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公开(公告)号:US09334242B2
公开(公告)日:2016-05-10
申请号:US12981233
申请日:2010-12-29
Applicant: Yan Lu , Chien-Ming Li , Zhao Wang , Jianjun Chen , Wei Li , James T. Dalton , Duane D. Miller , Charles Duke , Sunjoo Ahn
Inventor: Yan Lu , Chien-Ming Li , Zhao Wang , Jianjun Chen , Wei Li , James T. Dalton , Duane D. Miller , Charles Duke , Sunjoo Ahn
IPC: C07D233/64 , A61K31/4164 , A61K31/425 , A61K45/06 , C07D263/32 , C07D277/24 , C07D277/28 , C07D277/56 , C07D417/04
CPC classification number: C07D233/64 , A61K31/4164 , A61K31/425 , A61K45/06 , C07D263/32 , C07D277/24 , C07D277/28 , C07D277/56 , C07D417/04 , A61K2300/00
Abstract: The present invention relates to novel compounds having anti-cancer activity, methods of making these compounds, and their use for treating cancer and drug-resistant tumors, e.g. melanoma, metastatic melanoma, drug resistant melanoma, prostate cancer and drug resistant prostate cancer.
Abstract translation: 本发明涉及具有抗癌活性的新化合物,制备这些化合物的方法及其用于治疗癌症和药物抗性肿瘤的用途,例如, 黑素瘤,转移性黑素瘤,耐药性黑素瘤,前列腺癌和耐药前列腺癌。
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公开(公告)号:US08661136B2
公开(公告)日:2014-02-25
申请号:US13274385
申请日:2011-10-17
Applicant: Adwait Tumbde , Sahaya Andrews Albert , Adam Silberstein , Suryanarayan Perinkulam , Masood Mortazavi , Jianjun Chen , Russell Sears
Inventor: Adwait Tumbde , Sahaya Andrews Albert , Adam Silberstein , Suryanarayan Perinkulam , Masood Mortazavi , Jianjun Chen , Russell Sears
IPC: G06F15/16
CPC classification number: H04L67/1008 , G06F9/5083 , G06F11/3433 , G06F2209/508 , H04L67/101 , H04L67/1012
Abstract: Method, system, and programs for balancing work load in a distributed system. A plurality of multi-dimensional load metrics are received from a plurality of resource units in the distributed system. Based on the received plurality of multi-dimensional load metrics and a global statistical load model, a load deviance for each resource unit is computed. The plurality of resource units in the distributed system are then ranked based on the load deviance of each resource unit. At least one load balancing action is further determined based on the ranked resource units and at least one load balancing policy.
Abstract translation: 用于平衡分布式系统中工作负载的方法,系统和程序。 从分布式系统中的多个资源单元接收多个多维负载度量。 基于接收到的多维多尺度负载量度和全局统计负荷模型,计算每个资源单元的负荷偏差。 然后,基于每个资源单元的负载偏差对分布式系统中的多个资源单元进行排名。 基于排序的资源单元和至少一个负载平衡策略进一步确定至少一个负载平衡动作。
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公开(公告)号:US08592465B2
公开(公告)日:2013-11-26
申请号:US12485881
申请日:2009-06-16
Applicant: Duane D. Miller , Wei Li , Zhao Wang , Yan Lu , Jianjun Chen , James T. Dalton , Chien-Ming Li
Inventor: Duane D. Miller , Wei Li , Zhao Wang , Yan Lu , Jianjun Chen , James T. Dalton , Chien-Ming Li
IPC: C07D277/04 , C07D277/24 , A61K31/426
CPC classification number: C07D403/04 , A61K31/421 , A61K31/426
Abstract: Compounds according to formula (I) are disclosed where Q is S, N, or O; X is optional, and can be O═, S═, ═N—NH2, ═N—OH, or —OH; Y is optional and can be —N(H)—, O, or C1 to C20 hydrocarbon; and R1 and R2 are each independently substituted or unsubstituted single-, fused- or multiple-ring aryl or (hetero)cyclic ring systems. Methods of making these compounds, pharmaceutical compositions containing the compounds, and their use, particularly for treating or preventing cancer, are also disclosed.
Abstract translation: 公开了根据式(I)的化合物,其中Q是S,N或O; X是任选的,并且可以是O =,S =,= N-NH 2,= N-OH或-OH; Y是任选的,可以是-N(H) - ,O或C 1 -C 20烃; 且R 1和R 2各自独立地为取代或未取代的单,稠环或多环芳基或(杂)环系。 还公开了制备这些化合物的方法,含有这些化合物的药物组合物及其用途,特别是用于治疗或预防癌症的方法。
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公开(公告)号:US08346092B2
公开(公告)日:2013-01-01
申请号:US13240910
申请日:2011-09-22
Applicant: Ming Zhao , Jianjun Chen , Xueru Liu , Pinghua He
Inventor: Ming Zhao , Jianjun Chen , Xueru Liu , Pinghua He
IPC: H04B10/00
CPC classification number: H04B1/38 , H01Q1/246 , H01Q21/062 , H01Q21/28 , H04W88/085
Abstract: An antenna device is provided, which includes a first antenna unit and a second antenna unit. The first antenna unit includes a first radiation module, a power divider/combiner network connected to the first radiation module, and a feeder interface connected to the power divider/combiner network. The feeder interface is connected to a radio remote unit (RRU) or a macro base station through a feeder. The second antenna unit includes a second radiation module, a transceiver array connected to the second radiation module, a baseband processing unit (BPU) connected to the transceiver array, and an optical fiber interface connected to the BPU. The optical fiber interface is connected to a baseband unit (BBU) through an optical fiber. Therefore, after the existing passive antenna is replaced by the provided antenna device, the RRU or macro base station in the original network can still be used, which reduces waste of resources.
Abstract translation: 提供一种天线装置,其包括第一天线单元和第二天线单元。 第一天线单元包括第一辐射模块,连接到第一辐射模块的功率分配器/组合器网络,以及连接到功率分配器/组合器网络的馈线接口。 馈线接口通过馈线连接到无线电远程单元(RRU)或宏基站。 第二天线单元包括第二辐射模块,连接到第二辐射模块的收发器阵列,连接到收发器阵列的基带处理单元(BPU)和连接到BPU的光纤接口。 光纤接口通过光纤连接到基带单元(BBU)。 因此,在现有无源天线被所提供的天线设备替代之后,仍然可以使用原始网络中的RRU或宏基站,从而减少资源的浪费。
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公开(公告)号:USPP22825P3
公开(公告)日:2012-06-26
申请号:US12799315
申请日:2010-04-21
Applicant: Richard Henny , Jianjun Chen
Inventor: Richard Henny , Jianjun Chen
IPC: A01H5/00
CPC classification number: A01H5/12
Abstract: A new and distinct variety of Aglaonema plant, denominated ‘UF-808-4’, characterized by medium sized and upright plant growth habit, vigorous and dense growth habit, dark green-colored leaves with large grey green-colored venal areas covering over half the leaf surface, and petioles and stems possessing numerous white spots.
Abstract translation: 一种新颖独特的Aglaonema植物,称为“UF-808-4”,其特征是中等大小和直立的植物生长习性,生长繁茂的生长习性,深绿色的叶子与大的灰绿色的静脉区域覆盖了一半以上 叶表面,叶柄和茎具有许多白点。
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公开(公告)号:US20110265232P1
公开(公告)日:2011-10-27
申请号:US12799315
申请日:2010-04-21
Applicant: Richard Henny , Jianjun Chen
Inventor: Richard Henny , Jianjun Chen
IPC: A01H5/00
CPC classification number: A01H5/12
Abstract: A new and distinct variety of Aglaonema plant, denominated ‘UF-808-4’, characterized by medium sized and upright plant growth habit, vigorous and dense growth habit, dark green-colored leaves with large grey green-colored venal areas covering over half the leaf surface, and petioles and stems possessing numerous white spots.
Abstract translation: 一种新颖独特的Aglaonema植物,称为“UF-808-4”,其特征是中等大小和直立的植物生长习性,生长繁茂的生长习性,深绿色的叶子与大的灰绿色的静脉区域覆盖了一半以上 叶表面,叶柄和茎具有许多白点。
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公开(公告)号:USPP21217P2
公开(公告)日:2010-08-17
申请号:US12316132
申请日:2008-12-09
Applicant: Richard Henny , Jianjun Chen
Inventor: Richard Henny , Jianjun Chen
IPC: A01H5/00
CPC classification number: A01H5/00
Abstract: A new Epipremnum plant particularly distinguished by having small variegated leaves with three different colors, irregularly undulated rather than smooth leaf surfaces, and compact and dense growth habit, is disclosed.
Abstract translation: 公开了一种新的Epipremnum植物,其特征在于具有三种不同颜色的小杂色叶,不规则地起伏而不是光滑的叶表面,以及致密和致密的生长习性。
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公开(公告)号:USPP20916P2
公开(公告)日:2010-04-06
申请号:US12315708
申请日:2008-12-04
Applicant: Richard Henny , Jianjun Chen
Inventor: Richard Henny , Jianjun Chen
IPC: A01H5/00
CPC classification number: A01H5/00
Abstract: A new Philodendron plant particularly distinguished by having very small, narrow green leaves, compact vines with short internodes and dense growth habit, and vines that produce lateral branches, is disclosed.
Abstract translation: 公开了一种新的Philodendron植物,其特征在于具有非常小的,窄的绿色叶子,具有短的节间和致密的生长习性的紧密的葡萄藤以及产生侧枝的葡萄藤。
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公开(公告)号:USPP20463P2
公开(公告)日:2009-11-10
申请号:US12231142
申请日:2008-08-29
Applicant: Richard Henny , Jianjun Chen
Inventor: Richard Henny , Jianjun Chen
IPC: A01H5/00
Abstract: A new and distinct variety of Aglaonema, denominated ‘UF-742-3’, has small to medium size and upright plant growth habit, vigorous and dense growth habit, very freely clumping habit, dark green-colored leaves with large grey green-colored venal areas covering over half the leaf surface, and white colored petioles.
Abstract translation: 一种新颖独特的Aglaonema品种,称为“UF-742-3”,具有中小尺寸和直立的植物生长习性,生长密集的生长习性,非常自由的结块习性,深绿色的叶子,具有大的灰绿色 覆盖半个叶面的病区,以及白色的叶柄。
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