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    NEURAL STIMULATION SYSTEM PROVIDING AUTO ADJUSTMENT OF STIMULUS OUTPUT AS A FUNCTION OF SENSED IMPEDANCE
    27.
    发明申请
    NEURAL STIMULATION SYSTEM PROVIDING AUTO ADJUSTMENT OF STIMULUS OUTPUT AS A FUNCTION OF SENSED IMPEDANCE 有权
    神经刺激系统提供刺激输出的自动调整作为感测阻抗的功能

    公开(公告)号：US20110190847A1

    公开(公告)日：2011-08-04

    申请号：US13069143

    申请日：2011-03-22

    Applicant: John D.H. King ,  James R. Thacker

    Inventor： John D.H. King ,  James R. Thacker

    IPC: A61N1/36

    CPC classification number: A61N1/36139 ,  A61N1/08 ,  A61N1/36071 ,  A61N1/3615

    Abstract: A neural stimulation system automatically corrects or adjusts the stimulus magnitude (stimulation energy) in order to maintain a comfortable and effective stimulation therapy. Because the changes in impedance associated with the electrode-tissue interface can indicate obstruction of current flow and positional lead displacement, lead impedance can indicate the quantity of electrical stimulation energy that should be delivered to the target neural tissue to provide corrective adjustment. Hence, a change in impedance or morphology of an impedance curve may be used in a feedback loop to indicate that the stimulation energy needs to be adjusted and the system can effectively auto correct the magnitude of stimulation energy to maintain a desired therapeutic effect.

    Abstract translation: 神经刺激系统自动校正或调整刺激量（刺激能量），以保持舒适有效的刺激疗法。 由于与电极 - 组织界面相关的阻抗变化可以指示电流和位置引线位移的阻塞，所以引线阻抗可以指示应该传送到目标神经组织的电刺激能量的量以提供校正调整。 因此，可以在反馈回路中使用阻抗曲线的阻抗或形态的变化，以指示需要调整刺激能量，并且系统能够有效地自动校正刺激能量的大小以维持所需的治疗效果。

    Neural stimulation system providing auto adjustment of stimulus output as a function of sensed pressure changes
    28.
    发明授权
    Neural stimulation system providing auto adjustment of stimulus output as a function of sensed pressure changes 有权
    神经刺激系统提供刺激输出的自动调整作为感测压力变化的函数

    公开(公告)号：US07801621B1

    公开(公告)日：2010-09-21

    申请号：US11742543

    申请日：2007-04-30

    Applicant: James R. Thacker ,  Carla Mann Woods

    Inventor： James R. Thacker ,  Carla Mann Woods

    IPC: A61N1/00

    CPC classification number: A61B5/6885 ,  A61B5/03 ,  A61N1/08 ,  A61N1/36128

    Abstract: A neural stimulation system automatically corrects or adjusts the stimulus magnitude in order to maintain a comfortable and effective stimulation therapy. Auto correction of the stimulus magnitude is linked to the measurement of pressure in the vicinity of the electrode-tissue interface. Because the pressure near the electrode-tissue interface can provide a measure of the electrode contacts' proximity to the neural tissue, and hence quantity of electrical energy delivered to the neural tissue, a change in the measured pressure or pressure morphology indicates that the stimulation energy may need to be adjusted. Hence, changes in pressure provide a feedback mechanism that permit the system to effectively auto correct the stimulus amplitude in order to maintain a desired therapeutic effect.

    Abstract translation: 神经刺激系统自动校正或调整刺激量值，以保持舒适有效的刺激治疗。 刺激大小的自动校正与电极组织界面附近的压力测量有关。 因为电极 - 组织界面附近的压力可以提供电极接触靠近神经组织的量度，并且因此提供给神经组织的电能量，测量的压力或压力形态的变化表明刺激能量 可能需要调整。 因此，压力变化提供了一种反馈机制，其允许系统有效地自动校正刺激振幅，以便保持期望的治疗效果。

    SYSTEM AND METHOD FOR CONVERTING TISSUE STIMULATION PROGRAMS IN A FORMAT USABLE BY AN ELECTRICAL CURRENT STEERING NAVIGATOR
    29.
    发明申请
    SYSTEM AND METHOD FOR CONVERTING TISSUE STIMULATION PROGRAMS IN A FORMAT USABLE BY AN ELECTRICAL CURRENT STEERING NAVIGATOR 有权
    用于电流转向导管可用的格式转换组织刺激方案的系统和方法

    公开(公告)号：US20100010566A1

    公开(公告)日：2010-01-14

    申请号：US12501282

    申请日：2009-07-10

    Applicant: James R. Thacker ,  Michael Moffitt ,  Kerry Bradley ,  David K.L. Peterson

    Inventor： James R. Thacker ,  Michael Moffitt ,  Kerry Bradley ,  David K.L. Peterson

    IPC: A61N1/08 ,  A61N1/34

    CPC classification number: A61N1/37264 ,  A61N1/36071 ,  A61N1/36146 ,  A61N1/3615 ,  A61N1/36167 ,  A61N1/36185 ,  A61N1/37247 ,  G06F19/00 ,  G16H40/63

    Abstract: A method, computer medium, and system for programming a controller is provided. The controller controls electrical stimulation energy output to electrodes, and stores a set of programmed stimulation parameters associated with the electrodes. The programmed stimulation parameter set is compared with sets of reference stimulation parameters, each of the reference sets of stimulation parameters being associated with the electrodes. If an identical match is determined between the programmed stimulation parameter set and any one of the reference stimulation parameter sets exists based on the comparison, the identically matched stimulation parameter set is selected as an initial stimulation parameter set. If an identical match does not exist, a best between the programmed stimulation parameter set and the reference stimulation parameter sets is determined and selected as the initial stimulation parameter set. The controller is then programmed with a new set of programmable stimulation parameters based on the initial stimulation parameter set.

    Abstract translation: 提供了一种用于编程控制器的方法，计算机介质和系统。 控制器控制对电极的电刺激能量输出，并且存储与电极相关联的一组编程的刺激参数。 将编程的刺激参数集与参考刺激参数的集合进行比较，每个参考组的刺激参数与电极相关联。 如果在编程的刺激参数集之间确定相同的匹配，并且基于比较存在参考刺激参数集中的任一个，则选择相同匹配的刺激参数集作为初始刺激参数集。 如果不存在相同的匹配，则确定编程的刺激参数集和参考刺激参数集之间的最佳值，并将其选为初始刺激参数集。 然后基于初始刺激参数集，控制器用一组新的可编程刺激参数进行编程。

    Apparatus and method for determining the relative position and orientation of neurostimulation leads
    30.
    发明授权
    Apparatus and method for determining the relative position and orientation of neurostimulation leads 有权

    公开(公告)号：US06993384B2

    公开(公告)日：2006-01-31

    申请号：US10310202

    申请日：2002-12-03

    Applicant: Kerry Bradley ,  James R. Thacker

    Inventor： Kerry Bradley ,  James R. Thacker

    IPC: A61N1/00

    CPC classification number: A61N1/08 ,  A61B5/053 ,  A61N1/0551

    Abstract: Interelectrode impedance or electric field potential measurements are used to determine the relative orientation of one lead to other leads in the spinal column or other body/tissue location. Interelectrode impedance is determined by measuring impedance vectors. The value of the impedance vector is due primarily to the electrode-electrolyte interface, and the bulk impedance between the electrodes. The bulk impedance between the electrodes is, in turn, made up of (1) the impedance of the tissue adjacent to the electrodes, and (2) the impedance of the tissue between the electrodes. In one embodiment, the present invention makes both monopolar and bipolar impedance measurements, and then corrects the bipolar impedance measurements using the monopolar measurements to eliminate the effect of the impedance of the tissue adjacent the electrodes. The orientation and position of the leads may be inferred from the relative minima of the corrected bipolar impedance values. These corrected impedance values may also be mapped and stored to facilitate a comparison with subsequent corrected impedance measurement values. Such comparison allows a determination to be made as to whether the lead position and/or orientation has changed appreciably over time. In another embodiment, one or more electrodes are stimulated and the resulting electric field potential on the non-stimulated electrodes is measured. Such field potential measurements provide an indication of the relative orientation of the electrodes. Once known, the relative orientation may be used to track lead migration, to setup stimulation configurations and parameters for nominal stimulation and/or navigation. Also, such measurements allow automatic adjustment of stimulation energy to a previously-defined optimal potential field in the case of lead migration or postural changes.

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