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44 条记录 (耗时 0.026 秒)

    Polymeric ophthalmic lens prepared from unsaturated polyoxyethylene monomers
    22.
    发明授权
    Polymeric ophthalmic lens prepared from unsaturated polyoxyethylene monomers 失效
    由不饱和聚氧乙烯单体制备的聚合物眼科镜片

    公开(公告)号：US5484863A

    公开(公告)日：1996-01-16

    申请号：US156135

    申请日：1993-11-22

    申请人： Frank F. Molock ,  Ivan M. Nunez ,  James D. Ford

    发明人： Frank F. Molock ,  Ivan M. Nunez ,  James D. Ford

    IPC分类号： C08F290/06 ,  G02B1/04 ,  C08F226/02 ,  C08F236/20 ,  G02C7/04

    CPC分类号： C08F290/062 ,  G02B1/043 ,  Y10S525/937

    摘要： A soft hydrogel contact lens, is disclosed. The lens is derived from a crosslinked polymer comprising the reaction product of a monomer mixture comprising:(A) a monounsaturated polyoxyethylene monomer;(B) a diunsaturated polyoxyethylene monomer of relatively high molecular weight;(C) a diunsaturated polyoxyethylene monomer of relatively low molecular weight; and(D) a hydrophilic monomer selected from the group consisting of hydroxyethyl methacrylate, methacrylic acid, N,N-dimethylacryiamide, N-vinyl pyrrolidone, glycerol monomethacrylate, itaconic acid, and mixtures thereof.

    摘要翻译： 公开了一种柔软的水凝胶隐形眼镜。 透镜衍生自包含单体混合物的反应产物的交联聚合物，所述单体混合物包含：（A）单不饱和聚氧乙烯单体; （B）相对较高分子量的二不饱和聚氧乙烯单体; （C）相对低分子量的二不饱和聚氧乙烯单体; 和（D）选自甲基丙烯酸羟乙酯，甲基丙烯酸，N，N-二甲基丙烯酰胺，N-乙烯基吡咯烷酮，单甲基丙烯酸甘油酯，衣康酸及其混合物的亲水性单体。

    Soft, high oxygen permeability ophtalmic lens
    23.
    发明授权
    Soft, high oxygen permeability ophtalmic lens 失效
    柔软，高透氧性透视镜

    公开(公告)号：US5304584A

    公开(公告)日：1994-04-19

    申请号：US979969

    申请日：1992-11-23

    申请人： Ivan M. Nunez ,  James D. Ford ,  Frank Molock

    发明人： Ivan M. Nunez ,  James D. Ford ,  Frank Molock

    IPC分类号： C07H15/08 ,  C07H15/10 ,  C08F290/00 ,  C08F299/02 ,  C08F299/06 ,  C08G18/48 ,  C08G18/50 ,  C08G18/65 ,  C08G18/81 ,  G02B1/04 ,  G02C7/04 ,  C08F24/00

    CPC分类号： C08G18/8158 ,  C08G18/4883 ,  G02B1/043

    摘要： A low water contact lens material having high O.sub.2 permeability, a lower water content and reduced polymer matrix size provides adequate O.sub.2 to the cornea, but does not wick water away from the eye nor allow protein or other tear components to penetrate and deposit in the lens. Such a lens is made by polymerizing and crosslinking a prepolymer which contains a cyclic polyol with polyalkylether segments containing curable segments. The cyclic polyols consist of alkoxylated glucose or sucrose which are then reacted with an isocyanate to produce an ultraviolet curable prepolymer. The prepolymer is then placed in a mold and polymerized by exposure to ultraviolet light. The free hydroxyl groups of the material react with a highly hydrophilic reagent to form covalent bonds thus making the surface of the material more wettable.

    摘要翻译： 具有高O 2渗透性，较低含水量和降低的聚合物基体尺寸的低水接触透镜材料为角膜提供足够的氧气，但不将水从眼睛吸出，也不允许蛋白质或其它泪液组分穿透并沉积在镜片中 。 通过使包含环状多元醇的预聚物与包含可固化链段的聚烷基醚链段聚合和交联来制造这种透镜。 环状多元醇由烷氧基化葡萄糖或蔗糖组成，然后与异氰酸酯反应生成紫外线固化预聚物。 然后将预聚物置于模具中并通过暴露于紫外光下聚合。 该材料的游离羟基与高亲水性试剂反应形成共价键，从而使材料的表面更易于润湿。

    Process for preparing vinyl chloroformate
    24.
    发明授权
    Process for preparing vinyl chloroformate 有权
    氯甲酸乙烯酯的制备方法

    公开(公告)号：US08273914B1

    公开(公告)日：2012-09-25

    申请号：US13169085

    申请日：2011-06-27

    申请人： Ivan M. Nunez ,  David E. Seelye

    发明人： Ivan M. Nunez ,  David E. Seelye

    IPC分类号： C07C69/63

    CPC分类号： C07C67/02 ,  C07C69/96

    摘要： Disclosed is a process for making vinyl chloroformate which includes reacting (a) a carbonyl compound of formula I: wherein R is a halogen or an alkyl group of 1 to about 25 carbon atoms; with (b) a silyl-containing enol ether and in the presence of an effective amount of a Group VIII-containing catalyst.

    摘要翻译： 公开了一种制备氯甲酸乙烯酯的方法，其包括使（a）式I的羰基化合物：其中R是卤素或1至约25个碳原子的烷基; 与（b）含甲硅烷基的烯醇醚，并且在有效量的含VIII族催化剂的存在下。

    POLYSILOXANES AND POLYSILOXANE PREPOLYMERS WITH VINYL OR EPOXY FUNCTIONALITY
    25.
    发明申请
    POLYSILOXANES AND POLYSILOXANE PREPOLYMERS WITH VINYL OR EPOXY FUNCTIONALITY 有权
    具有乙烯基或环氧官能团的多异氰酸酯和聚硅氧烷预聚物

    公开(公告)号：US20090227804A1

    公开(公告)日：2009-09-10

    申请号：US12042378

    申请日：2008-03-05

    申请人： Yu-Chin Lai ,  Edmond T. Quinn ,  Weihong Lang ,  Ivan M. Nunez

    发明人： Yu-Chin Lai ,  Edmond T. Quinn ,  Weihong Lang ,  Ivan M. Nunez

    IPC分类号： C07D303/02

    CPC分类号： C08G77/16 ,  C08G18/10 ,  C08G18/61 ,  C08G18/672 ,  C08G77/14 ,  C08G77/20 ,  C08G77/458

    摘要： Polysiloxanes having vinyl or epoxy functionality. The polysiloxanes are used to form polymer-based materials having properties particularly suited for biomedical device applications. The polysiloxanes are of general formula I: wherein R is a C2-10 alkenyl, a C2-10 alkyl with an epoxy group or a C5-C7cycloalkyl with an epoxy group; R2, R3 and R4 are each independently selected from the group consisting of hydrogen, C1-4 alkyl, C1-4 fluoroalkyl, optionally substituted phenyl and optionally substituted benzyl; A is —OH or —NHR5, wherein R5 is hydrogen or a C1-3 alkyl; and B is —R1-A or —R6, wherein R1 is a linking group having an alkylene group with 2 to 8 carbon atoms wherein the alkylene group optionally includes ether, urethane or ureido linkages; and R6 is selected from the group consisting of C1-4 alkyl, optionally substituted phenyl or optionally substituted benzyl; and m and n are integers with an m:n ratio from 30:1 to 3:1.

    摘要翻译： 具有乙烯基或环氧官能团的聚硅氧烷。 聚硅氧烷用于形成具有特别适用于生物医学装置应用的特性的聚合物基材料。 聚硅氧烷具有通式I：其中R是C2-10烯基，具有环氧基的C2-10烷基或具有环氧基的C5-C7环烷基; R 2，R 3和R 4各自独立地选自氢，C 1-4烷基，C 1-4氟烷基，任选取代的苯基和任选取代的苄基; A是-OH或-NHR 5，其中R 5是氢或C 1-3烷基; 并且B是-R1-A或-R6，其中R1是具有2至8个碳原子的亚烷基的连接基团，其中亚烷基任选地包括醚，氨基甲酸酯或脲基键; 并且R 6选自C 1-4烷基，任选取代的苯基或任选取代的苄基; m和n为30：1〜3：1的m：n比的整数。

    Polysiloxanes and polysiloxane prepolymers with vinyl or epoxy functionality
    30.
    发明授权
    Polysiloxanes and polysiloxane prepolymers with vinyl or epoxy functionality 有权
    具有乙烯基或环氧官能团的聚硅氧烷和聚硅氧烷预聚物

    公开(公告)号：US07781554B2

    公开(公告)日：2010-08-24

    申请号：US12042378

    申请日：2008-03-05

    申请人： Yu-Chin Lai ,  Edmond T. Quinn ,  Weihong Lang ,  Ivan M. Nunez

    发明人： Yu-Chin Lai ,  Edmond T. Quinn ,  Weihong Lang ,  Ivan M. Nunez

    IPC分类号： C08G77/00

    CPC分类号： C08G77/16 ,  C08G18/10 ,  C08G18/61 ,  C08G18/672 ,  C08G77/14 ,  C08G77/20 ,  C08G77/458

    摘要： Polysiloxanes having vinyl or epoxy functionality. The polysiloxanes are used to form polymer-based materials having properties particularly suited for biomedical device applications. The polysiloxanes are of general formula I: wherein R is a C2-10 alkenyl, a C2-10 alkyl with an epoxy group or a C5-C7cycloalkyl with an epoxy group; R2, R3 and R4 are each independently selected from the group consisting of hydrogen, C1-4 alkyl, C1-4 fluoroalkyl, optionally substituted phenyl and optionally substituted benzyl; A is —OH or —NHR5, wherein R5 is hydrogen or a C1-3 alkyl; and B is —R1-A or —R6, wherein R1 is a linking group having an alkylene group with 2 to 8 carbon atoms wherein the alkylene group optionally includes ether, urethane or ureido linkages; and R6 is selected from the group consisting of C1-4 alkyl, optionally substituted phenyl or optionally substituted benzyl; and m and n are integers with an m:n ratio from 30:1 to 3:1.

    摘要翻译： 具有乙烯基或环氧官能团的聚硅氧烷。 聚硅氧烷用于形成具有特别适用于生物医学装置应用的特性的聚合物基材料。 聚硅氧烷具有通式I：其中R是C2-10烯基，具有环氧基的C2-10烷基或具有环氧基的C5-C7环烷基; R 2，R 3和R 4各自独立地选自氢，C 1-4烷基，C 1-4氟烷基，任选取代的苯基和任选取代的苄基; A是-OH或-NHR 5，其中R 5是氢或C 1-3烷基; 并且B是-R1-A或-R6，其中R1是具有2至8个碳原子的亚烷基的连接基团，其中亚烷基任选地包括醚，氨基甲酸酯或脲基键; 并且R 6选自C 1-4烷基，任选取代的苯基或任选取代的苄基; m和n为30：1〜3：1的m：n比的整数。