be determined. The adjusted TDI factor may be a TDI per unit of a physical characteristic of the user (e.g., weight) times a reduction factor. The adjusted TDI factor may be compared to a maximum algorithm delivery threshold. Based on the comparison result, the application or algorithm may set a TDI dosage and output a control signal. Blood glucose measurement values may be collected from a sensor over a period of time. A level of glycated hemoglobin of the blood may be determined based on the obtained blood glucose measurement values. In response to the level of glycated hemoglobin, the set TDI dosage may be modified. A subsequent control signal including the modified TDI dosage may be output to actuate delivery of insulin.
-
公开(公告)号:US11992653B2
公开(公告)日:2024-05-28
申请号:US16515749
申请日:2019-07-18
Applicant: Insulet Corporation
Inventor: Jason O'Connor , Ian McLaughlin , Daniel Allis , David Nazzaro
CPC classification number: A61M5/14566 , A61M5/14248 , A61M5/1582 , A61M5/162 , A61M5/16881 , A61M2005/14252 , A61M2205/3379 , A61M2205/583
Abstract: Disclosed are examples for a system for drug delivery and components thereof. The system may include an on-body pump device and a secondary unit. The on-body pump device may include a reservoir and a fluid pathway. The reservoir may be configured to hold a liquid drug. The secondary unit may be removably coupled to the on-body pump device. The secondary unit may be configured to receive a prefilled cartridge containing a liquid drug, expel the liquid drug from the prefilled cartridge, and deliver the liquid drug to the reservoir of the on-body pump device via the fluid pathway. Examples of variations to the secondary unit are also disclosed.
-
公开(公告)号:US11957875B2
公开(公告)日:2024-04-16
申请号:US17112314
申请日:2020-12-04
Applicant: INSULET CORPORATION
Inventor: Yibin Zheng , Joon Bok Lee , Steven Cardinali , Jason O'Connor , Eric Benjamin , Ian McLaughlin , David Nazzaro , Ashutosh Zade
IPC: A61M5/172 , A61M5/142 , G01N33/49 , G16H10/60 , G16H20/17 , G16H20/60 , G16H40/40 , G16H40/67 , G16H50/30 , G16H50/70
CPC classification number: A61M5/1723 , A61M5/14248 , G01N33/49 , G16H10/60 , G16H20/17 , G16H20/60 , G16H40/40 , G16H40/67 , G16H50/30 , G16H50/70 , A61M2005/1726 , A61M2205/505 , A61M2205/52 , A61M2230/201
Abstract: Disclosed are a device, system, methods and computer-readable medium products that provide an updated insulin-to-carbohydrate ratio and an updated total daily insulin. The described processes may be used for periodic updating of the insulin-to-carbohydrate ratio and the total daily insulin. The insulin-to-carbohydrate ratio and/or the total may be used in the calculation of new doses of insulin that a drug delivery device may be commanded to deliver to a user.
-
公开(公告)号:US11883632B2
公开(公告)日:2024-01-30
申请号:US18159353
申请日:2023-01-25
Applicant: INSULET CORPORATION
Inventor: Jason O'Connor , Joon Bok Lee , Trang Ly , Yibin Zheng , Thomas Arnold Peyser , Jennifer Lena Schneider
CPC classification number: A61M5/1723 , A61B5/14532 , A61M5/145 , A61M5/14244 , A61B5/486 , A61B5/6832 , A61M2005/14208 , A61M2005/14252 , A61M2205/18 , A61M2205/52 , A61M2230/201
Abstract: Disclosed are a system, methods and computer-readable medium products that provide safety constraints for an insulin-delivery management program. Various examples provide safety constraints for a control algorithm-based drug delivery system that provides automatic delivery of a drug based on sensor input. Glucose measurement values may be received at regular time intervals from a sensor. A processor may predict future glucose values based on prior glucose measurement values. The safety constraints assist in safe operation of the drug delivery system during various operational scenarios. In some examples, predicted future glucose values may be used to implement safety constraints that mitigate under-delivery or over-delivery of the drug while not overly burdening the user of the drug delivery system and without sacrificing performance of the drug delivery system. Other safety constraints are also disclosed.
-
公开(公告)号:US11801344B2
公开(公告)日:2023-10-31
申请号:US16570125
申请日:2019-09-13
Applicant: Insulet Corporation
Inventor: Steven Cardinali , Joon Bok Lee , Jason O'Connor , Yibin Zheng
CPC classification number: A61M5/1723 , A61B5/14532 , G16H10/60 , G16H20/17 , A61B5/4839 , A61B5/683 , A61M5/14244 , A61M2005/14208 , A61M2005/1726 , A61M2205/52 , A61M2230/201 , G16H15/00
Abstract: Disclosed are a system, methods and computer-readable medium products that provide bolus dosage calculations by a control algorithm-based drug delivery system that provides automatic delivery of a drug, such as insulin or the like, based on sensor input. Blood glucose measurement values may be received at regular time intervals from a sensor. Using the blood glucose measurements, the control algorithm may perform various calculations and determinations to provide an appropriate bolus dosage. The appropriate bolus dosage may be used to respond to a trend in a trajectory of blood glucose measurements. In addition, a bolus dosage may also be determined by the disclosed device, system, method and/or computer-readable medium product in response to an indication that a user consumed a meal.
-
公开(公告)号:US11744944B2
公开(公告)日:2023-09-05
申请号:US16898529
申请日:2020-06-11
Applicant: Insulet Corporation
Inventor: Jason O'Connor , Daniel Allis , David Nazzaro , John R. Bussiere , John D'Arco
CPC classification number: A61M5/1723 , A61M5/14248 , G16H20/17 , G16H40/63 , A61M2205/27 , A61M2205/3569 , A61M2205/3584 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/8206 , A61M2230/201
Abstract: Systems and methods for automatically delivering medication to a user. A sensor coupled to a user can collect information regarding the user. A controller can use the collected information to determine an amount of medication to provide the user. The controller can instruct a drug delivery device to dispense the medication to the user. The drug delivery device can be a wearable insulin pump that is directly coupled to the user. The controller can be part of or implemented in a cellphone. A user can be required to provide a confirmation input to allow a determined amount of insulin to be provided to the user based on detected glucose levels of the user. The sensor, controller, and drug delivery device can communicate wirelessly.
-
-
-
-
-
-
-
-
-